Fibromyalgia and related conditions.

Abstract:

:Fibromyalgia is the currently preferred term for widespread musculoskeletal pain, typically accompanied by other symptoms such as fatigue, memory problems, and sleep and mood disturbances, for which no alternative cause can be identified. Earlier there was some doubt about whether there was an "organic basis" for these related conditions, but today there is irrefutable evidence from brain imaging and other techniques that this condition has strong biological underpinnings, even though psychological, social, and behavioral factors clearly play prominent roles in some patients. The pathophysiological hallmark is a sensitized or hyperactive central nervous system that leads to an increased volume control or gain on pain and sensory processing. This condition can occur in isolation, but more often it co-occurs with other conditions now being shown to have a similar underlying pathophysiology (eg, irritable bowel syndrome, interstitial cystitis, and tension headache) or as a comorbidity in individuals with diseases characterized by ongoing peripheral damage or inflammation (eg, autoimmune disorders and osteoarthritis). In the latter instance, the term centralized pain connotes the fact that in addition to the pain that might be caused by peripheral factors, there is superimposed pain augmentation occurring in the central nervous system. It is important to recognize this phenomenon (regardless of what term is used to describe it) because individuals with centralized pain do not respond nearly as well to treatments that work well for peripheral pain (surgery and opioids) and preferentially respond to centrally acting analgesics and nonpharmacological therapies.

journal_name

Mayo Clin Proc

journal_title

Mayo Clinic proceedings

authors

Clauw DJ

doi

10.1016/j.mayocp.2015.03.014

subject

Has Abstract

pub_date

2015-05-01 00:00:00

pages

680-92

issue

5

eissn

0025-6196

issn

1942-5546

pii

S0025-6196(15)00243-8

journal_volume

90

pub_type

杂志文章,评审
  • Recent improvements in survival in primary systemic amyloidosis and the importance of an early mortality risk score.

    abstract:OBJECTIVE:To examine whether the outcome of patients with primary systemic amyloidosis (AL) has improved over time and to identify predictors of early mortality in patients with AL. PATIENTS AND METHODS:We studied 2 separate cohorts of patients. The first cohort, consisting of 1998 patients with AL seen at Mayo Clinic...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.4065/mcp.2010.0480

    authors: Kumar SK,Gertz MA,Lacy MQ,Dingli D,Hayman SR,Buadi FK,Short-Detweiler K,Zeldenrust SR,Leung N,Greipp PR,Lust JA,Russell SJ,Kyle RA,Rajkumar SV,Dispenzieri A

    更新日期:2011-01-01 00:00:00

  • Safety, diagnostic yield, and therapeutic implications of flexible bronchoscopy in patients with febrile neutropenia and pulmonary infiltrates.

    abstract:OBJECTIVE:To evaluate the safety, diagnostic yield, and therapeutic implications of flexible bronchoscopy with bronchoalveolar lavage (BAL) and transbronchial biopsy in patients with febrile neutropenia and pulmonary infiltrates. PATIENTS AND METHODS:We retrospectively reviewed the medical records of all patients with...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.4065/80.11.1414

    authors: Peikert T,Rana S,Edell ES

    更新日期:2005-11-01 00:00:00

  • Effect of Preprocedural Thrombocytopenia on Prognosis After Percutaneous Coronary Intervention.

    abstract:OBJECTIVE:To assess early and late outcomes, including bleeding, in patients with thrombocytopenia undergoing percutaneous coronary intervention (PCI). PATIENTS AND METHODS:We performed a retrospective single-center study of patients with preprocedural thrombocytopenia (platelet count ≤100,000/μL; n=204) undergoing PC...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/j.mayocp.2016.05.008

    authors: Raphael CE,Spoon DB,Bell MR,Psaltis PJ,Kidd S,Loh SX,Lennon RJ,Singh M,Rihal C,Gulati R

    更新日期:2016-08-01 00:00:00

  • Bedside estimation of risk from percutaneous coronary intervention: the new Mayo Clinic risk scores.

    abstract:OBJECTIVE:To derive risk models for percutaneous coronary intervention (PCI) outcomes from clinical and laboratory variables available before the procedure so they can be used for preprocedure risk stratification. PATIENTS AND METHODS:Using the Mayo Clinic registry, we analyzed 9035 PCIs on 7640 unique patients from J...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.4065/82.6.701

    authors: Singh M,Rihal CS,Lennon RJ,Spertus J,Rumsfeld JS,Holmes DR Jr

    更新日期:2007-06-01 00:00:00

  • Prosthetic joint infection due to Staphylococcus lugdunensis.

    abstract::Staphylococcus lugdunensis, a coagulase-negative staphylococcus, is being increasingly recognized as the cause of serious infections. We report 2 cases of total knee arthroplasty infection caused by S lugdunensis. S lugdunensis frequently produces a clumping factor that can result in a positive slide (short) coagulase...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.4065/75.5.511

    authors: Sampathkumar P,Osmon DR,Cockerill FR 3rd

    更新日期:2000-05-01 00:00:00

  • Separate Effects of Intensity and Amount of Exercise on Interindividual Cardiorespiratory Fitness Response.

    abstract:OBJECTIVE:To determine the separate effects of exercise intensity and amount on interindividual cardiorespiratory fitness (CRF) response. PARTICIPANTS AND METHODS:Participants were 121 (75 females, 62%) sedentary, middle-aged (mean [SD] age, 53.2 [7.5] years), abdominally obese adults who completed at least 90% of 5 w...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.mayocp.2015.07.024

    authors: Ross R,de Lannoy L,Stotz PJ

    更新日期:2015-11-01 00:00:00

  • The Impact of a 20-Minute Animal-Assisted Activity Session on the Physiological and Emotional States in Patients With Fibromyalgia.

    abstract:OBJECTIVE:To study the direct physiological and emotional impact of an animal-assisted activity (AAA) session (a form of complementary and integrative medicine) in patients with fibromyalgia (FM). PATIENTS AND METHODS:The study population consisted of 221 participants with FM who were attending Mayo Clinic's Fibromyal...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.mayocp.2020.04.037

    authors: Clark S,Martin F,McGowan RTS,Smidt J,Anderson R,Wang L,Turpin T,Langenfeld-McCoy N,Bauer B,Mohabbat AB

    更新日期:2020-11-01 00:00:00

  • Survival Benefit of Obese Patients With Pulmonary Embolism.

    abstract:OBJECTIVE:To investigate the impact of obesity and underweight on adverse in-hospital outcomes in pulmonary embolism (PE). PATIENTS AND METHODS:Patients diagnosed as having PE based on International Statistical Classification of Diseases and Related Health Problems, 10th Revision, German Modification code I26 in the G...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/j.mayocp.2019.04.035

    authors: Keller K,Hobohm L,Münzel T,Ostad MA,Espinola-Klein C,Lavie CJ,Konstantinides S,Lankeit M

    更新日期:2019-10-01 00:00:00

  • Cephalosporin antimicrobial agents and related compounds.

    abstract::Cephalosporins are broad-spectrum antimicrobial agents that are often used empirically to treat suspected bacterial infections and also to treat culture-proven infections due to selected gram-positive and gram-negative microorganisms. Cephalosporins differ widely in their spectrum of activity, susceptibility to beta-l...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审

    doi:10.1016/s0025-6196(12)61731-5

    authors: Gustaferro CA,Steckelberg JM

    更新日期:1991-10-01 00:00:00

  • Attitudes of Olmsted County, Minnesota, residents about tobacco smoke in restaurants and bars.

    abstract:OBJECTIVE:To determine the attitudes of Olmsted County, Minnesota, adults about environmental tobacco smoke in restaurants, bars, and nightclubs. SUBJECTS AND METHODS:In this population survey,2014 adults were contacted by random digit dial methods between February 28 and May 5, 2000, and asked to participate in a tel...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/S0025-6196(11)63118-2

    authors: Kottke TE,Aase LA,Brandel CL,Brekke MJ,Brekke LN,DeBoer SW,Hayes SN,Hoffman RS,Menzel PA,Thomas RJ

    更新日期:2001-02-01 00:00:00

  • Cyclosporine, low-density lipoprotein, and cholesterol.

    abstract::Lipoproteins are known to be able to transport a variety of drugs. This report suggests that low-density lipoprotein not only functions as an important carrier of cyclosporine in plasma but also facilitates transport of cyclosporine across the cell membrane by means of the low-density lipoprotein receptor. Such a mech...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/s0025-6196(12)64916-7

    authors: de Groen PC

    更新日期:1988-10-01 00:00:00

  • REM Sleep Behavior Disorder: Diagnosis, Clinical Implications, and Future Directions.

    abstract::Rapid eye movement sleep behavior disorder (RBD) is diagnosed by a clinical history of dream enactment accompanied by polysomnographic rapid eye movement sleep atonia loss (rapid eye movement sleep without atonia). Rapid eye movement sleep behavior disorder is strongly associated with neurodegenerative disease, especi...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审

    doi:10.1016/j.mayocp.2017.09.007

    authors: St Louis EK,Boeve BF

    更新日期:2017-11-01 00:00:00

  • Management of urinary retention: rapid versus gradual decompression and risk of complications.

    abstract::The literature was reviewed to quantify the risk of complications related to the relief of obstruction in urinary retention. We also sought to determine whether the risk of complications is higher with rapid or gradual decompression (or "clamping") of the obstructed urinary bladder. The medical literature was identifi...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审

    doi:10.1016/S0025-6196(11)63368-5

    authors: Nyman MA,Schwenk NM,Silverstein MD

    更新日期:1997-10-01 00:00:00

  • Use of Glucocorticoids and Risk of Community-Acquired Staphylococcus aureus Bacteremia: A Population-Based Case-Control Study.

    abstract:OBJECTIVE:To investigate whether the use of systemic glucocorticoids is a risk factor for community-acquired Staphylococcus aureus bacteremia (CA-SAB). PATIENTS AND METHODS:We used population-based medical registries in Northern Denmark to conduct a case-control study including all adults with first-time CA-SAB and ma...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/j.mayocp.2016.04.023

    authors: Smit J,Kaasch AJ,Søgaard M,Thomsen RW,Nielsen H,Frøslev T,Schønheyder HC

    更新日期:2016-07-01 00:00:00

  • Acute pancreatitis in the postpartum period: a population-based case-control study.

    abstract:OBJECTIVE:To determine relationships among pregnancy (during and postpartum), acute pancreatitis, and gallstones. PATIENTS AND METHODS:In this retrospective population-based case-control study, we identified all 12- to 50-year-old Rochester, Minn, females diagnosed between 1976 and 1991 as having acute pancreatitis (c...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.4065/75.4.361

    authors: Maringhini A,Lankisch MR,Zinsmeister AR,Melton LJ 3rd,DiMagno EP

    更新日期:2000-04-01 00:00:00

  • Measurement of trunk flexibility in normal subjects: reproducibility of three clinical methods.

    abstract::Although measurements of trunk flexibility are an important part of a clinical examination, subjective methods are usually used to assess spinal mobility. We studied three easily performed objective techniques for determining trunk flexibility (the common "fingertip-to-floor" test, the modified Schober and Moll tests,...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/s0025-6196(12)61848-5

    authors: Merritt JL,McLean TJ,Erickson RP,Offord KP

    更新日期:1986-03-01 00:00:00

  • Bypass surgery for vascular disease of the carotid system.

    abstract::A series of 58 operations on 56 patients, in whom a branch of the superficial temporal artery was anastomosed to a branch of the middle cerebral artery (STA-MCA bypass or Yasargil procedure), is reviewed. These operations were performed chiefly for occlussions or for inaccessible stenotic lesions of the internal carot...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:

    authors: Sundt TM Jr,Siekert RG,Piepgras DG,Sharbrough FW,Houser OW

    更新日期:1976-11-01 00:00:00

  • Psychogenic urinary retention in women.

    abstract::There appears to be a spectrum of psychogenic urinary retention that is seen mostly in women. The degrees of psychiatric disorder and bladder disorder do not necessarily coincide. Some patients with psychogenic retention may have one acute episode temporally related to psychologic trauma. Others may present with probl...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:

    authors: Barrett DM

    更新日期:1976-06-01 00:00:00

  • Dehydroepiandrosterone replacement therapy in hypoadrenal women: protein anabolism and skeletal muscle function.

    abstract:OBJECTIVE:To determine whether dehydroepiandrosterone (DHEA) replacement therapy in hypoadrenal women improves performance, muscle protein accretion, and mitochondrial functions. PARTICIPANTS AND METHODS:Thirty-three hypoadrenal women were enrolled in the study from May 1, 2002, through May 31, 2003. Twenty-eight comp...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,随机对照试验

    doi:10.4065/83.11.1218

    authors: Dhatariya KK,Greenlund LJ,Bigelow ML,Thapa P,Oberg AL,Ford GC,Schimke JM,Nair KS

    更新日期:2008-11-01 00:00:00

  • Horseshoe kidney associated with surgery of the abdominal aorta.

    abstract::Of 53 patients with horseshoe kidney (9 in the present series), 45 underwent operation for an abdominal aortic aneurysm: 40 electively and 5 on an emergency basis. The remaining eight patients underwent revascularization for arteriosclerosis obliterans. Of the 53 patients, 35 (66%) had renal artery anomalies. The anom...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:

    authors: Sidell PM,Pairolero PC,Payne WS,Bernatz PE,Spittel JA Jr

    更新日期:1979-02-01 00:00:00

  • Gestational diabetes mellitus: now is the time for detection and treatment.

    abstract::The extent of universal screening for gestational diabetes and the incidence of gestational diabetes mellitus (GDM) by diagnosis were analyzed in four primary-care sites. The medical records of 798 women were reviewed to identify the presence of historical risk factors, familial determinants, and biophysical attribute...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/s0025-6196(12)60932-x

    authors: Mazze RS,Krogh CL

    更新日期:1992-10-01 00:00:00

  • Epinephrine-induced QT interval prolongation: a gene-specific paradoxical response in congenital long QT syndrome.

    abstract:OBJECTIVE:To determine the effect of epinephrine on the QT interval in patients with genotyped long QT syndrome (LQTS). PATIENTS AND METHODS:Between May 1999 and April 2001, 37 patients (24 females) with genotyped LQTS (19 LQT1, 15 LQT2, 3 LQT3, mean age, 27 years; range, 10-53 years) from 21 different kindreds and 27...

    journal_title:Mayo Clinic proceedings

    pub_type: 临床试验,杂志文章

    doi:10.4065/77.5.413

    authors: Ackerman MJ,Khositseth A,Tester DJ,Hejlik JB,Shen WK,Porter CB

    更新日期:2002-05-01 00:00:00

  • Clinical value of the bile acid breath test. Evaluation of the Mayo Clinic experience.

    abstract::The Mayo Clinic experience with more than 200 bile acid breath tests was analyzed retrospectively to assess its clinical value. In patients with suspected bacterial overgrowth, the result of the bile acid breath test was compared with that of culture of aspirates of small bowel, and the test was found to have a sensit...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:

    authors: Lauterburg BH,Newcomer AD,Hofmann AF

    更新日期:1978-04-01 00:00:00

  • Epidemiological profile of Marfan syndrome in a general population: a national database study.

    abstract:OBJECTIVE:To explore the current epidemiological profile of Marfan syndrome in a general population. PATIENTS AND METHODS:Patients who had received a diagnosis of Marfan syndrome were identified from the Taiwan National Health Insurance database records from January 1, 2000, through December 31, 2012 (average populati...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/j.mayocp.2013.08.022

    authors: Chiu HH,Wu MH,Chen HC,Kao FY,Huang SK

    更新日期:2014-01-01 00:00:00

  • Associations of preexisting depression and anxiety with hospitalization in patients with cardiovascular disease.

    abstract:OBJECTIVE:To determine the risk of hospitalization and death in relation to preexisting depression and anxiety among patients with cardiovascular disease (CVD). PATIENTS AND METHODS:The cohort consisted of 799 Olmsted County, MN, residents diagnosed with CVD (myocardial infarction or heart failure) from January 1, 197...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.4065/mcp.2011.0148

    authors: Chamberlain AM,Vickers KS,Colligan RC,Weston SA,Rummans TA,Roger VL

    更新日期:2011-11-01 00:00:00

  • Use of Echocardiography in Olmsted County Outpatients With Chest Pain and Normal Resting Electrocardiograms Seen at Mayo Clinic Rochester.

    abstract:OBJECTIVE:To determine how often unnecessary resting echocardiograms that are "not recommended" by clinical practice guidelines are performed in patients with stable chest pain and normal resting electrocardiograms (ECGs). PATIENTS AND METHODS:We performed a retrospective search of electronic medical records of all ou...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/j.mayocp.2015.07.025

    authors: Gibbons RJ,Carryer D,Liu H,Brady PA,Askew JW,Hodge D,Ammash N,Ebbert JO,Roger VL

    更新日期:2015-11-01 00:00:00

  • Neurovascular microsurgery: a model for laboratory investigation and the development of technical skills.

    abstract::An inexpensive and reproducible model to help in developing the technical skills for, and to investigate experimentally, a microvascular anastomosis resembling the superficial temporal-middle cerebral artery bypass is described. The model is used to illustrate the important principles of microvascular surgery. Using a...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:

    authors: Rosenbaum TJ,Sundt TM Jr

    更新日期:1976-05-01 00:00:00

  • Use of intranasal cromolyn sodium for allergic rhinitis.

    abstract::Allergic rhinitis affects 10% to 20% of Americans. It frequently coexists with other conditions, such as allergic conjunctivitis, sinusitis, and asthma, and is associated with impaired occupational function and performance in school, decreased quality of life, and increased health care costs. An efficacious agent with...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审

    doi:10.4065/77.4.350

    authors: Ratner PH,Ehrlich PM,Fineman SM,Meltzer EO,Skoner DP

    更新日期:2002-04-01 00:00:00

  • Age-Related 2-Year Mortality After Transcatheter Aortic Valve Replacement: the YOUNG TAVR Registry.

    abstract:OBJECTIVE:To comparatively assess the natural history of patients of different ages undergoing transcatheter aortic valve replacement (TAVR). PATIENTS AND METHODS:For this study, we used the YOUNG TAVR, an international, multicenter registry investigating mortality trends up to 2 years in patients with aortic valve st...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.mayocp.2019.01.008

    authors: Navarese EP,Andreotti F,Kołodziejczak M,Wanha W,Lauten A,Veulemans V,Frediani L,Kubica J,de Cillis E,Wojakowski W,Ochala A,Zeus T,Bortone A,Buffon A,Jung C,Pestrichella V,Gurbel PA

    更新日期:2019-08-01 00:00:00

  • Performance of risk indices for identifying low bone density in postmenopausal women.

    abstract:OBJECTIVE:To examine the ability of 4 published osteoporosis risk indices to identify women with low bone density. SUBJECTS AND METHODS:Subjects included postmenopausal women 45 years and older consecutively recruited from US clinics, women from general practice centers in The Netherlands (age range, 50-80 years), wom...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.4065/77.7.629

    authors: Geusens P,Hochberg MC,van der Voort DJ,Pols H,van der Klift M,Siris E,Melton ME,Turpin J,Byrnes C,Ross P

    更新日期:2002-07-01 00:00:00