Abstract：
OBJECTIVES:Determine if a brief intervention (BI) reduces the negative consequences of drug use/misuse among adult emergency department (ED) patients, and identify patients more likely to benefit from the BI. METHODS:This randomized, controlled trial enrolled 1026 18-64 year-old ED patients whose drug misuse indicated a needed for a BI. Differences in total Inventory of Drug Use Consequences (InDUC) scores between the treatment (BI) and control arms (no BI) were assessed every 90 days over a one-year period. Regression models were constructed to identify demographic and clinical factors associated with greater reductions in total InDUC scores. RESULTS:Although total InDUC scores decreased for both the treatment and control arms, there were no differences in scores between the treatment and the control arms at baseline at each follow-up. In the regression analyses, participants who were not using drugs or received drug treatment in the past 90 days generally had lower InDUC scores at each follow-up. CONCLUSIONS:Although negative consequences decreased in both study arms over time, receiving a BI did not lead to a greater reduction in the negative consequences of drug misuse than not receiving a BI. Of importance in the design of future ED drug misuse interventions, participants who were successful in stopping their drug misuse or receiving drug treatment did show fewer negative consequences of drug use/misuse.
journal_name
Drug Alcohol Dependjournal_title
Drug and alcohol dependenceauthors
Guan W,Liu T,Baird JR,Merchant RCdoi
10.1016/j.drugalcdep.2015.10.007subject
Has Abstractpub_date
2015-12-01 00:00:00pages
44-53eissn
0376-8716issn
1879-0046pii
S0376-8716(15)01689-0journal_volume
157pub_type
杂志文章,随机对照试验abstract：BACKGROUND:Substance use disorders consistently rank among the most stigmatized conditions worldwide. Thus, substance use stigma fosters health inequities among persons with substance use disorders and remains a key barrier to successful screening and treatment efforts. Current efforts to measure substance use stigma a...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2016.02.019
更新日期：2016-05-01 00:00:00
abstract：BACKGROUND:Reduced cardio-vascular health has been found in patients suffering from alcohol dependence. Low cardio-respiratory fitness is an independent predictor of cardio-vascular disease. METHODS:We investigated physical fitness in 22 alcohol-dependent patients 10 days after acute alcohol withdrawal and compared re...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2013.03.016
更新日期：2013-10-01 00:00:00
abstract：:In this paper we estimate the risk of becoming cannabis dependent within 24 months after first use of cannabis and examine subgroup variation in this risk. The study estimates are based on the National Household Survey on Drug Abuse conducted during 2000-2001, with a representative sample of U.S. residents ages 12 and...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2004.11.014
更新日期：2005-07-01 00:00:00
abstract：BACKGROUND:An emerging area of preclinical research has investigated whether drug use in parents prior to conception influences drug responsivity in their offspring. The present work sought to further characterize such effects with cannabis by examining whether a parental THC history modified locomotor sensitization to...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2020.107985
更新日期：2020-07-01 00:00:00
abstract：:Drug dependence units (DDUs) form the cornerstone of government policy response to problem drug taking. Yet we know surprisingly little about the facilities that they can provide and what treatment policies they adopt. This paper constitutes a modest attempt to fill some of the gaps in our knowledge and points to the ...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/0376-8716(85)90037-7
更新日期：1985-05-01 00:00:00
abstract：INTRODUCTION:In Florida, since 1998, identical survey items have been used to measure youth smoking status for the CDC sponsored state school-based survey and the tobacco control program evaluation telephone survey. The two surveys should parallel one another to track tobacco use. Tobacco items collected in the two sur...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2015.01.024
更新日期：2015-04-01 00:00:00
abstract：BACKGROUND:Females exhibit more rapid escalation of cocaine use and enhanced cocaine-taking behavior as compared to males. While ovarian hormones likely play a role in this increased vulnerability, research has yet to examine the role of estradiol in affecting the behavioral and neurological response to cocaine in a br...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2013.09.009
更新日期：2014-02-01 00:00:00
abstract：:Zipeprol is a non-opioid cough suppressor agent recently abused in Italy. Clinical reports from 30 street abusers show that the drug in high doses has a definite abuse liability and dependence potential. Many of its effects were identical to those induced by opiates, although specific dysperceptive symptoms were commo...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/0376-8716(91)90030-3
更新日期：1991-03-01 00:00:00
abstract：BACKGROUND:Homeless men may be at particular risk for the negative health effects of substance use. This cross-sectional study investigates the individual and personal network risk factors associated with substance use in this vulnerable population. METHODS:Participants were a representative probability sample of 305 ...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2011.04.011
更新日期：2011-11-01 00:00:00
abstract：:The rearrest rates among Norwegian drugged (n=1102) and a group of drunken drivers (n=850) (BAC: 0.16-0.19%) apprehended during 1992, were 57% (n=629) and 28% (n=238), respectively, when followed prospectively for 7 years. The most important risk factors for recidivism among drugged drivers were previous arrests for d...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/s0376-8716(01)00187-9
更新日期：2002-03-01 00:00:00
abstract：AIMS:Carisoprodol is a muscle relaxant that acts at the GABA(A) receptor. Concerns about the abuse liability of carisoprodol are increasing, but evidence that carisoprodol produces tolerance and a significant withdrawal syndrome has yet to be established. The purpose of the current study was to determine if repeated ad...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2011.10.010
更新日期：2012-06-01 00:00:00
abstract：BACKGROUND:Although the interaction of brain volume with amphetamine-type stimulants (ATS) and cocaine has been investigated in chronically dependent individuals, little is known about structural differences that might exist in individuals who consume ATS and cocaine occasionally but are not dependent on these drugs. ...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2013.11.018
更新日期：2014-02-01 00:00:00
abstract：BACKGROUND:Cross-sectional studies have demonstrated gender-related differences in the associations between problem-gambling severity and substance-use disorders; however, these associations have not been examined longitudinally. We aimed to examine the prospective associations between problem-gambling severity and inc...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2013.05.002
更新日期：2013-11-01 00:00:00
abstract：BACKGROUND:In Chile, concerns mount about escalating cannabis use. Thus, it is important to have tools for early identification of at-risk users. The Cannabis Use Problems Identification Test (CUPIT) is a useful screening tool, and the aim of this study was to examine the psychometric properties of its Spanish version ...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2016.10.032
更新日期：2017-01-01 00:00:00
abstract：:Ninety alcoholic patients with the secondary affective disorders (anxiety, depression) were divided into four groups. Patients in the first group received GABAB receptor ligands (baclofen), those in the second group, diazepam, those in the third group, amitriptyline and those in the fourth group, placebo. The results ...
journal_title：Drug and alcohol dependence
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0376-8716(93)90057-w
更新日期：1993-09-01 00:00:00
abstract：BACKGROUND:This study assesses differences in social norms towards smoking and vaping among youth across countries (England, Canada, US) and smoking and vaping status. METHODS:Data are from the 2017 ITC Youth Tobacco and Vaping Survey, among youth age 16-19 in England (N = 3444), Canada (N = 3327), and US (N = 3509). ...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2019.107635
更新日期：2019-12-01 00:00:00
abstract：BACKGROUND:Incarceration is common among people who inject drugs. Prior research has shown that incarceration is a marker of elevated risk for opioid overdose, suggesting that the criminal justice system may be an important, under-utilized venue for implementing overdose prevention strategies. To better understand the ...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2015.06.023
更新日期：2015-09-01 00:00:00
abstract：BACKGROUND:Relatively little is known about factors that may lead to the development of a substance use disorder (SUD), across a range of drug classes. This study aimed to identify factors that predict the likelihood of transition from use to SUD and the speed with which this may occur at the population level, with a f...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2018.10.010
更新日期：2019-01-01 00:00:00
abstract：OBJECTIVE:To examine the prevalence and correlates of substance use during pregnancy among women in the United States. METHODS:We analyzed data from pregnant (n=1800) and non-pregnant women (n=37,527) aged 15-44 years who participated in the 2002 or 2003 National Survey on Drug Use and Health, a nationally representat...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2008.07.010
更新日期：2009-01-01 00:00:00
abstract：:This paper provides a detailed analysis of the 2-year outcomes for 351 drug misusers allocated on an intention-to-treat basis to methadone maintenance or methadone reduction treatments. Both groups showed substantial reductions in their use of illicit drugs and in other outcome areas. However, whereas most methadone m...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/s0376-8716(00)00211-8
更新日期：2001-05-01 00:00:00
abstract：BACKGROUND:We explored the association between alcohol use and condomless receptive (CRAI) and insertive (CIAI) anal intercourse within partnership contexts of men who have sex with men (MSM) and transgender women (TGW) in Lima, Peru. METHODS:From 2012-2014, we surveyed men and TGW (n=1607) who reported anal intercour...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2016.10.033
更新日期：2017-01-01 00:00:00
abstract：INTRODUCTION:A growing area of research suggests that neuroimmunity may impact the pharmacology of opioids. Microglia is a key component of the brain immunity. Preclinical and clinical studies have demonstrated that microglial modulators may improve morphine-induced analgesia and prevent the development of tolerance an...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2016.10.037
更新日期：2017-01-01 00:00:00
abstract：OBJECTIVE:This study examined the association between baseline substance use and mental health, and non-partner violence trajectories among youth presenting to an urban emergency department who screened positive for drug use. Non-partner violence is physically violent victimization or aggression involving someone other...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2020.108117
更新日期：2020-06-15 00:00:00
abstract：:In this discussion of contributed papers for the special issue of DAD, the author draws attention to early American laws concerning cannabis and to statements made about the epidemiology of cannabis smoking and other drug use between 1858 and the contemporary scene, with coverage of opium, heroin, tobacco, alcohol, co...
journal_title：Drug and alcohol dependence
pub_type： 历史文章,杂志文章
doi：10.1016/j.drugalcdep.2012.04.006
更新日期：2012-06-01 00:00:00
abstract：BACKGROUND:Regional variation in pharmacy-dispensed naloxone rates could create access disparities that undermine the effectiveness of this approach. We explored individual and public health unit (PHU)-level determinants of regional variation in naloxone distribution through the Ontario Naloxone Program for Pharmacies....
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2020.108238
更新日期：2020-11-01 00:00:00
abstract：INTRODUCTION:The objective of this study was to understand how adolescent substance use patterns may lead to negative mental health outcomes. METHODS:Data from adolescents (12-17 years old at baseline, Wave 1) who participated in the first 3 waves of the Population Assessment of Health and Tobacco (PATH) study were us...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2020.108385
更新日期：2021-01-01 00:00:00
abstract：:Studies on ethanol-exposed animals have revealed changes in anionic phospholipids in brain membranes. The intention of this study was to investigate whether there was a similar effect on man. Assuming platelets to be an adequate model for CNS synaptosomes, concentration and fatty acid composition of anionic phospholip...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/0376-8716(86)90065-7
更新日期：1986-02-01 00:00:00
abstract：BACKGROUND:Although neighborhoods with more collective efficacy have better health in general, recent work suggests that social norms and collective efficacy may in combination influence health behaviors such as smoking. METHODS:Using data from the New York Social Environment Study (conducted in 2005; n=4000), we exam...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2008.09.012
更新日期：2009-02-01 00:00:00
abstract：BACKGROUND:This article reports on the first web-based implementation of an opioid-overdose prevention, recognition and response training for professional first responders. The training was disseminated nationally over one listserv in November 2014. The same year, following Act 139, which mandated the provision of an o...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2016.10.003
更新日期：2016-12-01 00:00:00
abstract：:Although there has been growing concern in recent years about an escalation in the use of LSD and other hallucinogens, little is known about the distribution of the use of these drugs in the United States population. In order to fill this gap, we used generalized additive models to analyze data from the 1988, 1990, an...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/s0376-8716(96)01297-5
更新日期：1996-12-11 00:00:00
