Abstract:
BACKGROUND:The etiology of morphea is still unknown. Borrelia spp. as a causative agent of morphea has been discussed since 1985, but the relationship remains uncertain. OBJECTIVES:We aimed to find the frequency of Borrelia in morphea lesions by polymerase chain reaction (PCR) in northeast of Iran. PATIENTS AND METHODS:Sixty six patients with morphea were prospectively included in the present study. For each patient, formalin-fixed, paraffin-embedded tissue blocks of skin lesion biopsies were examined for Borrelia spp. DNA using PCR. RESULTS:No Borrelia DNA was detected by PCR in skin lesions of patients with morphea. CONCLUSIONS:The result of this study showed no relationship between Borrelia infection and morphea lesions and in other word indicated that morphea, at least in Iran, is not caused by Borrelia spp.
journal_name
Jundishapur J Microbioljournal_title
Jundishapur journal of microbiologyauthors
Yazdanpanah MJ,Sharifi N,Khooei A,Banihashemi M,Khaje-Daluee M,Shamsi A,Ghazvini Kdoi
10.5812/jjm.19730v2subject
Has Abstractpub_date
2015-08-27 00:00:00pages
e19730issue
8eissn
2008-3645issn
2008-4161journal_volume
8pub_type
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