Schmorl Nodes Can Cause Increased 68Ga DOTATATE Activity on PET/CT, Mimicking Metastasis in Patients With Neuroendocrine Malignancy.

Abstract:

:Schmorl node (SN) is the herniation of the nucleus pulposus through the cartilaginous and bony endplate into the adjacent vertebral body. It is documented that SNs produce areas of moderately increased F-FDG uptake. We present a case of a patient with history of neuroendocrine tumor, who underwent Ga DOTATATE PET/CT for follow-up, showing increased focal vertebral uptake suggestive of bone metastasis. CT revealed typical findings of an SN. The presented case indicates that SNs should be considered when encountering focally increased skeletal uptake in Ga DOTATATE PET/CT studies, which can mimic metastasis in patients with history of neuroendocrine tumors.

journal_name

Clin Nucl Med

authors

Papadakis GZ,Millo C,Bagci U,Sadowski SM,Stratakis CA

doi

10.1097/RLU.0000000000001065

subject

Has Abstract

pub_date

2016-03-01 00:00:00

pages

249-50

issue

3

eissn

0363-9762

issn

1536-0229

journal_volume

41

pub_type

杂志文章
  • Analysis of the roles of glucose transporter 1 and hexokinase 2 in the metabolism of glucose by extrahepatic bile duct cancer cells.

    abstract:PURPOSE OF THE REPORT:Extrahepatic bile duct (EHD) cancer varies in uptake of FDG. The aim of the present study was to determine the role of glucose transporter (GLUT) 1 and hexokinase (HK) 2 in the glucose metabolism of EHD cancer cells using immunohistochemistry and 18F-FDG PET/CT. METHODS:Twenty-six patients with E...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000000640

    authors: Yoon SO,Jeon TJ,Park JS,Ryu YH,Lee JH,Yoo JS,Kim JK,Yoon DS,Oh EJ

    更新日期:2015-03-01 00:00:00

  • The value of urine creatinine analysis in the evaluation on Schilling tests.

    abstract::We performed a prospective study to assess the clinical value of evaluating the adequacy of 24-hour urine specimens submitted for Schilling tests. A total of 121 specimens were evaluated of which 51 had abnormal vitamin B12 excretion values. Of those 51, there were 23 with apparently inadequate total creatinine conten...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199003000-00010

    authors: Heironimus JD,Borchert RD,Weiland FL

    更新日期:1990-03-01 00:00:00

  • Tc-99m isonitrile uptake in a brain metastatic lesion. Comparison with Tc-99m DTPA using planar and SPECT imaging.

    abstract::Tc-99m isonitrile uptake in a metastatic brain tumor is demonstrated using planar and SPECT imaging. Comparison with Tc-99m DTPA shows a different distribution pattern and uptake intensity, suggesting a different mechanism for both tracers. It is possible that Tc-99m CPI could reflect metabolic activity of the tumor c...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199302000-00013

    authors: Mut F,Bianco A,Nuñez M,De Palma G,Touya E

    更新日期:1993-02-01 00:00:00

  • Lung cancer with solitary bone metastasis in the radius.

    abstract::We present a 73-year-old man with a new diagnosis of right upper lung adenocarcinoma. Right elbow x-ray and Tc-99m MDP whole body bone scan were performed due to a reddish, swollen, and painful right forearm for 1 week. X-ray, performed on March 25, 2008, showed an osteolytic lesion in the proximal right radius with s...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0b013e3181b53a21

    authors: Chun-Yi L,Yiing-Feng H,Hua-Tzu H,Chang-Sheng L

    更新日期:2009-10-01 00:00:00

  • Erythema nodosum associated with diffuse, large B-cell non-Hodgkin lymphoma detected by FDG PET.

    abstract::A patient is described with non-Hodgkin lymphoma and erythematous skin nodules suspected to be erythema nodosum. The patient underwent serial fluorodeoxyglucose (FDG) positron emission tomography (PET), which demonstrated normalization of FDG uptake by the lymphoma after 2 cycles of chemotherapy, but there was new abn...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/01.RLU.0000079389.14140.be

    authors: Cheong KA,Rodgers NG,Kirkwood ID

    更新日期:2003-08-01 00:00:00

  • Differential diagnosis of idiopathic fibrosis from malignant lymphadenopathy with PET and F-18 fluorodeoxyglucose.

    abstract::Idiopathic fibrosis and malignant lymphoma were studied with positron emission tomography (PET) using 2-deoxy-2-[F-18]fluoro-D-glucose (F-18DG). Cases of retroperitoneal fibrosis and sclerosing peritonitis showed low F-18DG uptake with the mass/muscle radioactivity (M/M) ratio 2.0 and 1.9, respectively. A case of para...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199205000-00002

    authors: Kubota K,Yamada K,Yoshioka S,Yamada S,Ito M,Ido T

    更新日期:1992-05-01 00:00:00

  • Radionuclide imaging and echography of thyroid nodules.

    abstract::The usefulness of grey scale ultrasonography in association with radionuclide imaging in the evaluation of thyroid nodules is discussed. Nodules were classified in five categories, according to the magnitude of the internal echoes (echogenicity). The assessment of neoplasms in each of these categories is reported in 1...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-197907000-00001

    authors: Espinasse P,Espinasse D

    更新日期:1979-07-01 00:00:00

  • Unusual liver variant mimicking a retroperitoneal mass. CT scan appearance and diagnosis by SPECT imaging.

    abstract::An unusual posterior extension of the right lobe of the liver mimicked a retroperitoneal mass on CT scanning. Tc-99m SC SPECT imaging documented normal liver uptake within the suspected mass, proving that it was an anomalous extension of the right lobe of the liver rather than a pathologic lesion. This unusual liver v...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199008000-00008

    authors: Karlins NL,Marmolya G,Miron S

    更新日期:1990-08-01 00:00:00

  • Thyroid dysfunction during interferon alpha therapy for chronic hepatitis C.

    abstract::Interferon-alpha therapy is well known to induce a wide range of thyroid dysfunction. A 22-year-old woman with chronic hepatitis C developed overt hyperthyroidism while on interferon-alpha and ribavirin therapy. Tc-99m thyroid scintigraphy demonstrated virtually absent tracer uptake consistent with subacute thyroiditi...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/01.rlu.0000170014.35693.6c

    authors: Shen L,Bui C,Mansberg R,Nguyen D,Alam-Fotias S

    更新日期:2005-08-01 00:00:00

  • F-18 FDG PET/CT imaging of bulky myxofibrosarcoma in chest wall.

    abstract::Myxofibrosarcoma (MFS) has a spectrum of malignant fibroblastic lesions with variably myxoid stroma and pleomorphism. A 67-year-old man with a bulky mass on his chest wall was diagnosed with MFS. He underwent F-18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography for detection of metastasis. FD...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0b013e318208f2e0

    authors: Ito K,Masuda-Miyata Y,Wada S,Morooka M,Yamasawa K,Hashimoto M,Kubota K

    更新日期:2011-03-01 00:00:00

  • SPECT in the management of patients with back pain and spondylolysis.

    abstract:PURPOSE:Single photon emission computed tomography (SPECT) bone scans of the lumbar spine were evaluated in the management of patients with low back pain and suspected spondylolysis. MATERIALS AND METHODS:Thirty-three patients (mean age, 30 years) with high clinical suspicion of pars interarticularis defects were incl...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-200002000-00001

    authors: Dutton JA,Hughes SP,Peters AM

    更新日期:2000-02-01 00:00:00

  • Characterization of Diffuse Gliomas With Histone H3-G34 Mutation by MRI and Dynamic 18F-FET PET.

    abstract:BACKGROUND:Recent data suggest that diffuse gliomas carrying mutations in codon 34 of the H3 histone family 3A protein represent a very rare, distinct subgroup of IDH-wild type malignant astrocytic gliomas. However, characteristics detectable by MRI and F-FET PET in H3-G34-mutant gliomas are unknown. METHODS:We report...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000002300

    authors: Vettermann FJ,Felsberg J,Reifenberger G,Hasselblatt M,Forbrig R,Berding G,la Fougère C,Galldiks N,Schittenhelm J,Weis J,Albert NL,Schüller U

    更新日期:2018-12-01 00:00:00

  • 18F-FDG PET/CT Features of Chronic Sclerosing Sialadenitis Presenting as Localized IgG4-Related Disease.

    abstract::Chronic sclerosing sialadenitis is a benign inflammatory condition that most commonly affects the submandibular gland in elderly individuals. It is currently known to belong to the spectrum of IgG4-related systemic diseases, which is reflected by systemic involvement on F-FDG PET/CT images. We presented a case of a 73...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000001482

    authors: Kashiwagi N,Enoki E,Hosokawa C,Sakaguchi K,Murakami T

    更新日期:2017-02-01 00:00:00

  • Delayed 68Ga-PSMA PET/CT Image-Guided Biopsy for Low-Grade Adenocarcinoma in Benign Prostatic Hyperplasia.

    abstract::Image-guided biopsy of prostate with multiparametric MRI is being adopted in the workup of prostate adenocarcinoma (PAC). Ga-PSMA PET/CT-guided biopsy has also been shown to be equally sensitive in the evaluation of higher-grade tumors with increased PSMA expression. The sensitivity of Ga-PSMA PET/CT, however, reduces...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000003440

    authors: Santhosh S,Jeeva G

    更新日期:2020-11-23 00:00:00

  • Gamma probe-guided resection of a lymph node metastasis with I-123 in papillary thyroid carcinoma.

    abstract::The authors report the case of a 27-year-old woman with gamma probe-guided resection of a recurrent regional lymph node metastasis in papillary thyroid cancer. Reoperation is often impaired in cases with extensive scarring because of previous surgery, high-dose radioiodine therapy, and external irradiation. In this ca...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199709000-00002

    authors: Gallowitsch HJ,Fellinger J,Mikosch P,Kresnik E,Lind P

    更新日期:1997-09-01 00:00:00

  • Staging lung carcinoma with a Tc-99m labeled monoclonal antibody.

    abstract::Thirty-three patients with biopsy-proven lung cancer and a total of 150 lesions diagnosed by conventional staging procedures were imaged using a Tc-99m labeled monoclonal Fab fragment of an IgG2B murine monoclonal antibody (MoAb) (NR-LU-10, NeoRx Corporation). Immunoscintigraphy demonstrated 100% of primary and 78% of...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199206000-00001

    authors: Vansant JP,Johnson DH,O'Donnell DM,Stewart JR,Sonin AH,McCook BM,Powers TA,Salk DJ,Frist WH,Sandler MP

    更新日期:1992-06-01 00:00:00

  • Incidence of second primary malignancies during a long-term surveillance of patients with differentiated thyroid carcinoma in relation to radioiodine treatment.

    abstract:PURPOSE:Controversies remain over the actual risk of developing a second primary malignancy (SPM) as a consequence of I-131 treatment in patients with differentiated thyroid carcinoma (DTC). The objective of this study was to evaluate the adjusted rate and risk estimate of SPM in radioiodine-treated patients after cont...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0b013e31820a9fe3

    authors: Fallahi B,Adabi K,Majidi M,Fard-Esfahani A,Heshmat R,Larijani B,Haghpanah V

    更新日期:2011-04-01 00:00:00

  • Metastatic female adnexal tumor of possible wolffian origin (FATWO) of the appendix demonstrated by FDG PET/CT: the first reported case.

    abstract::Both female adnexal tumor of possible wolffian origin (FATWO) and metastasis to the appendix from any primary tumor are extremely rare entities. The appendiceal metastasis from FATWO has not been reported, and there is a lack of the literature regarding FDG PET/CT study in both. We reported the case of an appendiceal ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0b013e318203bc77

    authors: Liu Y

    更新日期:2011-02-01 00:00:00

  • Relationship between myocardial perfusion-gated SPECT and the performance of coronary revascularization in patients with ischemic cardiomyopathy.

    abstract:PURPOSE:Ischemic cardiomyopathy (ICM) is a disease with high morbidity and mortality. There are several published studies on the evolution and prognosis of patients with ICM. However, reports on the therapeutic management in clinical practice are scarce. The aim of this study was to analyze coronary revascularization (...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0b013e318263907b

    authors: Romero-Farina G,Candell-Riera J,Aguadé-Bruix S,Ferreira-Gonzalez I,Igual A,García-Dorado D

    更新日期:2012-10-01 00:00:00

  • Isolated Multinodular Soft-Tissue Rosai-Dorfman Disease on FDG PET/CT.

    abstract::Rosai-Dorfman disease (sinus histiocytosis with massive lymphadenopathy) is a rare systemic histiocytic disorder of unknown etiology characterized by the accumulation of enlarged non-Langerhans histiocytes within lymph nodes and extranodal sites. The histiocytes display characteristic emperipolesis (nondestructive eng...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000001921

    authors: Pucar D,Laskin WB,Saperstein L

    更新日期:2018-02-01 00:00:00

  • Unusual pattern of lung uptake of technetium-99m sulfur colloid seen on the liver scan of a patient with pulmonary tuberculosis.

    abstract::In evaluating alcoholic liver disease in a patient with pulmonary tuberculosis, a liver-spleen scan was performed that showed an unusual uptake of sulfur colloid in the lungs. There was diffuse uptake in the left lung and portions of the right lower lung with absent uptake in the right upper lobe and portions of the r...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-198904000-00007

    authors: Stewart CA,Hung GL,Siegel ME,McHutchison JG

    更新日期:1989-04-01 00:00:00

  • Is PET/CT Necessary in the Management of Early Breast Cancer?

    abstract:PURPOSE:Advanced imaging methods in early breast cancers are not recommended before surgery. In contrast to the accepted guidelines, some recent studies have shown some benefits with the use of PET/CT in early-stage breast cancer. In this study, we aimed to document the efficacy of PET/CT in detection of distant metast...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000001165

    authors: Nursal GN,Nursal TZ,Aytac HO,Hasbay B,Torun N,Reyhan M,Yapar AF

    更新日期:2016-05-01 00:00:00

  • Diagnosis of dementia using perfusion SPECT imaging at the patient's initial visit to a cognitive disorder clinic.

    abstract:PURPOSE:This study was performed to evaluate the diagnostic accuracy of brain perfusion SPECT in patients visiting the cognitive disorder clinic for initial evaluation using 3D-SSP compared with using standard transaxial section. MATERIALS AND METHODS:Standard transaxial section displays and 3D-SSP z-score maps obtain...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/01.rlu.0000246818.24566.54

    authors: Uchida Y,Minoshima S,Okada S,Kawata T,Ito H

    更新日期:2006-12-01 00:00:00

  • Management of thyroid papillary carcinoma with radioiodine in a patient with end stage renal disease on hemodialysis.

    abstract::Metastatic papillary carcinoma was diagnosed in a 42-year-old woman. The cancer had invaded out of the gland and was present in many lymph nodes. After her surgical procedure, she was advised to have radioiodine. However, the patient had total renal failure and was on dialysis. Studies were carried out using a tracer ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199409000-00006

    authors: Mello AM,Isaacs R,Petersen J,Kronenberger S,McDougall IR

    更新日期:1994-09-01 00:00:00

  • 18F-Fluciclovine-Avid Mediastinal Lymph Node Metastasis of Cutaneous Malignant Melanoma.

    abstract:ABSTRACT:A 63-year-old man with recent diagnosis of high-risk prostate adenocarcinoma was referred to our Nuclear Medicine Department for 18F-fluciclovine PET/CT to rule out metastasis in the setting of elevated serum prostate-specific antigen levels. The patient had previous history of nodular melanoma of the right ch...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000003319

    authors: Shariftabrizi A,Pillenahalli Maheshwarappa R,Kahn D,Pollard J

    更新日期:2021-02-01 00:00:00

  • F-18 FDG PET/CT as a crucial guide toward optimal treatment planning in a case of postirradiation sarcoma 10 years after primary bone lymphoma of the pelvis.

    abstract::Ten years after chemoradiation for primary lymphoma of the left pelvic bone, a 38-year-old man presented with a 4-month history of gradually increasing pain in his left upper leg and thigh. Initial radiographs and contrast-enhanced magnetic resonance imaging were consistent with recurrent lymphoma, infection, or posti...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0b013e318217561c

    authors: de Rooy JW,Hambrock T,Vriens D,Flucke UE,van der Geest IC,van de Luijtgaarden AC,Schreuder BW,de Geus-Oei LF

    更新日期:2011-07-01 00:00:00

  • Methionine PET Might Be Reliable for the Detection of Low M-Protein-Producing Myelomas.

    abstract::C-methionine (MET) positron emission tomography (PET) is more sensitive than F-fluorodeoxyglucose (FDG)-PET for detecting myeloma lesion. Many clinical studies support this evidence mainly for multiple myeloma cases of IgG or IgA subtypes. However, this is not confirmed for low monoclonal protein-producing myelomas, s...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000001821

    authors: Imataki O,Uchida S,Yokokura S,Uemura M,Kadowaki N

    更新日期:2017-11-01 00:00:00

  • Indium-111 leukocyte localization in infected prosthetic graft.

    abstract::Infective endocarditis can be difficult to prove, even in the face of strong clinical suspicion. A case in which standard methods of diagnosis failed to demonstrate endocarditis in a patient with recurrent Staphylococcus aureus bacteremia and porcine aortic valve is reported. An In-111 labelled leukocyte SPECT study d...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199008000-00020

    authors: Purnell GL,Walker CW,Allison JW,Dalrymple GV

    更新日期:1990-08-01 00:00:00

  • The potential use of I-123 IMP scintigraphy for pelvic bone metastases in hepatocellular carcinoma. A comparison with Ga-67 scintigraphy.

    abstract::Conventional bone scintigraphy is often inconclusive in detecting bone metastases of hepatocellular carcinoma, suggesting the necessity of alternative scintigraphic agents. In this study, the diagnostic value of I-123 IMP scintigraphy was evaluated in 8 patients with 12 pelvic bone metastases from hepatocellular carci...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199404000-00005

    authors: Suto Y,Tanigawa N,Iwamiya T,Shabana M,Ohta Y

    更新日期:1994-04-01 00:00:00

  • Transient false-positive hepatobiliary scan associated with ceftriaxone therapy.

    abstract::Drug related false-positive hepatobiliary imaging is uncommon. The authors present a case of a 54-year-old woman who was treated with intravenous ceftriaxone for bacterial meningitis. Symptoms of acute cholecystitis subsequently developed and a sonogram revealed a gallstone. A Tc-99m DISIDA hepatobiliary study was pos...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199601000-00002

    authors: Lorberboym M,Machado M,Glajchen N,Pertsemlidis D

    更新日期:1996-01-01 00:00:00