Abstract:
PURPOSE:To evaluate safety and efficacy of intravenous pulse cyclophosphamide (CyP) in acute macular serpiginous choroiditis (SC). METHODS:Patients with acute macular SC with lesions threatening and/or involving fovea were enrolled. All patients received CyP (1 g/m2) for 3 days followed by high-dose oral steroids (1.5 mg/kg) tapered over 6 months and monitored for visual acuity, response to treatment and systemic side effects. RESULTS:Eight patients (seven unilateral and one bilateral) with median age of 27 years (range: 13-40 years) were recruited. Mean visual acuity at presentation was 0.71 ± 0.35 logarithm of the minimum angle of resolution while postpulse visual acuity was 0.40 ± 0.32. Final mean visual acuity at 1-year was 0.31 ± 0.23 (P ≤ 0.05). Three eyes had recurrence and 3 patients developed transient hair loss with no other adverse effect. CONCLUSION:Intravenous CyP provides rapid resolution of lesion activity and thereby helps in maintaining good functional acuity.
journal_name
Indian J Ophthalmoljournal_title
Indian journal of ophthalmologyauthors
Venkatesh P,Gogia V,Gupta S,Tayade A,Shilpy N,Shah BM,Guleria Rdoi
10.4103/0301-4738.158070subject
Has Abstractpub_date
2015-04-01 00:00:00pages
318-22issue
4eissn
0301-4738issn
1998-3689pii
IndianJOphthalmol_2015_63_4_318_158070journal_volume
63pub_type
杂志文章abstract:AIM:To evaluate the management outcomes amongst various treatment modalities for submacular hemorrhage (SMH) in Indian subjects. SETTINGS AND DESIGN:Retrospective, single-center study. MATERIALS AND METHODS:Patients presenting with SMH between 1999 and 2006 were included. Treatment modalities included: vitrectomy wit...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.103779
更新日期:2012-11-01 00:00:00
abstract:Purpose:To analyse topographic and tomographic changes in fellow eyes of unilateral keratoconus patients by comparing them with normal eyes. Methods:This five-year retrospective observational comparative case study included 15 advanced keratoconus eyes of unilateral keratoconus (KCN group), 15 normal fellow eyes of un...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_2129_19
更新日期:2020-11-01 00:00:00
abstract::Gene therapy is a novel form of drug delivery that enlists the synthetic machinery of the patient's cells to produce a therapeutic agent. Genes may be delivered into cells in vitro or in vivo utilising viral or non-viral vectors. Recent technical advances have led to the demonstration of the molecular basis of various...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,评审
doi:
更新日期:2002-09-01 00:00:00
abstract::Macular involvement is commonly seen in cases with X-linked retinoschisis (XLRS) which includes foveal schisis and cystic maculopathy. Although no definitive treatment has been described, the use of topical 2% dorzolamide hydrochloride in such cases has shown varied response. We herein report a case of XLRS with fovea...
journal_title:Indian journal of ophthalmology
pub_type:
doi:10.4103/ijo.IJO_2061_19
更新日期:2020-07-01 00:00:00
abstract:Purpose:To objectively evaluate surgically induced astigmatism (SIA) after phacotrabeculectomy using keratometry and topography and to compare the magnitude of SIA and the refractive outcomes of single-site and twin-site phacotrabeculectomies. Methods:Forty prospective subjects were enrolled in the study and were rand...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_588_19
更新日期:2020-04-01 00:00:00
abstract:PURPOSE:To study the time course of interface healing and its correlation with visual acuity, modulation transfer function (MTF), and aberrations after myopic small-incision lenticule extraction (SMILE) correction. METHODS:Seventy-eight eyes of 78 patients (1 eye per patient) with a mean age of 25.7 years and mean sph...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_775_17
更新日期:2018-02-01 00:00:00
abstract:PURPOSE:To evaluate intraoperative complications during phacoemulsification of intumescent cataract using lens decompression technique. METHODS:Participants with intumescent cataract scheduled for phacoemulsification were recruited and divided into two groups. In both groups, after the anterior capsule was stained wit...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_352_17
更新日期:2017-12-01 00:00:00
abstract:Purpose:To analyze the outcome of cataract surgery in patients with ocular tuberculosis (OTB). Methods:Medical records of patients with OTB who underwent cataract surgery between 2005 and 2018 were retrospectively reviewed. The primary outcome measure was corrected distant visual acuity (CDVA), and a good outcome was ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_428_20
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:The effect of hypothyroidism on the choroidal thickness (CT) was investigated in patients with subclinical hypothyroidism and overt hypothyroidism, and biochemically and clinically euthyroid patients receiving levothyroxine treatment. The patients were compared with healthy subjects. MATERIALS AND METHODS:One ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.156976
更新日期:2015-03-01 00:00:00
abstract:PURPOSE:1. To determine the anatomical site and underlying causes of severe visual impairment and blindness in children in special education in Andhra Pradesh, India. 2. To compare the causes of blindness in two different regions in the state. 3. To evaluate improvement with correction of refractive error and low-visio...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:2000-09-01 00:00:00
abstract::The presently employed procedure of radial keratotomy is essentially unchanged from that developed by Fyodorov and introduced into the United States by Bores in 1978. The surgical procedure essentially consists of six basic steps: 1) application of appropriate anesthesia; 2) marking the visual axis; 3) marking the opt...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,评审
doi:
更新日期:1990-07-01 00:00:00
abstract:Purpose:To evaluate the feasibility and safety of heads-up three-dimensional (3D) vision system for phacoemulsification and intraocular lens (IOL) implantation surgery. Methods:In this prospective, randomized controlled study, 20 eyes with age-related cataract received phacoemulsification and IOL implantation and were...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.4103/ijo.IJO_1012_18
更新日期:2019-03-01 00:00:00
abstract:PURPOSE:To compare the outcome of Collagen cross-linking (CXL) with that following topography-guided customized ablation treatment (T-CAT) with simultaneous CXL in eyes with progressive keratoconus. MATERIALS AND METHODS:This was a prospective, non-randomized single centre study of 66 eyes with progressive keratoconus...
journal_title:Indian journal of ophthalmology
pub_type: 临床试验,杂志文章
doi:10.4103/0301-4738.111209
更新日期:2014-02-01 00:00:00
abstract::Iris cyst excision involves complex surgical maneuvers and may have a variable visual outcome depending upon preexisting and postoperative complications. Hereby, we report a case series of 10 eyes from which posttraumatic iris cysts were excised and proven histopathologically. Histopathology records were reviewed. Dat...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.43383
更新日期:2008-11-01 00:00:00
abstract::Pneumatic retinopexy (PR) is an alternative to scleral buckling for the surgical repair of selected retinal detachments. A gas bubble is injected into the vitreous cavity, and the patient is positioned so that the bubble closes the retinal break (s), allowing absorption of the subretinal fluid. Cryotherapy or laser ph...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,评审
doi:
更新日期:1996-09-01 00:00:00
abstract::Differentiating optic disc edema (ODE) from pseudo optic disc edema (PODE) continues to pose a diagnostic dilemma. Current report highlights the role of multicolor imaging (MC) in differentiating ODE from PODE. Composite multicolor images of the disc in ODE show greenish hyperreflectance that extends beyond the optic ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_473_17
更新日期:2017-11-01 00:00:00
abstract::In this case report, we demonstrate the use of optical coherence tomography angiography (OCTA) as a tool to evaluate intrinsic vasculature in a case of juxtapapillary melanoma which underwent ruthinium.106 plaque brachytherapy. In this case, OCTA could demonstrate a decrease in caliber and density of the intrinsic vas...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_1928_18
更新日期:2019-12-01 00:00:00
abstract:PURPOSE:To correlate fixation stability and retinal sensitivity measured by liquid crystal display (LCD) microperimetry to visual acuity in eyes with macular pathology. DESIGN:Retrospective chart review METHODS:The cohort included 26 eyes of 26 patients, divided into two groups according to visual acuity (Group 1 eye...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:2004-12-01 00:00:00
abstract:: ...
journal_title:Indian journal of ophthalmology
pub_type: 评论,信件
doi:10.4103/ijo.IJO_1124_18
更新日期:2019-01-01 00:00:00
abstract:Purpose:The purpose of the study was to analyze the correlation between central field index (CFI) and activity limitation in glaucoma using glaucoma activity limitation-9 (GAL-9) questionnaire. Methods:This hospital-based, cross-sectional, noninterventional study, included 50 patients diagnosed with glaucoma, with fie...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_295_18
更新日期:2018-08-01 00:00:00
abstract:PURPOSE:The aim of this study was to explore the possibilities of acceptance of a ready-to-dispense spherical equivalent (SE) of spherocylindrical (SC) correction spectacles in rural India. METHODS:Snellen visual acuity with SE power of refracted SC lenses was prospectively collected from all individuals visiting visi...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.4103/ijo.IJO_819_16
更新日期:2017-08-01 00:00:00
abstract:Purpose:To evaluate the frequency and the association of Thrombospondin 1 (THBS1) gene single nucleotide polymorphisms (SNPs) in Asian Indian patients with optical full thickness corneal grafting surgery. Methods:Prospective case-control analysis of optical penetrating keratoplasty patients with and without immune rej...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_552_19
更新日期:2020-04-01 00:00:00
abstract:AIM:To study the effect of treatment on vision-related quality of life (VR-QOL) in uveitis patients. MATERIALS AND METHODS:Interviewer-administered questionnaire-based evaluation of visual function and VR-QOL in Tamil-speaking adult patients with active uveitis at presentation and follow-up by the same interviewer. R...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.39662
更新日期:2008-07-01 00:00:00
abstract::Fibrous histiocytoma (FH) commonly occurs in the superficial layers of the skin. Orbit and limbus are documented ophthalmic sites of involvement but isolated corneal FH has never been reported in literature. We present the first case of FH exclusively involving the cornea where a 10-year-old male child presented with ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_1648_18
更新日期:2019-12-01 00:00:00
abstract::Anterior segment infiltration in acute myeloid leukemia (AML) presenting as hypopyon uveitis is very rare. We report this case as an uncommon presentation in a patient on remission after bone marrow transplant for AML. In addition to the hypopyon, the patient presented with "red eye" caused by ocular surface disease d...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.83621
更新日期:2011-09-01 00:00:00
abstract:Purpose:To compare and study the clinical outcome of tarsorrhaphy and amniotic membrane transplant in the healing of persistent corneal epithelial defects in terms of clinical improvement and symptomatic relief. Methods:This was an interventional, prospective study in which a total of 60 patients with persistent epith...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_617_19
更新日期:2020-01-01 00:00:00
abstract:PURPOSE:To report our experience with the diagnosis and management of Familial Exudative Vitreoretinopathy (FEVR) in a predominantly older Indian population.. METHODS:This prospective interventional non-comparative case series included 38 patients of FEVR and their 23 family members. The diagnosis was established by c...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:2003-12-01 00:00:00
abstract:Purpose:To report endoscope-assisted fascia lata harvest (EAFH) as a minimally-invasive technique for correction of severe blepharoptosis. Methods:This was a retrospective case series between January 2013 and April 2017. Medical records of all consecutive patients who underwent frontalis suspension by EAFH in the stud...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_819_17
更新日期:2018-03-01 00:00:00
abstract:Purpose:The purpose of the study is to report the outcomes of simultaneous cataract extraction (CE) and a new nonvalved glaucoma drainage device (GDD), Aurolab Aqueous Drainage Implant (AADI), in eyes with cataract and refractory glaucoma. Methods:This was a non-comparative, interventional, retrospective study. Consec...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_195_18
更新日期:2018-09-01 00:00:00
abstract::An unidentified nematode in the retina of an otherwise healthy young lady causing inflammation and exudation is reported. The worm was destroyed by Xenon photocoagulation, There was complete recovery and remarkable improvement in visual acuity. ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1990-10-01 00:00:00