Abstract:
:An original stereotactic radiosurgical approach coupling a) Talairach's stereotactic methodology, b) a specially devised mechanical system, and c) a linear accelerator is detailed. The authors present their preliminary results on 66 patients with nonsurgical intracranial arteriovenous malformations. The doses delivered for treatment varied from 20 to 70 Gy. Doses of no more than 40 Gy were used in 80% of patients. An angiographic study was performed when the computed tomographic scan controls showed relevant modifications of the lesion volume. Total obliteration was obtained in 27 of the 41 patients (65.8%) who were followed up for at least 24 months. The percentage of the cured patients is significantly higher when a) the entire malformation is included in the 75% isodose (96%) and b) the maximum diameter of the lesion is less than 12 mm (81%). Two patients died of rebleeding at 18 and 29 months after treatment.
journal_name
Neurosurgeryjournal_title
Neurosurgeryauthors
Betti OO,Munari C,Rosler Rdoi
10.1227/00006123-198903000-00001subject
Has Abstractpub_date
1989-03-01 00:00:00pages
311-21issue
3eissn
0148-396Xissn
1524-4040journal_volume
24pub_type
杂志文章相关文献
NEUROSURGERY文献大全abstract::The authors review their experience with a dorsolateral approach to the anterior rim of the foramen magnum and adjacent region. The operative technique includes exposure of the vertebral artery at C1, partial resection of the occipital condyle and lateral atlantal mass, and extradural drilling of the jugular tubercle....
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-199112000-00002
更新日期:1991-12-01 00:00:00
abstract:OBJECTIVE:Schwannomas that arise from the trigeminal nerve are rare and are usually managed by surgical resection. The role of radiosurgery in the care of patients with these basal tumors remains to be defined. METHODS:We reviewed the clinical presentation, management, and outcomes for 16 trigeminal schwannoma patient...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-199907000-00002
更新日期:1999-07-01 00:00:00
abstract:INTRODUCTION:Three-dimensional computed tomographic angiography (3-D-CTA) can be used to evaluate cerebrovascular disease. A potential limitation of this technology is obscuration of vascular anatomy by bone. In view of this, we developed a method for bone-free rendering using iterative relative fuzzy connectedness (IR...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-200207000-00044
更新日期:2002-07-01 00:00:00
abstract:OBJECTIVE:We evaluated a combined technique designed for procedures requiring intraoperative language mapping. We planned to induce general anesthesia with endotracheal intubation and hyperventilation and then to awaken and extubate the patient for speech testing. After the latter, endotracheal reintubation and general...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-199806000-00069
更新日期:1998-06-01 00:00:00
abstract::Nine pineal area lesions were operated upon by the infratentorial-supracerebellar approach. There was one operative death and one death due to disseminated germinoma recurrence 2 1/2 years postoperatively. The remaining seven patients have shown no sign of recurrence and are neurologically normal. The surgical method ...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-197707000-00008
更新日期:1977-07-01 00:00:00
abstract:BACKGROUND:The Pipeline Embolization Device is a widely utilized flow diverter in the treatment of intracranial aneurysms. OBJECTIVE:To assess the incidence, clinical significance, predictors, and outcomes of in-Pipeline stenosis (IPS). METHODS:Angiographic studies in 139 patients treated between 2011 and 2013 were i...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/NEU.0000000000000908
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE AND IMPORTANCE:We describe a case of brainstem cavernous angioma resected by the subtemporal, anterior transpetrosal approach, selected on the basis of three-dimensional anisotropy contrast (3-DAC) imaging. CLINICAL PRESENTATION:A 64-year-old woman presented with sudden headache and gait disturbance. Anatomi...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.NEU.0000193531.59606.CB
更新日期:2006-02-01 00:00:00
abstract::The natural history of postirradiation extracranial cerebrovascular disease is uncertain. Previous reported cases spanning 20 years of carotid surgery are difficult to evaluate, because patients may sometimes have unspecified symptoms, physical examinations, postoperative results, and follow-up. Also, the evolution of...
journal_title:Neurosurgery
pub_type: 杂志文章,评审
doi:10.1227/00006123-198902000-00004
更新日期:1989-02-01 00:00:00
abstract:BACKGROUND:Obtaining a watertight reconstruction with a fat graft with wide sellar exposures can be challenging, including the risk of reinstating mass effect with the fat graft. The alternative, a vascularized pedicle nasoseptal flap, may require several days to heal and still has a > 5% cerebrospinal fluid (CSF) leak...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/NEU.0b013e318241af25
更新日期:2012-09-01 00:00:00
abstract::Coronary thrombolysis with streptokinase or tissue plasminogen activator is useful for the treatment of acute myocardial infarction in selected patients. This treatment is associated with local hemorrhagic complications and age-related cerebral hemorrhage. Coronary thrombolysis is contraindicated in patients with tran...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-199209000-00025
更新日期:1992-09-01 00:00:00
abstract::Radiosurgery is fundamentally the harnessing of energy and delivering it to a focal target for a therapeutic effect. The evolution of radiosurgical technology and practice has served toward refining methodologies for better conformal energy delivery. In the past, this has resulted in developing strategies for improved...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.neu.0000306089.22894.4e
更新日期:2007-12-01 00:00:00
abstract:BACKGROUND:Artificial neural networks (ANNs) excel at analyzing challenging data sets and can be exceptional tools for decision support in clinical environments. The present study pilots the use of ANNs for determining prognosis in neuro-oncology patients. OBJECTIVE:To determine whether ANNs perform better at predicti...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/NEU.0b013e31828ea04b
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVE:To determine whether adult human dorsal root ganglion neurons can be isolated and maintained in long-term tissue culture, where they would extend processes. METHODS:Dorsal root ganglia were removed from adult human organ donors within 2 hours of clamping the aorta. They were then treated with enzymes for one...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-199803000-00054
更新日期:1998-03-01 00:00:00
abstract:OBJECTIVE:To report our experience in treatment of arteriovenous malformations (AVMs) using a new liquid embolic agent, Onyx (Micro Therapeutics, Inc., Irvine, CA). METHODS:Between January 1998 and May 1999, 23 patients (8 men and 15 women) were treated. The patients' average age was 40 years, with seizure being the m...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-200105000-00003
更新日期:2001-05-01 00:00:00
abstract:BACKGROUND:Spinal cord cavernous malformations (CMs) are associated with 2 types of angiographically occult "cryptic venous anomalies," which differ in location with respect to the spinal cord. The anatomic distinction between superficial and intramedullary is important in that the latter heighten the risks of CM resec...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/NEU.0b013e31825d8f9a
更新日期:2012-09-01 00:00:00
abstract:OBJECTIVE:We report the safety and feasibility of using convection-enhanced delivery to administer Cotara (Peregrine Pharmaceuticals, Inc., Tustin, CA), a novel radioimmunotherapeutic agent, to patients with malignant glioma. METHODS:Between April 1998 and November 2002, 51 patients with histologically confirmed malig...
journal_title:Neurosurgery
pub_type: 杂志文章,多中心研究
doi:10.1227/01.neu.0000159649.71890.30
更新日期:2005-06-01 00:00:00
abstract::Unilateral hydrocephalus in an adult was caused by obstruction of the left foramen of Monro by an intraventricular venous malformation. Magnetic resonance imaging of the region of the foramen of Monro demonstrated the lesion, which subsequently was confirmed to be a venous malformation by angiography and surgery. ...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-199004000-00017
更新日期:1990-04-01 00:00:00
abstract:BACKGROUND:The lateral extracavitary approach (LECA) and costotransversectomy (CTE) are 2 dorsolateral approaches that avoid entrance into the pleural cavity and facilitate ventral decompression. The indications and outcomes of each of these approaches have not been fully defined in the literature. OBJECTIVE:To assess...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/NEU.0b013e3182706102
更新日期:2012-12-01 00:00:00
abstract:UNLABELLED:BAC1KGROUND: AG1478 is an epithelial growth factor receptor tyrosine kinase inhibitor. Epithelial growth factor receptor regulates the expression of cadherin in cells via its action on β-catenin, and N-cadherin downregulation promotes infiltration and cerebrospinal fluid (CSF) dissemination of glioma cells. ...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/NEU.0b013e318215a3d0
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:Lumbar spine degenerative pathologies are prevalent in the United States. The health benefit of spine surgery in the elderly has been questioned. OBJECTIVE:To compare effectiveness, morbidity, and quality of care associated with surgical management of degenerative lumbar spinal disorders in elderly vs nonel...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/NEU.0000000000000952
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:Organized general surgery has recently proposed creation of a new acute care surgery subspecialty to include emergency care of basic neurosurgical and orthopedic surgical problems. Little is known about neurosurgical attitudes toward this proposal and alternative methods of improving access to emergency neuro...
journal_title:Neurosurgery
pub_type: 共识发展会议,杂志文章
doi:10.1227/NEU.0b013e318209cde0
更新日期:2011-04-01 00:00:00
abstract:OBJECTIVE:Several studies have shown that human gliomas contain a small population of cells with stem cell-like features. It has been proposed that these "cancer stem cells" may be uniquely responsible for glioma formation and recurrence. However, human gliomas also contain an abundance of cells that closely resemble m...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.neu.0000316019.28421.95
更新日期:2008-02-01 00:00:00
abstract:INTRODUCTION:Circumferential aneurysms, which incorporate >180 degrees of the circumference of the parent vessel, present a unique therapeutic challenge, particularly in circumstances in which a deconstructive treatment strategy is not feasible. We detail a novel technique for endovascular parent vessel reconstruction ...
journal_title:Neurosurgery
pub_type: 杂志文章,多中心研究
doi:10.1227/01.neu.0000186036.35823.10
更新日期:2005-12-01 00:00:00
abstract:BACKGROUND:Cerebral vasospasm is an independent predictor of poor outcome after subarachnoid hemorrhage (SAH). The nitric oxide-cyclic guanosine monophosphate (NO-cGMP) vasodilatory pathway is strongly implicated in its pathophysiology. Preliminary studies suggest that phosphodiesterase 5 (PDE5), an enzyme that degrade...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/NEU.0b013e31822ec2b0
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVE AND IMPORTANCE:Intraoperative aneurysmal rupture represents a potentially catastrophic event. We describe the use of an intravenous adenosine bolus to induce transient cardiac asystole to control a severe intraoperative aneurysmal rupture. This treatment resulted in a brief period of severe hypotension, which...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-200007000-00053
更新日期:2000-07-01 00:00:00
abstract:OBJECTIVE:It is still debated to what extent intraoperative electrophysiological techniques contribute to the outcome of subthalamic nucleus (STN) deep brain stimulation (DBS). Intraoperative electrophysiological recordings for identification of the STN can be made with one electrode or with multiple, simultaneously im...
journal_title:Neurosurgery
pub_type: 临床试验,杂志文章
doi:10.1227/01.neu.0000303993.82149.98
更新日期:2007-11-01 00:00:00
abstract:OBJECTIVE:Fifty percent of implanted cerebrospinal fluid (CSF) shunts fail within 2 years, primarily because of obstruction of the proximal catheter. Percutaneous techniques to reduce the morbidity of shunt revision are being developed. The authors describe the development of a device that uses ultrasonic cavitation to...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.NEU.0000233968.80352.25
更新日期:2006-10-01 00:00:00
abstract:OBJECTIVE:To analyze the incidence and impact of an intracerebral hematoma (ICH) on treatment and outcome in patients with aneurysmal subarachnoid hemorrhage. METHODS:Data of 585 consecutive patients with subarachnoid hemorrhage from June 1999 to December 2005 were prospectively entered in a database. ICH was diagnose...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.NEU.0000335170.76722.B9
更新日期:2008-12-01 00:00:00
abstract:OBJECTIVE:Fever is associated with worse outcome after subarachnoid hemorrhage, but there are few prospective data to quantify this relationship. METHODS:We prospectively enrolled consecutive aneurysmal or cryptogenic subarachnoid hemorrhage patients and recorded the highest core temperature each calendar day for Day ...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.NEU.0000320453.61270.0F
更新日期:2008-08-01 00:00:00
abstract::A rare case of primary spinal intramedullary malignant melanoma at the T6 level in a 31-year-old man is presented. The tumor was partially removed, and neuroaxis irradiation up to 50 Gy was then administered. Subsequently, systemic interferon beta (specific activity, 2.0 X 10(8) IU/mg protein) therapy (total dose, 2.2...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-198907000-00023
更新日期:1989-07-01 00:00:00