[A heparin-glucuronylglucosaminoglycan combination for topical use. An evaluation of the therapeutic effects in induced experimental muscle damage and in minor sports injuries].

Abstract:

:The aim of the study was to evaluate the clinical efficacy of the association of heparin and sulodexide on experimental pain and on "small sport traumatology". In the experimental part of the study, cutaneous pain threshold and subcutaneous tissue ticking were measured after the induction of an algogenic focus in deep somatic side. In the clinical part of the study, pain intensity (by A.V. scale), athletic performance and therapy duration, in athletes from muscular or articular posttraumatic injuries, were also assessed. After the therapy with the examined drug, a less significant lowering of cutaneous pain threshold and a less subcutaneous tissue thickening were found in the experimental study; in the clinical study a significant reduction of pain intensity and a quick restore of athletic performance were revealed. These results allow to conclude that the drug in effective to reduce painful symptomatology in both experimental and clinical conditions, by the limitation of some aspects of inflammation.

journal_name

Minerva Med

journal_title

Minerva medica

authors

Dragani L,Colozzi A,Schiavone C,Obletter G,Celiberti V,Radico S,Vecchiet L

subject

Has Abstract

pub_date

1989-04-01 00:00:00

pages

397-403

issue

4

eissn

0026-4806

issn

1827-1669

journal_volume

80

pub_type

临床试验,杂志文章
  • The glaucomas.

    abstract::Glaucoma is the leading cause of irreversible blindness worldwide. The World Health Organization reported in 1995 that 5.1 million persons were bilaterally blind from glaucoma. Its morbidity and prevalence make it a significant public health problem. Because it is a treatable condition, it is important that medical pr...

    journal_title:Minerva medica

    pub_type: 杂志文章,评审

    doi:

    authors: Coleman AL,Brigatti L

    更新日期:2001-10-01 00:00:00

  • [Controlled study of the analgesic effect and tolerability of buprenorphine in cancer patients].

    abstract::The analgesic efficacy and tolerability of a morphine agonist-antagonist buprenorphine are evaluated. The drug is compared to pentazocin. For this purpose, the drugs were randomly administered to 42 patients suffering from pain caused by advanced cancer. Buprenorphine demonstrated a significantly higher analgesic effe...

    journal_title:Minerva medica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Dini D,Fassio T,Gottlieb A,Gini M

    更新日期:1986-01-28 00:00:00

  • [Behavior of hematocrit values in chronic bronchopneumatic patients during administration of saluretics].

    abstract::Changes in haematocrit values were determined in chronic bronchitis patients undergoing water depletion with diuretics. Unchanged, increased and decreased values were observed. The results were statistically significant and indicated that: 1) increases correspond to a decrease in the amount of extracellular water; 2) ...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Fumagalli G,Ferrara A,Bossi R

    更新日期:1974-12-22 00:00:00

  • [Electro-acupuncture and trophic ulcer].

    abstract::Electroacupuncture was used in the treatment of 50 cases of tropic ulcer of the lower extremities, including 34 following phlebitis, by stimulation with a Roccia VTM apparatus at voltages and frequencies up to the patient's tolerance threshold. The needles stimulation was maintained for a maximum of 7 hr. A cure was o...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Di Bernardo N,Ferlazzo F,Biondo G,Cucinotta E,De Meo A

    更新日期:1980-12-22 00:00:00

  • [Inappropriate drug use in elderly patients. Considerations on various psychologic aspects].

    abstract::The paper examines the hypothesis that inappropriate drug taking by elderly patients may be related to particular psychological motivations. On the one hand, this may aim to confirm their own "status" as patients for the secondary advantages brought about by illness (attention from other members of the family), even t...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Liffredo C,Gallino G

    更新日期:1993-12-01 00:00:00

  • [The possibility of inducing subcutaneous granulomas using plant foreign bodies. Experimental research].

    abstract::Experimental research designed to provoke subcutaneous granulomas by means of vegetable foreign bodies in animals is reported. The possibility of influencing the ongoing picture by means of anti-inflammatory drugs was also investigated. The findings were similar to those observed in a patient with a similar foreign bo...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Vizzini GM

    更新日期:1976-04-28 00:00:00

  • [Functional compromise of the small airways in subjects exposed to SiO2].

    abstract::Aims of our study were: to evaluate small airway function of subjects with past or present silica dust exposure and normal spirometric values; to investigate whether small airway disease is related to radiographic signs of silicosis, to cumulative dust exposure (ES) and to cigarette smoking. Maximal expiratory flow at...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Avolio G,Cacciabue M,Rolla G,Caria E,Oliaro A,Carlino F,Pepino E,Polizzi S,Bucca C

    更新日期:1986-11-30 00:00:00

  • COVID-19: a user's guide, status of the art, and an original proposal to terminate viral recurrence.

    abstract::The world is now entering its 9th month of combat against a pandemic of deadly pneumonia. Started out from China in December 2019, the disease has been declared as caused by infection with a so far unknown RNA Coronavirus of the respiratory family, then named severe acute respiratory syndrome coronavirus (SARS)-CoV-2....

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:10.23736/S0026-4806.20.07054-8

    authors: Actis GC,Ribaldone DG,Fagoonee S,Pellicano R

    更新日期:2020-10-26 00:00:00

  • [Evolution and radiologic sequelae of pulmonary tuberculosis].

    abstract::During the treatment of pulmonary tuberculosis, the radiologist is often asked the following questions: 1) is it really TB?; 2) is there any improvement?; 3) when is the X-ray check-up required?. In our opinion, the radiologist is in a position: 1) to confirm the diagnosis of TB; 2) to give a radiological diagnosis of...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Comino E,Ragni G,Trapani P,Camarrota T

    更新日期:1985-05-12 00:00:00

  • [Sex hormones, glycolipid metabolism, and atherogenesis].

    abstract::The prevalence of coronary artery disease is lower in women than in men. Ovarian estrogen is believed to decrease the risk of coronary heart disease. Today, there is an increasing demand for estrogen replacement not only for amelioration of menopausal subjective symptoms but also for the prophylactic action of estroge...

    journal_title:Minerva medica

    pub_type: 杂志文章,评审

    doi:

    authors: Sarubbi B,Ducceschi V,Russo B,Di Micco G,Iacono A

    更新日期:1995-06-01 00:00:00

  • [Epidemiological study on chronic bronchitis with special reference to various occupational environments in a sample of the population from the town of Pistoia].

    abstract::The results of an epidemiological study of chronic bronchitis are examined with particular regard to the influence of occupational environment on the disease. The damaging effect of organic and inorganic dusts, because of the irritation they cause and the possibility of allergic sensitization, is pointed out. The impo...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Palamidessi C

    更新日期:1977-03-24 00:00:00

  • Endoscopic mucosal resection-endoscopic submucosal dissection: do we really need endoscopic ultrasonography assistance?

    abstract::Endoscopic mucosal resection has become the standard of care for early gastrointestinal cancer. The application of this new treatment requires an accurate stadiation of the neoplasia. The exclusion of nodal involvement and the evaluation of the depth of tumor penetration within the gastrointestinal wall is essential t...

    journal_title:Minerva medica

    pub_type: 杂志文章,评审

    doi:

    authors: Repici A,Pagano N

    更新日期:2007-08-01 00:00:00

  • [Intrauterine torsion of the spermatic cord].

    abstract::Description of a clinical case diagnosed in the first hours of life in apparently well newborn. Diagnostic suspicion by palpation and transillumination. Absence of any subjective sign. Inspective symptom the light scrotal swelling. The neonate received an immediate surgical exploration with subsequent orchiectomy. ...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Galligani L,Ghiron P,Giudici M

    更新日期:1992-12-01 00:00:00

  • [Effectiveness of and tolerability to oral desmopressin in the treatment of central diabetes insipidus].

    abstract::Intranasal desmopressin represents the treatment of choice in Central Diabetes Insipidus. Nevertheless, this route of administration bears some practical disadvantage, linked to either difficult delivering technique, or the status of nasal mucose. The antidiuretic effectiveness of oral desmopressin has been recently d...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Merola B,Caruso E,De Chiara G,Rossi E,Longobardi S,Colao A,Brusco G,Lombardi G,Biraghi M

    更新日期:1992-12-01 00:00:00

  • [Idiopathic hypereosinophilic syndrome. Current clinico-therapeutic state].

    abstract::Idiopathic hypereosinophilic syndrome is a term labelling clinical illnesses characterized by blood hypereosinophilia and widespread infiltration of organs and tissues by mature eosinophils. Although any tissue can be affected the involvement of the nervous system and of the myocardium usually indicates worse prognosi...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Mercadanti M,Cavalieri F,Ferraccioli GF,Ambanelli U

    更新日期:1985-10-13 00:00:00

  • [Double-blind study of the bronchodilating action of the aminophylline-clenbuterol combination in asthmatic patients].

    abstract::The results obtained with the administration of aminophylline and clenbuterol either separately or in association, to a group of patients with chronic obstructive bronchopneumopathies are reported. The two drugs had a more or less identical broncho-dilatory effect with the beta 2-stimulant acting earlier but for a sho...

    journal_title:Minerva medica

    pub_type: 临床试验,杂志文章

    doi:

    authors: Osella D,Giorgis GE,Galietti F,Miravalle C,Ardizzi A

    更新日期:1986-04-21 00:00:00

  • [The value of the basophil degranulation test on the study of hypersensitivity reactions to iodinated contrast media].

    abstract::The ability of basophils and tissue mastocytes activated by sensitised IgE antibodies to release mediators in the presence of the specific antigen underlies immediate hypersensitivity reactions. This phenomenon can be explored by the in vitro basophil degranulation test adopted not only in experimental pathology, but ...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Stratta P,Camussi G,Porcellini G,Dogliani M,Bianchi SD,Vercellone A

    更新日期:1981-06-30 00:00:00

  • [New concepts in the prognosis of renal obstructions based on radiological examination data].

    abstract::The study deals with obstructed kidneys not visualizable by normal radiography. The various radiological techniques after endovenous urography are analysed as to what extent the data obtained enable the surgeon to choose between radical and conservative measures. The usefulness and limitations of i.v. urography with h...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Navarrette RV

    更新日期:1975-11-14 00:00:00

  • [A case of melanoderma erroneously considered to be addisonian].

    abstract::A case characterized by a dark pigmentation of the skin with an initial hypotension and a lung tuberculosis in the remote anamnesis is described. The skin pigment was formed by lipofuscin and emosiderin, but only the former was found in the liver biopsy. Anyway, the pigment was not melanine and the surrenalic function...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Bertello P,Ciocca Vasino MA,Ferrua F,Lalloni R,Di Cerbo M,Rietto GB

    更新日期:1979-02-04 00:00:00

  • [A left atrial myxoma. The clinical aspects].

    abstract::The paper describes a case of left atrial myxoma, which was unidentified for many years after the onset of symptoms, with emphasis on the necessity for instrumental investigations (particularly M-mode and two-dimensional echocardiography) in order to obtain an accurate and prompt diagnosis of these affections when the...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Tomassini B,Torta D,Bobba F,Albano T

    更新日期:1990-03-01 00:00:00

  • [Proteinuria in the aged].

    abstract::The Authors for a better knowledge of the senile kidney have studied the urinary proteins of a group of elderly people resident in a geriatric institute. For instance they have noted the percentage of proteinuria in the urine of 313 patients (M and F) with various pathology, making also an electrophoresis of the urina...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Guaita A,Casale G

    更新日期:1978-03-30 00:00:00

  • [Frequency of goiter and urinary iodine in the Peidmont school children. Data on iodine contents in some local food].

    abstract::The frequency of thyroid alterations was examined and dietary iodine intake was assessed via urinary iodine in 6-15 yr-old schoolchildren from 145 towns in Piedmont and the Aosta Valley. Local food iodine values were also determined in 56 towns. Alteration frequency and daily urinary elimination of iodine were inverse...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Costa A,Testori OB,Cenderelli G,Patrito G,Piazza A

    更新日期:1975-10-17 00:00:00

  • [Metabolic aspects of obesity].

    abstract::Classification of obesity in accordance with a new anatomical and functional criterion means that a hyperplastic and a hypertrophic form can be distinguished. The distinction is of both academic and practical significance, since different metabolic changes are observed in the two forms. Hyperplastic obesity appears ...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Muntoni S

    更新日期:1975-05-16 00:00:00

  • [Mechanisms of regulation of arterial blood pressure: role of the sympathetic nervous system and of the renin-angiotensin system in patients on a low-sodium diet].

    abstract::In order to discover more about the role of the sympathetic nervous and renin-angiotensin systems in the preservation of homeostasis during chronic reductions of salt intake, blood pressure, blood catecholamines and renin activity were measured in a group of healthy subjects in normal conditions and on a salt-free die...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Lembo G,Autiero C,Morganti A,Ricci A,Volpe M,Condorelli M

    更新日期:1987-12-15 00:00:00

  • [Ca 19-9 and Ca 50 in the diagnosis of bronchial carcinoma: comparison with CEA].

    abstract::The search for early tumour markers has brought to light CA 19-9 and CA 50, glycoproteins recognised by monoclonal antibodies. Since these markers are mainly used on the digestive tract it was thought useful to investigate their value in the diagnosis of lung cancer which is only rarely identified by markers in its ea...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Pecchio F,Rapellino M,Oliaro A,Moscato D,Adamo R,Albertino B,Lo Faso C,Faga C,Borasio P

    更新日期:1988-03-01 00:00:00

  • [Clinico-epidemiologic study of patients with phlebolymphatic diseases admitted to the hospitals of the Piedmont region 1976-1979. III. Analysis of varicose disease].

    abstract::With the aid of the University and Piedmont Region Computer Centre all cases of varicose admitted to Piedmontese hospitals between 1976 and 1979 were examined. One admission every 1 hour 35 minutes is the regional average. In terms of age there is a numerical prevalence (8526 cases) of the under forty-fives, while in ...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Raso AM,Levis P,Rispoli P,Carlin R

    更新日期:1983-06-16 00:00:00

  • Role of niacin in current clinical practice.

    abstract::Despite significant risk reduction with statin therapy, there remains a residual cardiovascular risk. It has been seen that aggressive statin therapy in high risk patients may not lower the low-density lipoprotein cholesterol to goal in up to 40% of patients. Niacin is a potent high-density lipoprotein cholesterol-rai...

    journal_title:Minerva medica

    pub_type: 杂志文章,评审

    doi:10.23736/S0026-4806.18.05826-3

    authors: Sharma A,Madan N

    更新日期:2019-02-01 00:00:00

  • Use of fractional flow reserve in contemporary scenarios of coronary revascularization.

    abstract::Fractional flow reserve (FFR), an invasive pressure-derived index of stenosis severity, can be performed easily, rapidly, and safely in patients with coronary artery disease as a surrogate of non-invasive detection of ischemia. Over the last decades, profound clinical and scientific evaluation has demonstrated that FF...

    journal_title:Minerva medica

    pub_type: 杂志文章,评审

    doi:

    authors: Echavarría-Pinto M,Escaned J

    更新日期:2011-10-01 00:00:00

  • Efficacy comparison of glutaraldehyde-phenate vs other glutaraldehydes in fomites disinfection, by different methods.

    abstract:OBJECTIVE:To compare the efficacy of glutaraldehyde-phenate against four other glutaraldehydes. DESIGN:We use two methods: (1) Bacteriostatic method- With 97 microrganisms of 8 different species. (2) Bactericide method- With a low contamination (10(4)cfu) plus organic soil (simulating the work conditions of glutaralde...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Herruzo-Cabrera R,Gil-Miguel A,Fernandez-Arjona M,Rey-Calero J

    更新日期:1994-11-01 00:00:00

  • [Slow cerebral potentials after administration of flunitrazepam to subjects with sleep disorders].

    abstract::12 patients admitted for neurological diseases and suffering from sleep disturbances, were given Flunitrazepam and placebo (double blind test) in a single evening dose of 1 and 2 mg. Morning recordings of the expectation wave according to G. Walter's technique did not reveal significant changes in wave morphology, amp...

    journal_title:Minerva medica

    pub_type: 临床试验,杂志文章

    doi:

    authors: Rizzo PA,Caporali M,Spadaro M,Zanasi M

    更新日期:1980-02-25 00:00:00