Abstract：
OBJECTIVE:The purpose of this study was to evaluate differences in parameters of diffusion kurtosis imaging (DKI) and minimum apparent diffusion coefficient (ADCmin) between benign and malignant musculoskeletal tumors. MATERIALS AND METHODS:In this prospective study, 43 patients were scanned using a DKI protocol on a 3-T MR scanner. Eligibility criteria were: non-fatty, non-cystic soft tissue or osteolytic tumors; > 2 cm; location in the retroperitoneum, pelvis, leg, or neck; and no prior treatment. They were clinically or histologically diagnosed as benign (n = 27) or malignant (n = 16). In the DKI protocol, diffusion-weighted imaging was performed using four b values (0-2000 s/mm2) and 21 diffusion directions. Mean kurtosis (MK) values were calculated on the MR console. A recently developed software application enabling reliable calculation was used for DKI analysis. RESULTS:MK showed a strong correction with ADCmin (Spearman's rs = 0.95). Both MK and ADCmin values differed between benign and malignant tumors (p < 0.01). For benign and malignant tumors, the mean MK values (± SD) were 0.49 ± 0.17 and 1.14 ± 0.30, respectively, and ADCmin values were 1.54 ± 0.47 and 0.49 ± 0.17 × 10-3 mm2/s, respectively. At cutoffs of MK = 0.81 and ADCmin = 0.77 × 10-3 mm2/s, the specificity and sensitivity for diagnosis of malignant tumors were 96.3 and 93.8% for MK and 96.3 and 93.8% for ADCmin, respectively. The areas under the curve were 0.97 and 0.99 for MK and ADCmin, respectively (p = 0.31). CONCLUSIONS:MK and ADCmin showed high diagnostic accuracy and strong correlation, reflecting the accuracy of MK. However, no clear added value of DKI could be demonstrated in differentiating musculoskeletal tumors.
journal_name
Skeletal Radioljournal_title
Skeletal radiologyauthors
Ogawa M,Kan H,Arai N,Murai T,Manabe Y,Sawada Y,Shibamoto Ydoi
10.1007/s00256-018-2946-0subject
Has Abstractpub_date
2019-02-01 00:00:00pages
285-292issue
2eissn
0364-2348issn
1432-2161pii
10.1007/s00256-018-2946-0journal_volume
48pub_type
杂志文章abstract：:A case of polymyositis and localized vasculitis presenting as a muscular pseudotumor of a lower extremity and periostitis several years after the onset of symptoms was reported and the MRI characteristics were described. This imaging modality demonstrated muscle signal abnormalities in several muscle groups and was us...
journal_title：Skeletal radiology
pub_type： 杂志文章,评审
doi：10.1007/BF00223096
更新日期：1994-10-01 00:00:00
abstract：:The relationship of the posterior aspects of the atlas and the axis were studied in 100 normal adult volunteers. The ratio of the height of the atlantal spinolaminar line to the atlantoaxial interspinous distance was found to be remarkably constant and was less than 2.0 in all men and women. This ratio should prove he...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/BF00193824
更新日期：1991-01-01 00:00:00
abstract：OBJECTIVE:The purpose of this study is to investigate if relying on postal questionnaires returned by patients provides an accurate representation of reported outcomes from patients receiving imaging-guided lumbar nerve root injections (NRIs). MATERIALS AND METHODS:Patients who received imaging-guided transforaminal l...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-013-1673-9
更新日期：2013-10-01 00:00:00
abstract：:We report an extremely rare case of partial scapular duplication. Mild shoulder area deformity in a newborn prompted further evaluation that included radiography, ultrasonography and spiral CT. These revealed an additional bone in the area of the left shoulder, above the humerus and lateral to the scapula. The accesso...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-005-0936-5
更新日期：2006-09-01 00:00:00
abstract：OBJECTIVE:To evaluate MRI as a problem-solving tool for patients with an unexplained failed total hip replacement following conventional radiological assessment. METHODS AND MATERIALS:Patients' informed consent was obtained in all cases. Institutional review board approval was obtained. Twenty-eight patients with unex...
journal_title：Skeletal radiology
pub_type： 临床试验,杂志文章
doi：10.1007/s00256-007-0349-8
更新日期：2007-10-01 00:00:00
abstract：:A tear at the origin of the deltoid muscle is uncommon and usually occurs as a complication of shoulder surgery. We report a case of spontaneous deltoid detachment as a complication of massive rotator cuff tear in a 70-year-old woman evaluated by standard radiographs, ultrasound, arthrography and MR-arthrography. We p...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-005-0046-4
更新日期：2006-06-01 00:00:00
abstract：:Langerhans cell histiocytosis (LCH) is an uncommon disorder of unknown etiology with a wide spectrum of biological behavior. The most common sites of involvement are bone, skin, and lung. While osseous LCH can result in secondary soft tissue involvement, primary soft tissue LCH in extremities with secondary bone invol...
journal_title：Skeletal radiology
pub_type： 杂志文章,评审
doi：10.1007/s00256-013-1611-x
更新日期：2013-09-01 00:00:00
abstract：:We report two sisters who have a rare skeletal abnormality termed Patterson-Lowry rhizomelic dysplasia. The typical findings of these cases on bone survey are isolated shortening and proximal metaphyseal enlargement and cupping of the bilateral humeri. The elder sister also has coxa vara deformity and dysplastic proxi...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-014-1957-8
更新日期：2014-11-01 00:00:00
abstract：OBJECTIVE:Zoledronic acid (ZOL) has a suppressive effect on marrow adiposity in ovariectomized rats. Currently, however, data on the effect of ZOL on marrow fat in humans are unavailable. The purpose of this work was to determine the in vivo effect of ZOL on bone remodeling and marrow adipogenesis in postmenopausal ost...
journal_title：Skeletal radiology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00256-015-2200-y
更新日期：2015-10-01 00:00:00
abstract：:Melanotic neuroectodermal tumor of infancy (MNTI) is an uncommon tumor of neural crest origin, almost invariably identified in the head and neck region. It is a relatively benign tumor but can recur and rarely metastasize. Herein, a rare case of MNTI in the thigh of an infant is documented. Radiographic imaging showed...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-011-1113-7
更新日期：2011-08-01 00:00:00
abstract：:Magnetic resonance imaging (MRI) has proven to be an ideal technique for evaluating tendons and ligaments, which, because of their fibrous structure, have a low signal intensity on all sequences. Trauma and a wide variety of other conditions cause aberrations in the normal appearance of these structures, ranging from ...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/BF00243084
更新日期：1992-01-01 00:00:00
abstract：OBJECTIVE:To compare CR with CT (static and dynamic) to evaluate upper spine instability and to determine if CT in flexion adds value compared to MR imaging in neutral position to assess compression of the subarachnoid space and of the spinal cord. MATERIALS AND METHODS:Twenty-one consecutive patients with atlantoaxia...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-014-2000-9
更新日期：2015-02-01 00:00:00
abstract：:Pain affecting the foot and ankle is a common complaint frequently attributable to inflammatory joint diseases. Although conventional radiography is regarded as the initial step in the diagnostic investigation, MR imaging may contribute to further evaluation of these patients due to the direct visualization of the inf...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s002560050571
更新日期：1999-12-01 00:00:00
abstract：OBJECTIVES:Total elbow arthroplasty (TEA) is becoming a popular alternative to arthrodesis for patients with end-stage elbow arthrosis and comminuted distal humeral fractures. Prior outcome studies have primarily focused on surgical findings. Our purpose is to determine the radiographic outcome of TEA and to correlate ...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-016-2351-5
更新日期：2016-06-01 00:00:00
abstract：OBJECTIVE:To evaluate the evolution of the ultrasonographic pubo-femoral distance (PFD) before and after Pavlik harness treatment for developmental dysplasia of the hip (DDH) in newborns. PATIENTS AND METHODS:Twenty-five patients (16.7 ± 10.4 days; 19 females, six males) diagnosed with DDH and treated using the Pavlik...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-017-2668-8
更新日期：2017-09-01 00:00:00
abstract：OBJECTIVE:To evaluate the sonographic findings of the rotator interval in patients with clinical evidence of adhesive capsulitis immediately prior to arthroscopy. DESIGN AND PATIENTS:We prospectively compared 30 patients with clinically diagnosed adhesive capsulitis (20 females, 10 males, mean age 50 years) with a con...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-005-0957-0
更新日期：2005-09-01 00:00:00
abstract：OBJECTIVE:The purpose of the study was to determine if the thickness of the subacromial-subdeltoid (SASD) bursa during dynamic ultrasound and on static views differs between patients with shoulder impingement syndrome and healthy volunteers. MATERIALS AND METHODS:Twenty-two patients with a clinical diagnosis of should...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-011-1295-z
更新日期：2012-09-01 00:00:00
abstract：OBJECTIVE:MRI signal intensity of pediatric bone marrow can be difficult to interpret using conventional methods. Chemical shift imaging (CSI), which can quantitatively assess relative fat content, may improve the ability to accurately diagnose bone marrow abnormalities in children. METHODS:Consecutive pelvis and extr...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-016-2403-x
更新日期：2016-09-01 00:00:00
abstract：PURPOSE:The goal of our study was to determine the frequency of intra-articular calcifications on initial postoperative radiographs following arthroscopic ACL reconstruction, describe their appearance, hypothesize their etiology, and determine their significance. MATERIALS AND METHODS:Review of records and post-operat...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-013-1773-6
更新日期：2014-02-01 00:00:00
abstract：OBJECTIVE:To determine the accuracy of MRI in the assessment of the radiographically occult scaphoid fracture. DESIGN:This prospective study compared the sensitivity and specificity of MRI for detection of radiographically occult scaphoid fractures with bone scintigraphy (BS), the currently accepted imaging modality o...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s002560050459
更新日期：1998-12-01 00:00:00
abstract：:We believe MR findings to be quite characteristic of primary lymphedema. We believe that MR has a role in diagnosing lymphedema and its complications. ...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/BF00204617
更新日期：1994-08-01 00:00:00
abstract：OBJECTIVE:To describe the MR features of mucoid degeneration of the anterior cruciate ligament (ACL) in a series of patients with MRI findings that were mistaken for tears in the majority of cases but who were found to have an intact ligament at arthroscopy. We will suggest a pathologic entity corresponding to this fin...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s002560100336
更新日期：2001-06-01 00:00:00
abstract：:A small spur seen at the edge of an open epiphyseal line indicates the presence of an open epiphysis when this is not clear radiographically. In addition, the spur should not be mistaken for an avulsion fracture. ...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/BF00347260
更新日期：1980-01-01 00:00:00
abstract：:Femoroacetabular impingement syndrome (FAI) is a pathologic entity which can lead to chronic symptoms of pain, reduced range of motion in flexion and internal rotation, and has been shown to correlate with degenerative arthritis of the hip. History, physical examination, and supportive radiographic findings such as ev...
journal_title：Skeletal radiology
pub_type： 杂志文章,评审
doi：10.1007/s00256-005-0932-9
更新日期：2005-11-01 00:00:00
abstract：:The Magnetic Resonance Imaging (MRI) appearances of primary osseous hemangiopericytoma (HPC) have been rarely described. We report on a 46-year-old Chinese man with primary osseous HPC of the right tibia. The characteristic vascular distribution of this tumor, presenting with a "spoke-wheel" appearance on MR images an...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s002560050009
更新日期：2000-01-01 00:00:00
abstract：:Semimembranosus tendon avulsion fractures are an uncommon occurrence and are often associated with anterior cruciate ligament (ACL) and medial meniscus tears. We present the imaging features of an unusual case of semimembranosus avulsion fracture of the posteromedial tibial plateau associated with posterior cruciate l...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-013-1719-z
更新日期：2014-02-01 00:00:00
abstract：OBJECTIVE:In diagnosing osteomyelitis (OM) both MRI and [18 F]FDG PET-CT proved to be accurate modalities. In anticipation of the advent of hybrid PET/MRI scanners we analyzed our patient group to give direction to future imaging strategies in patients with suspected OM. MATERIALS AND METHODS:In this retrospective stu...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-014-1844-3
更新日期：2014-05-01 00:00:00
abstract：:Lipoma arborescens is a rare benign intra-articular lesion of unknown etiology that usually involves the suprapatellar pouch of the knee joint. Clinically, the most common finding is a slow-growing painless swelling, accompanied by intermittent effusion of the joint. We report a case of a multifocal lipoma arborescens...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-005-0900-4
更新日期：2005-09-01 00:00:00
abstract：:During recent years the combination of surgery, radiotherapy, and multiple chemotherapy in the treatment of patients with cancer has resulted in increased survival periods and, in some cases, complete cures. In children, however, the subsequent development of other and apparently unrelated malignancies has been observ...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/BF00348796
更新日期：1984-01-01 00:00:00
abstract：:Prostaglandin E therapy in infants causes periosteal elevation. Although the changes usually take 30-40 days to become visible, we have seen them as early as nine days. In 15 infants who had prostaglandin E therapy for over six days, three developed periosteal elevation. Three other cases are described in greater deta...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/BF00361189
更新日期：1985-01-01 00:00:00
