Incidence of gastric cancer after endoscopic resection of gastric adenoma.


BACKGROUND AND AIMS:The annual incidence of metachronous cancer after endoscopic resection (ER) of early gastric cancer (EGC) is approximately 3%. However, the incidence of gastric cancer after ER of a gastric adenoma is not known. The aim of this study was to determine whether the incidence of gastric cancer after ER of a gastric adenoma was different compared with that of metachronous cancer after ER of EGC. METHODS:We retrospectively analyzed data from patients who underwent ER for gastric neoplasia from January 2005 to August 2013. Enrolled patients were divided into 2 groups: patients with low-grade dysplasia were included in the adenoma group and patients with high-grade dysplasia or invasive neoplasia were included in the EGC group. The main outcome was the incidence of gastric cancer after ER. RESULTS:At a median follow-up of 28 months, gastric cancer newly developed in 13 adenoma patients (3.6%) and in 30 EGC patients (5.1%). The incidence rate of gastric cancer after ER was 14.4 cases per 1000 person-years in adenoma patients and 18.4 cases per 1000 person-years in EGC patients (P = .309 by the log-rank test). The hazard ratio of metachronous neoplasia in adenoma patients compared with EGC patients was 0.97 (95% confidence interval, 0.62-1.53). Metachronous tumors with invasion beyond the muscularis mucosa were more frequent in adenoma patients than in EGC patients (7/35 [20.0%] vs 3/63 [4.8%], P = .017). CONCLUSION:The incidence of gastric cancer after ER for gastric adenoma was not significantly different from that of EGC. If further prospective studies confirm these findings, careful endoscopic surveillance with the same level of intensity should be considered for both gastric adenoma and EGC patients after ER.


Gastrointest Endosc


Yoon SB,Park JM,Lim CH,Kim JS,Cho YK,Lee BI,Lee IS,Kim SW,Choi MG




Has Abstract


2016-06-01 00:00:00














  • Immunohistologic analysis of the duodenal bulb: a new method for celiac disease diagnosis in children.

    abstract:BACKGROUND AND AIMS:Anti-tissue transglutaminase antibodies (anti-tTG) have simplified celiac disease (CD) diagnosis. However, in atypical forms of CD, intestinal biopsy sampling is still required. This prospective study investigates whether histologic analysis of the duodenal bulb combined with intestinal IgA anti-tTG...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: De Leo L,Villanacci V,Ziberna F,Vatta S,Martelossi S,Di Leo G,Zanchi C,Bramuzzo M,Giudici F,Ventura A,Not T

    更新日期:2018-09-01 00:00:00

  • A prospective, randomized trial of endoscopic band ligation vs. epinephrine injection for actively bleeding Mallory-Weiss syndrome.

    abstract:BACKGROUND:Effective hemostatic treatment is mandatory for patients with actively bleeding Mallory-Weiss syndrome. This study evaluated the respective efficacy and the safety of endoscopic band ligation and endoscopic epinephrine injection in Mallory-Weiss syndrome. METHODS:Thirty-four consecutive patients with active...

    journal_title:Gastrointestinal endoscopy

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Park CH,Min SW,Sohn YH,Lee WS,Joo YE,Kim HS,Choi SK,Rew JS,Kim SJ

    更新日期:2004-07-01 00:00:00

  • Long-term follow-up results of stepwise radical endoscopic resection for Barrett's esophagus with early neoplasia.

    abstract:BACKGROUND AND AIMS:Stepwise radical endoscopic resection (SRER) has shown to be effective in eradicating Barrett's esophagus (BE) and its associated dysplasia. The aim of this study was to assess the long-term durability after successful SRER for early Barrett's neoplasia. METHODS:Patients treated with SRER for BE ≤5...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Belghazi K,van Vilsteren FGI,Weusten BLAM,Meijer SL,Bergman JJGHM,Pouw RE

    更新日期:2018-01-01 00:00:00

  • Self-approximating transluminal access technique for natural orifice transluminal endoscopic surgery: a porcine survival study (with video).

    abstract:BACKGROUND:The ability to access the abdominal cavity though a direct (modified-PEG type) gastric incision to perform natural orifice transluminal endoscopic surgery (NOTES) has been demonstrated in the literature. However, the optimal technique to access the abdomen remains unknown. OBJECTIVE:The aim of this study wa...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Pauli EM,Moyer MT,Haluck RS,Mathew A

    更新日期:2008-04-01 00:00:00

  • Prevalence of adenomas and advanced adenomas in patients in the 40- to 49-year age group undergoing screening colonoscopy because of a family history of adenoma/polyp in a first-degree relative.

    abstract:BACKGROUND:Per current guidelines, patients with a first-degree relative (FDR) with adenomas should get screened at age 40. Data on the prevalence of adenomas and advanced adenomas (AAs) in these patients are lacking. OBJECTIVE:To examine the prevalence of adenomas and AAs in 40- to 49-year-old individuals undergoing ...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Gupta A,Samadder J,Elliott E,Sethi S,Schoenfeld P

    更新日期:2012-04-01 00:00:00

  • Endotherapy versus surgery for early neoplasia in Barrett's esophagus: a meta-analysis.

    abstract:BACKGROUND:Esophagectomy is the conventional treatment for Barrett's esophagus with high-grade dysplasia and intramucosal cancer. Endotherapy is an alternative treatment. OBJECTIVE:To compare the efficacy and safety of these 2 treatments. DESIGN:PubMed, Web of Science, EMBASE, Cochrane Library and momentous meeting a...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章,meta分析,评审


    authors: Wu J,Pan YM,Wang TT,Gao DJ,Hu B

    更新日期:2014-02-01 00:00:00

  • Extent of Barrett's metaplasia: a prospective study of the serial change in area of Barrett's measured by quantitative endoscopic imaging.

    abstract:BACKGROUND:An accurate determination of the extent of Barrett's metaplasia is critical to the study of its natural history and response to therapy. Our hypothesis is that area calculations offer advantages over length estimates of Barrett's. METHODS:Changes in both measures and estimates of progression or regression b...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Kim R,Rose S,Shar AO,Weiner M,Reynolds JC

    更新日期:1997-06-01 00:00:00

  • Colonic endoscopic full-thickness biopsies: from the neuropathological analysis of the myenteric plexus to the functional study of neuromuscular transmission.

    abstract:BACKGROUND:Better understanding of the pathophysiological mechanisms involved in severe dysmotility disorders is crucial to improve patient management and identify novel therapeutic targets. Recent studies suggested that endoscopic full-thickness biopsies (eFTBs) could be developed as an alternative to surgical biopsie...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Neunlist M,Coquenlorge S,Aubert P,Duchalais-Dassonneville E,des Varannes SB,Meurette G,Coron E

    更新日期:2011-05-01 00:00:00

  • Safety experience with the duodenal-jejunal bypass liner: an endoscopic treatment for diabetes and obesity.

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    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Betzel B,Koehestanie P,Aarts EO,Dogan K,Homan J,Janssen IM,Wahab PJ,Groenen MJ,Berends FJ

    更新日期:2015-11-01 00:00:00

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    pub_type: 杂志文章,meta分析,评审


    authors: Sami SS,Subramanian V,Ortiz-Fernández-Sordo J,Saeed A,Singh S,Guha IN,Iyer PG,Ragunath K

    更新日期:2015-11-01 00:00:00

  • A meta-analysis of endoscopic submucosal dissection and EMR for early gastric cancer.

    abstract:BACKGROUND:Endoscopic submucosal dissection (ESD) was developed to overcome the problem caused by incomplete resection by conventional EMR for early gastric cancer. However, the technique of ESD had a relative higher incidence rate of complications such as bleeding and perforation because of its large wound incidence a...

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    authors: Lian J,Chen S,Zhang Y,Qiu F

    更新日期:2012-10-01 00:00:00

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    pub_type: 杂志文章


    authors: Draganov P,Hoffman B,Marsh W,Cotton P,Cunningham J

    更新日期:2002-05-01 00:00:00

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    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Massey BT,Geenen JE,Hogan WJ

    更新日期:1991-11-01 00:00:00

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    abstract:BACKGROUND:A trucut needle biopsy device that can be used to obtain specimens from the pancreas and other perigastric organs under EUS guidance has been developed and successfully tested in animals. Moreover, EUS-guided trucut needle biopsy has been used safely in humans and appears to provide more accurate results tha...

    journal_title:Gastrointestinal endoscopy

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    authors: Larghi A,Verna EC,Stavropoulos SN,Rotterdam H,Lightdale CJ,Stevens PD

    更新日期:2004-02-01 00:00:00

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    pub_type: 杂志文章


    authors: DaVee T,Coronel E,Papafragkakis C,Thaiudom S,Lanke G,Chakinala RC,Nogueras González GM,Bhutani MS,Ross WA,Weston BR,Lee JH

    更新日期:2018-06-01 00:00:00

  • A simple risk score accurately predicts in-hospital mortality, length of stay, and cost in acute upper GI bleeding.

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    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章,多中心研究


    authors: Saltzman JR,Tabak YP,Hyett BH,Sun X,Travis AC,Johannes RS

    更新日期:2011-12-01 00:00:00

  • Catheter probe assisted endoluminal US in inflammatory bowel disease.

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    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Soweid AM,Chak A,Katz JA,Sivak MV Jr

    更新日期:1999-07-01 00:00:00

  • Involvement of trainees in routine unsedated colonoscopy: review of a pilot experience.

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    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Leung FW,Aharonian HS,Guth PH,Chu SK,Nguyen BD,Simpson P

    更新日期:2008-04-01 00:00:00

  • Use of a phased vector array US catheter for EUS.

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    pub_type: 临床试验,杂志文章


    authors: Shamoun DK,Norton ID,Levy MJ,Vazquez-Sequeiros E,Wiersema MJ

    更新日期:2002-09-01 00:00:00

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    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Barawi M,Gottlieb K,Cunha B,Portis M,Gress F

    更新日期:2001-02-01 00:00:00

  • Favorable long-term outcomes of repeat endotherapy for small-intestine vascular lesions by double-balloon endoscopy.

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    journal_title:Gastrointestinal endoscopy

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    authors: Shinozaki S,Yamamoto H,Yano T,Sunada K,Hayashi Y,Shinhata H,Sato H,Despott EJ,Sugano K

    更新日期:2014-07-01 00:00:00

  • Success rate and complications of ERCP performed during hands-on training courses: a multicenter study in China.

    abstract:BACKGROUND:Hands-on endoscopy workshops are popular and valuable sources for the continuing medical education of endoscopists. Concerns, however, exist regarding clinical outcomes of procedures performed during hands-on training of ERCP. OBJECTIVE:We compared the success rates and complications between patients in the...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章,多中心研究


    authors: Liao Z,Li ZS,Leung JW,Zou XP,He LP,Jia GF,Huang Q,Ji M,Huang LY,Chao WS

    更新日期:2009-02-01 00:00:00

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    abstract::Newer fiberoptic sigmoidoscopes tend to have smaller diameter insertion shafts than older models. The extent to which this diameter affects how deeply an instrument can be inserted into the colon and the frequency with which sigmoidoscopes of different diameters could reach more proximal areas of the colon was evaluat...

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    pub_type: 杂志文章


    authors: Hawes RH,Lehman GA,O'Connor KW,Kopecky KK,Lappas JC

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    authors: Chang KJ,Nguyen P,Erickson RA,Durbin TE,Katz KD

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    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Cho E,Nakajima M,Yasuda K,Ashihara T,Kawai K

    更新日期:1993-07-01 00:00:00

  • Bacterial adherence to hydrophilic polymer-coated polyurethane stents.

    abstract::Biliary stent blockage by adherence of bacteria and formation of biofilm is a major problem in endoscopic stenting procedures. We have investigated bacterial adherence to hydrophilic polymer (Hydromer)-coated polyurethane stents in stationary and perfusion experiments. Adherence of gram negative and gram positive orga...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Jansen B,Goodman LP,Ruiten D

    更新日期:1993-09-01 00:00:00

  • Yield of prospective, noninvasive evaluation of the common bile duct combined with selective ERCP/sphincterotomy in 1390 consecutive laparoscopic cholecystectomy patients.

    abstract::The role of noninvasive evaluation of the common bile duct combined with selective preoperative endoscopic retrograde cholangiography and sphincterotomy was prospectively evaluated in 1390 consecutive patients subjected to laparoscopic cholecystectomy. Preoperative common bile duct testing included liver chemistries, ...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Rieger R,Wayand W

    更新日期:1995-07-01 00:00:00

  • Biliary changes in extrahepatic portal venous obstruction: compression by collaterals or ischemic?

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    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Dhiman RK,Puri P,Chawla Y,Minz M,Bapuraj JR,Gupta S,Nagi B,Suri S

    更新日期:1999-11-01 00:00:00

  • A comparison of magnifying and nonmagnifying colonoscopy for diagnosis of colorectal polyps: A prospective study.

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    journal_title:Gastrointestinal endoscopy

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Konishi K,Kaneko K,Kurahashi T,Yamamoto T,Kushima M,Kanda A,Tajiri H,Mitamura K

    更新日期:2003-01-01 00:00:00

  • Experimental studies of transgastric gallbladder surgery: cholecystectomy and cholecystogastric anastomosis (videos).

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    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Park PO,Bergström M,Ikeda K,Fritscher-Ravens A,Swain P

    更新日期:2005-04-01 00:00:00