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Collagen based polyurethanes—A review of recent advances and perspective.

Abstract：

:Collagen is mostly found in fibrous tissues such as tendons, ligaments and skin. Collagen makes up approximately 30% of the proteins within the body. These are tough and strong structures found all over the body: in bones, tendons and ligaments. Collagen being the most abundant protein provides tensile strength via cell matrix interactions to tissue architecture. Biomimetic materials of collagen origin gained wide spread acceptance in clinical applications. Vitamin C deficiency causes scurvy a serious and painful disease in which defective collagen prevents the formation of strong connective tissue, gums deteriorate and bleed, with loss of teeth; skin discolors, and wounds do not heal. Effective collagens prevent the manifestation of such disorders. Polyurethanes on the other hand are frequently used for various applications as they offered in wide-ranging of compositions, properties and complex structures. Collagen/PU bio-composites have potential array for biomedical applications. Considering versatile properties of the elongated fibrils and wide industrial and biomedical applications including biocompatibility of polyurethane, this review shed a light on collagen based polyurethane materials with their potential applications especially focusing the bio-medical field.

journal_name

Int J Biol Macromol

journal_title

International journal of biological macromolecules

authors

Zuber M,Zia F,Zia KM,Tabasum S,Salman M,Sultan N

doi

10.1016/j.ijbiomac.2015.07.001

subject

Has Abstract

pub_date

2015-09-01 00:00:00

pages

366-74

eissn

0141-8130

issn

1879-0003

pii

S0141-8130(15)00462-6

journal_volume

80

pub_type

杂志文章,评审

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