Magnetic resonance imaging of intramuscular myxoma with histological comparison and a review of the literature.

Abstract:

OBJECTIVE:To evaluate the magnetic resonance (MR) features of intramuscular myxoma (IM) compared with its pathological findings. DESIGN:Two radiologists retrospectively reviewed records and imaging studies of patients with histologically proven IM. Two radiologists also analyzed by consensus all the MR studies (pre- and post-contrast T1-weighted and T2-weighted sequences) and a pathologist reviewed the available histological material. PATIENTS:Seventeen patients with 18 histologically proven IM were reviewed. Histological samples of 11 of these 18 tumors were available for pathological analysis. RESULTS:There were 14 women and three men, with a mean age of 58.9 years. IM involved predominantly the thigh (n=10). MR imaging showed well-circumscribed intramuscular masses, hypointense on T1-weighted and hyperintense on T2-weighted images. Eleven masses were homogeneous and seven slightly heterogeneous due to fibrous septa. Enhanced MR imaging demonstrated three different patterns: peripheral enhancement (n=1), peripheral and patchy internal enhancement (n=7) or peripheral and linear internal enhancement (n=4). Intratumoral cysts were detected in four masses. MR imaging showed the presence of a pseudocapsule (n=12), fat around the lesion (n=16) and peritumoral edema (n=16). Histologically, all the tumors were hypocellular, hypovascular and myxoid. Peripheral areas of collagenous fibers formed a partial capsule and IM often merged into surrounding muscular fibers. More cellular tumors and those with scanty myxoid stroma tended to show a more prominent internal enhancement. CONCLUSION:IM shows several recognizable MR features which suggest its diagnosis.

journal_name

Skeletal Radiol

journal_title

Skeletal radiology

authors

Luna A,Martinez S,Bossen E

doi

10.1007/s00256-004-0848-9

keywords:

subject

Has Abstract

pub_date

2005-01-01 00:00:00

pages

19-28

issue

1

eissn

0364-2348

issn

1432-2161

journal_volume

34

pub_type

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