Abstract:
:Metastasizing tumor cells lose expression of the tumor suppressor PTEN at a much higher rate when they enter the brain compared to other organs, suggesting that the brain's unique microenvironment may prime metastatic cells for aggressive growth, a recent study reports. The findings may have implications for developing targeted therapies for brain metastases.
journal_name
Cancer Discovjournal_title
Cancer discoveryauthors
doi
10.1158/2159-8290.CD-NB2015-163subject
Has Abstractpub_date
2016-01-01 00:00:00pages
OF2issue
1eissn
2159-8274issn
2159-8290pii
2159-8290.CD-NB2015-163journal_volume
6pub_type
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