Association Between Baseline Corticothalamic-Mediated Inhibitory Control and Smoking Relapse Vulnerability.

abstract：IMPORTANCE:Brain imaging studies have identified robust changes in brain structure and function during the development of psychosis, but the contribution of abnormal brain connectivity to the onset of psychosis is unclear. Furthermore, antipsychotic treatment can modulate brain activity and functional connectivity duri...

journal_title：JAMA psychiatry

authors： Schmidt A,Smieskova R,Aston J,Simon A,Allen P,Fusar-Poli P,McGuire PK,Riecher-Rössler A,Stephan KE,Borgwardt S

更新日期：2013-09-01 00:00:00

abstract：IMPORTANCE:Studies have shown that the scientific literature has overestimated the efficacy of antidepressants for depression, but other indications for these drugs have not been considered. OBJECTIVE:To examine reporting biases in double-blind, placebo-controlled trials on the pharmacologic treatment of anxiety disor...

journal_title：JAMA psychiatry

authors： Roest AM,de Jonge P,Williams CD,de Vries YA,Schoevers RA,Turner EH

更新日期：2015-05-01 00:00:00

abstract：Importance:Publicly funded mental health services play an important role in addressing co-occurring mental health problems in children with autism spectrum disorder (ASD); however, therapists report lacking training to effectively serve this complex population. Objective:To test the effectiveness of training community...

journal_title：JAMA psychiatry

authors： Brookman-Frazee L,Roesch S,Chlebowski C,Baker-Ericzen M,Ganger W

更新日期：2019-06-01 00:00:00

abstract：Importance:Epidemiologic evidence indicates that most of the general population will experience a mental health disorder at some point in their lives. However, few prospective population-based studies have estimated trajectories of risk for mental disorders from young through middle adulthood to estimate the proportion...

journal_title：JAMA psychiatry

authors： Paksarian D,Cui L,Angst J,Ajdacic-Gross V,Rössler W,Merikangas KR

更新日期：2016-10-01 00:00:00

abstract：IMPORTANCE:Cannabis dependence (CAD) is a serious problem worldwide and is of growing importance in the United States because cannabis is increasingly available legally. Although genetic factors contribute substantially to CAD risk, at present no well-established specific genetic risk factors for CAD have been elucidat...

journal_title：JAMA psychiatry

authors： Sherva R,Wang Q,Kranzler H,Zhao H,Koesterer R,Herman A,Farrer LA,Gelernter J

更新日期：2016-05-01 00:00:00

abstract：IMPORTANCE:Animal data suggest that chronic stress is associated with a reduction in norepinephrine transporter (NET) availability in the locus coeruleus. However, it is unclear whether such models are relevant to posttraumatic stress disorder (PTSD), which has been linked to noradrenergic dysfunction in humans. OBJEC...

journal_title：JAMA psychiatry

authors： Pietrzak RH,Gallezot JD,Ding YS,Henry S,Potenza MN,Southwick SM,Krystal JH,Carson RE,Neumeister A

更新日期：2013-11-01 00:00:00

abstract：IMPORTANCE:The structural abnormalities in the brain that accurately differentiate unipolar depression (UD) and bipolar depression (BD) remain unidentified. OBJECTIVES:First, to investigate and compare morphometric changes in UD and BD, and to replicate the findings at 2 independent neuroimaging sites; second, to diff...

journal_title：JAMA psychiatry

authors： Redlich R,Almeida JJ,Grotegerd D,Opel N,Kugel H,Heindel W,Arolt V,Phillips ML,Dannlowski U

更新日期：2014-11-01 00:00:00

abstract：Importance:Cognitive impairment occurs across the psychosis spectrum and is associated with functional outcome. However, it is unknown whether these shared manifestations of cognitive dysfunction across diagnostic categories also reflect shared neurobiological mechanisms or whether the source of impairment differs. Ob...

journal_title：JAMA psychiatry

authors： Sheffield JM,Kandala S,Tamminga CA,Pearlson GD,Keshavan MS,Sweeney JA,Clementz BA,Lerman-Sinkoff DB,Hill SK,Barch DM

更新日期：2017-06-01 00:00:00

abstract：Importance:Deviation from normal adolescent brain development precedes manifestations of many major psychiatric symptoms. Such altered developmental trajectories in adolescents may be linked to genetic risk for psychopathology. Objective:To identify genetic variants associated with adolescent brain structure and explo...

journal_title：JAMA psychiatry

authors： Luo Q,Chen Q,Wang W,Desrivières S,Quinlan EB,Jia T,Macare C,Robert GH,Cui J,Guedj M,Palaniyappan L,Kherif F,Banaschewski T,Bokde ALW,Büchel C,Flor H,Frouin V,Garavan H,Gowland P,Heinz A,Ittermann B,Martinot JL,

更新日期：2019-04-01 00:00:00

abstract：Importance:Altered neurodevelopmental trajectories are thought to reflect heterogeneity in the pathophysiologic characteristics of schizophrenia, but whether neural indicators of these trajectories are associated with future psychosis is unclear. Objective:To investigate distinct neuroanatomical markers that can diffe...

journal_title：JAMA psychiatry

authors： Chung Y,Addington J,Bearden CE,Cadenhead K,Cornblatt B,Mathalon DH,McGlashan T,Perkins D,Seidman LJ,Tsuang M,Walker E,Woods SW,McEwen S,van Erp TGM,Cannon TD,North American Prodrome Longitudinal Study (NAPLS) Consortium and

更新日期：2018-09-01 00:00:00

abstract：IMPORTANCE:Cocaine addiction is associated with altered resting-state functional connectivity among regions of the mesocorticolimbic dopamine pathways. Methylphenidate hydrochloride, an indirect dopamine agonist, normalizes task-related regional brain activity and associated behavior in cocaine users; however, the neur...

journal_title：JAMA psychiatry

authors： Konova AB,Moeller SJ,Tomasi D,Volkow ND,Goldstein RZ

更新日期：2013-08-01 00:00:00

abstract：Importance:Dysfunctional reward processing is a leading candidate mechanism for the development of certain depressive symptoms, such as anhedonia. However, to our knowledge, there has not yet been a systematic assessment of whether and to what extent depression is associated with impairments on behavioral reward-proces...

journal_title：JAMA psychiatry

authors： Halahakoon DC,Kieslich K,O'Driscoll C,Nair A,Lewis G,Roiser JP

更新日期：2020-07-29 00:00:00

abstract：IMPORTANCE:In 1939, English mathematician, geneticist, and psychiatrist Lionel Sharples Penrose hypothesized that the numbers of psychiatric hospital beds and the sizes of prison populations were inversely related; 75 years later, the question arises as to whether the hypothesis applies to recent developments in South ...

journal_title：JAMA psychiatry

authors： Mundt AP,Chow WS,Arduino M,Barrionuevo H,Fritsch R,Girala N,Minoletti A,Mitkiewicz F,Rivera G,Tavares M,Priebe S

更新日期：2015-02-01 00:00:00

abstract：Importance:Recent estimates suggest that more than 50% of all deaths worldwide are currently attributable to inflammation-related diseases. Psychosocial interventions may represent a potentially useful strategy for addressing this global public health problem, but which types of interventions reliably improve immune sy...

journal_title：JAMA psychiatry

authors： Shields GS,Spahr CM,Slavich GM

更新日期：2020-10-01 00:00:00

abstract：IMPORTANCE:Depression and obesity are 2 prevalent disorders that have been repeatedly shown to be associated. However, the mechanisms and temporal sequence underlying this association are poorly understood. OBJECTIVE:To determine whether the subtypes of major depressive disorder (MDD; melancholic, atypical, combined, ...

journal_title：JAMA psychiatry

authors： Lasserre AM,Glaus J,Vandeleur CL,Marques-Vidal P,Vaucher J,Bastardot F,Waeber G,Vollenweider P,Preisig M

更新日期：2014-08-01 00:00:00

abstract：IMPORTANCE:Adverse childhood experiences (ACEs) are associated with several adulthood health problems, such as self-directed violence. For some individuals, enlistment in the military may be an instrumental act to escape adverse household environments; however, to our knowledge prevalence of ACEs among persons with a h...

journal_title：JAMA psychiatry

authors： Blosnich JR,Dichter ME,Cerulli C,Batten SV,Bossarte RM

更新日期：2014-09-01 00:00:00

abstract：Importance:Because more than one-third of people making nonfatal suicide attempts do not receive mental health treatment, it is essential to extend suicide attempt risk factors beyond high-risk clinical populations to the general adult population. Objective:To identify future suicide attempt risk factors in the genera...

journal_title：JAMA psychiatry

authors： García de la Garza Á,Blanco C,Olfson M,Wall MM

更新日期：2021-01-06 00:00:00

abstract：:CONTEXT Clinical experience and factor analytic studies suggest that some psychiatric disorders may be more closely related to one another, as indicated by the frequency of their co-occurrence, which may have etiologic and treatment implications. OBJECTIVE To construct a virtual space of common psychiatric disorders, ...

journal_title：JAMA psychiatry

authors： Blanco C,Krueger RF,Hasin DS,Liu SM,Wang S,Kerridge BT,Saha T,Olfson M

更新日期：2013-02-01 00:00:00

abstract：IMPORTANCE:Compulsory admissions, defined as admissions against the will of the patient (according to local judicial procedures), have a strong effect on psychiatric patients. In several Western countries, the rate of such admissions is tending to rise. Its reduction is urgently needed. OBJECTIVE:To establish which in...

journal_title：JAMA psychiatry

authors： de Jong MH,Kamperman AM,Oorschot M,Priebe S,Bramer W,van de Sande R,Van Gool AR,Mulder CL

更新日期：2016-07-01 00:00:00

abstract：Importance:Depressive severity is typically measured according to total scores on questionnaires that include a diverse range of symptoms despite convincing evidence that depression is not a unitary construct. When evaluated according to aggregate measurements, treatment efficacy is generally modest and differences in ...

journal_title：JAMA psychiatry

authors： Chekroud AM,Gueorguieva R,Krumholz HM,Trivedi MH,Krystal JH,McCarthy G

更新日期：2017-04-01 00:00:00

abstract：IMPORTANCE:In schizophrenia, working memory deficits appear to reflect abnormalities in the generation of gamma oscillations in the dorsolateral prefrontal cortex. The generation of gamma oscillations requires the phasic excitation of inhibitory parvalbumin-containing interneurons. Thus, gamma oscillations depend, in p...

journal_title：JAMA psychiatry

authors： Kimoto S,Zaki MM,Bazmi HH,Lewis DA

更新日期：2015-08-01 00:00:00

abstract：Importance:Understanding the neurodevelopmental trajectory of psychiatric symptoms is important for improving early identification, intervention, and prevention of mental disorders. Objective:To test whether the strength of the coupling of activation between specific brain regions, as measured by resting-state functio...

journal_title：JAMA psychiatry

authors： Whitfield-Gabrieli S,Wendelken C,Nieto-Castañón A,Bailey SK,Anteraper SA,Lee YJ,Chai XQ,Hirshfeld-Becker DR,Biederman J,Cutting LE,Bunge SA

更新日期：2020-04-01 00:00:00

abstract：IMPORTANCE:The single-nucleotide polymorphism rs1344706 in the zinc finger protein 804A gene (ZNF804A) shows genome-wide association with schizophrenia and bipolar disorder. Little is known regarding the expression of ZNF804A and the functionality of rs1344706. OBJECTIVES:To characterize ZNF804A expression in human br...

journal_title：JAMA psychiatry

authors： Tao R,Cousijn H,Jaffe AE,Burnet PW,Edwards F,Eastwood SL,Shin JH,Lane TA,Walker MA,Maher BJ,Weinberger DR,Harrison PJ,Hyde TM,Kleinman JE

更新日期：2014-10-01 00:00:00

abstract：Importance:More than 30 million people live with a stroke diagnosis worldwide. Depression after stroke is frequent, and greater knowledge of associated risk factors and outcomes is needed to understand the etiology and implications of this disabling complication. Objectives:To examine whether the incidence of and risk...

journal_title：JAMA psychiatry

authors： Jørgensen TS,Wium-Andersen IK,Wium-Andersen MK,Jørgensen MB,Prescott E,Maartensson S,Kragh-Andersen P,Osler M

更新日期：2016-10-01 00:00:00

abstract：Importance:Generalized anxiety disorder (GAD) is poorly understood compared with other anxiety disorders, and debates persist about the seriousness of this disorder. Few data exist on GAD outside a small number of affluent, industrialized nations. No population-based data exist on GAD as it is currently defined in DSM-...

journal_title：JAMA psychiatry

authors： Ruscio AM,Hallion LS,Lim CCW,Aguilar-Gaxiola S,Al-Hamzawi A,Alonso J,Andrade LH,Borges G,Bromet EJ,Bunting B,Caldas de Almeida JM,Demyttenaere K,Florescu S,de Girolamo G,Gureje O,Haro JM,He Y,Hinkov H,Hu C,de Jonge

更新日期：2017-05-01 00:00:00

abstract：Importance:Several psychotherapy protocols have been evaluated as adjuncts to pharmacotherapy for patients with bipolar disorder, but little is known about their comparative effectiveness. Objective:To use systematic review and network meta-analysis to compare the association of using manualized psychotherapies and th...

journal_title：JAMA psychiatry

authors： Miklowitz DJ,Efthimiou O,Furukawa TA,Scott J,McLaren R,Geddes JR,Cipriani A

更新日期：2020-10-14 00:00:00

abstract：IMPORTANCE:Although depression and type 2 diabetes mellitus (DM) may independently increase the risk for dementia, no studies have examined whether the risk for dementia among people with comorbid depression and DM is higher than the sum of each exposure individually. OBJECTIVE:To examine the risk for all-cause dement...

journal_title：JAMA psychiatry

authors： Katon W,Pedersen HS,Ribe AR,Fenger-Grøn M,Davydow D,Waldorff FB,Vestergaard M

更新日期：2015-06-01 00:00:00

abstract：IMPORTANCE:National epidemiologic information from recently collected data on the new DSM-5 classification of alcohol use disorder (AUD) using a reliable, valid, and uniform data source is needed. OBJECTIVE:To present nationally representative findings on the prevalence, correlates, psychiatric comorbidity, associated...

journal_title：JAMA psychiatry

authors： Grant BF,Goldstein RB,Saha TD,Chou SP,Jung J,Zhang H,Pickering RP,Ruan WJ,Smith SM,Huang B,Hasin DS

更新日期：2015-08-01 00:00:00

abstract：IMPORTANCE:At least 11 rare copy number variants (CNVs) have been shown to be major risk factors for schizophrenia (SZ). These CNVs also increase the risk for other neurodevelopmental disorders, such as intellectual disability. It is possible that additional intellectual disability-associated CNVs increase the risk for...

journal_title：JAMA psychiatry

authors： Rees E,Kendall K,Pardiñas AF,Legge SE,Pocklington A,Escott-Price V,MacCabe JH,Collier DA,Holmans P,O'Donovan MC,Owen MJ,Walters JTR,Kirov G

更新日期：2016-09-01 00:00:00

abstract：Importance:Growing evidence suggests that prescription opioid use affects depression and anxiety disorders; however, observational studies are subject to confounding, making causal inference and determining the direction of these associations difficult. Objective:To investigate the potential bidirectional associations...

journal_title：JAMA psychiatry

authors： Rosoff DB,Smith GD,Lohoff FW

更新日期：2020-11-11 00:00:00