Proteomics of pediatric heart failure: from traditional biomarkers to new discovery strategies.

Abstract:

:Heart failure in children is a complex clinical syndrome with multiple aetiologies. The underlying disorders that lead to heart failure in children differ significantly from those in adults. Some clinical biomarkers for heart failure status and prognosis appear to be useful in both age groups. This review outlines the use and the present status of biomarkers for heart failure in paediatric cardiology. Furthermore, clinical scenarios in which development of new biomarkers might address management or prognosis are discussed. Finally, strategies for proteomic discovery of novel biomarkers and application to practice are described.

journal_name

Cardiol Young

journal_title

Cardiology in the young

authors

Xu M,Ramirez-Correa GA,Murphy AM

doi

10.1017/S1047951115000839

subject

Has Abstract

pub_date

2015-08-01 00:00:00

pages

51-7

eissn

1047-9511

issn

1467-1107

pii

S1047951115000839

journal_volume

25 Suppl 2

pub_type

杂志文章,评审
  • Point-of-care pleural and lung ultrasound in a newborn suffering from cardiac arrest due to tension pneumothorax after cardiac surgery.

    abstract::We report the case of a 12-day-old newborn affected by coarctation of the aorta and intraventricular defect who underwent coarctectomy and pulmonary artery banding. On post-operative day 7, the patient suffered from pulseless electric activity due to tension pneumothorax. Point-of-care ultrasound was performed during ...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951115001213

    authors: Polito A,Biasucci DG,Cogo P

    更新日期:2016-02-01 00:00:00

  • Successful percutaneous transluminal coronary angioplasty for acute myocardial infarction in a 12-year-old boy with fibromuscular dysplasia: a case report.

    abstract::Acute myocardial infarction is rarely reported in children. Most of the cases are secondary to congenital anomalies or Kawasaki disease. Coronary artery total occlusion caused by fibromuscular dysplasia has never been reported in young children. Here we report a case of a 12-year-old boy with fibromuscular dysplasia, ...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951113002394

    authors: Lin MC,Lee WL,Fu YC

    更新日期:2015-01-01 00:00:00

  • Not just vegetations: focal myocardial changes in patients with fungal infections.

    abstract:BACKGROUND:Fungal endocarditis classically involves dense heterogenous vegetations. However, several patients with fungal infections were noted to have myocardial changes ranging from focal brightening to nodular thickening of chordae or papillary muscles. This study evaluates whether these findings are associated with...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951120003674

    authors: Cresalia NM,Owens ST,Stillwell TL,Norris MD,Yu S,Retzloff L,Ensing GJ

    更新日期:2020-11-13 00:00:00

  • Acute rheumatic fever in south-east of Turkey: clinical features and epidemiological evaluation of the patients over the last 25 years.

    abstract::This study evaluates clinical and epidemiological features of acute rheumatic fever using the data of last 25 years in our hospital in south-east of Turkey. The medical records of 377 patients with acute rheumatic fever admitted to Pediatric Cardiology Department of Çukurova University during 1993-2017 were retrospect...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951120001596

    authors: Erdem S,Demir F,Ayana M,Canan O,Okuducu YK,Arslan A,Kucukosmanoglu O,Özbarlas N

    更新日期:2020-08-01 00:00:00

  • Cardiac surgery in adults with high-surgical complexity CHD: results of a network collaborative programme.

    abstract:BACKGROUND:Adults with CHD often exhibit complex cardiac abnormalities, whose management requires specific clinical and surgical expertise. To enable easier access of these patients to highly specialised care, we implemented a collaborative programme that incorporates medical and surgical specialists belonging to both ...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951117001664

    authors: Gilad V,Santoro F,Ribera E,Calevo MG,Cipriani A,Pasquè A,Chierchia SL

    更新日期:2018-01-01 00:00:00

  • Kawasaki disease with tsutsugamushi disease: two case reports.

    abstract::A number of microorganisms were hypothesised as an aetiology of the Kawasaki disease. Unfortunately, no specific agent that provides reproducible evidence has yet been reported. We report two cases of extremely rare Kawasaki disease with tsutsugamushi disease. These case reports suggest that Kawasaki disease can rarel...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951120000931

    authors: Hwang HS,Kim YJ,Song MS

    更新日期:2020-06-01 00:00:00

  • Outcome of pregnancy in women with congenital heart disease.

    abstract::Improvements in diagnosis and surgical technique for correction have led to an increasing number of women with congenital heart disease reaching the child-bearing age. Pregnancy places considerable strain on the heart and circulation and necessitates marked cardiorespiratory adaptation. Today, with the exception of th...

    journal_title:Cardiology in the young

    pub_type: 杂志文章,评审

    doi:10.1017/s1047951100007496

    authors: Schmaltz AA,Neudorf U,Winkler UH

    更新日期:1999-01-01 00:00:00

  • Do toxic metals and trace elements have a role in the pathogenesis of conotruncal heart malformations?

    abstract:OBJECTIVE:The aim of the present study was to determine the role of toxic elements and trace elements in the pathogenesis of conotruncal heart defects by measuring their concentrations in the first meconium specimens of the affected newborns. METHODS:Concentrations of lead, cadmium, iron, zinc, and copper were measure...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951116000536

    authors: Kundak AA,Pektas A,Zenciroglu A,Ozdemir S,Barutcu UB,Orun UA,Okumus N

    更新日期:2017-03-01 00:00:00

  • The impact of the severity of disease and social disadvantage on quality of life in families with congenital cardiac disease.

    abstract:OBJECTIVE:Increasing rates of survival have raised the question of medical and psychosocial factors contributing to quality of life of patients with congenital cardiac disease. We investigated the impact of the severity of disease, and social disadvantage, on the quality of life of patients and their primary caregivers...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951105002118

    authors: Goldbeck L,Melches J

    更新日期:2006-02-01 00:00:00

  • Coronary sinus stenosis: an underdiagnosed cause for paediatric exertional chest pain.

    abstract::Undiagnosed coronary sinus obstruction can be a source of paediatric exertional chest pain and death. We present a case series of three interesting children who developed only exertional angina from various degrees of coronary sinus stenosis or atresia. We discuss the diagnosis and management of each case and the pote...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951120000918

    authors: Hegde SA,Moore J,Suarez WA

    更新日期:2020-06-01 00:00:00

  • Endocrinal complications associated with the treatment of patients with congenital cardiac disease: consensus definitions from the Multi-Societal Database Committee for Pediatric and Congenital Heart Disease.

    abstract::A complication is an event or occurrence that is associated with a disease or a healthcare intervention, is a departure from the desired course of events, and may cause, or be associated with, suboptimal outcome. A complication does not necessarily represent a breech in the standard of care that constitutes medical ne...

    journal_title:Cardiology in the young

    pub_type: 杂志文章,评审

    doi:10.1017/S1047951108002990

    authors: Dickerson H,Cooper DS,Checchia PA,Nelson DP

    更新日期:2008-12-01 00:00:00

  • Transcatheter pulmonary valve insertion: when, how, and why.

    abstract::Transcatheter pulmonary valve replacement is fast becoming an accepted alternative to repeat surgical pulmonary valve replacement for selected patients and therefore a complementary strategy in the long-term management of those requiring surgical pulmonary valve replacement. With a combined surgical and percutaneous a...

    journal_title:Cardiology in the young

    pub_type: 杂志文章,评审

    doi:10.1017/S1047951112001527

    authors: Ringewald JM,Suh EJ

    更新日期:2012-12-01 00:00:00

  • The REACH protocol: an innovative strategy for home management of infants with complex CHD.

    abstract::Approximately 32,000 infants are born with CHDs each year in the United States of America. Of every 1000 live births, 2.3 require surgical or transcatheter intervention in the first year of life. There are few more stressful times for parents than when their neonate receives a diagnosis of complex CHD requiring surger...

    journal_title:Cardiology in the young

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1017/S1047951118000604

    authors: Fleck DA,Marino BS,Costello JM,Ravishankar C,Torowicz D,Alden C,Van't Hof K,Medoff-Cooper B

    更新日期:2018-07-01 00:00:00

  • Clinical and pathophysiological aspects of bicuspid aortic valve disease.

    abstract::A bicuspid aortic valve is not only a common congenital heart defect but also an enigmatic condition that can cause a large spectrum of diseases, such as aortic valve stenosis and severe heart failure in newborns whereas aortic dissection in adults. On the contrary, a bicuspid aortic valve can also occur with normal f...

    journal_title:Cardiology in the young

    pub_type: 杂志文章,评审

    doi:10.1017/S1047951118001658

    authors: Pedersen MW,Groth KA,Mortensen KH,Brodersen J,Gravholt CH,Andersen NH

    更新日期:2019-01-01 00:00:00

  • Echocardiographic evaluation of cardiac structure and function in obese Egyptian adolescents.

    abstract:OBJECTIVE:The objective of this study was to detect structural and functional changes in the left and right ventricles in obese Egyptian adolescents. Methods and results Anthropometric and echocardiographic parameters, including tissue Doppler imaging, were obtained from 70 obese adolescents with average body mass inde...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951111001910

    authors: Kamal HM,Atwa HA,Saleh OM,Mohamed FA

    更新日期:2012-08-01 00:00:00

  • Rapid spontaneous closure and remodelling of a medium-sized symptomatic congenital coronary artery fistula in an infant before the age of 3 months.

    abstract::It is controversial to observe or close symptomatic congenital coronary artery fistula in infants. We herein describe a medium-sized symptomatic congenital coronary artery fistula that underwent rapid spontaneous closure in an infant aged <3 months. ...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951114001127

    authors: Lu WH,Huang TC,Hsieh KS

    更新日期:2015-04-01 00:00:00

  • Hybrid closure of a large atrial septal defect using Occlutech Flex II septal occluder in a patient with interrupted inferior caval vein.

    abstract::We present a case of a 31-year-old male with a large atrial septal defect, who was found to have interrupted inferior caval vein with azygous continuation to the superior caval vein, which precluded transcutaneous closure by device. The defect was successfully closed with a 33 mm Occlutech Figula septal occluder using...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S104795112000092X

    authors: Bani Hani A,Abdullattif M,Al-Ammouri I

    更新日期:2020-06-01 00:00:00

  • Factors prolonging length of stay in the cardiac intensive care unit following the arterial switch operation.

    abstract::The arterial switch operation has become the preferred procedure for surgical management of transposition, defined on the basis of concordant atrioventricular and discordant ventriculo-arterial connections. We conducted a retrospective evaluation of our experience in 61 infants with this segmental combination, seen fr...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951107001746

    authors: Wheeler DS,Dent CL,Manning PB,Nelson DP

    更新日期:2008-02-01 00:00:00

  • Pulmonary artery to left atrial fistula: haemodynamic changes traced from fetus to infancy until its interventional closure.

    abstract::Communications between the pulmonary artery and left atrium cause cyanosis. The images document serial haemodynamic changes in such a fistula from fetal life to the postnatal period with a successful transcatheter intervention. ...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951118000616

    authors: Sivakumar K,Sean DR

    更新日期:2018-10-01 00:00:00

  • Evolution of strategies for management of the patent arterial duct.

    abstract::Persistent patency of the arterial duct represents one of the most common lesions in the field of congenital cardiac disease. The strategies for management continue to evolve. In this review, we focus on management beyond the neonatal period. We review the temporal evolution of strategies for management, illustrate th...

    journal_title:Cardiology in the young

    pub_type: 杂志文章,评审

    doi:10.1017/S1047951107001175

    authors: Giroud JM,Jacobs JP

    更新日期:2007-09-01 00:00:00

  • What do we know about cognitive functioning in adult congenital heart disease?

    abstract::With the advent of improved medical and surgical care in congenital heart disease, there has been an increase in the number of patients who survive into adulthood, giving rise to a new patient population 'Adults with congenital heart disease'. In the past, morbidity and mortality were the primary concerns for this gro...

    journal_title:Cardiology in the young

    pub_type: 杂志文章,评审

    doi:10.1017/S1047951113000747

    authors: Tyagi M,Austin K,Stygall J,Deanfield J,Cullen S,Newman SP

    更新日期:2014-02-01 00:00:00

  • Percutaneous closure of ostium secundum atrial septal defect using left internal jugular vein access in a child with situs inversus and absence of inferior caval vein.

    abstract::Femoral vein access is the first choice for percutaneous atrial septal defect closure, and when it cannot be used due to anatomic reasons, the alternative sites should be considered, frequently increasing the complexity of the procedure. Here we report the case of a 3-year-old boy, with situs inversus and dextrocardia...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951119002099

    authors: Oliveira EC,Moura MAG,Almeida JA,Ribeiro ALP,Nascimento BR

    更新日期:2019-10-01 00:00:00

  • Massive systemic-to-pulmonary collateral arteries in the setting of a cavopulmonary shunt and pulmonary venous stenosis.

    abstract::We report a patient in whom a cavopulmonary anastomosis had been constructed, along with repair of anomalous pulmonary venous drainage. Left-sided pulmonary venous obstruction led to redistribution of the flow to the right lung. The reversal of flow in the left pulmonary artery was accentuated by flow through collater...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951107000960

    authors: Grosse-Wortmann L,Hamilton R,Yoo SJ

    更新日期:2007-10-01 00:00:00

  • Arch intervention following stage 1 palliation in hypoplastic left heart syndrome is associated with slower feed advancement: a report from the National Pediatric Quality Cardiology Improvement Collaborative.

    abstract:INTRODUCTION:Infants undergoing stage 1 palliation for hypoplastic left heart syndrome may have post-operative feeding difficulties. Although the cause of feeding difficulties in these patients is multi-factorial, residual arch obstruction may affect gut perfusion, contributing to feeding intolerance. We hypothesised t...

    journal_title:Cardiology in the young

    pub_type: 杂志文章,多中心研究

    doi:10.1017/S1047951120000177

    authors: Chaves AH,Baker-Smith CM,Rosenthal GL

    更新日期:2020-03-01 00:00:00

  • Plasmatic NT-proBNP could help to select cases for screening echocardiography in healthy infants with Respiratory Syncytial Virus infection.

    abstract::In Respiratory Syncytial Virus infection, the early identification of infants at risk for severe disease in order to potentially decrease morbidity could be considered a major goal. Current guidelines recommend only clinical observation for this purpose in infants without known comorbidities. However, recent evidence ...

    journal_title:Cardiology in the young

    pub_type: 信件

    doi:10.1017/S1047951119002348

    authors: Rodriguez-Gonzalez M,Benavente-Fernandez I,Castellano-Martinez A

    更新日期:2019-11-01 00:00:00

  • Percutaneous pulmonary valve implantation with the Venus P-valve: clinical experience and early results.

    abstract:BACKGROUND:At present, the exclusion for percutaneous pulmonary valve implantation for free pulmonary regurgitation after tetralogy of Fallot repair includes an unfavourably large right ventricular outflow tract. OBJECTIVE:To report feasibility and early experience with a recently developed transcatheter heart valve, ...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951115001067

    authors: Promphan W,Prachasilchai P,Siripornpitak S,Qureshi SA,Layangool T

    更新日期:2016-04-01 00:00:00

  • Treatment strategies for protein-losing enteropathy in Fontan-palliated patients.

    abstract:OBJECTIVE:Protein-losing enteropathy is an infrequent but severe condition occurring after Fontan procedure. The multifactorial pathogenesis remains unclear and no single proposed treatment strategy has proven universally successful. Therefore, we sought to describe different treatment strategies and their effect on cl...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951120000864

    authors: Schleiger A,Ovroutski S,Peters B,Schubert S,Photiadis J,Berger F,Kramer P

    更新日期:2020-05-01 00:00:00

  • Cardiac MRI T1 mapping in unrepaired anomalous left coronary artery from the pulmonary artery.

    abstract::A 29-year-old gravida1 para1 woman presented with increasing fatigue. Multi-modality imaging demonstrated the left coronary artery arising from the main pulmonary artery with large collateral vessels in the interventricular septum, in keeping with unrepaired anomalous left coronary artery from the pulmonary artery. Ca...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951117000932

    authors: Hanneman K,Wald R

    更新日期:2017-11-01 00:00:00

  • Current subjective state of health, and longitudinal psychological well-being over a period of 10 years, in a cohort of adults with congenital cardiac disease.

    abstract:OBJECTIVE:To examine the current subjective state of health, and the longitudinal course of psychological well-being, in adult patients with congenital cardiac malformations. METHODS:Our study concerns the second follow-up of a cohort of patients with congenital cardiac malformations. We examined 362 consecutive patie...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951105000351

    authors: van Rijen EH,Utens EM,Roos-Hesselink JW,Meijboom FJ,van Domburg RT,Roelandt JR,Bogers AJ,Verhulst FC

    更新日期:2005-04-01 00:00:00

  • Clinical and molecular characterisation of Holt-Oram syndrome focusing on cardiac manifestations.

    abstract:BACKGROUND:Holt-Oram syndrome is characterised by CHD and limb anomalies. Mutations in TBX5 gene, encoding the T-box transcription factor, are responsible for the development of Holt-Oram syndrome, but such mutations are variably detected in 30-75% of patients. METHODS:Clinically diagnosed eight Holt-Oram syndrome pat...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951114001656

    authors: Jhang WK,Lee BH,Kim GH,Lee JO,Yoo HW

    更新日期:2015-08-01 00:00:00