Abstract：
:Fractional flow reserve (FFR), an invasive pressure-derived index of stenosis severity, can be performed easily, rapidly, and safely in patients with coronary artery disease as a surrogate of non-invasive detection of ischemia. Over the last decades, profound clinical and scientific evaluation has demonstrated that FFR is one of the few diagnostic modalities that improve patient outcome and, at the same time, are cost-effective and cost-saving. The increasing use of PCI to treat multivessel disease and complex anatomical subsets has created new demands for accurate, "per stenosis" assessment, since revascularisation should be performed only in those stenosis that are ischaemia generating. Recent studies have demonstrated that this attitude results in better patient outcomes. Altogether, current evidence clearly supports the measurement of FFR in catheterization laboratories in order to provide objective and complementary data to coronary angiography. The purpose of this review is to discuss the value of FFR in the diagnosis and treatment of patients with different anatomical subsets, including intermediate stenosis, multivessel disease, left main disease, serial stenosis, ostial and bifurcation lesions, saphenous vein graft disease and in-stent restenosis, as well as in those presenting with acute coronary syndromes.
journal_name
Minerva Medjournal_title
Minerva medicaauthors
Echavarría-Pinto M,Escaned Jsubject
Has Abstractpub_date
2011-10-01 00:00:00pages
399-415issue
5eissn
0026-4806issn
1827-1669pii
R10113257journal_volume
102pub_type
杂志文章,评审相关文献
MINERVA MEDICA文献大全abstract：:Malignant tumours mortality among residents of the city of Verona (267,703 at 31-12-1980) during the year 1980 is assessed from the ISTAT individual death cards and/or municipal death certificates (especially in the case of deaths outside the municipality). The figures are broken down by site, apparatus or system (in ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1983-11-16 00:00:00
abstract：:A case characterized by a dark pigmentation of the skin with an initial hypotension and a lung tuberculosis in the remote anamnesis is described. The skin pigment was formed by lipofuscin and emosiderin, but only the former was found in the liver biopsy. Anyway, the pigment was not melanine and the surrenalic function...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1979-02-04 00:00:00
abstract：:12 patients admitted for neurological diseases and suffering from sleep disturbances, were given Flunitrazepam and placebo (double blind test) in a single evening dose of 1 and 2 mg. Morning recordings of the expectation wave according to G. Walter's technique did not reveal significant changes in wave morphology, amp...
journal_title：Minerva medica
pub_type： 临床试验,杂志文章
doi：
更新日期：1980-02-25 00:00:00
abstract：:Clinical history and morbid anatomy findings of a new case of ataxia-telangiectasia are reported. A 26 years old man, with overt signs of the disease since the age of 8, died for decompensated cirrhosis; in the last year he suffered for cerebral haemorrhage; post-mortem examination showed venous angiectasias in cerebr...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1982-09-08 00:00:00
abstract：:The paper describes a case of left atrial myxoma, which was unidentified for many years after the onset of symptoms, with emphasis on the necessity for instrumental investigations (particularly M-mode and two-dimensional echocardiography) in order to obtain an accurate and prompt diagnosis of these affections when the...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1990-03-01 00:00:00
abstract：:Gastric abnormalities are more common in diabetics than in the normal population. They seem to be related to gastric parietal cell autoantibodies (GPCA). We have studied 168 patients affected with non-insulin-dependent diabetes mellitus (NIDDM), and assessed the GPCA in the serum and haematologic disorders. We have al...
journal_title：Minerva medica
pub_type： 临床试验,杂志文章
doi：
更新日期：1992-10-01 00:00:00
abstract：:The Monfalcone area (Italy) is a small industrial territory (60,000 inhabitants), characterized by a high incidence of asbestos-related diseases. In a review of the biopsy and necropsy records collected at the Monfalcone Hospital during the period October 1979-September 1985 two cases of Kaposi's sarcoma were found. O...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1986-06-23 00:00:00
abstract：:Although a peripheral neuropathy is the best known neurological complication of Waldenstrom's Macroglobulinemia (WM), the association of Amyotrophic Lateral Sclerosis (ALS), or other Motor Neuron Diseases (MND) with monoclonal gammopathies is described. We report the case of a male patient (41 years old) with WM and A...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1997-04-01 00:00:00
abstract：:The main points in the history of Australia antigen in the ten years since its discovery are summarised. Reference is made to an epidemic episode observed in a community in discussing a number of aetiopathogenetic and nosological features recently codified by official infectivology. ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1975-10-13 00:00:00
abstract：:Serum levels of carcinoembryonic antigen (CEA) and tissue polypeptide antigen (TPA) were investigated in 53 lung cancer patients. The higher percentage of patients with serum CEA positivity was observed within the anaplastic lung cancer group. TPA serum positivity was found in similar percentage in all the examined gr...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1986-03-17 00:00:00
abstract：:18 cases of anatomically verified lung cancer were studied scintigraphically with microspheres of human albumin labelled with 99Tc, mercury bichloride (197Hg) and citrate of gallium (67Ga), to assess the diagnostic value of this technique. Using albumin microspheres, changes in the scintigraphic picture were obtained ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1976-10-27 00:00:00
abstract：:The Authors have studied the evolution of the cleft palate's surgery, illness known from ancient times, but without any therapeutic solution for a long time. After the discovery of America, with the presence of a new syphilitic infection, cleft palate was generally considered as a consequence of syphilis, and undoubte...
journal_title：Minerva medica
pub_type： 历史文章,杂志文章
doi：
更新日期：1983-01-14 00:00:00
abstract：:Epidemiology of muscular dystrophies has been important in the prevention of these diseases. In fact the genetic counselling, after a preliminary epidemiological investigation, reduced the incidence rate of Duchenne muscular dystrophy in the Veneto Region. Furthermore the new biochemical data on dismetabolic muscular ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1981-04-28 00:00:00
abstract：:Personal experience with acute enzymatic pancreatitis in 113 cases observed, over 11 years, at the Santa Croce Hospital Surgical Division is described. Only 58 cases (51,3%) were submitted to surgery and the remaining 55 cases (48,7%) were treated with medical therapy. A mortality of 16,8% was observed. ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1977-05-05 00:00:00
abstract：:Angiograms obtained before and after acupuncture in a small series of patients with Raynaud's disease did not give positive evidence of its therapeutic effect. A marked vasodilatatory action was noted, however, suggesting that the technique can be usefully applied along with other forms of management. ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1977-03-03 00:00:00
abstract：:Digestive endoscopy represents the current therapy of the gastric polyps. These lesions are endoscopically found in an unexpected number of patients, because of the frequent failure of radiology by itself. Furthermore endoscopic radical polypectomy is mostly possible for the inflammatory and adenomatous polyps. Otherw...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1981-01-28 00:00:00
abstract：:Obstructive sleep apnea syndrome (OSAS) is characterized by repeated oropharyngeal occlusions occurring during sleep. The prevalence of moderate OSAS (with an apnea-hypopnea index = or >15/h) is 9% and 4% in male and female, respectively. It is associated with an abnormally high frequency of cardiovascular disease (hy...
journal_title：Minerva medica
pub_type： 杂志文章,评审
doi：
更新日期：2004-06-01 00:00:00
abstract：INTRODUCTION:Endoscopic ultrasound-guided (EUS) biliary drainage was used as an alternative method for patients who failed endoscopic retrograde cholangiopancreatography (ERCP). In recent years, an increasing number of patients was treated with EUS-biliary drainage (BD), but lack of data was available to value the effi...
journal_title：Minerva medica
pub_type： 杂志文章,meta分析
doi：10.23736/S0026-4806.19.05981-0
更新日期：2019-12-01 00:00:00
abstract：:12 patients with normal QRS either in basal condition or during atrial pacing, undergone on single premature atrial stimulation, showed several types of intraventricular aberrancies. These have been revalued with atrial premature stimulation introduced over a progressively increasing frequency of fixed atrial stimulat...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1978-03-24 00:00:00
abstract：:The authors examine the clinical connotations of arterial hypertension in a geographical population of 1002 patients attending the Cardiological Outpatient Clinic of Unit no.2 in the Isonzo area (Monfalcone) using the most appropriate statistical methods, such as SPSS (Statistical Package for the Social Sciences) impl...
journal_title：Minerva medica
pub_type： 杂志文章,评审
doi：
更新日期：1996-09-01 00:00:00
abstract：:The results of preliminary research designed to prepare a method for using mouth measurements to identify alveolar air trapping phenomena which cannot be detected by normal techniques are reported. With a present rapid thermoconductivity CO2/He analyser, it was shown that even after the completion of a standard He was...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1977-03-31 00:00:00
abstract：:Current estimates of the prevalence of chronic pancreatitis, one of the most common causes of exocrine pancreatic insufficiency, are in the range of 3-10 per 100,000 people in many parts of the world. Alcohol consumption is a very important risk factor for exocrine pancreatic insufficiency and is involved in nearly ha...
journal_title：Minerva medica
pub_type： 杂志文章,评审
doi：10.23736/S0026-4806.19.06043-9
更新日期：2019-10-01 00:00:00
abstract：:A group of heart patients and another group of healthy subjects have been studied and their systolic intervals (PEP-LVET - PEP/LVET ratio and the telediastolic index) evaluated using the mechanocardiographic system. In both long-standing and recent heart patients, the parameters studied showed significant deviations f...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1982-09-15 00:00:00
abstract：:The results obtained in a single blind controlled study using a new preparation, guacetisal, and an already available similar product based on dimethylaminophenazone guaiacolglycolate and calcium ethylcamphorate, are reported. The drugs were administered to 28 elderly patients of both sexes suffering from bronchopneum...
journal_title：Minerva medica
pub_type： 临床试验,杂志文章
doi：
更新日期：1981-02-28 00:00:00
abstract：:Several issues concerning the biocompatibility) testing of medical devices as stated in European directive 90/385 and 93/42 are discussed. The authors describe the fundamental characteristics that biomaterials should have to be employed in the human body, the assays useful for testing different aspects of biocompatibi...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1995-10-01 00:00:00
abstract：:A case of dyslipoproteinaemia of type V in a woman suffering from primary hypothyroidism, florid diabetes mellitus and obesity is reported. The case is commented on in general and as regards possible correlations between the diseases and the dyslipoproteinaemic picture. The various therapeutic treatment employed and r...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1976-07-21 00:00:00
abstract：:A review of existent epidemiological data on subarachnoid hemorrhage is reported. The average annual incidence rate per 100,000 ranges from 7.4 to 19.4. The relative frequency in confront of all types of stroke ranges from 3 to 11%. The most important risk factors are: age over 40, feminine sex, arterial blood hyperte...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1986-06-08 00:00:00
abstract：:This is the first epidemiological study of Hepatocellular Carcinoma (HCC) in the province of Bergamo, an area well-known to have a high incidence of HBsAg (9.1%) and chronic alcoholic liver disease. 72 cases of HCC (60 male, 12 female) al from the province of Bergamo and encountered in 1980-84 were subjected to an epi...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1986-03-10 00:00:00
abstract：INTRODUCTION:The aim of this study was to determine the role of Prognostic Nutritional Index in predicting gastric cancer. EVIDENCE ACQUISITION:Studies were searched in PubMed, EMBASE and ISI Web of Science. The hazard ratios and 95% confidence interval for survival estimate were extracted from the articles and the po...
journal_title：Minerva medica
pub_type： 杂志文章,meta分析
doi：
更新日期：2016-10-01 00:00:00
abstract：:Personal experience of pacemakers in patients suffering from (symptomatic and asymptomatic) 2nd degree AVB and 3rd degree AVB is reported. ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
