Abstract:
OBJECTIVES:To quantitatively evaluate and compare nerve density in patients with limited cutaneous systemic sclerosis (lcSSc) and control subjects using high-resolution ultrasound (US) with a computer-aided assessment. METHODS:Forty patients and 40 age- and sex-matched control subjects were prospectively enrolled. Ultrasound (US) examination (17-5 MHz probe) of the median nerve at the elbow was performed bilaterally by one radiologist. A software quantified the ratio between the hypoechoic and hyperechoic areas of peripheral nerves on ultrasound. Two observers set the threshold in the images acquired, and three observers performed the digital analysis of nerve density. Statistical analysis included Mann-Whitney U-test of patients versus control subjects and subgroup analysis of symptomatic and non-symptomatic patients. Intra and inter-observer agreement of the three observers were assessed with the kappa statistic. RESULTS:In all, 160 median nerves were evaluated. According to the US, nerve density was significantly reduced in lcSSc patients compared to control subjects (mean and standard deviation: 41 ± 3 vs 56 ± 4, p < 0.01). Subgroup analysis showed that symptomatic patients (n = 15) had reduced nerve density compared to non-symptomatic (n = 25) patients (39 ± 5 vs 43 ± 4, p < 0.01). Intra-observer agreement was very good (K = 0.82). Inter-observer agreements were good: reader 1 vs reader 2: k = 0.78 (95% confidence interval 0.65 to 0.91); reader 2 vs reader 3: k = 0.72 (95% confidence interval 0.65 to 0.82); reader 3 vs reader 1: k = 0.71 (95% confidence interval 0.64-0.81). CONCLUSIONS:In lcSSc patients, nerve density was reduced, especially in the symptomatic group, compared to control subjects.
journal_name
Skeletal Radioljournal_title
Skeletal radiologyauthors
Bignotti B,Ghio M,Panico N,Tagliafico G,Martinoli C,Tagliafico Adoi
10.1007/s00256-015-2230-5subject
Has Abstractpub_date
2015-12-01 00:00:00pages
1761-7issue
12eissn
0364-2348issn
1432-2161pii
10.1007/s00256-015-2230-5journal_volume
44pub_type
杂志文章abstract::Fourteen telangiectatic osteosarcomas are reported. They are rare, clinically and radiologically aggressive lesions, involving mainly the femurs of young patients, often misdiagnosed as aneurysmal bone cysts. An explanation for a characteristic early radiological appearance consisting of regular parallel striations of...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00356952
更新日期:1987-01-01 00:00:00
abstract::A young girl had a large isolated and localized multicystic lesion of the right humerus, which was revealed by a pathological fracture. MRI and bone biopsy showed liquid-filled bone cysts. The final diagnosis was localized cystic lymphangiomatosis. ...
journal_title:Skeletal radiology
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abstract:OBJECTIVE:We demonstrate the clinical use of an MR angiography sequence performed with sparse k-space sampling (MRA), as a method for dynamic contrast-enhanced (DCE)-MRI, and apply it to the assessment of sarcomas for treatment response. MATERIALS AND METHODS:Three subjects with sarcomas (2 with osteosarcoma, 1 with h...
journal_title:Skeletal radiology
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doi:10.1007/s00256-013-1604-9
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abstract::Femoroacetabular impingement syndrome (FAI) is a pathologic entity which can lead to chronic symptoms of pain, reduced range of motion in flexion and internal rotation, and has been shown to correlate with degenerative arthritis of the hip. History, physical examination, and supportive radiographic findings such as ev...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-005-0932-9
更新日期:2005-11-01 00:00:00
abstract:OBJECTIVE:To develop and validate a deep convolutional neural network (CNN) method capable of (1) selecting a specific shoulder sagittal MR image (Y-view) and (2) automatically segmenting rotator cuff (RC) muscles on a Y-view. We hypothesized a CNN approach can accurately perform both tasks compared with manual referen...
journal_title:Skeletal radiology
pub_type: 杂志文章
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更新日期:2020-09-16 00:00:00
abstract:OBJECTIVES:This study evaluates whether the recently described lateral mortise (LM) approach to therapeutic ankle injections can also be used to inject the ankle prior to magnetic resonance arthrography (MRA) without impairing the evaluation of the anterior talofibular ligament (ATFL). MATERIALS AND METHODS:An IRB-app...
journal_title:Skeletal radiology
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doi:10.1007/s00256-013-1740-2
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to investigate skeletal muscle denervation using diffusion-weighted magnetic resonance imaging (DWMRI). MATERIALS AND METHODS:Sciatic nerve axotomy was performed in a group of nine New Zealand White rabbits, and electromyographic (EMG), pathological, and DWMRI studies were conducted...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-008-0552-2
更新日期:2008-12-01 00:00:00
abstract::A rare case of tuberculosis of the patella is presented. Diagnostic features include an osteolytic lesion in the patella with flaky sequestrum, associated with typical clinical features. Treatment should be urgent and should include a regimen of surgical debridement along with four antitubercular drugs. Once the joint...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s002560050334
更新日期:1998-01-01 00:00:00
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journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF02341664
更新日期:1991-01-01 00:00:00
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journal_title:Skeletal radiology
pub_type: 杂志文章
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journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-010-1021-2
更新日期:2011-07-01 00:00:00
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journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-014-1992-5
更新日期:2015-01-01 00:00:00
abstract:PURPOSE:To determine (i) whether intra-articular gadolinium from MR arthrography (MRA) results in gadolinium deposition in the brain and (ii) whether there is a correlation between intra-articular gadolinium dose and intracranial gadolinium deposition. MATERIALS AND METHODS:This retrospective study was institutional r...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-020-03380-5
更新日期:2020-07-01 00:00:00
abstract::Plain radiographs of the limbs were reviewed after replantation procedures following traumatic amputation in 5 patients at the wrist (2), mid-forearm (2) and knee (1). Following upper limb replantation, rapid development of osteopaenia was initially noted in the juxta-articular regions and metaphyses of the tubular bo...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00242128
更新日期:1992-01-01 00:00:00
abstract::We report on three boys suffering from achondroplasia concurrent with enchondromatosis-like metaphyseal changes. Two boys who were examined by molecular analysis harbored a mutation of FGFR3, which occurs in most achondroplastic individuals. Given the prevalence of achondroplasia and enchondromatosis, the metaphyseal ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-006-0161-x
更新日期:2007-06-01 00:00:00
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journal_title:Skeletal radiology
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doi:10.1007/s00256-018-2892-x
更新日期:2018-08-01 00:00:00
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journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-011-1260-x
更新日期:2011-12-01 00:00:00
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journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-011-1339-4
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abstract::A case of OCC in a 35-year-old woman is presented. Proof was obtained by open biopsy. This rare entity is benign and its etiology is still obscure. No definite association with osteitis pubis or osteitis condensans ilii has been reported. The involvement of the clavicle is invariably unilateral. The clinical and radio...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00193100
更新日期:1990-01-01 00:00:00
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journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-008-0612-7
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journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00361132
更新日期:1984-01-01 00:00:00
abstract::The radiomorphological appearance of fibrous metaphyseal defects (FMDs) is demonstrated by long-term follow-up studies. A characteristic radiomorphological course rather than a typical single appearance can be established. These findings correlate well with the duration of these tumor-like lesions; therefore, the radi...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00361448
更新日期:1988-01-01 00:00:00
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journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-017-2868-2
更新日期:2018-06-01 00:00:00
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journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-005-0026-8
更新日期:2006-03-01 00:00:00
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journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-004-0848-9
更新日期:2005-01-01 00:00:00
abstract:UNLABELLED:To evaluate the computed tomography (CT) findings of inflammatory lesions of the sternoclavicular joints (SCJ) in spondylarthropathies. DESIGN AND PATIENTS:CT scans of the SCJs were obtained in 23 patients (group 1) with inflammatory SCJ lesions in spondylarthropathies. These scans were reviewed by four rea...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s002560050258
更新日期:1997-07-01 00:00:00
abstract::Magnetic resonance imaging has had a dramatic effect on the means by which we diagnose ligament injuries. Tears resulting from either acute trauma or overuse can be detected noninvasively, directing appropriate therapy be it conservative or surgical. For the elite athlete, earlier diagnosis leads to earlier interventi...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s002560050476
更新日期:1999-02-01 00:00:00
abstract::Skeletal lesions were radiographically apparent in 6 of 36 (16%) patients with chronic myelogenous leukemia. The spectrum of radiographic changes including diffuse osteoporosis, focal osteolytic and osteoblastic lesions, chloroma, and arthritis, and their clinical behavior is discussed. ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00347255
更新日期:1980-01-01 00:00:00
abstract:OBJECTIVE:To document the imaging findings observed in patients with an unusual pattern of abnormality of the femoral head, most likely representing osteonecrosis. DESIGN AND PATIENTS:The imaging findings in 11 patients (10 men, 1 woman; age range 32-55 years) with a distinct lesion of the femoral head were reviewed w...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-002-0503-2
更新日期:2002-08-01 00:00:00
abstract::Fatigue stress fractures are quite common in athletes, especially in women. They typically involve the lower extremities, but they have also been described in the pelvis and sacrum. Most of the time, they are radiographically occult at the beginning, and become visible only when the callus is detected. They are suspec...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-011-1244-x
更新日期:2012-01-01 00:00:00