Abstract：
:Classification of obesity in accordance with a new anatomical and functional criterion means that a hyperplastic and a hypertrophic form can be distinguished. The distinction is of both academic and practical significance, since different metabolic changes are observed in the two forms. Hyperplastic obesity appears early in life and is particularly intractable. It is not usually accompanied by dysmetabolic signs, however. Hypertrophic obesity, on the other hand, is accompanied by endocrine and metabolic alterations, marked by insulin resistance, sugar intolerance, hyperinsulinaemia, hypertriglyceridaemia, and hyperuricaemia. Recent data are cited for the proposition that these changes constitute a closed pathogenetic concatenation creating a vicious circle. Fatty acids play a particularly important part in this context, since they are synthetized, released, presented and oxidated to a pathological degree.
journal_name
Minerva Medjournal_title
Minerva medicaauthors
Muntoni Skeywords:
subject
Has Abstractpub_date
1975-05-16 00:00:00pages
1741-7issue
37eissn
0026-4806issn
1827-1669journal_volume
66pub_type
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