Antimicrobial photodynamic effect to treat residual pockets in periodontal patients: a randomized controlled clinical trial.

Abstract:

AIM:A randomized controlled clinical trial was designed to evaluate the efficacy of the photodynamic therapy (PDT) in the treatment of residual pockets of chronic periodontitis patients. MATERIAL AND METHODS:Thirty-four patients with at least four residual periodontal pockets undergoing maintenance care were included and randomly assigned to test group (PDT, n = 18) or control group (sham procedure, n = 16). The intervention was performed at baseline, 3, 6 and 12 months. Clinical parameters such as pocket probing depth (PPD), clinical attachment level (CAL), bleeding on probing (BoP) and plaque index (PI) were measured before intervention and after 3, 6 and 12 months. Subgingival samples were obtained at baseline, and after 7 days, 3, 6 and 12 months to quantify Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Treponema denticola and Tannerella forsythia by real-time polimerase chain reaction (PCR). RESULTS:All clinical variables showed significant improvement during the study, but there was no significant difference between test and control groups. The microbiological analyses showed no differences between groups at any time during the study. CONCLUSION:Within the limits of this clinical trial and considering the laser and photosensitizer protocol used, PDT failed to demonstrate additional clinical and bacteriological benefits in residual pockets treatment.

journal_name

J Clin Periodontol

authors

Carvalho VF,Andrade PV,Rodrigues MF,Hirata MH,Hirata RD,Pannuti CM,De Micheli G,Conde MC

doi

10.1111/jcpe.12393

subject

Has Abstract

pub_date

2015-05-01 00:00:00

pages

440-7

issue

5

eissn

0303-6979

issn

1600-051X

journal_volume

42

pub_type

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