Characterization of four new monoclonal antibodies against the distal N-terminal region of PrP(c).

abstract：:The capacity for aerial maneuvering was likely a major influence on the evolution of flying animals. Here we evaluate consequences of paravian morphology for aerial performance by quantifying static stability and control effectiveness of physical models for numerous taxa sampled from within the lineage leading to bird...

journal_title：PeerJ

authors： Evangelista D,Cam S,Huynh T,Kwong A,Mehrabani H,Tse K,Dudley R

更新日期：2014-10-16 00:00:00

abstract：:The most intense commercial harvest of marine aquarium species in North America occurs in the coastal waters surrounding Florida, yet very often little information exists on the life histories, population dynamics, or reproductive characteristics of these organisms. The peppermint shrimp Lysmata boggessi is one such s...

journal_title：PeerJ

authors： Dickson MD,Behringer DC,Baeza JA

更新日期：2020-01-23 00:00:00

abstract：:Paratya australiensis Kemp (Decapoda: Atyidae) is a widely distributed freshwater shrimp in eastern Australia. The species has been considered as an important stream organism for studying genetics, dispersal, biology, behaviour and evolution in atyids and is a major food source for stream dwelling fishes. Paratya aust...

journal_title：PeerJ

authors： Rahman S,Schmidt D,Hughes JM

更新日期：2020-01-09 00:00:00

abstract：:The present study evaluated the level of support and satisfaction among parents of stillborn babies in Australian hospitals. One-hundred and eighty-nine mothers and fathers completed an online survey designed by the researcher based on the guidelines designed by the Perinatal Society of Australia and New Zealand. Supp...

journal_title：PeerJ

authors： Basile ML,Thorsteinsson EB

更新日期：2015-06-25 00:00:00

abstract：:Melanoma is a global concern and accounts for the major mortality of skin cancers. Herpes simplex virus thymidine kinase gene with ganciclovir (HSV-TK/GCV) is a promising gene therapy for melanoma. Despite its low efficiency, it is well known for its bystander effect which is mainly mediated by gap junction. In this s...

journal_title：PeerJ

authors： Li H,Du H,Zhang G,Wu Y,Qiu P,Liu J,Guo J,Liu X,Sun L,Du B,Tan Y

更新日期：2019-09-20 00:00:00

abstract：:Background. Just as for most other tortoise species, the once common Chaco tortoise, Chelonoidis chilensis (Testudinidae), is under constant threat across it distribution in Argentina, Bolivia and Paraguay. Despite initial qualitative description of the species distribution and further individual reports of new locati...

journal_title：PeerJ

authors： Ruete A,Leynaud GC

更新日期：2015-10-01 00:00:00

abstract：Background:Much of the shape variation found in animals is based on allometry and heterochrony. Horses represent an excellent model to investigate patterns of size-shape variation among breeds that were intentionally bred for extreme small and large sizes. Methods:We tested whether ponies (wither height < 148 cm) have...

journal_title：PeerJ

authors： Heck L,Sanchez-Villagra MR,Stange M

更新日期：2019-09-16 00:00:00

abstract：:The incidence of pediatric cancer is lower than that of adult cancer worldwide. However, the former has detrimental side effects on the health of individuals, even after the cancer is cured, due to the impact of treatment on development. Recently, correlations have been made between the gut microbiome and cancer in se...

journal_title：PeerJ

authors： Sahly N,Moustafa A,Zaghloul M,Salem TZ

更新日期：2019-09-23 00:00:00

abstract：Background:Cholera, an acute enteric infection, is a serious health challenge in both the underdeveloped and the developing world. It is caused by Vibrio cholerae after ingestion of fecal contaminated food or water. Cholera outbreaks have recently been observed in regions facing natural calamities (i.e., earthquake in ...

journal_title：PeerJ

authors： Rashid MI,Rehman S,Ali A,Andleeb S

更新日期：2019-06-19 00:00:00

abstract：OBJECTIVES:The purpose of this study is to determine the prevalence and clinical impact of human papillomavirus (HPV) related laryngeal squamous cell carcinoma (LSCC). METHODS:A total of 106 LSCC patients who underwent primary surgical resection with or without adjuvant radiotherapy/chemoradiotherapy were enrolled ret...

journal_title：PeerJ

authors： Chen WC,Chuang HC,Lin YT,Huang CC,Chien CY

更新日期：2017-05-30 00:00:00

abstract：:Natural and anthropogenic changes (e.g., land use change, pollution) will alter many environmental factors in the coming years, including the amount of solar radiation reaching the earth's surface. Alterations in solar radiation exposure is likely to impact the ecologies of many living organisms, including invertebrat...

journal_title：PeerJ

authors： Villena OC,Momen B,Sullivan J,Leisnham PT

更新日期：2018-12-18 00:00:00

abstract：:Multidrug and toxic compound extrusion (MATE) transporters contribute to multidrug resistance and play major determinants of aluminum (Al) tolerance in plants. Alfalfa (Medicago sativa L.) is the most extensively cultivated forage crop in the world, yet most alfalfa cultivars are not Al tolerant. The basic knowledge o...

journal_title：PeerJ

authors： Min X,Jin X,Liu W,Wei X,Zhang Z,Ndayambaza B,Wang Y

更新日期：2019-01-31 00:00:00

abstract：:It is deemed important to understand cetacean occurrence and distribution to comprehend their ecological roles. The geographical occurrence of species' niche can be used to better describe their potential distribution. The niche can be defined using environmental variables. Those variables are considered static and no...

journal_title：PeerJ

authors： Figueiredo GCE,do Amaral KB,Santos MCO

更新日期：2020-10-05 00:00:00

abstract：:The Yazoo Darter, Etheostoma raneyi (Percidae), is an imperiled freshwater fish species endemic to tributaries of the Yocona and Little Tallahatchie rivers of the upper Yazoo River basin, in northern Mississippi, USA. The two populations are allopatric, isolated by unsuitable lowland habitat between the two river drai...

journal_title：PeerJ

authors： Sterling KA,Nielsen SV,Brown AJ,Warren ML Jr,Noonan BP

更新日期：2020-05-04 00:00:00

abstract：:The rapidly changing climate makes humans realize that there is a critical need to incorporate climate change adaptation into conservation planning. Whether the wintering habitats of Great Bustards (Otis tarda dybowskii), a globally endangered migratory subspecies whose population is approximately 1,500-2,200 individu...

journal_title：PeerJ

authors： Mi C,Falk H,Guo Y

更新日期：2016-02-01 00:00:00

abstract：Background:Variation in management across elephant camps likely has differential effects on the well-being of elephants. Methods:This study calculated body condition, foot health and skin wound scores (WSs) for 122 elephants from 15 elephant camps in Chiang Mai province, and examined relationships to management factor...

journal_title：PeerJ

authors： Bansiddhi P,Nganvongpanit K,Brown JL,Punyapornwithaya V,Pongsopawijit P,Thitaram C

更新日期：2019-04-25 00:00:00

abstract：:Prostaglandin E1 (PGE1), known pharmaceutically as alprostadil, has vasodilatory properties and is used widely in various clinical settings. In addition to acute vasodilatory properties, PGE1 may exert beneficial effects by altering protein expression of vascular cells. PGE1 is reported to be a potent stimulator of an...

journal_title：PeerJ

authors： Suzuki K,Nishi K,Takabuchi S,Kai S,Matsuyama T,Kurosawa S,Adachi T,Maruyama T,Fukuda K,Hirota K

更新日期：2013-11-28 00:00:00

abstract：Background:Lumbar spinal stenosis (LSS) is a common cause of low back pain with degenerative spinal change in older adults. Telomeres are repetitive nucleoprotein DNA sequences of TTAGGG at the ends of chromosomes. Oxidative stress originates from an imbalance in pro-oxidant and antioxidant homeostasis that results in ...

journal_title：PeerJ

authors： Dechsupa S,Yingsakmongkol W,Limthongkul W,Singhatanadgige W,Honsawek S

更新日期：2018-08-09 00:00:00

abstract：:Advances in sequencing techniques have led to exponential growth in biological data, demanding the development of large-scale bioinformatics experiments. Because these experiments are computation- and data-intensive, they require high-performance computing techniques and can benefit from specialized technologies such ...

journal_title：PeerJ

authors： Mondelli ML,Magalhães T,Loss G,Wilde M,Foster I,Mattoso M,Katz D,Barbosa H,de Vasconcelos ATR,Ocaña K,Gadelha LMR Jr

更新日期：2018-08-29 00:00:00

abstract：:As a vector of Xylella fastidiosa (Wells, 1987) in Europe, the meadow spittlebug Philaenus spumarius (Linnaeus, 1758) (Hemiptera, Aphrophoridae) is a species of major concern. Therefore, tools and agents to control this ubiquitous insect that develops and feeds on hundreds of plant species are wanted. We conducted a f...

journal_title：PeerJ

authors： Mesmin X,Chartois M,Genson G,Rossi JP,Cruaud A,Rasplus JY

更新日期：2020-03-24 00:00:00

abstract：Background:Oral cancer progresses from hyperplastic epithelial lesions through dysplasia to invasive carcinoma. The critical needs in oral cancer treatment are expanding our knowledge of malignant tumour progression and the development of useful approaches to prevent dysplastic lesions. This study was designed to gain ...

journal_title：PeerJ

authors： Ge S,Zhou H,Zhou Z,Liu L,Lou J

更新日期：2021-01-04 00:00:00

abstract：:Aedes aegypti is the major vector of dengue, yellow fever and chikungunya viruses that put millions of people in endemic countries at risk. Mass rearing of this mosquito is crucial for strategies that use modified insects to reduce vector populations and transmission of pathogens, such as sterile insect technique or p...

journal_title：PeerJ

authors： Gonzales KK,Tsujimoto H,Hansen IA

更新日期：2015-05-05 00:00:00

abstract：:Background. Neonatal hyperbilirubinemia (HB) may cause severe neurological damage, but serious consequences are effectively controlled by phototherapy and blood exchange transfusion. HB is still a serious health problem in economically compromised parts of the world. The long term outcome has been regarded favorable b...

journal_title：PeerJ

authors： Hokkanen L,Launes J,Michelsson K

更新日期：2014-03-04 00:00:00

abstract：:A cervical vertebra of the large, pelagic pterodactyloid pterosaur Pteranodon sp. from the Late Cretaceous Niobrara Formation of Kansas, USA is significant for its association with a tooth from the large lamniform shark, Cretoxyrhina mantelli. Though the tooth does not pierce the vertebral periosteum, the intimate ass...

journal_title：PeerJ

authors： Hone DWE,Witton MP,Habib MB

更新日期：2018-12-14 00:00:00

abstract：:Ceratopsids ("horned dinosaurs") are known from western North America and Asia, a distribution reflecting an inferred subaerial link between the two landmasses during the Late Cretaceous. However, this clade was previously unknown from eastern North America, presumably due to limited outcrop of the appropriate age and...

journal_title：PeerJ

authors： Farke AA,Phillips GE

更新日期：2017-05-23 00:00:00

abstract：:Circular rep-encoding ssDNA (CRESS-DNA) viruses are common constituents of invertebrate viral consortia. Despite their ubiquity and sequence diversity, the effects of CRESS-DNA viruses on invertebrate biology and ecology remain largely unknown. This study assessed the relationship between the transcriptional profile o...

journal_title：PeerJ

authors： Bistolas KSI,Rudstam LG,Hewson I

更新日期：2017-09-26 00:00:00

abstract：:Agriculture is one of the main drivers of land conversion, and agriculture practices can impact on microbial diversity. Here we characterized the phyllosphere fungal diversity associated with Carménère grapevines under conventional and organic agricultural management. We also explored the fungal diversity present in t...

journal_title：PeerJ

authors： Castañeda LE,Miura T,Sánchez R,Barbosa O

更新日期：2018-10-29 00:00:00

abstract：Background:Several heart malformations are associated with mutations in the regulatory regions of cardiac genes. Troponin I type 1b (tnni1b) is important for the formation of the atrioventricular canal in zebrafish hearts; however, the regulation of tnni1b is poorly understand. We aimed to identify a small but function...

journal_title：PeerJ

authors： Zhang Y,Wang F,Wu F,Wang Y,Wang X,Gui Y,Li Q

更新日期：2020-11-04 00:00:00

abstract：:Recently, herbal drugs and their bioactive compounds have gained popularity in the management of diabetes mellitus (DM), which has become an epidemic disease all over the world and is especially prevalent in the Kingdom of Saudi Arabia (KSA). This study aimed to investigate the antidiabetic effect of ethanolic and aqu...

journal_title：PeerJ

authors： Gad-Elkareem MAM,Abdelgadir EH,Badawy OM,Kadri A

更新日期：2019-02-18 00:00:00

abstract：:Management of low-mobility or benthic fisheries is a difficult task because variation in the spatial distribution and population dynamics of the resources make the monitoring and assessment of these fisheries challenging. We assumed that environmental, spatial, and temporal factors can contribute to the variability of...

journal_title：PeerJ

authors： Murillo-Posada JC,Salas S,Velázquez-Abunader I

更新日期：2019-07-08 00:00:00