Epinephrine-induced QT interval prolongation: a gene-specific paradoxical response in congenital long QT syndrome.

abstract：:In this study, our aim was to test the hypothesis that colonic tone is abnormal in patients with irritable bowel syndrome (IBS). We studied eight patients with IBS and eight age-matched asymptomatic control subjects, in whom tone and motility were measured by an electronic barostat and by pneumohydraulic perfusion man...

journal_title：Mayo Clinic proceedings

authors： Vassallo MJ,Camilleri M,Phillips SF,Steadman CJ,Talley NJ,Hanson RB,Haddad AC

更新日期：1992-08-01 00:00:00

abstract：:We conducted a prospective, randomized trial to study the efficacy and tolerance of long-term versus short-term treatment with recombinant interferon alfa-2a in patients with chronic hepatitis B. Ten patients were randomly assigned to a 6-month interferon regimen, and 10 patients were assigned to a 3-week interferon t...

journal_title：Mayo Clinic proceedings

authors： Rakela J,Wood JR,Czaja AJ,O'Brien PC,Taswell HF,Bowyer BA,Lange SM,Anderson ML,Parent K

更新日期：1990-10-01 00:00:00

abstract：:The first 100 liver transplantations at the Mayo Clinic were performed in 83 patients, who required a total of 917 patient days in the intensive-care unit (ICU). The mean duration of stay in the ICU was 5.91 days after liver transplantation and 6.15 days for patients who subsequently required readmission to the ICU. D...

journal_title：Mayo Clinic proceedings

authors： Plevak DJ,Southorn PA,Narr BJ,Peters SG

更新日期：1989-04-01 00:00:00

abstract：:Autonomic failure and proximal skeletal myopathy are rare features of the Sjögren syndrome (SS). We describe a 51-year-old woman with primary SS who had development of esophageal dysmotility, urinary retention, severe orthostatism, and skeletal myopathy during a 3-month period after the diagnosis of SS. Her symptoms a...

journal_title：Mayo Clinic proceedings

authors： Sorajja P,Poirier MK,Bundrick JB,Matteson EL

更新日期：1999-07-01 00:00:00

abstract：OBJECTIVE:To report the clinicopathologic findings in patients with Grover's disease. MATERIAL AND METHODS:We reviewed the medical records and biopsy specimens from 72 patients with transient acantholytic dermatosis (Grover's disease) examined at Mayo Clinic Rochester. Hematoxylin-eosin-stained biopsy specimens (from ...

journal_title：Mayo Clinic proceedings

authors： Davis MD,Dinneen AM,Landa N,Gibson LE

更新日期：1999-03-01 00:00:00

abstract：OBJECTIVE:To study the incidence and prevalence of diagnosed myoclonus in Olmsted County, Minnesota. Little is known about the frequency and distribution of myoclonus in the general population. DESIGN:Descriptive study with case ascertainment through a records-linkage system. PATIENTS AND METHODS:We used a medical re...

journal_title：Mayo Clinic proceedings

authors： Caviness JN,Alving LI,Maraganore DM,Black RA,McDonnell SK,Rocca WA

更新日期：1999-06-01 00:00:00

abstract：:Giant cell myocarditis (GCM) is a rare and frequently fatal disorder with no proven treatment. Case reports and data from a rat model of GCM suggest that immunosuppressive therapy directed against T lymphocytes may have clinical benefit. We describe a 47-year-old man with severe acute heart failure due to GCM in whom ...

journal_title：Mayo Clinic proceedings

authors： Menghini VV,Savcenko V,Olson LJ,Tazelaar HD,Dec GW,Kao A,Cooper LT Jr

更新日期：1999-12-01 00:00:00

abstract：:To identify the wishes of patients with amyotrophic lateral sclerosis (ALS) for information, participation in decision making, and life-sustaining therapy and to determine whether these wishes are stable over time, we conducted a prospective survey (baseline and 6-month follow-up interviews) of 38 consecutive patients...

journal_title：Mayo Clinic proceedings

authors： Silverstein MD,Stocking CB,Antel JP,Beckwith J,Roos RP,Siegler M

更新日期：1991-09-01 00:00:00

abstract：:Graves disease is an autoimmune thyroid condition characterized by the production of autoantibodies against the thyrotropin receptor. The autoantibodies mimic the effect of the hormone on thyroid cells, which stimulates autonomous production of thyroxine and triiodothyronine. It has been hypothesized that cross-reacti...

journal_title：Mayo Clinic proceedings

authors： Budavari AI,Whitaker MD,Helmers RA

更新日期：2002-05-01 00:00:00

abstract：:Primary sclerosing cholangitis (PSC) predisposes to the development of cholangiocarcinoma, a usually fatal complication that is difficult to diagnose. Serum concentrations of CA 19-9, a tumor-associated antigen, are frequently increased in patients with only cholangiocarcinoma. The aim of this study was to assess the ...

journal_title：Mayo Clinic proceedings

authors： Nichols JC,Gores GJ,LaRusso NF,Wiesner RH,Nagorney DM,Ritts RE Jr

更新日期：1993-09-01 00:00:00

abstract：:Psychosocial and spiritual factors influence a broad spectrum of medical and surgical disorders. The adverse effects of stress have been most clearly documented in cardiovascular disease. In cancer, unresolved questions include the following: Do emotional factors have a causal role in either initiating or promoting a ...

journal_title：Mayo Clinic proceedings

authors： Creagan ET

更新日期：1997-02-01 00:00:00

abstract：:The extent of universal screening for gestational diabetes and the incidence of gestational diabetes mellitus (GDM) by diagnosis were analyzed in four primary-care sites. The medical records of 798 women were reviewed to identify the presence of historical risk factors, familial determinants, and biophysical attribute...

journal_title：Mayo Clinic proceedings

authors： Mazze RS,Krogh CL

更新日期：1992-10-01 00:00:00

abstract：:We developed and validated a radioimmunoassay for circulating human parathyroid hormone-related peptide (PTHrP), based on a commercial antiserum to the synthetic 1-34 fragment of PTHrP, 125I-Tyr degrees-PTHrP(1-34) as radioligand, and prior extraction of the native peptide from plasma with C-2 cartridges. We determine...

journal_title：Mayo Clinic proceedings

authors： Kao PC,Klee GG,Taylor RL,Heath H 3rd

更新日期：1990-11-01 00:00:00

abstract：OBJECTIVE:To determine whether sirolimus therapy is associated with neurologic complications, including stroke, among heart transplant recipients. PATIENTS AND METHODS:We retrospectively studied patients who underwent heart transplant at Mayo Clinic's site in Rochester, MN, from January 1, 1988, through June 30, 2006....

journal_title：Mayo Clinic proceedings

authors： van de Beek D,Kremers WK,Kushwaha SS,McGregor CG,Wijdicks EF

更新日期：2009-04-01 00:00:00

abstract：:Penile squamous cell carcinoma (PSCC) is a rare cancer, with approximately 2000 new cases in the United States and 35,000 globally every year. Multiple risk factors are involved in PSCC, but most importantly, the high-risk human papillomavirus infection is thought to be present in approximately 50% of cases. Penile sq...

journal_title：Mayo Clinic proceedings

authors： Chahoud J,Kohli M,Spiess PE

更新日期：2020-12-08 00:00:00

abstract：OBJECTIVE:To examine the effect of objectively measured exercise capacity (EC) on early mortality (EM) after a first myocardial infarction (MI). PATIENTS AND METHODS:This retrospective cohort study included 2061 patients without a history of MI (mean age, 62±12 years; 38% [n=790] women; 56% [n=1153] white) who underwe...

journal_title：Mayo Clinic proceedings

authors： Shaya GE,Al-Mallah MH,Hung RK,Nasir K,Blumenthal RS,Ehrman JK,Keteyian SJ,Brawner CA,Qureshi WT,Blaha MJ

更新日期：2016-02-01 00:00:00

abstract：:Seven vertex-positive potentials--the brainstem auditory response--can be recorded from the human scalp within 10 milliseconds of an appropriate acoustic stimulus. The first of these potentials is generated in the acoustic nerve, the third in the pons, and the fifth in the midbrain. Measurement of the relative latenci...

journal_title：Mayo Clinic proceedings

authors： Stockard JJ,Stockard JE,Sharbrough FW

更新日期：1977-12-01 00:00:00

abstract：:Clinical guidelines for instituting pharmacotherapy for the primary prevention of atherosclerotic cardiovascular disease (ASCVD), specifically lipid management and aspirin, have long been based on absolute risk. However, lipid management in the current era remains challenging to both patients and clinicians in the set...

journal_title：Mayo Clinic proceedings

authors： Michos ED,Blaha MJ,Blumenthal RS

更新日期：2017-12-01 00:00:00

abstract：:Patients with ectatic coronary arteries often have occlusion of the affected arteries. Because ectatic arteries are considered to have medial damage, they are normally assumed to have little capacity to constrict; therefore, spasm has not been considered a factor in the occlusive process. In two patients who had diffu...

journal_title：Mayo Clinic proceedings

authors： Bove AA,Vlietstra RE

更新日期：1985-12-01 00:00:00

abstract：OBJECTIVE:To assess long-term secular trends in the utilization of bilateral compared with unilateral orchiectomy in the community. PATIENTS AND METHODS:This population-based descriptive study reviewed medical records of all Olmsted County, Minnesota, men undergoing orchiectomy between 1956 and 2000. RESULTS:Over the...

journal_title：Mayo Clinic proceedings

authors： Melton LJ 3rd,Alothman KI,Achenbach SJ,O'Fallon WM,Zincke H

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVE:To ascertain the usefulness of bone marrow and cerebrospinal fluid (CSF) examinations in identifying or predicting relapse in children with acute lymphoblastic leukemia (ALL) before discontinuation of chemotherapy. MATERIAL AND METHODS:We retrospectively reviewed the medical records of 113 children with ALL ...

journal_title：Mayo Clinic proceedings

authors： Hutt PJ,Sabio H,Gilchrist GS,O'Brien C

更新日期：1996-09-01 00:00:00

abstract：OBJECTIVE:To examine current therapeutic modalities for acute lymphocytic leukemia (ALL) in adults, analyze prognostic variables, and offer treatment recommendations. DESIGN:We reviewed our experience with 90 adult patients with ALL examined at the Mayo Clinic between 1982 and 1992 and used it as a background for disc...

journal_title：Mayo Clinic proceedings

authors： Ho TC,Tefferi A,Su JQ,Litzow MR,Hoagland HC,Noël P

更新日期：1994-10-01 00:00:00

abstract：OBJECTIVE:To gain information regarding long-term follow-up in patients with synchronous bilateral solid renal neoplasms in whom renal-preserving surgery is imperative. PATIENTS AND METHODS:We examined our surgical experience and the survival outcome, as evaluated by Kaplan-Meier and log-rank analysis, of 94 patients ...

journal_title：Mayo Clinic proceedings

authors： Blute ML,Amling CL,Bryant SC,Zincke H

更新日期：2000-10-01 00:00:00

abstract：:The Human Genome Project has resulted in a new era in the field of pharmacogenetics in which researchers are rapidly discovering new genetic variation, which may help to explain interindividual variability in drug efficacy and toxicity. Pharmacogenetics is the study of the role of genetic inheritance in individual var...

journal_title：Mayo Clinic proceedings

authors： Goetz MP,Ames MM,Weinshilboum RM

更新日期：2004-03-01 00:00:00

abstract：:Thirty-one patients with low back pain resistant to medical and surgical treatment were studied. On admission to the psychiatric service, these patients revealed apparent features of conversion and hysterical personality, as characterized also by the MMPI profile. During hospitalization, however, there was increased a...

journal_title：Mayo Clinic proceedings

authors： Maruta T,Swanson DW,Swenson WM

更新日期：1976-01-01 00:00:00

abstract：:Giant cell arteritis and polymyalgia rheumatica were described separately more than 100 years ago. However, the original reports of both conditions were neglected for many years. After the article by Horton et al on giant cell arteritis in the 1930s and studies published by others in the 1940s, giant cell arteritis be...

journal_title：Mayo Clinic proceedings

authors： Hunder GG

更新日期：2006-08-01 00:00:00

abstract：:A 37-year-old man was referred to our institution for assessment of possible sarcoidosis with involvement of the central nervous system. Before referral, he experienced a systemic illness that persisted for several months, during which time ocular and pulmonary noncaseating granulomas were identified. Sarcoidosis with...

journal_title：Mayo Clinic proceedings

authors： Edmonds LC,Stubbs SE,Ryu JH

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:To report the third known and documented occurrence of malignant disease as a complication of immunosuppression associated with low-dose methotrexate therapy for rheumatoid arthritis. MATERIAL AND METHODS:We present a case report of a 64-year-old woman with rheumatoid arthritis who had received low-dose meth...

journal_title：Mayo Clinic proceedings

authors： Zimmer-Galler I,Lie JT

更新日期：1994-03-01 00:00:00

abstract：:Considerable morbidity and mortality are associated with infections of vascular prosthetic grafts. Most vascular surgeons believe that once vascular prosthetic graft infections occur, any form of therapy short of removal of the prosthesis will fail. Although recent reports have noted the successful conservative treatm...

journal_title：Mayo Clinic proceedings

authors： Knight CD Jr,Farnell MB,Hollier LH

更新日期：1983-07-01 00:00:00

abstract：:The monoclonal gammopathies are a group of disorders characterized by proliferation of a single clone of plasma cells that produce a homogeneous, monoclonal (M) protein. The structure of immunoglobulins, relationship of normal (polyclonal) immunoglobulins to myeloma and macroglobulin (monoclonal) immunoglobulins, patt...

journal_title：Mayo Clinic proceedings

authors： Kyle RA,Greipp PR

更新日期：1978-11-01 00:00:00