Abstract:
OBJECTIVE:In order to clarify the increased 2-deoxy-2-fluoro-(18)F-D: -glucopyranose ((18)F-FDG) accumulation in schwannoma by positron emission tomography (PET) analysis, immunohistochemical analysis for the factors involved in glucose transportation and vascular formation was performed. MATERIALS AND METHODS:Twenty-six patients with schwannoma (13 men and 13 women) with ages ranging from 27 to 75 years, who received whole body (18)F-FDG PET scan, were enrolled for the present study. The retention index (RI) was calculated by dividing the increase in the standardized uptake value (SUVmax) at the delayed scan by the SUVmax in the early scan. SUVmax and RI were compared with the histologic variables, including the expression of glucose transporters 1 and 3, hexokinase II, vascular endothelial growth factor/vascular permeability factor (VEGF/VPF), and microvascular density shown by CD31 immunohistochemistry. RESULTS:Mean SUVmax values in the early and delayed scans were 2.64 +/- 1.47 and 2.71 +/- 1.57 (mean +/- SD), respectively. RI was -2.5 +/- 21 (percentage). SUVmax showed a positive correlation with the tumor size (tumor size <5 cm, 2.06 +/- 0.72; >5 cm, 3.95 +/- 1.89; p < 0.05) and the microvascular density (negative density, 2.16 +/- 1.12; positive density, 3.56 +/- 1.67; p < 0.05). RI correlated with VEGF/VPF expression in the tumors (negative expression, -11 +/- 6.1; positive expression, 13 +/- 8.1; p < 0.05). Other factors showed no correlation with SUVmax or RI. CONCLUSIONS:Microvascular density and vascular permeability of the tumor are suggested to affect the enhanced (18)F-FDG accumulation in schwannoma.
journal_name
Skeletal Radioljournal_title
Skeletal radiologyauthors
Hamada K,Tomita Y,Qiu Y,Tomoeda M,Ueda T,Tamai N,Hashimoto N,Yoshikawa H,Aozasa K,Hatazawa Jdoi
10.1007/s00256-008-0612-7subject
Has Abstractpub_date
2009-03-01 00:00:00pages
261-6issue
3eissn
0364-2348issn
1432-2161journal_volume
38pub_type
杂志文章abstract:OBJECTIVE:To evaluate the magnetic resonance (MR) features of intramuscular myxoma (IM) compared with its pathological findings. DESIGN:Two radiologists retrospectively reviewed records and imaging studies of patients with histologically proven IM. Two radiologists also analyzed by consensus all the MR studies (pre- a...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-004-0848-9
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to describe a variety of non-neoplastic causes of high-signal-intensity areas seen on T2-weighted magnetic resonance (MR) images obtained after treatment for malignant musculoskeletal neoplasm. DESIGN:MR examinations obtained after treatment for malignant musculoskeletal neopl...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00228920
更新日期:1995-04-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the correlations between T2 value, T2* value, and histological grades of degenerated human articular cartilage. MATERIALS AND METHODS:T2 mapping and T2* mapping of nine tibial osteochondral specimens were obtained using a 3-T MRI after total knee arthroplasty. A total of...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-014-1872-z
更新日期:2014-07-01 00:00:00
abstract:OBJECTIVE:To determine the optimal intra-articular iodine concentration for C-arm flat-panel computed tomography (FPCT) arthrography using advanced joint phantoms and to evaluate its application in human cadaveric wrists and elbows. Multi-detector (MD) CT served as the standard of reference. MATERIALS AND METHODS:Join...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-012-1501-7
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVE:To describe the MR appearance following autogenous osteochondral "plug" transfer for the treatment of focal chondral defects of the knee. DESIGN AND PATIENTS:Twenty-nine 1.5-T MR knee studies including dynamic gadolinium enhancement were performed on 21 patients following autogenous osteochondral "plug" tran...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s002560100371
更新日期:2001-10-01 00:00:00
abstract::For the objective assessment of the severity and progression of osteoporotic deformities of the spine, a mathematical model has been developed which permits evaluation of a single set of radiographs of the spine without reference to absolute values of vertebral height. The model was based on measurements of anterior, ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00197612
更新日期:1990-01-01 00:00:00
abstract::The objective of this study was the validation of a CT multiprojection scout view method for the evaluation of cervical spine integrity in severely head-injured patients. Following brain CT, 130 consecutive patients underwent anteroposterior, laterolateral, and 45 degrees right and left oblique scout views of the cerv...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s002560050073
更新日期:1996-04-01 00:00:00
abstract::Computed tomography was used to identify three different ways in which primary bone tumors may transgress a bony cortex. Analysis of the pattern of cortical transgression was used in conjunction with the presence or absence of matrix mineralization to classify correctly the lesion into one of four different diagnostic...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00355103
更新日期:1986-01-01 00:00:00
abstract:OBJECTIVE:A bone infarct may occasionally dedifferentiate to osteogenic sarcoma, fibrosarcoma or malignant fibrous histiocytoma. However, the association of an angiosarcoma with a bone infarct is extremely rare. Such an association is presented in three patients. Their clinical course is compared with that of patients ...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s002560050435
更新日期:1998-10-01 00:00:00
abstract::Muscle herniation can be defined as protrusion of a portion of muscle through an acquired or congenital defect of enclosing fascia. Although it is usually a cosmetic problem, it can lead to local pain and tenderness after prolonged exertion. In this report, we present a case of flexor digitorum superficialis muscle he...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-002-0615-8
更新日期:2003-06-01 00:00:00
abstract::We report on a 9-year-old boy with metachronous aneurysmal bone cysts involving the tibia and pubis respectively. The patient has been clinically and radiographically followed for 3 years. ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s002560050288
更新日期:1997-09-01 00:00:00
abstract:OBJECTIVE:We used magnetic resonance imaging (MRI) to evaluate where articular degeneration begins and which ligaments are most often involved in the early clinical stage first carpometacarpal joint (CMCJ-1) osteoarthritis. MATERIALS AND METHODS:We retrospectively analyzed the MRI findings of 26 patients with early cl...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-020-03383-2
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to evaluate whether ultrasound allows precise assessment of a focal defect at the lateral patellar retinaculum (LPR) and to determine its anatomical significance. MATERIALS AND METHODS:This work was initially undertaken in four cadaveric specimens and followed by high-resolution...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-019-03209-w
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVE:The aim of this paper is to demonstrate the usefulness of 2D multiplanar reformatting images (MPR) obtained from rotational acquisitions with cone-beam computed tomography technology during percutaneous extra-vascular spinal procedures performed in the angiography suite. METHODS:We used a 3D rotational angio...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-011-1282-4
更新日期:2011-12-01 00:00:00
abstract:OBJECTIVE:Although the normal adult human intervertebral disc is considered to be avascular, vascularised cellular fibrous tissue can be found in pathological conditions involving the disc such as disc herniation. Whether lymphatics vessels form a component of this reparative tissue is not known as the presence or abse...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-009-0770-2
更新日期:2009-12-01 00:00:00
abstract::Posterior spinal tuberculosis or arch tuberculosis is a form of skeletal tuberculosis that selectively involves the vertebral arch. It may mimic skeletal neoplasm clinically and radiographically. Although posterior spinal tuberculosis has been reported in developing countries it has rarely been found in the United Sta...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s002560050322
更新日期:1997-12-01 00:00:00
abstract::We present a case of a hibernoma arising from the left axilla in a 24-year-old woman. The imaging characteristics on both contrast-enhanced CT (attenuation similar to surrounding skeletal muscle) and T1-weighted MR imaging (signal intensity intermediate between those of skeletal muscle and subcutaneous fat) were incon...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-002-0533-9
更新日期:2003-05-01 00:00:00
abstract::The appearance on magnetic resonance imaging (MRI) of 16 cases of pathologically proven eosinophilic granuloma were reviewed retrospectively and correlated with the radiographic appearance of the lesion. The most common MR appearance (ten cases) was a focal lesion, surrounded by an extensive, ill-defined bone marrow a...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00206144
更新日期:1993-01-01 00:00:00
abstract:OBJECTIVE:To describe the imaging features of plexiform fibrohistiocytic tumor and its associated clinical findings. MATERIALS AND METHODS:An institutional database was searched to identify all patients with a pathological diagnosis of plexiform fibrohistiocytic tumor. The electronic medical record was reviewed for re...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-018-3050-1
更新日期:2019-03-01 00:00:00
abstract::Radial wrist pain is a common clinical complaint. The relatively complex anatomy in this region, combined with the small size of the anatomical structures and occasionally subtle imaging findings, can pose problems when trying to localize the exact cause of pain. To fully comprehend the underlying pathology, one needs...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-014-1840-7
更新日期:2014-06-01 00:00:00
abstract::Although limb swelling is a well-known complication of vaccination, its rarity and wide band of differential diagnosis of limb swelling make it a diagnostic challenge. In this case report, we describe three cases of vaccine-induced myositis with intramuscular sterile abscess formation in patients with limb swelling an...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-015-2242-1
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE:To present the prevalence, clinical relevance, and ultrasound (US) and magnetic resonance imaging (MRI) appearances of the accessory coracobrachialis (ACB) muscle. MATERIALS AND METHODS:We present an US prospective study of the ACB muscle over a 2-year period. Five of the eight patients with suspected ACB on...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-015-2153-1
更新日期:2015-09-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to use morphological as well as biochemical (T2 and T2* relaxation times and diffusion-weighted imaging (DWI)) magnetic resonance imaging (MRI) for the evaluation of healthy cartilage and cartilage repair tissue after matrix-associated autologous chondrocyte transplantation (MACT) of...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-009-0682-1
更新日期:2009-08-01 00:00:00
abstract:OBJECTIVE:The reliability of radiographic measurements has been studied in pediatric hips, but less has been published on the adult hip, and none have examined the reliability of measurements for the location of the center of rotation (COR) of the hip joint. We have investigated the reliability of various radiographic ...
journal_title:Skeletal radiology
pub_type: 临床试验,杂志文章
doi:10.1007/s00256-015-2101-0
更新日期:2015-07-01 00:00:00
abstract:: ...
journal_title:Skeletal radiology
pub_type:
doi:10.1007/s00256-018-2997-2
更新日期:2018-12-01 00:00:00
abstract::A 23-year-old woman with a medical history significant for tuberous sclerosis presented with symptoms of postpartum endometritis. Focal gigantism of the third digit of her right hand was incidentally noted and is reported to be a rare manifestation of tuberous sclerosis. ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s002560050486
更新日期:1999-02-01 00:00:00
abstract::The case of a 58-year-old man with a normal immune status with primary localized skeletal cryptococcosis of the right tibia was presented. Radiologically it appeared as an osteolytic lesion with marginally indistinct borders in the epimetaphyseal region of the proximal tibia. Histologically, necrotizing granulomatous ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00241838
更新日期:1992-01-01 00:00:00
abstract:OBJECTIVE:To review the imaging findings, age and gender distribution of chondroblastoma of the hands and feet. DESIGN AND PATIENTS:Twenty-five cases of pathologically proven chondroblastoma of the hands and feet were reviewed. Available imaging modalities included radiographs (n=24), CT (n=3), MRI (n=5), and radionuc...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-004-0762-1
更新日期:2004-10-01 00:00:00
abstract::With the growing number of orthopedic reconstructive spinal procedures, the use of bone grafting has steadily increased in the past decade. An understanding of the biology of bone grafting is essential for both the clinician and radiologist. Despite the advent of computed tomography and magnetic resonance imaging, con...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00241813
更新日期:1992-01-01 00:00:00
abstract:OBJECTIVE:The transverse relaxation time (T2) in MR imaging has been identified as a potential biomarker of hyaline cartilage pathology. This study investigates whether MR assessments of T2 are comparable between 3-T scanners from three different vendors. DESIGN:Twelve subjects with symptoms of knee osteoarthritis and...
journal_title:Skeletal radiology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00256-012-1511-5
更新日期:2013-04-01 00:00:00