Abstract:
BACKGROUND:Improvement of left ventricular (LV) systolic dysfunction can occur in patients with dilated cardiomyopathy (DCM), and it is more frequently observed if patients have no delayed enhancement (DE) in cardiac magnetic resonance imaging (CMR). However, even in the absence of DE, not all patients have functional recovery. We retrospectively investigated the predictors of LV functional recovery in patients with DCM who had no DE in CMR. METHODS:A total of 136 patients with DCM underwent CMR. Among them, 44 (29 male, age 55 ± 14 years) showed no DE and these patients composed the study population. The study patients were divided into 2 groups according to the occurrence of functional recovery defined as an increase in LV ejection fraction to a level of ≥50% and net increase in ejection fraction of 20% or more: group 1 (n = 14) with functional recovery and group 2 (n = 30) without functional recovery. RESULTS:In patients who showed functional recovery, left atrial volume index (LAVI [26 ± 8 mL/m(2) vs 45 ± 18 mL/m(2)]) and LV end-diastolic dimension (62 ± 6 mm vs 67 ± 7 mm) were significantly smaller when compared with those without functional recovery (P <.05 for all). In Cox multiple regression analysis, LAVI was the only significant parameter associated with LV functional recovery (hazard ratio 0.932, 95% confidence interval 0.877-0.991, P = .024). LAVI < 38 mL/m(2) had 100% specificity in predicting the improvement of LV systolic dysfunction. CONCLUSION:In DCM patients who had no DE in CMR, LAVI predicts LV functional recovery with high specificity.
journal_name
J Card Failjournal_title
Journal of cardiac failureauthors
Moon J,Shim CY,Kim YJ,Park S,Kang SM,Chung N,Ha JWdoi
10.1016/j.cardfail.2015.12.011subject
Has Abstractpub_date
2016-04-01 00:00:00pages
265-71issue
4eissn
1071-9164issn
1532-8414pii
S1071-9164(15)01220-8journal_volume
22pub_type
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journal_title:Journal of cardiac failure
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journal_title:Journal of cardiac failure
pub_type: 杂志文章,多中心研究
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journal_title:Journal of cardiac failure
pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:Journal of cardiac failure
pub_type: 杂志文章,多中心研究
doi:10.1016/j.cardfail.2011.04.001
更新日期:2011-05-01 00:00:00
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journal_title:Journal of cardiac failure
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journal_title:Journal of cardiac failure
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journal_title:Journal of cardiac failure
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更新日期:2011-01-01 00:00:00
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journal_title:Journal of cardiac failure
pub_type: 杂志文章,评审
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journal_title:Journal of cardiac failure
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