Folic acid protects against arsenic-mediated embryo toxicity by up-regulating the expression of Dvr1.

abstract：:A polarized macrophage response into inflammatory (M1) or regenerative/anti-inflammatory (M2) phenotypes is critical in host response to multiple intracellular bacterial infections. Ehrlichia is an obligate Gram-negative intracellular bacterium that causes human monocytic ehrlichiosis (HME): a febrile illness that may...

journal_title：Scientific reports

authors： Haloul M,Oliveira ERA,Kader M,Wells JZ,Tominello TR,El Andaloussi A,Yates CC,Ismail N

更新日期：2019-10-01 00:00:00

abstract：:C4.4A is a modular glycolipid-anchored Ly6/uPAR/α-neurotoxin multidomain protein that exhibits a prominent membrane-associated expression in stratified squamous epithelia. C4.4A is also expressed in various solid cancer lesions, where high expression levels often are correlated to poor prognosis. Circumstantial eviden...

journal_title：Scientific reports

authors： Kriegbaum MC,Jacobsen B,Füchtbauer A,Hansen GH,Christensen IJ,Rundsten CF,Persson M,Engelholm LH,Madsen AN,Di Meo I,Lund IK,Holst B,Kjaer A,Lærum OD,Füchtbauer EM,Ploug M

更新日期：2016-05-12 00:00:00

abstract：:Air pollution has been classified as a group 1 carcinogen in humans, but the underlying tumourigenic mechanisms remain unclear. In Xuanwei city of Yunnan Province, the lung cancer incidence is among the highest in China, owing to severe air pollution generated by the combustion of smoky coal, providing a unique opport...

journal_title：Scientific reports

authors： Pan HL,Wen ZS,Huang YC,Cheng X,Wang GZ,Zhou YC,Wang ZY,Guo YQ,Cao Y,Zhou GB

更新日期：2015-09-23 00:00:00

abstract：:In the last 40 years only one new antitubercular drug has been approved, whilst resistance to current drugs, including rifampicin, is spreading. Here, we used the model organism Mycobacterium smegmatis to study mechanisms of phenotypic mycobacterial resistance, employing quantitative mass spectrometry-based proteomics...

journal_title：Scientific reports

authors： Giddey AD,de Kock E,Nakedi KC,Garnett S,Nel AJ,Soares NC,Blackburn JM

更新日期：2017-03-06 00:00:00

abstract：:Some herbivore-induced-plant volatiles (HIPVs) compounds are vital for the functioning of an ecosystem, by triggering multi-trophic interactions for natural enemies, plants and herbivores. However, the effect of these chemicals, which play a crucial role in regulating the multi-trophic interactions between plant-herbi...

journal_title：Scientific reports

authors： Lin Y,Qasim M,Hussain M,Akutse KS,Avery PB,Dash CK,Wang L

更新日期：2017-01-12 00:00:00

abstract：:Fruit firmness is an important market driven trait in sweet cherry (Prunus avium L.) where the desirable increase in fruit firmness is associated with landrace and bred cultivars. The aim of this work was to investigate the genetic basis of fruit firmness using plant materials that include wild cherry (syn. mazzard), ...

journal_title：Scientific reports

authors： Cai L,Quero-García J,Barreneche T,Dirlewanger E,Saski C,Iezzoni A

更新日期：2019-03-21 00:00:00

abstract：:Attraction to infants is a common feature of non-human primates. Frequent affiliative male-infant interactions have been observed in many multimale, multifemale groups of macaques, including a behaviour termed 'bridging' in which two male macaques simultaneously lift an infant. This behaviour has been suggested to ser...

journal_title：Scientific reports

authors： Zhang D,Xia DP,Wang X,Zhang QX,Sun BH,Li JH

更新日期：2018-11-02 00:00:00

abstract：:Genetic polymorphisms in drug metabolizing enzymes and drug transporters may affect irinotecan toxicity. Although genetic polymorphisms have been shown to influence the irinotecan toxicity, data are limited in Thai population. Thus, the aim of this study was to assess the allele and genotype frequencies and the relati...

journal_title：Scientific reports

authors： Atasilp C,Chansriwong P,Sirachainan E,Reungwetwattana T,Sirilerttrakul S,Chamnanphon M,Puangpetch A,Sukasem C

更新日期：2020-08-10 00:00:00

abstract：:Coenzyme engineering that changes NAD(P) selectivity of redox enzymes is an important tool in metabolic engineering, synthetic biology, and biocatalysis. Here we developed a high throughput screening method to identify mutants of 6-phosphogluconate dehydrogenase (6PGDH) from a thermophilic bacterium Moorella thermoace...

journal_title：Scientific reports

authors： Huang R,Chen H,Zhong C,Kim JE,Zhang YH

更新日期：2016-09-02 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Liu Z,Kemp TJ,Gao YT,Corbel A,McGee EE,Roa JC,Wang B,Araya JC,Shen MC,Rashid A,Hsing AW,Hildesheim A,Ferreccio C,Pfeiffer RM,Pinto LA,Koshiol J

更新日期：2020-02-11 00:00:00

abstract：:Combining MS-based proteomic data with network and topological features of such network would identify more clinically relevant molecules and meaningfully expand the repertoire of proteins derived from MS analysis. The integrative topological indexes representing 95.96% information of seven individual topological meas...

journal_title：Scientific reports

authors： Gao SG,Liu RM,Zhao YG,Wang P,Ward DG,Wang GC,Guo XQ,Gu J,Niu WB,Zhang T,Martin A,Guo ZP,Feng XS,Qi YJ,Ma YF

更新日期：2016-02-22 00:00:00

abstract：:Optical elastography is undergoing extensive development as an imaging tool to map mechanical contrast in tissue. Here, we present a new platform for optical elastography by generating sub-millimetre-scale mechanical contrast from a simple digital camera. This cost-effective, compact and easy-to-implement approach ope...

journal_title：Scientific reports

authors： Sanderson RW,Fang Q,Curatolo A,Adams W,Lakhiani DD,Ismail HM,Foo KY,Dessauvagie BF,Latham B,Yeomans C,Saunders CM,Kennedy BF

更新日期：2020-09-29 00:00:00

abstract：:A novel and convenient copper (II) bromide and 1,8-diazabicyclo[5.4.1]undec-7-ene (DBU) or 1,10-phenanthroline catalysis protocol for the construction of α-alkyl-β-keto sulfones via C(sp(3))-H bond functionalization followed by C(sp(3))-S bond formation between aryl ketones and sodium sulfinates at room temperature ha...

journal_title：Scientific reports

authors： Lan XW,Wang NX,Bai CB,Zhang W,Xing Y,Wen JL,Wang YJ,Li YH

更新日期：2015-12-18 00:00:00

abstract：:Novel natural products 7R, 8R, 7'R, 9'S-verniciasin A (1a), 7S, 8S, 7'S, 9'R- verniciasin A (1b), 7R, 8R, 7'R, 9'S-7'-methoxylverniciasin A (2a) and 7S, 8S, 7'S, 9'R-7'-methoxylverniciasin A (2b) were characterized from the seed capsule of Vernicia fordii. And the unique 9-O-9'-7, 9'-cyclo-8, 1'-neolignan skeleton wit...

journal_title：Scientific reports

authors： Zhao WH,Li N,Chu Y,Sun T,Wang J,Wang WL,Li JY,Lin B,Chen R,Hou Y

更新日期：2017-10-19 00:00:00

abstract：:We study the dynamics of an ultrafast single photon pulse in a one-dimensional waveguide two-point coupled with a Jaynes-Cummings system. We find that for any single photon input the transmissivity depends periodically on the separation between the two coupling points. For a pulse containing many plane wave components...

journal_title：Scientific reports

authors： Wang Y,Zhang Y,Zhang Q,Zou B,Schwingenschlogl U

更新日期：2016-09-22 00:00:00

abstract：:Pseudomonas aeruginosa is a major threat for immune-compromised patients. Bacterial pneumonia can induce uncontrolled and massive neutrophil recruitment ultimately leading to acute respiratory distress syndrome and epithelium damage. Interleukin-22 plays a central role in the protection of the epithelium. In this stud...

journal_title：Scientific reports

authors： Broquet A,Jacqueline C,Davieau M,Besbes A,Roquilly A,Martin J,Caillon J,Dumoutier L,Renauld JC,Heslan M,Josien R,Asehnoune K

更新日期：2017-09-08 00:00:00

abstract：:SARS-CoV-2 can transmit efficiently in humans, but it is less clear which other mammals are at risk of being infected. SARS-CoV-2 encodes a Spike (S) protein that binds to human ACE2 receptor to mediate cell entry. A species with a human-like ACE2 receptor could therefore be at risk of being infected by SARS-CoV-2. We...

journal_title：Scientific reports

authors： Wei Y,Aris P,Farookhi H,Xia X

更新日期：2021-01-18 00:00:00

abstract：:Channelrhodopsins are light-gated ion channels of green algae used for the precise temporal and spatial control of transmembrane ion fluxes. The channelrhodopsin Chrimson from Chlamydomonas noctigama allows unprecedented deep tissue penetration due to peak absorption at 590 nm. We demonstrate by electrophysiological r...

journal_title：Scientific reports

authors： Vierock J,Grimm C,Nitzan N,Hegemann P

更新日期：2017-08-30 00:00:00

abstract：:Many studies speak in favor of a rhythmic mode of listening, by which the encoding of acoustic information is structured by rhythmic neural processes at the time scale of about 1 to 4 Hz. Indeed, psychophysical data suggest that humans sample acoustic information in extended soundscapes not uniformly, but weigh the ev...

journal_title：Scientific reports

authors： Kubetschek C,Kayser C

更新日期：2021-01-27 00:00:00

abstract：:Pyoverdine (PVDI) has been reported to act both as a siderophore for scavenging iron (a key nutrient) and a signaling molecule for the expression of virulence factors. This compound is itself part of a core set of virulence factors produced by Pseudomonas aeruginosa during infections. Once secreted into the bacterial ...

journal_title：Scientific reports

authors： Bonneau A,Roche B,Schalk IJ

更新日期：2020-01-10 00:00:00

abstract：:Awarding CO2 offset credits may incentivize seagrass restoration projects and help reverse greenhouse gas (GHG) emissions from global seagrass loss. However, no study has quantified net GHG removal from the atmosphere from a seagrass restoration project, which would require coupled Corg stock and GHG flux enhancement ...

journal_title：Scientific reports

authors： Oreska MPJ,McGlathery KJ,Aoki LR,Berger AC,Berg P,Mullins L

更新日期：2020-04-30 00:00:00

abstract：:Sorafenib is a RAF inhibitor approved for several cancers, including hepatocellular carcinoma (HCC). Inhibition of RAF kinases can induce a dose-dependent "paradoxical" upregulation of the downstream mitogen-activated protein kinase (MAPK) pathway in cancer cells. It is unknown whether "paradoxical" ERK activation occ...

journal_title：Scientific reports

authors： Chen Y,Liu YC,Sung YC,Ramjiawan RR,Lin TT,Chang CC,Jeng KS,Chang CF,Liu CH,Gao DY,Hsu FF,Duyverman AM,Kitahara S,Huang P,Dima S,Popescu I,Flaherty KT,Zhu AX,Bardeesy N,Jain RK,Benes CH,Duda DG

更新日期：2017-03-09 00:00:00

abstract：:Developing the high-efficient and green synthetic method for chiral amino alcohols is an intriguing target. We have developed the Mg(2+)-doped Cu/ZnO/Al2O3 catalyst for hydrogenation of L-phenylalanine methyl ester to chiral L-phenylalaninol without racemization. The effect of different L-phenylalanine esters on this ...

journal_title：Scientific reports

authors： Zhang S,Yu J,Li H,Mao D,Lu G

更新日期：2016-09-13 00:00:00

abstract：:This study evaluates the association between indoor microbial diversity early in life and hyperactivity/inattention symptoms in children at ages 10 and 15 years.A random sample enriched with subjects with hyperactivity/inattention at age 15 years was selected from the German LISA birth cohort. Bedroom floor dust was c...

journal_title：Scientific reports

authors： Casas L,Karvonen AM,Kirjavainen PV,Täubel M,Hyytiäinen H,Jayaprakash B,Lehmann I,Standl M,Pekkanen J,Heinrich J

更新日期：2019-11-22 00:00:00

abstract：:A Late Cretaceous-aged multi-taxon nesting site from Romania preserved in three dimensions reveals the earliest example of nest site sharing yet known from the vertebrate fossil record. Eggshell and osteological evidence combined in this single accumulation demonstrate that at least four vertebrate taxa including enan...

journal_title：Scientific reports

authors： Fernández MS,Wang X,Vremir M,Laurent C,Naish D,Kaiser G,Dyke G

更新日期：2019-02-13 00:00:00

abstract：:Achieving 180° magnetization reversal with an electric field rather than a current or magnetic field is a fundamental challenge and represents a technological breakthrough towards new memory cell designs. Here we propose a mesoscale morphological engineering approach to accomplishing full 180° magnetization reversals ...

journal_title：Scientific reports

authors： Wang JJ,Hu JM,Ma J,Zhang JX,Chen LQ,Nan CW

更新日期：2014-12-16 00:00:00

abstract：:The Near-infrared Fluorescence (NIRF) molecular imaging of cancer is known to be superior in sensitivity, deeper penetration, and low phototoxicity compared to other imaging modalities. In view of an increased need for efficient and targeted imaging agents, we synthesized a NAD(P)H quinone oxidoreductase 1 (NQO1)-acti...

journal_title：Scientific reports

authors： Punganuru SR,Madala HR,Arutla V,Zhang R,Srivenugopal KS

更新日期：2019-06-12 00:00:00

abstract：:The SLRP opticin (OPTC) has been demonstrated to be produced and degraded in osteoarthritic (OA) human cartilage. Here, we investigated the in vivo effect of OPTC deficiency in OA cartilage. OA was induced in 10-week-old Optc -/- and Optc +/+ mice. Ten weeks post-surgery, cartilage was processed for histology and immu...

journal_title：Scientific reports

authors： Farrán A,Valverde-Franco G,Tío L,Lussier B,Fahmi H,Pelletier JP,Bishop PN,Monfort J,Martel-Pelletier J

更新日期：2018-01-11 00:00:00

abstract：:Activated coke (AC) has great potential in the field of low-temperature NO removal (DeNOx), especially the branch prepared by blending modification. In this study, the AC-based pyrolusite and/or titanium ore blended catalysts were prepared and applied for DeNOx. The results show blending pyrolusite and titanium ore pr...

journal_title：Scientific reports

authors： Yang L,Yao L,Lai Y,Jiang X,Jiang W

更新日期：2020-11-10 00:00:00

abstract：:Concussions carry devastating potential for cognitive, neurologic, and socio-emotional disease, but no objective test reliably identifies a concussion and its severity. A variety of neurological insults compromise sound processing, particularly in complex listening environments that place high demands on brain process...

journal_title：Scientific reports

authors： Kraus N,Thompson EC,Krizman J,Cook K,White-Schwoch T,LaBella CR

更新日期：2016-12-22 00:00:00