Abstract:
:The main objective of the present investigation is appraisal of human health hazard based on the intake and dermal contact of fluoride enriched potable groundwater used for rural water supply in a semi-arid region (Shanmuganadhi River basin) of south India. A variance decomposition based Sobol sensitivity method was used to assess the relative contribution as well as interaction of input variables for both oral and dermal models. Three different scores were evaluated: FOE (first order effect), SOE (second order effect) and TE (total effect) for different age groups of population including gender (kids, women and men). The spatio-temporal mapping indicates that about 26% of water supply wells exceeded the recommended limit (WHO) of fluoride (>1.5 mg l-1) for safe intake. These wells spread over 104.03 km2 area consisting 16 villages in the basin. To assess the human health risk related to fluoride enrichment in potable water, hazard index (HI) was calculated as per USEPA guidelines. The non-carcinogenic risk based on oral intake ranges from 0 to 1.81, from 0 to 1.59 and from 0 to 1.29 for kids, women and men respectively. Nearly 30%, 21% and 12% of well samples exceeded the upper permissible limit (HI > 1) for kids, women and men respectively. The Sobol sensitivity analysis reveals that, Cw (concentration of F- in water) and IR (intake rate) combination plays a vital role in the HQ oral model for the appraisal of health hazard in kids. However, these two parameters have negligible effect on health hazard for adult population (men and women). Therefore, lower age group people especially kids have significant ill effect due to the consumption of fluoride enriched potable water. The model output suggests that body weight (BW) has least effect on health hazard in the lower age group of population. Interestingly 'exposure frequency (EF)' and 'body weight (BW)' have not much effect on health hazards related to dermal contact, and 'skin surface area (SA)' has minimal effect for men (TE = 0.92) and women (TE = 1.26). However, 'SA' has vital effect for kids (TE = 17.39). Because of this, older age group people have more dermal risk than the younger people. Therefore, the HQ dermal results indicate that 49%, 64% and 67% of samples possess non-carcinogenic risk to the kids, women and men respectively.
journal_name
Ecotoxicol Environ Safjournal_title
Ecotoxicology and environmental safetyauthors
Karunanidhi D,Aravinthasamy P,Kumar D,Subramani T,Roy PDdoi
10.1016/j.ecoenv.2020.110438subject
Has Abstractpub_date
2020-05-01 00:00:00pages
110438eissn
0147-6513issn
1090-2414pii
S0147-6513(20)30277-3journal_volume
194pub_type
杂志文章abstract::Urban emissions are a major contributor to atmospheric Hg budgets. Continuous measurements of total gaseous mercury (TGM) and particulate-bound mercury (PHg) in PM2.5 were conducted from October 2015 to July 2016 in a metropolis, Jinan, in eastern China. Average TGM and PHg concentrations were 4.91 ± 3.66 ng m-3 and 4...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2020.110541
更新日期:2020-06-15 00:00:00
abstract::In situ bioassays are becoming very popular for laboratory test validation and field extrapolation. Natural conditions, including environmental variables, affect the "behavior" of contaminants and, consequently, their toxicity. This work aimed to develop protocols for in situ chronic bioassays with cladocerans and to ...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1006/eesa.2000.1926
更新日期:2000-09-01 00:00:00
abstract::Air pollution exposure has been associated with hypertension, but limited studies have examined the associations in diabetic patients. We aimed to examine the associations of exposure to air pollution with blood pressure in diabetic patients. We identified patients who were previously diagnosed as type-2 diabetes mell...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2018.12.069
更新日期:2019-04-30 00:00:00
abstract::Since development of antioxidant defence system is high energy demanding event, innate defence system and stress tolerance of plant is strictly governed by plant age. This study is aimed towards evaluating variation of tolerance in germinating seeds and seedlings of Oryza sativa L. cv. Swarna against nano-scale zero v...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2020.111104
更新日期:2020-11-01 00:00:00
abstract::Acid rain is a global environmental problem. Acid rain can affect plants directly by damaging the leaves and indirectly by soil acidifying. Many studies have been conducted to investigate the impacts of acid rain on plant under a single soil type. However, there is little information on the effect of acid rain on plan...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2019.109705
更新日期:2019-12-15 00:00:00
abstract::The interaction between multi-walled carbon nanotubes (MWCNTs) and soil heavy metals was rarely studied. With the convenience of detecting multiple metal elements by ICP-AES, this paper examined the potential effectiveness of MWCNTs on extractability of antimony (Sb) and cadmium (Cd) in contaminated soil. Three-step s...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2020.111316
更新日期:2020-12-01 00:00:00
abstract::Nonylphenol (NP) has been classified as an endocrine-disrupting chemical. In this study, we conducted mysid DNA microarray analysis with which has 2240 oligo DNA probes to observe differential gene expressions in mysid crustacean (Americamysis bahia) exposed to 1, 3, 10 and 30 μg/l of NP for 14 days. As a result, we f...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2016.07.037
更新日期:2016-11-01 00:00:00
abstract::The effects of decabromodiphenyl ether (BDE-209) on avoidance response, survival, growth, and reproduction of earthworms (Eisenia fetida) were investigated under laboratory conditions using natural and artificial soils as substrate. Results showed that no significant avoidance response was observed when earthworms wer...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2012.12.009
更新日期:2013-04-01 00:00:00
abstract::Bisphenol A (BPA) is widely distributed in the environment and human surroundings and is closely related to the occurrence of many chronic diseases including female infertility. Although BPA-induced granulosa cell apoptosis has been widely reported, the underlying mechanisms remain unknown. In this study, we evaluated...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2020.111429
更新日期:2021-01-15 00:00:00
abstract::The microbiome in artificial lake water and its impact on mercury (Hg) methylation remain largely unknown. We selected the largest artificial lake in southeastern china, Changshou Lake (CSL), which has high background levels of Hg, for our investigation of Hg transformation microorganisms. Five different sections of t...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2018.05.018
更新日期:2018-09-30 00:00:00
abstract::Phytoremediation is an attractive approach for the cleanup of polycyclic aromatic hydrocarbons-contaminated soil. The joint effect of alfalfa and microorganisms, including Arthrobacter oxydans, Staphylococcus auricularis and Stenotrophomonas maltophilia, on pyrene removal was investigated. The results showed that the ...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2014.08.031
更新日期:2014-12-01 00:00:00
abstract::Although copper is among the indispensable trace elements in animal physiological processes, it exerts toxicity upon over-exposure. The present study aimed to investigate hepatocyte autophagy induced by CuSO4 and its potential mechanism. A total of 240 ICR mice (four-week-old, 120 males and 120 females) were randomly ...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2020.111656
更新日期:2021-01-15 00:00:00
abstract::This study was conducted with the aim of analyzing persistent organic pollutants i.e., PCBs, PBDEs, DPs and OCPs for sediment samples collected from Mehmood Booti Drain, Lahore, Pakistan that receives higher pollution loads from adjacent waste dumping site. Levels of ∑PCBs, ∑PBDEs, ∑DPs and ∑OCPs ranged between 5.9-62...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2015.11.019
更新日期:2016-03-01 00:00:00
abstract::Prenatal life exposure to fine particulate matter (aerodynamic diameter less than or equal to 2.5 µm, PM2.5) has been linked with increased risk of adverse fetal development and birth outcomes in previous studies. However, to our knowledge, no study has investigated the association of maternal PM2.5 with the risk of f...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2018.11.068
更新日期:2019-04-15 00:00:00
abstract::Amaranthus mangostanus L. (amaranth) was hydroponically grown in different concentrations of biochar amended nutrient solution to investigate the mineral elements migration and physiological response of amaranth as affected by biochar. Our results showed that exposure to 26.6 g/L of biochar greatly increased the root ...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2019.03.039
更新日期:2019-07-15 00:00:00
abstract::Heavy metals are ubiquitous environmental pollutants, and their toxic effects have been widely studied. However, their transgenerational effects between parent and progeny at environmental relevant concentrations need further investigations. Currently, L3 stage of Caenorhabditis elegans was exposed to aqueous metals (...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2012.11.012
更新日期:2013-02-01 00:00:00
abstract::In this study, mouthpart deformities in Chironomid larvae (Diptera) were investigated in relation to sediment contamination in the Shiroro Lake in Nigeria. Metals and chironomids were sampled monthly at three stations (A-C) between August 2013 and January 2014. Across the stations, zinc ranged (3.9-75mg/g), manganese ...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2017.10.074
更新日期:2018-03-01 00:00:00
abstract::Toxicities of the commercial insecticide formulations of azinphos methyl, chlorpyrifos, fenvalerate, and methyl parathion were evaluated in streamwater samples containing natural organic material (NOM) using a modification of a bacterial bioluminescence assay. Toxicity reduction of azinphos methyl was significantly (P...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1006/eesa.1995.1047
更新日期:1995-06-01 00:00:00
abstract::This study investigated the stress response of earthworms (Eisenia andrei) to exposure to a commonly used herbicide, 2,4 dichloro-phenoxy-acetic acid (2,4-D). We evaluated both stress biomarkers and the transcriptional expression levels and activity of three enzymes involved in oxidative stress responses. Earthworms w...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2015.07.014
更新日期:2015-12-01 00:00:00
abstract::Polycyclic aromatic hydrocarbons (PAHs) are widespread in various ecosystems and are pollutants of great concern due to their potential toxicity, mutagenecity and carcinogenicity. Surfactant has become a hot topic for its wide application in the bioremediation of PAHs. The aim of this work is to explore a microcalorim...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2013.08.012
更新日期:2013-12-01 00:00:00
abstract::A series of 22 chlorinated phenols was studied for their effects on photosynthesis of isolated chloroplasts. Each chlorophenol was an uncoupler, but the uncoupling activity depended upon substitution. The di-, tri-, or pentachloro substitution greatly enhanced the uncoupling activity. However, 2,6 substitution was not...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/0147-6513(87)90040-6
更新日期:1987-02-01 00:00:00
abstract::The vitellogenin (VTG) in fish has been used as an important biomarker for monitoring endocrine disrupting compounds (EDCs). This paper reports the development of a new monoclonal antibody (McAb) against the VTG of crucian carp (Carassius carassius). The McAb has a molecular weight of 149.4 kDa (heavy chain: 53.1 kDa;...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2005.11.005
更新日期:2007-02-01 00:00:00
abstract::The mortality of roach (Rutilus rutilus) embryos increased during the early embryonic phase following exposure to Al and acidity from pH 6.7 to 5.0. No roach hatched at pH<5.00 or at pH 5.00 in the presence of Al. By contrast, increased embryonic mortality in pike (Esox lucius) occurred mainly during and after the nor...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2004.03.005
更新日期:2004-06-01 00:00:00
abstract::Juvenile rainbow trout (Salmo gairdneri) were exposed to 100 ppb mercury (as HgCl2) in the water for 14 days. Concentrations of mercury in water and fish organs were monitored using radiolabeled mercury. Tissues from kidney and liver were fixed, and sections were developed by autometallography, a method whereby accumu...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/0147-6513(86)90018-7
更新日期:1986-12-01 00:00:00
abstract::Despite the potential emissions of heavy metal pollution in Lake Caizi due to extensive agriculture, urban growth and fishing activities, the risk posed by metal concentrations to aquatic environments and human populations has not yet been studied. In this study we compared the concentrations of Hg, As, Pb, Cd, Cr, Cu...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2018.03.078
更新日期:2018-08-15 00:00:00
abstract::The aim of this work was to study the removal of Cu (II) and U (VI) ions from aqueous solutions by encapsulating magnetic Fe3O4 nanoparticles into calcium alginate coated chitosan hydrochloride (CCM) hydrogel beads. ATR-FTIR and XRD analysis data indicated that the CCM composites were successfully prepared. SEM images...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2017.09.036
更新日期:2018-01-01 00:00:00
abstract::Mercury (Hg) and other heavy metal profiles, namely, lead (Pb), arsenic (As), cadmium (Cd), and selenium (Se) were investigated in maternal and umbilical cord (cord) red blood cells (RBCs) at parturition in Japanese population. Correlation coefficients of Hg, Pb, As, Cd, and Se between maternal and cord RBCs were 0.91...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2009.09.010
更新日期:2010-01-01 00:00:00
abstract::Soil acts as a repository for many metals that human activity releases into the environment. Cadmium enters agricultural soils primarily from application of phosphate fertilizers and sewage sludge. Among soil bacteria, rhizobia have a great agronomic and environmental significance and are major contributors to a susta...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2018.07.125
更新日期:2018-12-15 00:00:00
abstract::This study indicates that complex mixtures of pollutants found in the Arctic marine environment have genotoxic effects in glaucous gulls (Larus hyperboreus). DNA adducts were quantified, by the (32)P-postlabeling technique, in liver samples from gulls fed with hen eggs (controls) and from gulls fed with environmentall...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2004.12.023
更新日期:2005-11-01 00:00:00
abstract::Cistus monspeliensis L. is a species that grows spontaneously in contaminated mining areas of the Iberian Pyrite Belt. This species can accumulate high concentrations of As in the shoots without visible signs of phytotoxicity. In order to understand the physiological mechanisms underlying this tolerance, C. monspelien...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2018.12.098
更新日期:2019-04-30 00:00:00