The Need for Innovation in Health Care Systems to Improve Suicide Prevention.

abstract：IMPORTANCE:Although high rates of current mental disorder are known to exist in the US Army, little is known about the proportions of these disorders that had onsets prior to enlistment. OBJECTIVE:To estimate the proportions of 30-day DSM-IV mental disorders among nondeployed US Army personnel with first onsets prior ...

journal_title：JAMA psychiatry

authors： Kessler RC,Heeringa SG,Stein MB,Colpe LJ,Fullerton CS,Hwang I,Naifeh JA,Nock MK,Petukhova M,Sampson NA,Schoenbaum M,Zaslavsky AM,Ursano RJ,Army STARRS Collaborators.

更新日期：2014-05-01 00:00:00

abstract：Importance:Tobacco use disorder is associated with dysregulated neurocognitive function in the right inferior frontal gyrus (IFG)-one node in a corticothalamic inhibitory control (IC) network. Objective:To examine associations between IC neural circuitry structure and function and lapse/relapse vulnerability in 2 inde...

journal_title：JAMA psychiatry

authors： Froeliger B,McConnell PA,Bell S,Sweitzer M,Kozink RV,Eichberg C,Hallyburton M,Kaiser N,Gray KM,McClernon FJ

更新日期：2017-04-01 00:00:00

abstract：Importance:Several psychotherapy protocols have been evaluated as adjuncts to pharmacotherapy for patients with bipolar disorder, but little is known about their comparative effectiveness. Objective:To use systematic review and network meta-analysis to compare the association of using manualized psychotherapies and th...

journal_title：JAMA psychiatry

authors： Miklowitz DJ,Efthimiou O,Furukawa TA,Scott J,McLaren R,Geddes JR,Cipriani A

更新日期：2020-10-14 00:00:00

abstract：IMPORTANCE:Freud argued that in conversion disorder (CD) the affect attached to stressful memories is "repressed" and "converted" into physical symptoms, although this has never been subject to scientific study to our knowledge. OBJECTIVE:To examine the neural correlates of recall of life events judged to be of causal...

journal_title：JAMA psychiatry

authors： Aybek S,Nicholson TR,Zelaya F,O'Daly OG,Craig TJ,David AS,Kanaan RA

更新日期：2014-01-01 00:00:00

abstract：Importance:Dysfunctional reward processing is a leading candidate mechanism for the development of certain depressive symptoms, such as anhedonia. However, to our knowledge, there has not yet been a systematic assessment of whether and to what extent depression is associated with impairments on behavioral reward-proces...

journal_title：JAMA psychiatry

authors： Halahakoon DC,Kieslich K,O'Driscoll C,Nair A,Lewis G,Roiser JP

更新日期：2020-07-29 00:00:00

abstract：Importance:The onset of adult psychopathologic disorders can be traced to behavioral or emotional symptoms observed in childhood, which could be targeted in early interventions to prevent future mental disorders. The network perspective is a novel conceptualization of psychopathologic disorders that could help to ident...

journal_title：JAMA psychiatry

authors： Rouquette A,Pingault JB,Fried EI,Orri M,Falissard B,Kossakowski JJ,Vitaro F,Tremblay R,Cote SM,Borsboom D

更新日期：2018-11-01 00:00:00

abstract：IMPORTANCE:Psychotic persons who are violent often explain their violence as being due to delusions. However, research has failed to confirm associations between delusions and violent behavior. OBJECTIVES:To investigate which delusional beliefs and characteristics are associated with violent behavior during a first ep...

journal_title：JAMA psychiatry

authors： Coid JW,Ullrich S,Kallis C,Keers R,Barker D,Cowden F,Stamps R

更新日期：2013-05-01 00:00:00

abstract：:CONTEXT Clinical experience and factor analytic studies suggest that some psychiatric disorders may be more closely related to one another, as indicated by the frequency of their co-occurrence, which may have etiologic and treatment implications. OBJECTIVE To construct a virtual space of common psychiatric disorders, ...

journal_title：JAMA psychiatry

authors： Blanco C,Krueger RF,Hasin DS,Liu SM,Wang S,Kerridge BT,Saha T,Olfson M

更新日期：2013-02-01 00:00:00

abstract：Importance:Depression is associated with increased inflammation, which may precede its onset, especially in older people. Some preclinical data suggest potential antidepressant effects of aspirin, supported by limited observational data suggesting lower rates of depression in individuals treated with aspirin. There cur...

journal_title：JAMA psychiatry

authors： Berk M,Woods RL,Nelson MR,Shah RC,Reid CM,Storey E,Fitzgerald S,Lockery JE,Wolfe R,Mohebbi M,Dodd S,Murray AM,Stocks N,Fitzgerald PB,Mazza C,Agustini B,McNeil JJ

更新日期：2020-10-01 00:00:00

abstract：IMPORTANCE:The neural systems that confer risk or vulnerability for developing familial depression, and those that protect against or confer resilience to becoming ill, can be disentangled from the effects of prior illness by comparing brain imaging measures in previously ill and never ill persons who have either a hig...

journal_title：JAMA psychiatry

authors： Peterson BS,Wang Z,Horga G,Warner V,Rutherford B,Klahr KW,Graniello B,Wickramaratne P,Garcia F,Yu S,Hao X,Adams PB,Qian M,Liu J,Gerber A,Weissman MM

更新日期：2014-02-01 00:00:00

abstract：Importance:Because more than one-third of people making nonfatal suicide attempts do not receive mental health treatment, it is essential to extend suicide attempt risk factors beyond high-risk clinical populations to the general adult population. Objective:To identify future suicide attempt risk factors in the genera...

journal_title：JAMA psychiatry

authors： García de la Garza Á,Blanco C,Olfson M,Wall MM

更新日期：2021-01-06 00:00:00

abstract：:IMPORTANCE—Suicide can be viewed as an escape from unendurable punishment at the cost of any future rewards. Could faulty estimation of these outcomes predispose to suicidal behavior? In behavioral studies, many of those who have attempted suicide misestimate expected rewards on gambling and probabilistic learning tas...

journal_title：JAMA psychiatry

authors： Dombrovski AY,Szanto K,Clark L,Reynolds CF,Siegle GJ

更新日期：2013-10-01 00:00:00

abstract：IMPORTANCE:Fragile X syndrome (FXS) is an X-linked neurogenetic disorder characterized by a cognitive and behavioral phenotype resembling features of autism spectrum disorder. Until now, research has focused largely on identifying regional differences in brain structure and function between individuals with FXS and var...

journal_title：JAMA psychiatry

authors： Hall SS,Jiang H,Reiss AL,Greicius MD

更新日期：2013-11-01 00:00:00

abstract：Importance:More effective, tolerable interventions for bipolar depression treatment are needed. Transcranial direct current stimulation (tDCS) is a novel therapeutic modality with few severe adverse events that showed promising results for unipolar depression. Objective:To determine the efficacy and safety of tDCS as ...

journal_title：JAMA psychiatry

authors： Sampaio-Junior B,Tortella G,Borrione L,Moffa AH,Machado-Vieira R,Cretaz E,Fernandes da Silva A,Fraguas R,Aparício LV,Klein I,Lafer B,Goerigk S,Benseñor IM,Lotufo PA,Gattaz WF,Brunoni AR

更新日期：2018-02-01 00:00:00

abstract：Importance:Autism spectrum disorder (ASD) is a highly prevalent disorder, and community psychiatrists are likely to treat many individuals with ASD during their clinical practice. This clinical case challenge describes a routine evaluation of irritability and self-injury in a preschool-aged child who meets the criteria...

journal_title：JAMA psychiatry

authors： Muhle RA,Reed HE,Stratigos KA,Veenstra-VanderWeele J

更新日期：2018-05-01 00:00:00

abstract：Importance:Suicide is a public health problem, with multiple causes that are poorly understood. The increased focus on combining health care data with machine-learning approaches in psychiatry may help advance the understanding of suicide risk. Objective:To examine sex-specific risk profiles for death from suicide usi...

journal_title：JAMA psychiatry

authors： Gradus JL,Rosellini AJ,Horváth-Puhó E,Street AE,Galatzer-Levy I,Jiang T,Lash TL,Sørensen HT

更新日期：2020-01-01 00:00:00

abstract：IMPORTANCE:In schizophrenia, working memory deficits appear to reflect abnormalities in the generation of gamma oscillations in the dorsolateral prefrontal cortex. The generation of gamma oscillations requires the phasic excitation of inhibitory parvalbumin-containing interneurons. Thus, gamma oscillations depend, in p...

journal_title：JAMA psychiatry

authors： Kimoto S,Zaki MM,Bazmi HH,Lewis DA

更新日期：2015-08-01 00:00:00

abstract：IMPORTANCE:Community functioning is a core component of the functional deficits in schizophrenia, yet little systematic research on the origins of these functional deficits has been performed. OBJECTIVES:To examine 3 key domains of community functioning--social activity, independent behavior, and functioning in school...

journal_title：JAMA psychiatry

authors： Velthorst E,Reichenberg A,Kapra O,Goldberg S,Fromer M,Fruchter E,Ginat K,de Haan L,Davidson M,Weiser M

更新日期：2016-01-01 00:00:00

abstract：Importance:Substance abuse preventive interventions frequently target middle school students and demonstrate efficacy to prevent early onset and use of alcohol and illicit drugs. However, evidence of sustained results to prevent later patterns of alcohol misuse and more serious alcohol abuse disorders has been lacking,...

journal_title：JAMA psychiatry

authors： Gonzales NA,Jensen M,Tein JY,Wong JJ,Dumka LE,Mauricio AM

更新日期：2018-05-01 00:00:00

abstract：IMPORTANCE:Developmental brain disorders are a group of clinically and genetically heterogeneous disorders characterized by high heritability. Specific highly penetrant genetic causes can often be shared by a subset of individuals with different phenotypic features, and recent advances in genome sequencing have allowed...

journal_title：JAMA psychiatry

authors： Gonzalez-Mantilla AJ,Moreno-De-Luca A,Ledbetter DH,Martin CL

更新日期：2016-03-01 00:00:00

abstract：Importance:In light of increasing cannabis use among pregnant women, the US Surgeon General recently issued an advisory against the use of marijuana during pregnancy. Objective:To evaluate whether cannabis use during pregnancy is associated with adverse outcomes among offspring. Design, Setting, and Participants:In t...

journal_title：JAMA psychiatry

authors： Paul SE,Hatoum AS,Fine JD,Johnson EC,Hansen I,Karcher NR,Moreau AL,Bondy E,Qu Y,Carter EB,Rogers CE,Agrawal A,Barch DM,Bogdan R

更新日期：2021-01-01 00:00:00

abstract：Importance:Altered neurodevelopmental trajectories are thought to reflect heterogeneity in the pathophysiologic characteristics of schizophrenia, but whether neural indicators of these trajectories are associated with future psychosis is unclear. Objective:To investigate distinct neuroanatomical markers that can diffe...

journal_title：JAMA psychiatry

authors： Chung Y,Addington J,Bearden CE,Cadenhead K,Cornblatt B,Mathalon DH,McGlashan T,Perkins D,Seidman LJ,Tsuang M,Walker E,Woods SW,McEwen S,van Erp TGM,Cannon TD,North American Prodrome Longitudinal Study (NAPLS) Consortium and

更新日期：2018-09-01 00:00:00

abstract：IMPORTANCE:Whether traumatic brain injury (TBI) is a risk factor for posttraumatic stress disorder (PTSD) has been difficult to determine because of the prevalence of comorbid conditions, overlapping symptoms, and cross-sectional samples. OBJECTIVE:To examine the extent to which self-reported predeployment and deploym...

journal_title：JAMA psychiatry

authors： Yurgil KA,Barkauskas DA,Vasterling JJ,Nievergelt CM,Larson GE,Schork NJ,Litz BT,Nash WP,Baker DG,Marine Resiliency Study Team.

更新日期：2014-02-01 00:00:00

abstract：Importance:Publicly funded mental health services play an important role in addressing co-occurring mental health problems in children with autism spectrum disorder (ASD); however, therapists report lacking training to effectively serve this complex population. Objective:To test the effectiveness of training community...

journal_title：JAMA psychiatry

authors： Brookman-Frazee L,Roesch S,Chlebowski C,Baker-Ericzen M,Ganger W

更新日期：2019-06-01 00:00:00

abstract：Importance:There has been limited systematic examination of whether risk of suicide attempt (SA) among US Army soldiers is associated with time-related deployment variables, such as time in service before first deployment, duration of first deployment, and dwell time (DT) (ie, length of time between deployments). Obje...

journal_title：JAMA psychiatry

authors： Ursano RJ,Kessler RC,Naifeh JA,Herberman Mash H,Fullerton CS,Aliaga PA,Wynn GH,Ng THH,Dinh HM,Sampson NA,Kao TC,Bliese PD,Stein MB

更新日期：2018-06-01 00:00:00

abstract：Importance:Autism spectrum disorder (ASD) is 2 to 5 times more common in male individuals than in female individuals. While the male preponderant prevalence of ASD might partially be explained by sex differences in clinical symptoms, etiological models suggest that the biological male phenotype carries a higher intrins...

journal_title：JAMA psychiatry

authors： Ecker C,Andrews DS,Gudbrandsen CM,Marquand AF,Ginestet CE,Daly EM,Murphy CM,Lai MC,Lombardo MV,Ruigrok AN,Bullmore ET,Suckling J,Williams SC,Baron-Cohen S,Craig MC,Murphy DG,Medical Research Council Autism Imaging Multice

更新日期：2017-04-01 00:00:00

abstract：Importance:Preeclampsia during pregnancy has been linked to an increased risk of cerebral palsy in offspring. Less is known about the role of preeclampsia in other neurodevelopmental disorders. Objective:To determine the association between preeclampsia and a range of adverse neurodevelopmental outcomes in offspring a...

journal_title：JAMA psychiatry

authors： Sun BZ,Moster D,Harmon QE,Wilcox AJ

更新日期：2020-08-01 00:00:00

abstract：Importance:Deviation from normal adolescent brain development precedes manifestations of many major psychiatric symptoms. Such altered developmental trajectories in adolescents may be linked to genetic risk for psychopathology. Objective:To identify genetic variants associated with adolescent brain structure and explo...

journal_title：JAMA psychiatry

authors： Luo Q,Chen Q,Wang W,Desrivières S,Quinlan EB,Jia T,Macare C,Robert GH,Cui J,Guedj M,Palaniyappan L,Kherif F,Banaschewski T,Bokde ALW,Büchel C,Flor H,Frouin V,Garavan H,Gowland P,Heinz A,Ittermann B,Martinot JL,

更新日期：2019-04-01 00:00:00

abstract：:CONTEXT Suicide bereavement remains understudied and poorly understood. OBJECTIVES To examine outcomes of parents bereaved by the suicide death of their offspring and to compare these with both nonbereaved parent controls and parents who had offspring die in a motor vehicle crash (MVC). DESIGN Population-based case-co...

journal_title：JAMA psychiatry

authors： Bolton JM,Au W,Leslie WD,Martens PJ,Enns MW,Roos LL,Katz LY,Wilcox HC,Erlangsen A,Chateau D,Walld R,Spiwak R,Seguin M,Shear K,Sareen J

更新日期：2013-02-01 00:00:00

abstract：IMPORTANCE:Alterations in glutamatergic neurotransmission have been postulated to be a key pathophysiologic mechanism in schizophrenia. OBJECTIVE:To evaluate hippocampal volumetric measures and neurometabolites in unmedicated patients with schizophrenia and the correlations between these markers. Our a priori hypothes...

journal_title：JAMA psychiatry

authors： Kraguljac NV,White DM,Reid MA,Lahti AC

更新日期：2013-12-01 00:00:00