Abstract:
OBJECTIVE:To investigate the impact of obesity and underweight on adverse in-hospital outcomes in pulmonary embolism (PE). PATIENTS AND METHODS:Patients diagnosed as having PE based on International Statistical Classification of Diseases and Related Health Problems, 10th Revision, German Modification code I26 in the German nationwide inpatient database were stratified for obesity, underweight, and normal weight/overweight (reference group) and compared regarding adverse in-hospital outcomes. RESULTS:From January 1, 2011, through December 31, 2014, 345,831 inpatients (53.3% females) 18 years and older were included in this analysis; 8.6% were obese and 0.5% were underweight. Obese patients were younger (67.0 vs 73.0 years), were more frequently female (60.2% vs 52.7%), had a lower cancer rate (13.6% vs 20.5%), and were more often treated with systemic thrombolysis (6.4% vs 4.3%) and surgical embolectomy (0.3% vs 0.1%) vs the reference group (P<.001 for all). Overall, 51,226 patients (14.8%) died during in-hospital stay. Obese patients had lower mortality (10.9% vs 15.2%; P<.001) vs the reference group and a reduced odds ratio (OR) for in-hospital mortality (OR, 0.74; 95% CI, 0.71-0.77; P<.001) independent of age, sex, comorbidities, and reperfusion therapies. This survival benefit of obese patients was more pronounced in obesity classes I (OR, 0.56; 95% CI, 0.52-0.60; P<.001) and II (OR, 0.63; 95% CI 0.58-0.69; P<.001). Underweight patients had higher prevalence of cancer and higher mortality rates (OR, 1.15; 95% CI, 1.00-1.31; P=.04). CONCLUSION:Obesity is associated with decreased in-hospital mortality rates in patients with PE. Although obese patients were more often treated with reperfusion therapies, the survival benefit of obese patients occurred independently of age, sex, comorbidities, and reperfusion treatment.
journal_name
Mayo Clin Procjournal_title
Mayo Clinic proceedingsauthors
Keller K,Hobohm L,Münzel T,Ostad MA,Espinola-Klein C,Lavie CJ,Konstantinides S,Lankeit Mdoi
10.1016/j.mayocp.2019.04.035subject
Has Abstractpub_date
2019-10-01 00:00:00pages
1960-1973issue
10eissn
0025-6196issn
1942-5546pii
S0025-6196(19)30426-4journal_volume
94pub_type
杂志文章abstract:OBJECTIVE:To describe management of patients with permanent pacemaker (PPM)- and implantable cardioverter-defibrillator (ICD)-related endocarditis. PATIENTS AND METHODS:We retrospectively reviewed all cases of infection involving PPMs and ICDs among patients presenting to Mayo Clinic's site in Rochester, MN, between J...
journal_title:Mayo Clinic proceedings
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doi:10.4065/83.1.46
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abstract::Two entities of special interest in sleep disorders medicine are restless legs syndrome and periodic movements of sleep. Most patients with restless legs syndrome have periodic movements of sleep, but most patients with the nocturnal disorder do not have restless legs when awake. In both conditions, the underlying cau...
journal_title:Mayo Clinic proceedings
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pub_type: 杂志文章,评审
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更新日期:1984-08-01 00:00:00
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doi:10.1016/S0025-6196(11)61536-X
更新日期:2005-06-01 00:00:00
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journal_title:Mayo Clinic proceedings
pub_type: 杂志文章,评审
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更新日期:1990-02-01 00:00:00
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journal_title:Mayo Clinic proceedings
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doi:
更新日期:1982-11-01 00:00:00
abstract::Nasal telangiectasias, a common condition, can be caused by chronic exposure to ultraviolet light, rosacea, topically applied corticosteroids, or rhinoplasty. Use of the argon laser for 15 to 45 minutes in a continuous mode over the entire involved area can produce considerable lightening of the nasal redness and impr...
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更新日期:2015-09-01 00:00:00
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doi:
更新日期:1982-07-01 00:00:00
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doi:
更新日期:1983-04-01 00:00:00
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更新日期:2016-10-01 00:00:00