Protease-degradable electrospun fibrous hydrogels.

abstract：:Macrophages are a major immune cell type infiltrating tumors and promoting tumor growth and metastasis. To elucidate the mechanism of macrophage recruitment, we utilize an overgrowth tumor model ("undead" model) in larval Drosophila imaginal discs that are attached by numerous macrophages. Here we report that changes ...

journal_title：Nature communications

authors： Diwanji N,Bergmann A

更新日期：2020-07-20 00:00:00

abstract：:The concept of spin-torque-driven high-frequency magnetization dynamics, allows the potential construction of complex networks of non-linear dynamical nanoscale systems, combining the field of spintronics and the study of non-linear systems. In the few previous demonstrations of synchronization of several spin-torque ...

journal_title：Nature communications

authors： Lebrun R,Tsunegi S,Bortolotti P,Kubota H,Jenkins AS,Romera M,Yakushiji K,Fukushima A,Grollier J,Yuasa S,Cros V

更新日期：2017-06-12 00:00:00

abstract：:The extent to which the impact of regulatory genetic variants may depend on other factors, such as the expression levels of upstream transcription factors, remains poorly understood. Here we report a framework in which regulatory variants are first aggregated into sets, and using these as estimates of the total cis-ge...

journal_title：Nature communications

authors： Wragg D,Liu Q,Lin Z,Riggio V,Pugh CA,Beveridge AJ,Brown H,Hume DA,Harris SE,Deary IJ,Tenesa A,Prendergast JGD

更新日期：2020-01-17 00:00:00

abstract：:Single-nucleotide substitutions are a defining characteristic of cancer genomes. Many single-nucleotide substitutions in cancer genomes arise because of errors in DNA replication, which is spatio-temporally stratified. Here we propose that DNA replication patterns help shape the mutational landscapes of normal and can...

journal_title：Nature communications

authors： Liu L,De S,Michor F

更新日期：2013-01-01 00:00:00

abstract：:Blood vessels in the central nervous system (CNS) develop unique features, but the contribution of CNS neurons to regulating those features is not fully understood. We report that inhibiting spontaneous cholinergic activity or reducing starburst amacrine cell numbers prevents invasion of endothelial cells into the dee...

journal_title：Nature communications

authors： Weiner GA,Shah SH,Angelopoulos CM,Bartakova AB,Pulido RS,Murphy A,Nudleman E,Daneman R,Goldberg JL

更新日期：2019-06-06 00:00:00

abstract：:The Lyme disease agent, Borrelia burgdorferi, colonizes the gut of the tick Ixodes scapularis, which transmits the pathogen to vertebrate hosts including humans. Here we show that B. burgdorferi colonization increases the expression of several tick gut genes including pixr, encoding a secreted gut protein with a Reele...

journal_title：Nature communications

authors： Narasimhan S,Schuijt TJ,Abraham NM,Rajeevan N,Coumou J,Graham M,Robson A,Wu MJ,Daffre S,Hovius JW,Fikrig E

更新日期：2017-08-04 00:00:00

abstract：:Stackable select devices such as the oxide p-n junction diode and the Schottky diode (one-way switch) have been proposed for non-volatile unipolar resistive switching devices; however, bidirectional select devices (or two-way switch) need to be developed for bipolar resistive switching devices. Here we report on a ful...

journal_title：Nature communications

authors： Lee MJ,Lee D,Cho SH,Hur JH,Lee SM,Seo DH,Kim DS,Yang MS,Lee S,Hwang E,Uddin MR,Kim H,Chung UI,Park Y,Yoo IK

更新日期：2013-01-01 00:00:00

abstract：:Dendrimers are well-defined macromolecules whose highly branched structure is reminiscent of many natural structures, such as trees, dendritic cells, neurons or the networks of kidneys and lungs. Nature has privileged such branched structures for increasing the efficiency of exchanges with the external medium; thus, t...

journal_title：Nature communications

authors： Caminade AM,Fruchon S,Turrin CO,Poupot M,Ouali A,Maraval A,Garzoni M,Maly M,Furer V,Kovalenko V,Majoral JP,Pavan GM,Poupot R

更新日期：2015-07-14 00:00:00

abstract：:Synapse formation is triggered through trans-synaptic interaction between pairs of pre- and postsynaptic adhesion molecules, the specificity of which depends on splice inserts known as 'splice-insert signaling codes'. Receptor protein tyrosine phosphatase δ (PTPδ) can bidirectionally induce pre- and postsynaptic diffe...

journal_title：Nature communications

authors： Yamagata A,Yoshida T,Sato Y,Goto-Ito S,Uemura T,Maeda A,Shiroshima T,Iwasawa-Okamoto S,Mori H,Mishina M,Fukai S

更新日期：2015-04-24 00:00:00

abstract：:Electric gating can strongly modulate a wide variety of physical properties in semiconductors and insulators, such as significant changes of conductivity in silicon, appearance of superconductivity in SrTiO3, the paramagnet-ferromagnet transition in (In,Mn)As, and so on. The key to such modulation is charge accumulati...

journal_title：Nature communications

authors： Dushenko S,Hokazono M,Nakamura K,Ando Y,Shinjo T,Shiraishi M

更新日期：2018-08-07 00:00:00

abstract：:Nontyphoidal Salmonella (NTS) is a major cause of bacteraemia in Africa. The disease typically affects HIV-infected individuals and young children, causing substantial morbidity and mortality. Here we present a genome-wide association study (180 cases, 2677 controls) and replication analysis of NTS bacteraemia in Keny...

journal_title：Nature communications

authors： Gilchrist JJ,Rautanen A,Fairfax BP,Mills TC,Naranbhai V,Trochet H,Pirinen M,Muthumbi E,Mwarumba S,Njuguna P,Mturi N,Msefula CL,Gondwe EN,MacLennan JM,Chapman SJ,Molyneux ME,Knight JC,Spencer CCA,Williams TN,MacLenna

更新日期：2018-03-09 00:00:00

abstract：:Magnetic reconnection (MR) is a fundamental plasma process associated with conversion of the magnetic field energy into kinetic plasma energy, which is invoked to explain many non-thermal signatures in astrophysical events. Here we demonstrate that ultrafast relativistic MR in a magnetically dominated regime can be tr...

journal_title：Nature communications

authors： Yi L,Shen B,Pukhov A,Fülöp T

更新日期：2018-04-23 00:00:00

abstract：:Cytochrome P450 monooxygenases are versatile heme-thiolate enzymes that catalyze a wide range of reactions. Self-sufficient cytochrome P450 enzymes contain the redox partners in a single polypeptide chain. Here, we present the crystal structure of full-length CYP116B46, a self-sufficient P450. The continuous polypepti...

journal_title：Nature communications

authors： Zhang L,Xie Z,Liu Z,Zhou S,Ma L,Liu W,Huang JW,Ko TP,Li X,Hu Y,Min J,Yu X,Guo RT,Chen CC

更新日期：2020-05-29 00:00:00

abstract：:As academic careers become more competitive, junior scientists need to understand the value that mentorship brings to their success in academia. Previous research has found that, unsurprisingly, successful mentors tend to train successful students. But what characteristics of this relationship predict success, and how...

journal_title：Nature communications

authors： Liénard JF,Achakulvisut T,Acuna DE,David SV

更新日期：2018-11-27 00:00:00

abstract：:The development of single molecule white light emitters is extremely challenging for pure phosphorescent metal-free system at room temperature. Here we report a single pure organic phosphor, namely 4-chlorobenzoyldibenzothiophene, emitting white room temperature phosphorescence with Commission Internationale de l'Écla...

journal_title：Nature communications

authors： He Z,Zhao W,Lam JWY,Peng Q,Ma H,Liang G,Shuai Z,Tang BZ

更新日期：2017-09-04 00:00:00

abstract：:The dynamics of many natural and artificial systems are well described as random walks on a network: the stochastic behaviour of molecules, traffic patterns on the internet, fluctuations in stock prices and so on. The vast literature on random walks provides many tools for computing properties such as steady-state pro...

journal_title：Nature communications

authors： Perkins TJ,Foxall E,Glass L,Edwards R

更新日期：2014-10-14 00:00:00

abstract：:DNA-based nanopores are synthetic biomolecular membrane pores, whose geometry and chemical functionality can be tuned using the tools of DNA nanotechnology, making them promising molecular devices for applications in single-molecule biosensing and synthetic biology. Here we introduce a large DNA membrane channel with ...

journal_title：Nature communications

authors： Krishnan S,Ziegler D,Arnaut V,Martin TG,Kapsner K,Henneberg K,Bausch AR,Dietz H,Simmel FC

更新日期：2016-09-23 00:00:00

abstract：:The core of a ferromagnetic vortex domain creates a strong, localized magnetic field, which can be manipulated on nanosecond timescales, providing a platform for addressing and controlling individual nitrogen-vacancy centre spins in diamond at room temperature, with nanometre-scale resolution. Here, we show that the f...

journal_title：Nature communications

authors： Wolf MS,Badea R,Berezovsky J

更新日期：2016-06-14 00:00:00

abstract：:Human pre-implantation embryonic development involves extensive changes in chromatin structure and transcriptional activity. Here, we report on LiCAT-seq, a technique that enables simultaneous profiling of chromatin accessibility and gene expression with ultra-low input of cells, and map the chromatin accessibility an...

journal_title：Nature communications

authors： Liu L,Leng L,Liu C,Lu C,Yuan Y,Wu L,Gong F,Zhang S,Wei X,Wang M,Zhao L,Hu L,Wang J,Yang H,Zhu S,Chen F,Lu G,Shang Z,Lin G

更新日期：2019-01-21 00:00:00

abstract：:Ultrashort optical pulses propagating in a dissipative nonlinear system can interact and bind stably, forming optical soliton molecules. Soliton molecules in ultrafast lasers are under intense research focus and present striking analogies with their matter molecules counterparts. The recent development of real-time sp...

journal_title：Nature communications

authors： Wang ZQ,Nithyanandan K,Coillet A,Tchofo-Dinda P,Grelu P

更新日期：2019-02-19 00:00:00

abstract：:Conventional epitaxy of semiconductor films requires a compatible single crystalline substrate and precisely controlled growth conditions, which limit the price competitiveness and versatility of the process. We demonstrate substrate-tolerant nano-heteroepitaxy (NHE) of high-quality formamidinium-lead-tri-iodide (FAPb...

journal_title：Nature communications

authors： Lee JW,Tan S,Han TH,Wang R,Zhang L,Park C,Yoon M,Choi C,Xu M,Liao ME,Lee SJ,Nuryyeva S,Zhu C,Huynh K,Goorsky MS,Huang Y,Pan X,Yang Y

更新日期：2020-11-02 00:00:00

abstract：:The Schrödinger equation is a fundamental equation to describe the wave function of a quantum-mechanical system. The similar forms between the Schrödinger equation and the paraxial wave equation allow a paradigm shift from the quantum mechanics to classical fields, opening up a plethora of interesting phenomena includ...

journal_title：Nature communications

authors： Shen YX,Peng YG,Cai F,Huang K,Zhao DG,Qiu CW,Zheng H,Zhu XF

更新日期：2019-07-30 00:00:00

abstract：:Thin films of several microns in thickness are ubiquitously used in packaging, electronics, and acoustic sensors. Here we demonstrate that natural wood can be directly converted into an ultrathin film with a record-small thickness of less than 10 μm through partial delignification followed by densification. Benefiting...

journal_title：Nature communications

authors： Gan W,Chen C,Kim HT,Lin Z,Dai J,Dong Z,Zhou Z,Ping W,He S,Xiao S,Yu M,Hu L

更新日期：2019-11-08 00:00:00

abstract：:The ability to fabricate nanoscale domains of uniform size in two-dimensional materials could potentially enable new applications in nanoelectronics and the development of innovative metamaterials. However, achieving even minimal control over the growth of two-dimensional lateral heterostructures at such extreme dimen...

journal_title：Nature communications

authors： Camilli L,Jørgensen JH,Tersoff J,Stoot AC,Balog R,Cassidy A,Sadowski JT,Bøggild P,Hornekær L

更新日期：2017-06-29 00:00:00

abstract：:Glucocorticoids are among the most commonly used anti-inflammatory agents. Despite the enormous efforts in elucidating the glucocorticoid-mediated anti-inflammatory actions, how glucocorticoids tightly control overactive inflammatory response is not fully understood. Here we show that glucocorticoids suppress bacteria...

journal_title：Nature communications

authors： Miyata M,Lee JY,Susuki-Miyata S,Wang WY,Xu H,Kai H,Kobayashi KS,Flavell RA,Li JD

更新日期：2015-01-14 00:00:00

abstract：:Nervous systems exhibit myriad cell types, but understanding how this diversity arises is hampered by the difficulty to visualize and genetically-probe specific lineages, especially at early developmental stages prior to expression of unique molecular markers. Here, we use a genetic immortalization method to analyze t...

journal_title：Nature communications

authors： Chai PC,Cruchet S,Wigger L,Benton R

更新日期：2019-02-07 00:00:00

abstract：:Hydrogen can facilitate the detachment of protective oxide layer off metals and alloys. The degradation is usually exacerbated at elevated temperatures in many industrial applications; however, its origin remains poorly understood. Here by heating hydrogenated aluminium inside an environmental transmission electron mi...

journal_title：Nature communications

authors： Li M,Xie DG,Ma E,Li J,Zhang XX,Shan ZW

更新日期：2017-02-20 00:00:00

abstract：:Long-term depression (LTD) underlies learning and memory in various brain regions. Although postsynaptic AMPA receptor trafficking mediates LTD, its underlying molecular mechanisms remain largely unclear. Here we show that stargazin, a transmembrane AMPA receptor regulatory protein, forms a ternary complex with adapto...

journal_title：Nature communications

authors： Matsuda S,Kakegawa W,Budisantoso T,Nomura T,Kohda K,Yuzaki M

更新日期：2013-01-01 00:00:00

abstract：:A Correction to this paper has been published: https://doi.org/10.1038/s41467-020-20006-5. ...

journal_title：Nature communications

authors： Escalera-Zamudio M,Golden M,Gutiérrez B,Thézé J,Keown JR,Carrique L,Bowden TA,Pybus OG

更新日期：2020-11-23 00:00:00

abstract：:The interband cascade laser differs from any other class of semiconductor laser, conventional or cascaded, in that most of the carriers producing population inversion are generated internally, at semimetallic interfaces within each stage of the active region. Here we present simulations demonstrating that all previous...

journal_title：Nature communications

authors： Vurgaftman I,Bewley WW,Canedy CL,Kim CS,Kim M,Merritt CD,Abell J,Lindle JR,Meyer JR

更新日期：2011-12-13 00:00:00