Meta-analysis of Functional Neuroimaging of Major Depressive Disorder in Youth.

abstract：IMPORTANCE:Mental health (MH) conditions are undertreated in late life. It is important to identify treatment strategies that address variability in treatment content and delivery and take individual-specific symptoms into account, particularly among low-income, community-dwelling older adults. OBJECTIVE:To evaluate p...

journal_title：JAMA psychiatry

authors： Mavandadi S,Benson A,DiFilippo S,Streim JE,Oslin D

更新日期：2015-12-01 00:00:00

abstract：:IMPORTANCE—Suicide can be viewed as an escape from unendurable punishment at the cost of any future rewards. Could faulty estimation of these outcomes predispose to suicidal behavior? In behavioral studies, many of those who have attempted suicide misestimate expected rewards on gambling and probabilistic learning tas...

journal_title：JAMA psychiatry

authors： Dombrovski AY,Szanto K,Clark L,Reynolds CF,Siegle GJ

更新日期：2013-10-01 00:00:00

abstract：IMPORTANCE:Mood disorders and alcohol dependence frequently co-occur. Etiologic theories concerning the comorbidity often focus on drinking to self-medicate or cope with affective symptoms. However, there have been few, if any, prospective studies in population-based samples of alcohol self-medication of mood symptoms ...

journal_title：JAMA psychiatry

authors： Crum RM,Mojtabai R,Lazareck S,Bolton JM,Robinson J,Sareen J,Green KM,Stuart EA,La Flair L,Alvanzo AA,Storr CL

更新日期：2013-07-01 00:00:00

abstract：IMPORTANCE:The requirement of a childhood onset has always been a key criterion for the diagnosis of attention-deficit/hyperactivity disorder (ADHD) in adults, but recently this requirement has become surrounded by controversy. OBJECTIVE:To investigate whether impaired young adults with ADHD symptoms always have a chi...

journal_title：JAMA psychiatry

authors： Caye A,Rocha TB,Anselmi L,Murray J,Menezes AM,Barros FC,Gonçalves H,Wehrmeister F,Jensen CM,Steinhausen HC,Swanson JM,Kieling C,Rohde LA

更新日期：2016-07-01 00:00:00

abstract：IMPORTANCE:Serotonin is involved in negative affect, but whether anxiety syndromes, such as social anxiety disorder (SAD), are characterized by an overactive or underactive serotonin system has not been established. Serotonin 1A autoreceptors, which inhibit serotonin synthesis and release, are downregulated in SAD, and...

journal_title：JAMA psychiatry

authors： Frick A,Åhs F,Engman J,Jonasson M,Alaie I,Björkstrand J,Frans Ö,Faria V,Linnman C,Appel L,Wahlstedt K,Lubberink M,Fredrikson M,Furmark T

更新日期：2015-08-01 00:00:00

abstract：:Neural oscillations are rhythmic fluctuations over time in the activity or excitability of single neurons, local neuronal populations or "assemblies," and/or multiple regionally distributed neuronal assemblies. Synchronized oscillations among large numbers of neurons are evident in electrocorticographic, electroenceph...

journal_title：JAMA psychiatry

authors： Mathalon DH,Sohal VS

更新日期：2015-08-01 00:00:00

abstract：Importance:Autism spectrum disorder (ASD) is 2 to 5 times more common in male individuals than in female individuals. While the male preponderant prevalence of ASD might partially be explained by sex differences in clinical symptoms, etiological models suggest that the biological male phenotype carries a higher intrins...

journal_title：JAMA psychiatry

authors： Ecker C,Andrews DS,Gudbrandsen CM,Marquand AF,Ginestet CE,Daly EM,Murphy CM,Lai MC,Lombardo MV,Ruigrok AN,Bullmore ET,Suckling J,Williams SC,Baron-Cohen S,Craig MC,Murphy DG,Medical Research Council Autism Imaging Multice

更新日期：2017-04-01 00:00:00

abstract：IMPORTANCE:Anorexia nervosa (AN) is a serious disorder with high rates of morbidity and mortality. Family-based treatment (FBT) is an evidence-based therapy for adolescent AN, but less than half of those who receive this approach recover. Hence, it is important to identify other approaches to prevent the development of...

journal_title：JAMA psychiatry

authors： Agras WS,Lock J,Brandt H,Bryson SW,Dodge E,Halmi KA,Jo B,Johnson C,Kaye W,Wilfley D,Woodside B

更新日期：2014-11-01 00:00:00

abstract：IMPORTANCE:National epidemiologic information from recently collected data on the new DSM-5 classification of alcohol use disorder (AUD) using a reliable, valid, and uniform data source is needed. OBJECTIVE:To present nationally representative findings on the prevalence, correlates, psychiatric comorbidity, associated...

journal_title：JAMA psychiatry

authors： Grant BF,Goldstein RB,Saha TD,Chou SP,Jung J,Zhang H,Pickering RP,Ruan WJ,Smith SM,Huang B,Hasin DS

更新日期：2015-08-01 00:00:00

abstract：Importance:More effective, tolerable interventions for bipolar depression treatment are needed. Transcranial direct current stimulation (tDCS) is a novel therapeutic modality with few severe adverse events that showed promising results for unipolar depression. Objective:To determine the efficacy and safety of tDCS as ...

journal_title：JAMA psychiatry

authors： Sampaio-Junior B,Tortella G,Borrione L,Moffa AH,Machado-Vieira R,Cretaz E,Fernandes da Silva A,Fraguas R,Aparício LV,Klein I,Lafer B,Goerigk S,Benseñor IM,Lotufo PA,Gattaz WF,Brunoni AR

更新日期：2018-02-01 00:00:00

abstract：IMPORTANCE:The continuum view of the psychosis spectrum (PS) implies that, in population-based samples, PS symptoms should be associated with neural abnormalities similar to those found in help-seeking clinical risk individuals and in schizophrenia. To our knowledge, functional neuroimaging has not previously been appl...

journal_title：JAMA psychiatry

authors： Wolf DH,Satterthwaite TD,Calkins ME,Ruparel K,Elliott MA,Hopson RD,Jackson CT,Prabhakaran K,Bilker WB,Hakonarson H,Gur RC,Gur RE

更新日期：2015-05-01 00:00:00

abstract：Importance:Since the release of the DSM-5 diagnosis of attenuated psychosis syndrome (DSM-5-APS) in 2013, several research studies have investigated its clinical validity. Although critical and narrative reviews have reviewed these progresses, no systematic review has comprehensively summarized the available evidence r...

journal_title：JAMA psychiatry

authors： Salazar de Pablo G,Catalan A,Fusar-Poli P

更新日期：2020-03-01 00:00:00

abstract：IMPORTANCE:Adverse childhood experiences (ACEs) are associated with several adulthood health problems, such as self-directed violence. For some individuals, enlistment in the military may be an instrumental act to escape adverse household environments; however, to our knowledge prevalence of ACEs among persons with a h...

journal_title：JAMA psychiatry

authors： Blosnich JR,Dichter ME,Cerulli C,Batten SV,Bossarte RM

更新日期：2014-09-01 00:00:00

abstract：Importance:Several recent population-based studies have linked exposure to maternal smoking during pregnancy to increased risk of severe mental illness in offspring (eg, bipolar disorder, schizophrenia). It is not yet clear, however, whether this association results from causal teratogenic effects or from confounding i...

journal_title：JAMA psychiatry

authors： Quinn PD,Rickert ME,Weibull CE,Johansson ALV,Lichtenstein P,Almqvist C,Larsson H,Iliadou AN,D'Onofrio BM

更新日期：2017-06-01 00:00:00

abstract：Importance:The increase in deaths related to drugs, alcohol, and suicide (referred to as deaths from despair) has been identified as a public health crisis. The antecedents associated with these deaths have, however, seldom been investigated empirically. Objective:To prospectively examine the association between relig...

journal_title：JAMA psychiatry

authors： Chen Y,Koh HK,Kawachi I,Botticelli M,VanderWeele TJ

更新日期：2020-07-01 00:00:00

abstract：IMPORTANCE:In 1939, English mathematician, geneticist, and psychiatrist Lionel Sharples Penrose hypothesized that the numbers of psychiatric hospital beds and the sizes of prison populations were inversely related; 75 years later, the question arises as to whether the hypothesis applies to recent developments in South ...

journal_title：JAMA psychiatry

authors： Mundt AP,Chow WS,Arduino M,Barrionuevo H,Fritsch R,Girala N,Minoletti A,Mitkiewicz F,Rivera G,Tavares M,Priebe S

更新日期：2015-02-01 00:00:00

abstract：IMPORTANCE:Neurobiological models of obsessive-compulsive disorder (OCD) predict hyperactivity in brain circuits involving the orbitofrontal cortex and the basal ganglia, but it is unclear whether these areas are also characterized by altered brain network properties. OBJECTIVES:To determine regions of abnormal degree...

journal_title：JAMA psychiatry

authors： Beucke JC,Sepulcre J,Talukdar T,Linnman C,Zschenderlein K,Endrass T,Kaufmann C,Kathmann N

更新日期：2013-06-01 00:00:00

abstract：Importance:Depression is associated with increased inflammation, which may precede its onset, especially in older people. Some preclinical data suggest potential antidepressant effects of aspirin, supported by limited observational data suggesting lower rates of depression in individuals treated with aspirin. There cur...

journal_title：JAMA psychiatry

authors： Berk M,Woods RL,Nelson MR,Shah RC,Reid CM,Storey E,Fitzgerald S,Lockery JE,Wolfe R,Mohebbi M,Dodd S,Murray AM,Stocks N,Fitzgerald PB,Mazza C,Agustini B,McNeil JJ

更新日期：2020-10-01 00:00:00

abstract：IMPORTANCE:A major public health concern associated with schizophrenia and psychotic disorders is the long-term disability that involves impaired cognition, lack of social support, and an inability to function independently in the community. A critical goal of early detection and intervention studies in psychosis is th...

journal_title：JAMA psychiatry

authors： Carrión RE,McLaughlin D,Goldberg TE,Auther AM,Olsen RH,Olvet DM,Correll CU,Cornblatt BA

更新日期：2013-11-01 00:00:00

abstract：Importance:A relapse into nicotine addiction during abstinence often occurs after the reactivation of nicotine reward memories, either by acute exposure to nicotine (a smoking episode) or by smoking-associated conditioned stimuli (CS). Preclinical studies suggest that drug reward memories can undergo memory reconsolida...

journal_title：JAMA psychiatry

authors： Xue YX,Deng JH,Chen YY,Zhang LB,Wu P,Huang GD,Luo YX,Bao YP,Wang YM,Shaham Y,Shi J,Lu L

更新日期：2017-03-01 00:00:00

abstract：IMPORTANCE:Twin-family studies have shown that parent-child resemblance on substance use disorders and antisocial behavior can be accounted for by the transmission of a general liability to a spectrum of externalizing disorders. Most studies, however, include only biological parents and offspring, which confound geneti...

journal_title：JAMA psychiatry

authors： Hicks BM,Foster KT,Iacono WG,McGue M

更新日期：2013-10-01 00:00:00

abstract：Importance:Because more than one-third of people making nonfatal suicide attempts do not receive mental health treatment, it is essential to extend suicide attempt risk factors beyond high-risk clinical populations to the general adult population. Objective:To identify future suicide attempt risk factors in the genera...

journal_title：JAMA psychiatry

authors： García de la Garza Á,Blanco C,Olfson M,Wall MM

更新日期：2021-01-06 00:00:00

abstract：IMPORTANCE:The neural systems that confer risk or vulnerability for developing familial depression, and those that protect against or confer resilience to becoming ill, can be disentangled from the effects of prior illness by comparing brain imaging measures in previously ill and never ill persons who have either a hig...

journal_title：JAMA psychiatry

authors： Peterson BS,Wang Z,Horga G,Warner V,Rutherford B,Klahr KW,Graniello B,Wickramaratne P,Garcia F,Yu S,Hao X,Adams PB,Qian M,Liu J,Gerber A,Weissman MM

更新日期：2014-02-01 00:00:00

abstract：IMPORTANCE:Some, but not all, previous magnetic resonance imaging studies have indicated smaller cortical and local gray matter volumes (GMVs) in men with schizotypal personality disorder (SPD) compared with healthy control (HC) subjects. Thus, there is need for a whole-brain comparison to resolve inconsistencies and p...

journal_title：JAMA psychiatry

authors： Asami T,Whitford TJ,Bouix S,Dickey CC,Niznikiewicz M,Shenton ME,Voglmaier MM,McCarley RW

更新日期：2013-04-01 00:00:00

abstract：IMPORTANCE:Depression and obesity are 2 prevalent disorders that have been repeatedly shown to be associated. However, the mechanisms and temporal sequence underlying this association are poorly understood. OBJECTIVE:To determine whether the subtypes of major depressive disorder (MDD; melancholic, atypical, combined, ...

journal_title：JAMA psychiatry

authors： Lasserre AM,Glaus J,Vandeleur CL,Marques-Vidal P,Vaucher J,Bastardot F,Waeber G,Vollenweider P,Preisig M

更新日期：2014-08-01 00:00:00

abstract：Importance:Major depressive disorder (MDD) might involve dopamine (DA) reductions. The DA transporter (DAT) regulates DA clearance and neurotransmission and is sensitive to DA levels, with preclinical studies (including those involving inescapable stressors) showing that DAT density decreases when DA signaling is reduc...

journal_title：JAMA psychiatry

authors： Pizzagalli DA,Berretta S,Wooten D,Goer F,Pilobello KT,Kumar P,Murray L,Beltzer M,Boyer-Boiteau A,Alpert N,El Fakhri G,Mechawar N,Vitaliano G,Turecki G,Normandin M

更新日期：2019-08-01 00:00:00

abstract：IMPORTANCE:Cocaine dependence is a significant public health problem, yet no validated pharmacological treatment exists. The potent γ-aminobutyric acid (GABA)ergic medication vigabatrin has previously been shown to be effective in a double-blind single-site study conducted in Mexico. OBJECTIVE:To evaluate the safety a...

journal_title：JAMA psychiatry

authors： Somoza EC,Winship D,Gorodetzky CW,Lewis D,Ciraulo DA,Galloway GP,Segal SD,Sheehan M,Roache JD,Bickel WK,Jasinski D,Watson DW,Miller SR,Somoza P,Winhusen T

更新日期：2013-06-01 00:00:00

abstract：Importance:Little is known about changes in marijuana use and cannabis use disorder (CUD) after recreational marijuana legalization (RML). Objectives:To examine the associations between RML enactment and changes in marijuana use, frequent use, and CUD in the United States from 2008 to 2016. Design, Setting, and Parti...

journal_title：JAMA psychiatry

authors： Cerdá M,Mauro C,Hamilton A,Levy NS,Santaella-Tenorio J,Hasin D,Wall MM,Keyes KM,Martins SS

更新日期：2020-02-01 00:00:00

abstract：IMPORTANCE:Genome-wide investigations provide systematic information regarding the neurobiology of psychiatric disorders. OBJECTIVE:To identify biological pathways that contribute to risk for bipolar disorder (BP) using genes with consistent evidence for association in multiple genome-wide association studies (GWAS). ...

journal_title：JAMA psychiatry

authors： Nurnberger JI Jr,Koller DL,Jung J,Edenberg HJ,Foroud T,Guella I,Vawter MP,Kelsoe JR,Psychiatric Genomics Consortium Bipolar Group.

更新日期：2014-06-01 00:00:00

abstract：Importance:Autism spectrum disorder (ASD) is a highly prevalent disorder, and community psychiatrists are likely to treat many individuals with ASD during their clinical practice. This clinical case challenge describes a routine evaluation of irritability and self-injury in a preschool-aged child who meets the criteria...

journal_title：JAMA psychiatry

authors： Muhle RA,Reed HE,Stratigos KA,Veenstra-VanderWeele J

更新日期：2018-05-01 00:00:00