Abstract:
BACKGROUND:Fungal endocarditis classically involves dense heterogenous vegetations. However, several patients with fungal infections were noted to have myocardial changes ranging from focal brightening to nodular thickening of chordae or papillary muscles. This study evaluates whether these findings are associated with fungal infections. METHODS:In a retrospective case-control study, paediatric inpatients with fungal infections (positive blood, urine, or catheter tip culture) in a 5-year period were matched 1:1 to inpatients without positive fungal cultures. Echocardiograms were scored on a 5-point scale by two independent readers for presence of myocardial brightenings, nodular thickenings, and vegetations. Clinical data were compared. RESULTS:Of 67 fungal cases, positive culture sites included blood (n = 44), vascular catheter tip (n = 7), and urine (n = 29); several had multiple positive sites. "Positive" echo findings (score ≥ 2+) were more frequent in the Fungal Group (33 versus 18%, p = 0.04). Fungal Group patients with "positive" versus "negative" echo findings had similar proportion of bacterial infections. Among fungal cases, those with "positive" echo findings had longer hospital length of stay than cases with "negative" echos (median 58 versus 40 days, p = 0.03) but no difference in intensive care unit admission, extracorporeal membranous oxygenation support, or mortality. CONCLUSIONS:Myocardial and papillary muscle brightening with nodular thickening on echocardiogram appear to be associated with fungal infections. There may be prognostic implications of these findings as patients with "positive" echo have longer length of stay. Further studies are needed to better understand the mechanism and temporal progression of these changes and determine the prognostic value of this scoring system.
journal_name
Cardiol Youngjournal_title
Cardiology in the youngauthors
Cresalia NM,Owens ST,Stillwell TL,Norris MD,Yu S,Retzloff L,Ensing GJdoi
10.1017/S1047951120003674subject
Has Abstractpub_date
2020-11-13 00:00:00pages
1-6eissn
1047-9511issn
1467-1107pii
S1047951120003674pub_type
杂志文章abstract:OBJECTIVE:To evaluate the diagnosis, clinical features, management and post-natal follow-up in consecutive fetuses identified with tachycardia. METHODS:We reviewed consecutive fetuses with tachycardia identified in a single tertiary institution between January, 2001, and December, 2008. We considered several options f...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951109990497
更新日期:2009-09-01 00:00:00
abstract::Congenital stenosis of the pulmonary veins is a rare condition whose outcome is guarded despite the available treatment options. We report a case of a 6-month-old infant with significant stenosis of all four pulmonary veins. ...
journal_title:Cardiology in the young
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doi:10.1017/S1047951119000428
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abstract::Several surgical approaches for completion of a total cavopulmonary connection have been established for patients with anomalies of systemic venous connection in association with a functionally univentricular heart. We report an alternative technique designed to address the problem of widely separated inferior systemi...
journal_title:Cardiology in the young
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doi:10.1017/S1047951116001311
更新日期:2017-03-01 00:00:00
abstract::Our long-term follow-up has revealed that symmetrical development of the breasts is significantly impaired in pre-pubescent female patients subsequent to an anterolateral thoracotomy. Although standard posterolateral and anterolateral right-sided thoracotomies are used for correction of "simple" cardiac lesions such a...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:
更新日期:2003-12-01 00:00:00
abstract::We report an extremely rare case of a 14-month-old girl who was diagnosed with a single right coronary artery with coronary artery fistula communicating with the right ventricle and congenital absence of left coronary artery. Angiography showed a dilated and tortuous single right coronary artery draining into the righ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951119002105
更新日期:2019-11-01 00:00:00
abstract:UNLABELLED:Physical activity tends to be lower in school-age children with congenital heart disease than in healthy controls. To the best of our knowledge, objectively measured physical activity levels of preschool-age children with congenital heart disease have not been studied. METHODS:A total of 10 children with ei...
journal_title:Cardiology in the young
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doi:10.1017/S1047951114000298
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:The initial classic Fontan utilising a direct right atrial appendage to pulmonary artery anastomosis led to numerous complications. Adults with such complications may benefit from conversion to a total cavo-pulmonary connection, the current standard palliation for children with univentricular hearts. METHOD...
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更新日期:2019-08-01 00:00:00
abstract:BACKGROUND:Children with congenital cardiac disease experience challenges in developing healthy patterns of physical activity due to decreased exercise capacity and parental fear and confusion about what is permissible. The purpose of this study was to describe physical activity habits in children 10-14 years of age wi...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951111000540
更新日期:2011-12-01 00:00:00
abstract::CHD is associated with poor growth, delayed motor and language skills development, and increased length of hospital stay; 28.2% of infants were stunted, with z-scores<-2. The severity of surgery score was not associated with an increased length of stay, suggesting that a low weight-for-age z-score at the time of surge...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951115001778
更新日期:2016-04-01 00:00:00
abstract:PURPOSE:The aim of this study was to compare associations between generic versus disease-specific functional health status assessments and patient and clinical characteristics for patients with severe congenital heart disease. METHODS:This was a cross-sectional observational study involving 325 single ventricle patien...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951113000632
更新日期:2014-06-01 00:00:00
abstract::We describe the case of a 17-year-old male soccer player with T-wave inversion in precordial leads in resting electrocardiography, which also disclosed sinus bradycardia, early repolarization, and increased QRS voltage. These findings strongly suggested cardiomyopathy. The patient's T-wave inversion disappeared during...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951117001287
更新日期:2017-11-01 00:00:00
abstract::SummaryThe vast majority of patients with complete transposition present during either the neonatal period or early infancy. Almost always the diagnosis and the categorization of associated lesions can be established by cross-sectional echocardiography. Doppler techniques usually provide enough information about flows...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S104795110000007X
更新日期:1991-01-01 00:00:00
abstract::Endocarditis of congenital coronary fistulas in the cardiac chambers is rare, especially in the paediatric age group. We describe the case of a 9-year-old boy with a fistula from the dilated right coronary artery to the junction of the superior caval vein to the right atrium, complicated by endocarditis. Treatment con...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951117001846
更新日期:2018-02-01 00:00:00
abstract::Neonates and small infants have unique characteristics that make it possible to obtain echocardiographic views that are inaccessible in older patients. A high transsternal approach through the cartilaginous sternum and the thymus gland allows visualisation of a short-axis view of the pulmonary valve. This view should ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951115001845
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:To the best of our knowledge, normal limits of heart rate with respect to gender, and as established using 24-hour ambulatory Holter electrocardiography, have yet to be published for the entire age range of children and adolescents. OBJECTIVES:To establish the normal limits for heart rate in newborns, infan...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951108002539
更新日期:2008-10-01 00:00:00
abstract::Kawasaki disease constitutes an acute febrile vasculitis of unknown aetiology. It is considered the most common cause of acquired cardiac failure in children. Although standard treatment comprises intravenous immunoglobulin and aspirin, some children exhibit refractory disease, necessitating the use of alternative the...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951111001260
更新日期:2012-08-01 00:00:00
abstract::Myocardial ischaemia and infarction in pulmonary atresia and intact ventricular septum with right ventricular-dependent coronary circulation is a well-established complication. We report an interesting case of an acquired aneurysm in the ventricular septum in a patient who underwent staged palliation. ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951111001120
更新日期:2012-04-01 00:00:00
abstract::Myocarditis is an important cause of arrhythmogenic sudden cardiac arrest in the young. A strong index of suspicion is required as not only can arrhythmias be the only clinical manifestation but also because these patients can have normal cardiac biomarkers, electrocardiographic and echocardiographic findings, and inf...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951120001523
更新日期:2020-08-01 00:00:00
abstract::Heart failure in children is a complex clinical syndrome with multiple aetiologies. The underlying disorders that lead to heart failure in children differ significantly from those in adults. Some clinical biomarkers for heart failure status and prognosis appear to be useful in both age groups. This review outlines the...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/S1047951115000839
更新日期:2015-08-01 00:00:00
abstract:OBJECTIVES:The aim of the present study was to explore the predictive value of red cell distribution width as a means to differentiate between neurally mediated syncope and arrhythmic syncope in children. METHOD:Patients were divided into a neurally mediated syncope group (n=72) and an arrhythmic syncope group (n=21) ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951116001098
更新日期:2017-05-01 00:00:00
abstract::Gaucher disease is an autosomal-recessive lysosomal storage disease characterised by the accumulation of glucocerebroside in macrophages; it is caused by mutations in glucocerebrosidase gene-1 in many organ tissues such as the liver, spleen, and bone marrow. Its different clinical subtypes, according to the presence a...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/S1047951117000579
更新日期:2017-09-01 00:00:00
abstract::Anthracycline-related cardiomyopathy is of concern in children treated for acute myeloid leukemia (AML). Risk is dose-dependent, increasing with higher doses. We aim to highlight the risk of early-onset cardiotoxicity with low-cumulative anthracycline dose in a young Omani boy with AML. We conclude in the presence of ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951120003960
更新日期:2020-11-24 00:00:00
abstract::Primary vascular tumour of the heart is rare, especially in neonates and infants. We report a male premature newborn with a right atrial tumour associated with a large amount of pericardial effusion detected by screening foetal echography. Diagnosis of capillary haemangioma was confirmed by histopathological examinati...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951114002121
更新日期:2015-10-01 00:00:00
abstract::In approximately 5% of patients with idiopathic recurrent pericarditis, the disease usually follows a chronic relapsing course, and children can develop dependence and side effects of prolonged high-dose corticosteroid regimens. In this setting anakinra, a recombinant human interleukin-1 competitive receptor antagonis...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/S1047951118002020
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:The resection of a subaortic membrane remains far from a curative operation. We sought to examine factors associated with reoperation and the degree of aortic valve regurgitation as a potential long-term source for reoperation. METHODS:All patients who underwent resection of an isolated subaortic membrane b...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951119002336
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND:We have used the Amplatzer ductal occluder for transcatheter closure of large persistently patent arterial ducts, and used our experience to assess the safety and efficacy of the device in young children and infants. METHODS AND PATIENTS:We used the Amplatzer ductal occluder prospectively in 43 patients wit...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951105000570
更新日期:2005-06-01 00:00:00
abstract:INTRODUCTION:Infants undergoing stage 1 palliation for hypoplastic left heart syndrome may have post-operative feeding difficulties. Although the cause of feeding difficulties in these patients is multi-factorial, residual arch obstruction may affect gut perfusion, contributing to feeding intolerance. We hypothesised t...
journal_title:Cardiology in the young
pub_type: 杂志文章,多中心研究
doi:10.1017/S1047951120000177
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVE:To evaluate heart rate variability by Holter monitoring in type 1 diabetic children compared with a healthy control group and determine the factors modifying heart rate variability. METHODS:This was designed as a prospective study comparing 28 patients, diagnosed with type 1 diabetes and under follow-up, wit...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951113001224
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to determine developmental enamel defects and dental treatment conditions in children with congenital heart disease by comparing them with a control group of healthy children. METHODS:Children included in the study were referred to a paediatric dentistry for dental examination and t...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951113002308
更新日期:2015-02-01 00:00:00
abstract::Communications between the pulmonary artery and left atrium cause cyanosis. The images document serial haemodynamic changes in such a fistula from fetal life to the postnatal period with a successful transcatheter intervention. ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951118000616
更新日期:2018-10-01 00:00:00