Abstract:
:Mercury (Hg) and other heavy metal profiles, namely, lead (Pb), arsenic (As), cadmium (Cd), and selenium (Se) were investigated in maternal and umbilical cord (cord) red blood cells (RBCs) at parturition in Japanese population. Correlation coefficients of Hg, Pb, As, Cd, and Se between maternal and cord RBCs were 0.91, 0.79, 0.89, 0.31, and 0.76, respectively, and the respective means of cord/maternal RBCs ratios were 1.63, 0.52, 0.62, 0.12, and 1.18. These results indicate that fetal exposure to these metals (excluding Cd) strongly reflected each maternal exposure level. Among these metals, the placental transfer of methylmercury (MeHg) seemed to be extremely high but that of Cd to be limited. Hg showed positive correlations with Se in maternal RBCs but not in cord RBCs, and the Se/Hg molar ratio was lower in the latter, suggesting that the protective effects of Se against MeHg are less expected in fetuses than in mothers.
journal_name
Ecotoxicol Environ Safjournal_title
Ecotoxicology and environmental safetyauthors
Sakamoto M,Murata K,Kubota M,Nakai K,Satoh Hdoi
10.1016/j.ecoenv.2009.09.010subject
Has Abstractpub_date
2010-01-01 00:00:00pages
1-6issue
1eissn
0147-6513issn
1090-2414pii
S0147-6513(09)00206-1journal_volume
73pub_type
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