Incidence of gastric cancer after endoscopic resection of gastric adenoma.


BACKGROUND AND AIMS:The annual incidence of metachronous cancer after endoscopic resection (ER) of early gastric cancer (EGC) is approximately 3%. However, the incidence of gastric cancer after ER of a gastric adenoma is not known. The aim of this study was to determine whether the incidence of gastric cancer after ER of a gastric adenoma was different compared with that of metachronous cancer after ER of EGC. METHODS:We retrospectively analyzed data from patients who underwent ER for gastric neoplasia from January 2005 to August 2013. Enrolled patients were divided into 2 groups: patients with low-grade dysplasia were included in the adenoma group and patients with high-grade dysplasia or invasive neoplasia were included in the EGC group. The main outcome was the incidence of gastric cancer after ER. RESULTS:At a median follow-up of 28 months, gastric cancer newly developed in 13 adenoma patients (3.6%) and in 30 EGC patients (5.1%). The incidence rate of gastric cancer after ER was 14.4 cases per 1000 person-years in adenoma patients and 18.4 cases per 1000 person-years in EGC patients (P = .309 by the log-rank test). The hazard ratio of metachronous neoplasia in adenoma patients compared with EGC patients was 0.97 (95% confidence interval, 0.62-1.53). Metachronous tumors with invasion beyond the muscularis mucosa were more frequent in adenoma patients than in EGC patients (7/35 [20.0%] vs 3/63 [4.8%], P = .017). CONCLUSION:The incidence of gastric cancer after ER for gastric adenoma was not significantly different from that of EGC. If further prospective studies confirm these findings, careful endoscopic surveillance with the same level of intensity should be considered for both gastric adenoma and EGC patients after ER.


Gastrointest Endosc


Yoon SB,Park JM,Lim CH,Kim JS,Cho YK,Lee BI,Lee IS,Kim SW,Choi MG




Has Abstract


2016-06-01 00:00:00














  • Extent of Barrett's metaplasia: a prospective study of the serial change in area of Barrett's measured by quantitative endoscopic imaging.

    abstract:BACKGROUND:An accurate determination of the extent of Barrett's metaplasia is critical to the study of its natural history and response to therapy. Our hypothesis is that area calculations offer advantages over length estimates of Barrett's. METHODS:Changes in both measures and estimates of progression or regression b...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Kim R,Rose S,Shar AO,Weiner M,Reynolds JC

    更新日期:1997-06-01 00:00:00

  • Prophylactic clip closure reduced the risk of delayed postpolypectomy hemorrhage: experience in 277 clipped large sessile or flat colorectal lesions and 247 control lesions.

    abstract:BACKGROUND:Endoscopic resection of large colorectal lesions is associated with high complication rates. OBJECTIVE:To evaluate the effect of prophylactic clip closure of polypectomy sites after resection of large (≥2 cm) sessile and flat colorectal lesions. DESIGN:Retrospective study. SETTING:Tertiary referral center...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Liaquat H,Rohn E,Rex DK

    更新日期:2013-03-01 00:00:00

  • EUS-guided cholecystenterostomy: a new technique (with videos).

    abstract:BACKGROUND:The cornerstone of management for acute cholecystitis is cholecystectomy. However, surgical intervention is contraindicated in the occasional patient. EUS-guided transduodenal gallbladder drainage may represent an effective minimally invasive alternative. OBJECTIVES:To describe a new technique, EUS-guided c...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Kwan V,Eisendrath P,Antaki F,Le Moine O,Devière J

    更新日期:2007-09-01 00:00:00

  • Linear mucosal defect may be characteristic of lansoprazole-associated collagenous colitis.

    abstract:BACKGROUND:Although some cases of collagenous colitis have been induced by lansoprazole (LPZ), the clinicopathologic features of LPZ-associated collagenous colitis have not been elucidated. OBJECTIVE:To elucidate the clinical, endoscopic, and histopathologic features of LPZ-associated collagenous colitis. DESIGN:Retr...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Umeno J,Matsumoto T,Nakamura S,Jo Y,Yada S,Hirakawa K,Yoshimura R,Yamagata H,Kudo T,Hirano A,Gushima M,Yao T,Nakashima Y,Iida M

    更新日期:2008-06-01 00:00:00

  • Endoscopic therapy for bile leak based on a new classification: results in 207 patients.

    abstract:BACKGROUND:Bile leak is among the most common complications of cholecystectomy. Endoscopic therapy is empiric; a systematic approach to management of bile leak has not been established. METHODS:The severity of bile leak was classified by endoscopic retrograde cholangiography into low grade (leak identified only after ...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Sandha GS,Bourke MJ,Haber GB,Kortan PP

    更新日期:2004-10-01 00:00:00

  • Characterization of buried glands before and after radiofrequency ablation by using 3-dimensional optical coherence tomography (with videos).

    abstract:BACKGROUND:Radiofrequency ablation (RFA) is an endoscopic technique used to eradicate Barrett's esophagus (BE). However, such ablation can commonly lead to neosquamous epithelium overlying residual BE glands not visible by conventional endoscopy and may evade detection on random biopsy samples. OBJECTIVE:To demonstrat...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Zhou C,Tsai TH,Lee HC,Kirtane T,Figueiredo M,Tao YK,Ahsen OO,Adler DC,Schmitt JM,Huang Q,Fujimoto JG,Mashimo H

    更新日期:2012-07-01 00:00:00

  • Acute extraluminal hemorrhage associated with EUS-guided fine needle aspiration: frequency and clinical significance.

    abstract:BACKGROUND:Complications with EUS-guided fine needle aspiration cytology (EUS-guided FNA) are rare and include perforation, infection, pancreatitis, and intraluminal bleeding. To date, the ultrasound appearance and clinical significance of perilesional bleeding during EUS-guided FNA have not been described. The aim of ...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Affi A,Vazquez-Sequeiros E,Norton ID,Clain JE,Wiersema MJ

    更新日期:2001-02-01 00:00:00

  • Meperidine need not be proscribed during sphincter of Oddi manometry.

    abstract::Meperidine is routinely proscribed during sphincter of Oddi manometry because narcotics have been associated with spasm of the sphincter of Oddi. We have performed a prospective study of the effect of meperidine on sphincter of Oddi manometry in 18 patients undergoing manometry for suspected sphincter dysfunction. Aft...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Elta GH,Barnett JL

    更新日期:1994-01-01 00:00:00

  • Long-term outcomes of endoscopic treatment of aberrant hepatic duct injuries after cholecystectomy.

    abstract:BACKGROUND AND AIMS:Right aberrant hepatic ducts are an anatomic variant with clinical relevance because of the risk of injury during cholecystectomy. Treatment options for aberrant hepatic duct injuries are not standardized. This study aims to analyze the long-term results of endoscopic treatment of aberrant hepatic d...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Tringali A,Massinha P,Schepis T,Landi R,Boškoski I,Perri V,Bove V,Costamagna G

    更新日期:2020-03-01 00:00:00

  • Laparoscopy-assisted versus balloon enteroscopy-assisted ERCP in bariatric post-Roux-en-Y gastric bypass patients.

    abstract:BACKGROUND:Data on balloon enteroscopy-assisted ERCP (BEA-ERCP) versus laparoscopy-assisted ERCP (LA-ERCP) in post-Roux-en-Y gastric bypass (RYGB) patients are lacking. OBJECTIVES:To compare BEA-ERCP with LA-ERCP in post-RYGB patients and to identify factors that predict therapeutic success with BEA-ERCP. DESIGN:Retr...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Schreiner MA,Chang L,Gluck M,Irani S,Gan SI,Brandabur JJ,Thirlby R,Moonka R,Kozarek RA,Ross AS

    更新日期:2012-04-01 00:00:00

  • Risk factors for post-ERCP pancreatitis in wire-guided cannulation for therapeutic biliary ERCP.

    abstract:BACKGROUND:Wire-guided cannulation (WGC) was reported to decrease post-ERCP pancreatitis (PEP), but risk factors for PEP in WGC are not fully elucidated. OBJECTIVE:To evaluate the incidence and risk factors of PEP in WGC. DESIGN:Single-center retrospective study. SETTING:Academic center. PATIENTS:A total of 800 con...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Nakai Y,Isayama H,Sasahira N,Kogure H,Sasaki T,Yamamoto N,Saito K,Umefune G,Akiyama D,Kawahata S,Matsukawa M,Saito T,Hamada T,Takahara N,Mizuno S,Miyabayashi K,Mohri D,Hirano K,Tada M,Koike K

    更新日期:2015-01-01 00:00:00

  • Self-approximating transluminal access technique for natural orifice transluminal endoscopic surgery: a porcine survival study (with video).

    abstract:BACKGROUND:The ability to access the abdominal cavity though a direct (modified-PEG type) gastric incision to perform natural orifice transluminal endoscopic surgery (NOTES) has been demonstrated in the literature. However, the optimal technique to access the abdomen remains unknown. OBJECTIVE:The aim of this study wa...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Pauli EM,Moyer MT,Haluck RS,Mathew A

    更新日期:2008-04-01 00:00:00

  • EUS characteristics of celiac ganglia with cytologic and histologic confirmation.

    abstract:BACKGROUND:Celiac ganglia have not been previously identified by EUS. OBJECTIVE:To assess whether celiac ganglia can be detected by EUS and to define their characteristics. DESIGN:Retrospective review followed by prospective study. METHODS:Retrospective characterization was performed of all celiac ganglia that were ...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Gerke H,Silva RG Jr,Shamoun D,Johnson CJ,Jensen CS

    更新日期:2006-07-01 00:00:00

  • Endoscopic sclerotherapy for portal hypertension due to extrahepatic obstruction: long-term follow-up.

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    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Bhargava DK,Dwivedi M,Dasarathy S,Arora A

    更新日期:1989-07-01 00:00:00

  • A randomized controlled trial of pentoxifylline for the prevention of post-ERCP pancreatitis.

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    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章,随机对照试验


    authors: Kapetanos D,Kokozidis G,Christodoulou D,Mistakidis K,Sigounas D,Dimakopoulos K,Kitis G,Tsianos EV

    更新日期:2007-09-01 00:00:00

  • Endoscopic treatment of gastroesophageal varices in young infants with cyanoacrylate glue: a pilot study.

    abstract:BACKGROUND:In children, endoscopic sclerotherapy and variceal ligation (EVL) are the most used techniques for the treatment of gastroesophageal variceal bleeding (VB). However, these techniques achieve poor results in cases of gastric variceal bleeding, and EVL is not applicable in young infants. OBJECTIVE:Our purpose...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Rivet C,Robles-Medranda C,Dumortier J,Le Gall C,Ponchon T,Lachaux A

    更新日期:2009-05-01 00:00:00

  • The natural history of untreated duodenal and ampullary adenomas in patients with familial adenomatous polyposis followed in an endoscopic surveillance program.

    abstract:BACKGROUND:Endoscopic surveillance is recommended for patients with familial adenomatous polyposis (FAP) because of the high prevalence of duodenal adenomas and the risk of periampullary cancer. The aim of this study was to assess the natural history of untreated duodenal and ampullary adenomas in FAP patients during s...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Burke CA,Beck GJ,Church JM,van Stolk RU

    更新日期:1999-03-01 00:00:00

  • Double balloon endoscopy for pancreatic and biliary access in altered anatomy (with videos).

    abstract:BACKGROUND:Access to the papilla of Vater or enteral anastomoses to the biliary tract or pancreatic duct is difficult in patients with altered anatomy. The usual approach to the papilla of Vater with a side-viewing duodenoscope, designed for passage through the stomach, pyloric channel, and proximal duodenum, is not su...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Haber GB

    更新日期:2007-09-01 00:00:00

  • Endoscopy and EUS are key for effective surveillance and management of duodenal adenomas in familial adenomatous polyposis.

    abstract:BACKGROUND:Patients with familial adenomatous polyposis (FAP) are prone to developing duodenal adenoma and cancer. Optimal surveillance and management of these adenomas are not well established. OBJECTIVE:We assessed the outcome of FAP patients undergoing intense multimodal surveillance and subsequent endoscopic resec...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Gluck N,Strul H,Rozner G,Leshno M,Santo E

    更新日期:2015-04-01 00:00:00

  • A comparison of laser therapy, plastic stents, and expandable metal stents for palliation of malignant dysphagia in patients without a fistula.

    abstract:BACKGROUND:Many options are available for palliation of inoperable malignant stenoses of the esophagus. We report our experience with different modalities of endoscopic therapy. METHODS:From 1986 to 1996, we treated 125 patients with dysphagia caused by unresectable malignant tumors with endoscopic therapy. Seventy pa...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Gevers AM,Macken E,Hiele M,Rutgeerts P

    更新日期:1998-10-01 00:00:00

  • The detection of premalignant colon polyps during colonoscopy is stable throughout the workday.

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    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Freedman JS,Harari DY,Bamji ND,Bodian CA,Kornacki S,Cohen LB,Miller KM,Aisenberg J

    更新日期:2011-06-01 00:00:00

  • Snare cautery debridement prior to Nd:YAG photoablation improves treatment efficiency of broad-based adenomas of the colorectum.

    abstract::Forty-six patients who underwent piecemeal resection of large, sessile villous adenomas followed by immediate laser photoablative therapy are presented. In contrast to previously published series utilizing laser alone, prior snare resection of such lesions provides copious tissue for histologic analysis, decreases the...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Low DE,Kozarek RA

    更新日期:1989-07-01 00:00:00

  • A controlled study of human resting gastric mucosal blood flow by endoscopic laser-Doppler flowmetry.

    abstract::We investigated regional variation in resting focal gastric mucosal blood flow obtained by endoscopic laser-Doppler flowmetry in patients with symptoms of dyspepsia or peptic ulcer (N = 12) and asymptomatic healthy volunteers (N = 6). Mucosal blood flow was measured for 1 min at the duodenum (first part), prepylorus, ...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Gana TJ,Soenen GM,Koo J

    更新日期:1990-05-01 00:00:00

  • Variations between endoscopists in rates of detection of colorectal neoplasia and their impact on a regional screening program based on colonoscopy after fecal occult blood testing.

    abstract:BACKGROUND:There are few data about the performance variability among endoscopists participating to nationwide or regionwide colorectal cancer screening programs. OBJECTIVE:To assess the variability of neoplasia detection rates among endoscopists participating in a regional colorectal cancer screening program based on...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Bretagne JF,Hamonic S,Piette C,Manfredi S,Leray E,Durand G,Riou F

    更新日期:2010-02-01 00:00:00

  • EUS-guided FNA diagnostic yield of malignancy in solid pancreatic masses: a benchmark for quality performance measurement.

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    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章,多中心研究


    authors: Savides TJ,Donohue M,Hunt G,Al-Haddad M,Aslanian H,Ben-Menachem T,Chen VK,Coyle W,Deutsch J,DeWitt J,Dhawan M,Eckardt A,Eloubeidi M,Esker A,Gordon SR,Gress F,Ikenberry S,Joyce AM,Klapman J,Lo S,Maluf-Filho F,Nic

    更新日期:2007-08-01 00:00:00

  • Abdominal compression during endoscopy (the Bolster technique) demonstrates hidden Schatzki rings (with videos).

    abstract:BACKGROUND AND AIMS:Schatzki rings are found in the distal esophagus, are associated with hiatal hernias, and present with intermittent dysphagia to solid foods. They can be identified by radiology (GI series or barium swallow studies) or endoscopy. Rings are not always visualized during endoscopy in patients in whom t...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Jouhourian C,Bonis PA,Guelrud M

    更新日期:2016-05-01 00:00:00

  • Endoscopic overestimation of colorectal polyp size.

    abstract:BACKGROUND AND AIMS:Polyp size ≥ 1 cm triggers more frequent colonoscopic surveillance, yet size is typically based on subjective endoscopic estimates. We sought to compare contemporary assessments of polyp size by endoscopic estimation and pathology measurement. METHODS:Colonoscopy and pathology reports were reviewed...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Anderson BW,Smyrk TC,Anderson KS,Mahoney DW,Devens ME,Sweetser SR,Kisiel JB,Ahlquist DA

    更新日期:2016-01-01 00:00:00

  • Death after PEG: results of the National Confidential Enquiry into Patient Outcome and Death.

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    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Johnston SD,Tham TC,Mason M

    更新日期:2008-08-01 00:00:00

  • EUS in cirrhotic patients with and without prior variceal hemorrhage in comparison with noncirrhotic control subjects.

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    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章


    authors: Faigel DO,Rosen HR,Sasaki A,Flora K,Benner K

    更新日期:2000-10-01 00:00:00

  • Radiofrequency ablation combined with biliary stent placement versus stent placement alone for malignant biliary strictures: a systematic review and meta-analysis.

    abstract:BACKGROUND AND AIMS:Unresectable malignant biliary strictures are generally managed by palliative stent placement for drainage of biliary tree. Recently, radiofrequency ablation (RFA) has been used to improve the patency of biliary stents in these patients. Several studies have evaluated the effectiveness of biliary st...

    journal_title:Gastrointestinal endoscopy

    pub_type: 杂志文章,meta分析,评审


    authors: Sofi AA,Khan MA,Das A,Sachdev M,Khuder S,Nawras A,Lee W

    更新日期:2018-04-01 00:00:00