Distribution of sulfamonomethoxine and trimethoprim in egg yolk and white.

Abstract:

:The distribution of sulfamonomethoxine (SMM) and trimethoprim (TMP) in egg yolk and white was measured during and after administration of a SMM/TMP combination in laying hens in doses of 8 g l(-)(1) and 12 g l(-)(1) in drinking water for 7 days. The SMM concentration reached maximal levels on day 2 of the post-treatment period for both doses (μg kg(-)(1)): 5920 and 9453 in yolk; 4831 and 6050 in white, in doses 1 and 2, respectively. Significant differences in the SMM and TMP concentrations between yolk and white in post treatment period were found. SMM dropped below the LOD (1.9 μg kg(-1)) in yolk after day 16 and 19 for doses 1 and 2. TMP reached maximal levels on day 3 after drug administration for doses 1 and 2 (μg kg(-)(1)): 6521 and 7329 in yolk, 1370 and 1539 in white. TMP residues were measured above LOD (0.3 μg kg(-)(1)) in yolk for both doses on day 37 post-treatment.

journal_name

Food Chem

journal_title

Food chemistry

authors

Bilandžić N,Božić Đ,Kolanović BS,Varenina I,Cvetnić L,Cvetnić Ž

doi

10.1016/j.foodchem.2015.01.076

subject

Has Abstract

pub_date

2015-07-01 00:00:00

pages

32-7

eissn

0308-8146

issn

1873-7072

pii

S0308-8146(15)00087-4

journal_volume

178

pub_type

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