Abstract:
:Hypoxia-inducible factors (HIF) have long been linked to malignant tumor phenotypes in various cancer types, and several downstream mediators of HIF action are deregulated in metastatic carcinomas. A new study links hypoxia-induced collagen remodeling to sarcoma progression, providing evidence for unifying mechanisms of carcinoma and sarcoma metastasis.
journal_name
Cancer Discovjournal_title
Cancer discoveryauthors
Vanharanta S,Massagué Jdoi
10.1158/2159-8290.CD-13-0481subject
Has Abstractpub_date
2013-10-01 00:00:00pages
1103-4issue
10eissn
2159-8274issn
2159-8290pii
3/10/1103journal_volume
3pub_type
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