Frequency of Borrelia in Morphea Lesion by Polymerase Chain Reaction in Northeast of Iran.

Abstract:

BACKGROUND:The etiology of morphea is still unknown. Borrelia spp. as a causative agent of morphea has been discussed since 1985, but the relationship remains uncertain. OBJECTIVES:We aimed to find the frequency of Borrelia in morphea lesions by polymerase chain reaction (PCR) in northeast of Iran. PATIENTS AND METHODS:Sixty six patients with morphea were prospectively included in the present study. For each patient, formalin-fixed, paraffin-embedded tissue blocks of skin lesion biopsies were examined for Borrelia spp. DNA using PCR. RESULTS:No Borrelia DNA was detected by PCR in skin lesions of patients with morphea. CONCLUSIONS:The result of this study showed no relationship between Borrelia infection and morphea lesions and in other word indicated that morphea, at least in Iran, is not caused by Borrelia spp.

authors

Yazdanpanah MJ,Sharifi N,Khooei A,Banihashemi M,Khaje-Daluee M,Shamsi A,Ghazvini K

doi

10.5812/jjm.19730v2

subject

Has Abstract

pub_date

2015-08-27 00:00:00

pages

e19730

issue

8

eissn

2008-3645

issn

2008-4161

journal_volume

8

pub_type

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