当前位置： SCI文献检索 > ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY期刊下所有文献 > β-N-methylamino-L-alanine (BMAA) metabolism in the aquatic macrophyte Ceratophyllum demersum.

β-N-methylamino-L-alanine (BMAA) metabolism in the aquatic macrophyte Ceratophyllum demersum.

Abstract：

:The cyanobacterial neurotoxin, β-N-methylamino-l-alanine (BMAA) bioaccumulates and biomagnifies within the environment. However, most reports on the environmental presence of BMAA focus on the presence of BMAA in animals rather than in plants. Various laboratory studies have reported that this neurotoxin, implicated in neurodegenerative disease, is rapidly taken up by various aquatic and terrestrial plants, including crop plants. In this study the metabolism of BMAA in the aquatic macrophyte, Ceratophyllum demersum, was investigated using stable isotopically labelled BMAA. Data show that the toxin is rapidly removed from the environment by the plant. However, during depuration cellular BMAA concentrations decrease considerably, without excretion of the toxin back into the environment and without catabolism of BMAA, evidenced by the absence of label transfer to other amino acids. This strongly suggests that BMAA is metabolised via covalent modification and sequestered inside the plant as a BMAA-derivative. This modification may be reversed in humans following consumption of BMAA-containing plant material. These data therefore impact on the assessment of the risk of human exposure to this neurotoxin.

journal_name

Ecotoxicol Environ Saf

journal_title

Ecotoxicology and environmental safety

authors

Downing S,Esterhuizen-Londt M,Grant Downing T

doi

10.1016/j.ecoenv.2015.05.022

subject

Has Abstract

pub_date

2015-10-01 00:00:00

pages

88-92

eissn

0147-6513

issn

1090-2414

pii

S0147-6513(15)00245-6

journal_volume

120

pub_type

杂志文章

相关文献

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY文献大全
  • Polychlorinated biphenyl pollution from shipbuilding in Nagasaki Bay, Japan.

    abstract：:Polychlorinated biphenyl (PCB) pollution from shipbuilding in Nagasaki Bay, Japan, was discussed by determining PCB concentrations in sediment, in water, and in biological samples. PCBs were detected in all samples, in which much higher concentrations, more than 10 micrograms/g, were found in three sediment samples wh...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/0147-6513(83)90089-1

    authors： Maruyama K,Sahrul M,Tanabe S,Tatsukawa R

    更新日期：1983-10-01 00:00:00

  • Microarray analysis of di-n-butyl phthalate and 17α ethinyl-oestradiol responses in three-spined stickleback testes reveals novel candidate genes for endocrine disruption.

    abstract：:Phthalate esters are plasticizers frequently found in wastewater effluents. Previous studies on phthalates have reported anti-androgenic activity in mammals, causing concerns of their potential effects on the reproduction of aquatic organisms. Another group of environmental endocrine disrupters, steroidal estrogens, a...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2015.09.039

    authors： Prokkola JM,Katsiadaki I,Sebire M,Elphinstone-Davis J,Pausio S,Nikinmaa M,Leder EH

    更新日期：2016-02-01 00:00:00

  • Responses of glutamate cysteine ligase and glutathione to oxidants in deer mice (Peromyscus maniculatus).

    abstract：:Sensitivities of a wildlife species, deer mice, to oxidants were evaluated. A single dose (1589 mg/kg body weight by intraperitoneal injection) of carbon tetrachloride, a typical hepatotoxicant, caused changes in GCL activity and GSH content in multiple organs of deer mice. Hepatic GCL activity and GSH content were de...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2009.02.008

    authors： Wu H,McBride TJ,Isanhart JP,Cox SB,Hooper MJ

    更新日期：2009-07-01 00:00:00

  • Ciliated Protozoa in marine pollution studies. A conspectus.

    abstract：:The ecological role of the marine ciliates is discussed with reference to the interaction of this group with contaminants. While the ciliates may be of some value in routine screening of potential toxins, simple laboratory bioassays are unlikely to be of predictive value in assessing threats to the marine environment....

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/0147-6513(83)90063-5

    authors： Parker JG

    更新日期：1983-04-01 00:00:00

  • Artificial light at night alter the impact of arsenic on microbial decomposers and leaf litter decomposition in streams.

    abstract：:Artificial light at night (ALAN, also known as light pollution) has been proved to be a contributor to environmental change and a biodiversity threat worldwide, yet little is known about its potential interaction with different metal pollutants, such as arsenic (As), one of the largest threats to aquatic ecosystems. T...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2019.110014

    authors： Pu G,Zeng D,Mo L,Liao J,Chen X,Qiu S,Lv Y

    更新日期：2020-03-15 00:00:00

  • Brevibacillus sp. KUMAs2, a bacterial isolate for possible bioremediation of arsenic in rhizosphere.

    abstract：:Arsenic (As) contamination of soil and water has been considered as a major global environmental issue during last few decades. Among the various methods so far reported for reclamation of As contaminated rhizosphere soil, bioremediation using bacteria has been found to be most promising. An As resistant bacterial iso...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2014.06.007

    authors： Mallick I,Hossain ST,Sinha S,Mukherjee SK

    更新日期：2014-09-01 00:00:00

  • A microfluidic surface-enhanced Raman spectroscopy approach for assessing the particle number effect of AgNPs on cytotoxicity.

    abstract：:Silver nanoparticles (Ag NPs) have well-known antibacterial properties and are widely applied in various medical products and general commodities. Although many studies have addressed the toxicity of Ag NPs to mammalian cells, the direct relationship between the number of Ag NPs in living cells and the corresponding c...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2018.07.026

    authors： Zhai Z,Nie M,Guan Y,Zhang F,Chen L,Muhammad,Du W,Liu G,Tian Y,Huang Q

    更新日期：2018-10-30 00:00:00

  • Acute and subchronic oral toxicity of fluoranthene in F-344 rats.

    abstract：:We have studied the acute and subchronic oral toxicity of fluoranthene (FLA) in male and female F-344 rats. Single acute FLA doses of 0, 1000, 2000, and 3000 mg/kg body weight (BW) dissolved in peanut oil were administered daily by oral gavage. Subchronic doses of 0, 150, 750, and 1500 mg FLA/kg BW/day were administer...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/S0147-6513(03)00110-6

    authors： Knuckles ME,Inyang F,Ramesh A

    更新日期：2004-09-01 00:00:00

  • Rapid and simultaneous analysis of tetrabromobisphenol A and hexabromocyclododecane in water by direct immersion solid phase microextraction: Uniform design to explore factors.

    abstract：:Direct immersion solid phase microextraction (DI-SPME) coupled to liquid chromatography-tandem mass spectrometry (LC-MS/MS) is of significant research interest because of its low solvent consumption, simple design, and efficient, sensitive, fast performance. In this work, a combination of these two methods (DI-SPME-LC...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2019.03.104

    authors： Yu Y,Zhu X,Zhu J,Li L,Zhang X,Xiang M,Ma R,Yu L,Yu Z,Wang Z

    更新日期：2019-07-30 00:00:00

  • Improved photoelectrocatalytic degradation of tetrabromobisphenol A with silver and reduced graphene oxide-modified TiO2 nanotube arrays under simulated sunlight.

    abstract：:In present study, reductive graphene oxide and silver nanoparticles co-comodified TiO2 nanotube arrays were prepared, and which was investigated to degrade tetrabromobisphenol A. The arrays co-modified with silver nanoparticles and reductive graphene oxide prepared by electrodeposition method exhibited good photoelect...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2019.109472

    authors： Zhou Q,Wang M,Tong Y,Wang H,Zhou X,Sheng X,Sun Y,Chen C

    更新日期：2019-10-30 00:00:00

  • Integrated effects of important environmental factors on arsenic biotransformation and photosynthetic efficiency by marine microalgae.

    abstract：:Microalgae play an important role in arsenic (As) bioaccumulation and biogeochemical cycling in marine ecosystems. Marine microalgal growth and As biotransformation processes depend on environmental factors, including salinity, temperature, and nutrient concentrations, and data in this regard are available in the lite...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2020.110797

    authors： Papry RI,Fujisawa S,Yinghan Z,Akhyar O,Al Mamun MA,Mashio AS,Hasegawa H

    更新日期：2020-09-15 00:00:00

  • Tissue repair: a critical determinant in CCl4 hepatotoxicity.

    abstract：:A single antimitotic dose of colchicine administered 24 hr after a single ip dose of CCl4 profoundly enhanced lethality in the adult Sprague-Dawley male rat from < 10% to over > or = 70% within the next 24 hr. These findings suggest that disruption of normal hepatic cellular repair processes is a critical factor affec...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1006/eesa.1994.1010

    authors： Calabrese EJ,Leonard DA,Baldwin LA

    更新日期：1994-02-01 00:00:00

  • Assisted phytoremediation of heavy metal contaminated soil from a mined site with Typha latifolia and Chrysopogon zizanioides.

    abstract：:Chemically assisted phytoremediation is fast gaining attention as a biotechnology to accelerate heavy metal removal from contaminated substrates, but how different chemical amendments affect the process remains an important research question. Here, bioaccumulation factor (BAF), translocation factor (TF), removal effic...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2017.10.014

    authors： Anning AK,Akoto R

    更新日期：2018-02-01 00:00:00

  • Adsorption-desorption behavior of benzobicyclon hydrolysate in different agricultural soils in China.

    abstract：:Benzobicyclon is a systemic herbicide that was officially registered in China in 2018. The environmental behaviors of benzobicyclon hydrolysate (BH), the main metabolite and active product of benzobicyclon, remain poorly understood in paddy fields. Here, agricultural soil samples were collected from paddy fields in Ji...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2020.110915

    authors： Rao L,Luo J,Zhou W,Zou Z,Tang L,Li B

    更新日期：2020-10-01 00:00:00

  • Risk assessment of three fluoroquinolone antibiotics in the groundwater recharge system.

    abstract：:Three fluoroquinolone antibiotics agents (FQs) in groundwater and reclaimed water have been investigated in Changzhou and Beijing, China. The occurrence of ofloxacin (OFL), enrofloxacin (ENR) and norfloxacin (NOR) is in nanograms per liter and has 100% frequency. The concentration order of FQs in reclaimed water is NO...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2016.05.030

    authors： Chen G,Liu X,Tartakevosky D,Li M

    更新日期：2016-11-01 00:00:00

  • Possible side effects of airborne pesticides on fungi and vascular plants in The Netherlands.

    abstract：:A survey of the potential side effects of volatilized pesticides on fungi and vascular plants in The Netherlands has been made for two herbicides (atrazine and MCPA), a fungicide (captan) and a soil fumigant (metham sodium). By applying existing models, a prediction is presented of post-treatment dispersal and deposit...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1006/eesa.1995.1009

    authors： de Jong FM,van der Voet E,Canters KJ

    更新日期：1995-02-01 00:00:00

  • Toxicity assessment of synthesized titanium dioxide nanoparticles in fresh water algae Chlorella pyrenoidosa and a zebrafish liver cell line.

    abstract：:This study aims to assess the toxicity of the commonly-spread titanium dioxide nanoparticles (TiO2 NPs) by evaluating the exposure impact of the particles on both freshwater algae Chlorella pyrenoidosa and zebrafish liver cell line (ZFL), the two common in vitro models in toxicological studies. To compare the toxic ef...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2021.111948

    authors： Al-Ammari A,Zhang L,Yang J,Wei F,Chen C,Sun D

    更新日期：2021-01-21 00:00:00

  • Mineral elements uptake and physiological response of Amaranthus mangostanus (L.) as affected by biochar.

    abstract：:Amaranthus mangostanus L. (amaranth) was hydroponically grown in different concentrations of biochar amended nutrient solution to investigate the mineral elements migration and physiological response of amaranth as affected by biochar. Our results showed that exposure to 26.6 g/L of biochar greatly increased the root ...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2019.03.039

    authors： Jia W,Wang C,Ma C,Wang J,Sun H,Xing B

    更新日期：2019-07-15 00:00:00

  • Cardio-respiratory function and oxidative stress biomarkers in Nile tilapia exposed to the organophosphate insecticide trichlorfon (NEGUVON).

    abstract：:The cardio-respiratory function, oxidative stress and fish antioxidants were analyzed in juvenile Nile tilapia exposed for 96 h to a sublethal trichlorfon (TRC-Neguvon, Bayer) concentration of 0.5 mg L(-1). The exposure to TRC induced oxidative stress in the heart, as manifested by the glutathione S-transferase deplet...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2008.11.003

    authors： Thomaz JM,Martins ND,Monteiro DA,Rantin FT,Kalinin AL

    更新日期：2009-07-01 00:00:00

  • Distribution and accumulation of [2,3-14C]acrylonitrile in rat after single injection.

    abstract：:The distribution and accumulation of acrylonitrile after the single i.p. injection of [2,3-14C]acrylonitrile were examined by whole-body autoradiography and by the determination of 14C radioactivities in several tissues and subcellular fractions after a whole-body perfusion. 14C Radioactivity was seen strongly in bloo...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/0147-6513(82)90030-6

    authors： Sato M,Hirasawa F,Ogata M,Takizawa Y,Kojima H,Yoshida T

    更新日期：1982-10-01 00:00:00

  • Effects of various warming patterns on Cd transfer in soil-rice systems under Free Air Temperature Increase (FATI) conditions.

    abstract：:Global warming has become an important research topic in different disciplines around the world, especially in the fields of environment quality and food security. As a potential problem in soil environments, cadmium (Cd) contamination of rice under global warming conditions has not been thoroughly investigated. In th...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2018.10.047

    authors： Ge L,Cang L,Ata-Ul-Karim ST,Yang J,Zhou D

    更新日期：2019-01-30 00:00:00

  • Soil pollution and toxicity in an area affected by emissions from a bauxite processing plant and a power plant in Gardanne (southern France).

    abstract：:Soil pollution and toxicity have been investigated in the Gardanne area (southern France) at a range of sites around a recognized pollution source, a bauxite processing plant (BPP), and a power plant (PP). Soil samples were submitted to inorganic and organic analyses and tested for toxicity in two invertebrate models....

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2018.11.122

    authors： Oral R,Pagano G,Siciliano A,Toscanesi M,Gravina M,Di Nunzio A,Palumbo A,Thomas PJ,Tommasi F,Burić P,Lyons DM,Guida M,Trifuoggi M

    更新日期：2019-04-15 00:00:00

  • Sobol sensitivity approach for the appraisal of geomedical health risks associated with oral intake and dermal pathways of groundwater fluoride in a semi-arid region of south India.

    abstract：:The main objective of the present investigation is appraisal of human health hazard based on the intake and dermal contact of fluoride enriched potable groundwater used for rural water supply in a semi-arid region (Shanmuganadhi River basin) of south India. A variance decomposition based Sobol sensitivity method was u...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2020.110438

    authors： Karunanidhi D,Aravinthasamy P,Kumar D,Subramani T,Roy PD

    更新日期：2020-05-01 00:00:00

  • Astilbin protects chicken peripheral blood lymphocytes from cadmium-induced necroptosis via oxidative stress and the PI3K/Akt pathway.

    abstract：:Astilbin (ASB), a dihydroflavonol glycoside, is widely found in a variety of plants and in functional foods and acts as a powerful antioxidant. The aim of this study was to investigate the underlying mechanisms involved in the antagonistic effects of ASB on cadmium (Cd)-induced necroptosis in chicken peripheral blood ...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2019.110064

    authors： Xin C,Guangliang S,Qing Z,Qingqing L,Hang Y,Yiming Z,Shu L

    更新日期：2020-03-01 00:00:00

  • Responses of fish populations and communities to pulp mill effluents: a holistic assessment.

    abstract：:Fish populations residing in a river receiving bleached kraft mill effluents (BKME) and in an uncontaminated river were investigated to evaluate causal relationships between exposure to BKME and various indicators of fish health. The Index of Biotic Integrity demonstrated that species richness and composition were muc...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/0147-6513(92)90011-q

    authors： Adams SM,Crumby WD,Greeley MS Jr,Shugart LR,Saylor CF

    更新日期：1992-12-01 00:00:00

  • Genotoxicity biomarkers' association with B(a)P biotransformation in Dicentrarchus labrax L.

    abstract：:Dicentrarchus labrax (sea bass) were exposed during 0, 4, 8, 16, 24, 48, and 96 h to 0 and 0.1 microM benzo(a)pyrene (B(a)P), an environmental pollutant, and the following biomarkers were measured: (1) liver cytochrome P450 (P450) content and ethoxyresorufin-O-deethylase (EROD) activity as phase I biotransformation pa...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/s0147-6513(02)00070-2

    authors： Gravato C,Santos MA

    更新日期：2003-07-01 00:00:00

  • Biodegradation of phenol by a highly tolerant strain Rhodococcus ruber C1: Biochemical characterization and comparative genome analysis.

    abstract：:A novel phenol-degrading strain was isolated and identified as Rhodococcus ruber C1. The degradation analysis shows that 1806 mg/L of phenol can be completely degraded by strain C1 within 38 h, and the maximum specific growth rate (μmax=1.527 h-1) and maximum specific phenol degradation rate (qmax=3.674 h-1) indicate ...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2020.111709

    authors： Zhao T,Gao Y,Yu T,Zhang Y,Zhang Z,Zhang L,Zhang L

    更新日期：2021-01-15 00:00:00

  • The effect of salinity and alkalinity on growth and the accumulation of copper and zinc in the Chlorophyta Ulva fasciata.

    abstract：:Copper and zinc accumulation in macroalgae is a complex issue. While these metals exist as micronutrients and can serve to add nutritional value to the macroalgae when consumed by both plants and animals, elevated levels of the metals can reduce growth or even kill the algae. Many water parameters can influence the to...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2019.01.088

    authors： Geddie AW,Hall SG

    更新日期：2019-05-15 00:00:00

  • Bioaccumulation, oxidative stress and genotoxicity in fish (Channa punctatus) exposed to a thermal power plant effluent.

    abstract：:Metal bioaccumulation and induction of biomarkers such as lipid peroxidation (LPO), superoxide dismutase (SOD), catalase (CAT), glutathione S transferase (GST), reduced glutathione (GSH) and DNA damage are potential indicators of stress in Channa punctatus exposed to effluents. In canal water, receiving thermal power ...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2016.01.007

    authors： Javed M,Ahmad I,Usmani N,Ahmad M

    更新日期：2016-05-01 00:00:00

  • Toxicity of organotin compounds on embryos of a marine invertebrate (Styela plicata; tunicata).

    abstract：:In order to clarify the interaction mechanism between organotin compounds and organisms, the effects of these compounds on the development of a benthonic filter-feeding invertebrate were studied. Embryos of the ascidian Styela plicata were obtained in laboratory by cross-fertilization and their development was followe...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1006/eesa.1996.0097

    authors： Cima F,Ballarin L,Bressa G,Martinucci G,Burighel P

    更新日期：1996-11-01 00:00:00