The Correlations Between MRI Perfusion, Diffusion Parameters, and 18F-FDG PET Metabolic Parameters in Primary Head-and-Neck Cancer: A Cross-Sectional Analysis in Single Institute.

Abstract:

:This study aimed to investigate the relationships among parameters from dynamic contrast-enhanced (DCE) MRI, diffusion-weighted MRI (DWI), and F-fluorodeoxyglucose (F-FDG) PET in patients with primary head-and-neck squamous cell carcinoma (HNSCC).A total of 34 patients with primary HNSCC underwent DCE-MRI, DWI, and F-FDG PET before treatment. The perfusion parameters (Ktrans, Ktransmax, Kep, Ve, Vp, and AUC60) from DCE-MRI and ADC (ADCmean, ADCmin) values from DWI were calculated within the manually placed ROI around the main tumor. Standardized uptake value (SUVmax, SUVmean), metabolic tumor volume (MTV), and total lesion glycolysis (TLG = SUVmean × MTV) were calculated with thresholds of 3.0 SUV. The associations between parameters were evaluated by Pearson correlation analysis.Significant correlations were identified between Ktrans and Kep (r = 0.631), Ktrans and Ve (r = 0.603), Ktrans and ADCmean (r = 0.438), Ktransmax and Kep (r = 0.667), Ktransmax and Vp (r = 0.351), Ve and AUC60 (r = 0.364), Ve and ADCmean (r = 0.590), and Ve and ADCmin (r = 0.361). ADCmin was reversely correlated with TLG (r = -0.347). Tumor volume was significantly associated with Ktransmax (r = 0.348).The demonstrated relationships among parameters from DCE, DWI, and F-FDG PET suggest complex interactions among tumor biologic characteristics. Each diagnostic technique may provide complementary information for HNSCC.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Han M,Kim SY,Lee SJ,Choi JW

doi

10.1097/MD.0000000000002141

subject

Has Abstract

pub_date

2015-11-01 00:00:00

pages

e2141

issue

47

eissn

0025-7974

issn

1536-5964

pii

00005792-201511240-00064

journal_volume

94

pub_type

杂志文章

相关文献

MEDICINE文献大全
  • Keyhole approach in the neuroendoscopic treatment for hydrocephalus.

    abstract::The aim of the study was to explore keyhole approach and dura suture in the neuroendoscopic treatment for hydrocephalus.Twelve cases of hydrocephalus patients who were treated with neuroendoscope by this approach were analyzed retrospectively from April 2015 to April 2016 in our department. The basic steps of this pro...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000005823

    authors: Cai Q,Zhang X,Wang L,Huang S,Chen Z,Chen Q

    更新日期:2017-01-01 00:00:00

  • Can high social capital at the workplace buffer against stress and musculoskeletal pain?: Cross-sectional study.

    abstract::Work-related musculoskeletal pain and stress are both highly prevalent in the working environment and relate well to the biopsychosocial model. While the onset of musculoskeletal pain is often dependent on the biological element of the biopsychosocial model, chronic pain is often influenced by psychological and social...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000010124

    authors: Jay K,Andersen LL

    更新日期:2018-03-01 00:00:00

  • Risk factors for osteoporosis in liver cirrhosis patients measured by transient elastography.

    abstract::Osteoporosis or osteopenia is a common complication in patients with cirrhosis, but little is known about the risk factors for the occurrence of osteoporosis.Patients with liver cirrhosis due to chronic virus infection and alcoholic abuse were enrolled. Bone mineral density (BMD) was determined using dual-energy x-ray...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000010645

    authors: Zheng JP,Miao HX,Zheng SW,Liu WL,Chen CQ,Zhong HB,Li SF,Fang YP,Sun CH

    更新日期:2018-05-01 00:00:00

  • Increased risk of ventricular tachycardia and cardiovascular death in patients with myocarditis during the long-term follow-up: A national representative cohort from the National Health Insurance Research Database.

    abstract::The incidence of acute myocarditis complicated with ventricular tachycardia (VT) is unknown. This study aimed to investigate the association between myocarditis and the incidence of VT and mortality. We also aimed to determine the independent predictors that increased the VT risk in those patients. From 2000 to 2004, ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000006633

    authors: Te ALD,Wu TC,Lin YJ,Chen YY,Chung FP,Chang SL,Lo LW,Hu YF,Tuan TC,Chao TF,Liao JN,Chien KL,Lin CY,Chang YT,Chen SA

    更新日期:2017-05-01 00:00:00

  • Correlation of ultrasound features and the Risk of Ovarian Malignancy Algorithm score for different histopathological subtypes of benign adnexal masses.

    abstract::Ovarian masses are one of the most frequently identified entities in gynecological practice. Early differential diagnosis is a key factor in the medical management of each patient. Transvaginal ultrasound along with additional preoperative testing, such as serum cancer antigen 125 (CA-125) levels and the Risk of Ovari...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000011762

    authors: Ionescu CA,Matei A,Navolan D,Dimitriu M,Bohâltea R,Neacsu A,Ilinca C,Ples L

    更新日期:2018-08-01 00:00:00

  • Complete clinical and functional recovery following low-dose methotrexate related paraparesis in a patient with compound c.1298A>C AND c.677C>T MTHFR polymorphism: A case report.

    abstract:RATIONALE:The mechanisms of action of MTX (methotrexate) in the treatment of RA (rheumatoid arthritis) and PsA (psoriatic arthritis) is related to its antifolic activity, due to the high affinity for enzymes that require folate cofactors as dihydrofolate reductase and to the anti-inflammatory activity derivated from th...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000013350

    authors: Saviola G,Abdi-Ali L,Sacco S,Comini L,Plewnia K,Rossi M,Orrico A

    更新日期:2018-12-01 00:00:00

  • Continuous cervical epidural block: Treatment for intractable hiccups.

    abstract::Intractable hiccups, although rare, may result in severe morbidity, including sleep deprivation, poor food intake, respiratory muscle fatigue, aspiration pneumonia, and death. Despite these potentially fatal complications, the etiology of intractable hiccups and definitive treatment are unknown. This study aimed to ev...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000009444

    authors: Kim JE,Lee MK,Lee DK,Choi SS,Park JS

    更新日期:2018-02-01 00:00:00

  • Epidemiology and clinical characteristics of traumatic brain injury in Lebanon: A systematic review.

    abstract:BACKGROUND:Traumatic brain injury (TBI) is a debilitating medical and emerging public health problem that is affecting people worldwide due to a multitude of factors including both domestic and war-related acts. The objective of this paper is to systematically review the status of TBI in Lebanon - a Middle Eastern coun...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0000000000005342

    authors: Abou-Abbass H,Bahmad H,Ghandour H,Fares J,Wazzi-Mkahal R,Yacoub B,Darwish H,Mondello S,Harati H,El Sayed MJ,Tamim H,Kobeissy F

    更新日期:2016-11-01 00:00:00

  • Sonography-guided trigger point injections in abdominal myofascial pain syndrome.

    abstract::Even though chronic abdominal pain is 1 of the most common reasons for hospital visits, diagnostic testing is often time-consuming and treatment is inadequate. Abdominal myofascial pain syndrome (AMPS) is usually not included as a differential diagnosis, but it should be considered in cases of chronic abdominal pain. ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000023408

    authors: Rhim HC,Cha JH,Cha J,Kim DH

    更新日期:2020-12-04 00:00:00

  • Preoperative prealbumin and transferring: Relation to 30-day risk of complication in elective spine surgical patients.

    abstract:OF BACKGROUND DATA:There is growing interest in identifying nutritional biomarkers associated with poor outcomes of elective spine surgery. Prealbumin and transferrin are both biomarkers of nutritional status that can be obtained from clinical laboratories. However, associations of preoperative measures of these nutrit...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000014741

    authors: Takemoto E,Yoo J,Blizzard SR,Shannon J,Marshall LM

    更新日期:2019-03-01 00:00:00

  • Antiretroviral treatment and its impact on oral health outcomes in 5 to 7 year old Ugandan children: A 6 year follow-up visit from the ANRS 12174 randomized trial.

    abstract:BACKGROUND:Antiretroviral therapy for HIV in sub-Saharan Africa has transformed the highly infectious virus to a stable chronic condition, with the advent of Highly active antiretroviral therapy (HAART). The longterm effects of HAART on the oral health of children are understudied. OBJECTIVE:To compare the effect of l...

    journal_title:Medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/MD.0000000000022352

    authors: Birungi N,Fadnes LT,Engebretsen IMS,Tumwine JK,Åstrøm AN,for ANRS 12174 AND 12341 study groups.

    更新日期:2020-09-25 00:00:00

  • Increasing efficacy and reducing side effects in treatment of chronic anal fissures: A study of topical diazepam therapy.

    abstract::This is a single institution nonexperimental study intended to analyze the therapeutic efficacy of topical diazepam in treating symptoms of chronic anal fissures.Anal fissures are a common cause of anal pain. Conventional treatments include nonsteroidal anti-inflammatory drugs, topical creams, such as nitroglycerin an...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000006853

    authors: Hang MTH,Smith BE,Keck C,Keshavarzian A,Sedghi S

    更新日期:2017-05-01 00:00:00

  • Treatment of distal radioulnar joint dislocation with spontaneous rupture of extensor tendon by Sauve-Kapandji osteotomy assisted by wrist arthroscopy: A case series and literature review.

    abstract:RATIONALE:Dislocation of the distal radioulnar joint and injury to distal forearm are commonly encountered. However, delayed diagnosis or misdiagnosis has been relatively rare due to improved diagnosis and treatment. Treatment of old dislocation of radioulnar joint is challenging due to development of secondary chronic...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000010752

    authors: Qian H,Chen G,Liu Z

    更新日期:2018-06-01 00:00:00

  • Is retrograde drilling really useful for osteochondral lesion of talus with subchondral cyst?: A case report.

    abstract:RATIONALE:Retrograde drilling is a well accepted procedure for osteochondral lesion of the talus and subchondral cyst with intact overlying cartilage. It has good results in most reports. Compared to anterograde drilling, retrograde drilling can protect the integrity of the articular cartilage. The purpose of this stud...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000005418

    authors: Jeong SY,Kim JK,Lee KB

    更新日期:2016-12-01 00:00:00

  • The hepatic protective effects of tacrolimus as a rinse solution in liver transplantation: A meta-analysis.

    abstract:BACKGROUND:Tacrolimus was used as a rinse solution against ischaemia-reperfusion injury (IRI) in liver transplantation for years but its protective effects remain controversies. METHODS:We conducted literature retrieval in electronic databases including MEDLINE, EMBASE and Cochrane Central to identify relevant randomi...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000015809

    authors: Guo T,Lei J,Gao J,Li Z,Liu Z

    更新日期:2019-05-01 00:00:00

  • Transcriptome analyses identify hub genes and potential mechanisms in adenoid cystic carcinoma.

    abstract::Adenoid cystic carcinoma (ACC) is one of the most frequent malignancies of salivary glands. The objective of this study was to identify key genes and potential mechanisms during ACC samples.The gene expression profiles of GSE88804 data set were downloaded from Gene Expression Omnibus. The GSE88804 data set contained 2...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000018676

    authors: Liu HB,Huang GJ,Luo MS

    更新日期:2020-01-01 00:00:00

  • Onodi cell mucocele causing isolated trochlear nerve palsy: A case report.

    abstract:RATIONALE:Acquired vertical diplopia is commonly observed in trochlear nerve palsy, often resulting from blunt head trauma or vascular problems. It is rarely caused by tumorous conditions or space occupying lesion. We report the first case of Onodi cell mucocele causing isolated trochlear nerve palsy. PATIENT CONCERNS...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000015475

    authors: Kwon KW,Oh JS,Kim JW,Yoo RE,Kang JG

    更新日期:2019-05-01 00:00:00

  • An ovarian Leydig cell tumor of ultrasound negative in a postmenopausal woman with hirsutism and hyperandrogenism: A case report.

    abstract:RATIONALE:The incidence of severe hyperandrogenism associated with masculinity in women is very low. While rare and difficult to diagnose, androgen secreting tumors should be suspected in women with hyperandrogenism and hirsutism, especially in the postmenopausal population. Herein we present one case of ovarian Leydig...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000010093

    authors: Chen M,Zhou W,Zhang Z,Zou Y,Li C

    更新日期:2018-03-01 00:00:00

  • High 25-hydroxyvitamin D is associated with unexpectedly high plasma inflammatory markers in HIV patients on antiretroviral therapy.

    abstract::Inflammation associated with low 25-hydroxyvitamin D (25(OH)D) is associated with increased morbidity and mortality among HIV-infected patients with vitamin D deficiency. We investigated the association between 25(OH)D and soluble biomarkers among HIV-infected patients on stable antiretroviral therapy. This is a cross...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000005270

    authors: Gangcuangco LMA,Kohorn LB,Chow DC,Keating SM,Norris PJ,Nagamine LS,Ndhlovu LC,Souza SA,Kallianpur KJ,Shikuma CM

    更新日期:2016-10-01 00:00:00

  • Association between the persistent organic pollutants and polycystic ovary syndrome: A protocol for a systematic review and meta-analysis.

    abstract:BACKGROUND:Current evidence concerning the association between persistent organic pollutants (POPs) and polycystic ovary syndrome (PCOS) is inconsistent. The aim of the present systematic review and meta-analysis is to evaluate the role of POPs in PCOS. METHODS:Databases including PubMed, Embase, Web of Science, and C...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000016948

    authors: Li Y,Zhang MW,Wang YJ

    更新日期:2019-08-01 00:00:00

  • Management of the axilla with sentinel lymph node biopsy after neoadjuvant chemotherapy for breast cancer: A single-center study.

    abstract::The neoadjuvant chemotherapy (NAC) is the gold standard initial treatment of the locally advanced breast cancer (LABC). However, the reliability of methods that used to assess response the NAC is still controversial. In this study, patients with LABC who underwent NAC were evaluated retrospectively. The assessment of ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000023538

    authors: Aksoy SO,Sevinc Aİ,Ünal M,Balci P,Görkem İB,Durak MG,Ozer O,Bekiş R,Emir B

    更新日期:2020-12-04 00:00:00

  • The poor prognosis of the primary gastric epithelioid angiosarcoma: A case report.

    abstract:RATIONALE:Primary gastric epithelioid angiosarcoma is a highly aggressive endothelial cell malignancy and may pose a great diagnostic challenge. PATIENT CONCERNS:Here we describe the case of a 56-year-old man presented with melena and epigastric dull pain for 2 weeks. DIAGNOSIS:Primary gastric epithelioid angiosarcom...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000010287

    authors: Xia J,Shi D,Wu Z,Chen Y,Liu B,Chen L,Metta W,Zheng Y

    更新日期:2018-04-01 00:00:00

  • A novel dermato-pulmonary syndrome associated with MDA-5 antibodies: report of 2 cases and review of the literature.

    abstract::Melanoma differentiation-associated protein 5 (MDA-5) is a novel autoantibody frequently characterized by interstitial lung disease and a distinct cutaneous phenotype with palmar papules, ulceration, and rash. Virtually all patients have underlying dermatomyositis, but many lack the characteristic clinical myopathy as...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0b013e3182606f0b

    authors: Chaisson NF,Paik J,Orbai AM,Casciola-Rosen L,Fiorentino D,Danoff S,Rosen A

    更新日期:2012-07-01 00:00:00

  • Effects of mirror therapy on muscle activity, muscle tone, pain, and function in patients with mutilating injuries: A randomized controlled trial.

    abstract:BACKGROUND:This study assessed the effectiveness of mirror therapy (MT) on muscle elasticity, pain, and function in patients with mutilating injuries. METHODS:Thirty patients with impaired function due to mutilating injuries were assigned randomly to experimental or control group. The experimental group (n = 15) recei...

    journal_title:Medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MD.0000000000015157

    authors: Yun DE,Kim MK

    更新日期:2019-04-01 00:00:00

  • Rates of initial and recurrent thromboembolic disease among patients with malignancy versus those without malignancy. Risk analysis using Medicare claims data.

    abstract::Although the association between malignancy and thromboembolic disease is well established, the relative risk of developing initial and recurrent deep vein thrombosis (DVT) or pulmonary embolism (PE) among patients with malignancy versus those without malignancy has not been clearly defined. The Medicare Provider Anal...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/00005792-199909000-00001

    authors: Levitan N,Dowlati A,Remick SC,Tahsildar HI,Sivinski LD,Beyth R,Rimm AA

    更新日期:1999-09-01 00:00:00

  • Association between uterine leiomyoma and metabolic syndrome in parous premenopausal women: A case-control study.

    abstract::Previous studies have reported that uterine leiomyoma (UL) may share pathogenic features with obesity and hypertension, which are components of metabolic syndrome (MetS). We examined the association between UL and MetS in premenopausal parous women.This 1:1 case-control study was conducted on 615 asymptomatic women wi...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000005325

    authors: Tak YJ,Lee SY,Park SK,Kim YJ,Lee JG,Jeong DW,Kim SC,Kim IJ,Yi YH

    更新日期:2016-11-01 00:00:00

  • Current trends in health coaching for chronic conditions: A systematic review and meta-analysis of randomized controlled trials.

    abstract:BACKGROUND:Chronic conditions are placing a serious burden on individuals as well as the health care system. Health coaching (HC) has emerged as a promising approach that can support effective lifestyle interventions for chronic conditions. However, until now there is no particularly comprehensive systematic review of ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000021080

    authors: Yang J,Bauer BA,Lindeen SA,Perlman AI,Abu Dabrh AM,Boehmer KR,Salinas M,Cutshall SM

    更新日期:2020-07-24 00:00:00

  • Invasive bacterial infections in Gambians with sickle cell anemia in an era of widespread pneumococcal and hemophilus influenzae type b vaccination.

    abstract::There is relatively little data on the etiology of bacterial infections in patients with sickle cell anemia (SCA) in West Africa, and no data from countries that have implemented conjugate vaccines against both Streptococcus pneumoniae and Haemophilus influenzae type b (Hib).We conducted a retrospective analysis of SC...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000005512

    authors: Soothill G,Darboe S,Bah G,Bolarinde L,Cunnington A,Anderson ST

    更新日期:2016-12-01 00:00:00

  • The constitution and functional prediction of the microbiota in necrotizing enterocolitis with a gestational age of over 28 weeks.

    abstract:BACKGROUND:To explore the features and function of gut microbiota in necrotizing enterocolitis patients over 28 gestational age weeks through a case-control study. METHODS:Fecal samples from patients with NEC over 28 gestational week age and matched control cases were collected. DNA of the fecal samples was extracted ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000017206

    authors: Feng J,He Y,Liu D,Li L,Chen J,Yu J

    更新日期:2019-10-01 00:00:00

  • Effect of Probiotics on Blood Lipid Concentrations: A Meta-Analysis of Randomized Controlled Trials.

    abstract::Previous clinical studies have reported mixed results regarding the effect of probiotics on lipid metabolism. Therefore, we conducted a meta-analysis of randomized controlled trials to quantify the direction and magnitude of the potential effect of probiotics on blood lipid concentrations.Eligible studies were randomi...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000001714

    authors: Cho YA,Kim J

    更新日期:2015-10-01 00:00:00