Abstract：
:Prism adaptation (PA) is a promising rehabilitation technique for visuo-spatial neglect, an attention disorder that is characterized by spatial attention deficits (i.e., deficits in orienting). PA involves visuo-motor adaptation to rightward shifting prism goggles. Following goggle removal, this adaptation results in leftward shifts in visuo-motor aiming and amelioration of spatial neglect. Even though some studies clearly support the beneficial effects of PA for spatial neglect, not all studies find benefits, thus it remains unclear how PA effects could be improved. Taking advantage of the known interactions between orienting and alerting reported in the attention literature (i.e., alerting enhances orienting function; e.g., Ishigami and Klein in J Individ Differ 30:220-237. doi: 10.1027/1614-0001.30.4.220 , 2009, in J Neurosci Methods 190:117-28. doi: 10.1016/j.jneumeth.2010.04.019 , 2010; Robertson et al. in Nature 395:169-72. doi: 10.1038/25993 , 1998), we examined the effects of alerting tones on PA with healthy young and older adults. We found that the effects of alerting on PA with young adults were negative, while there was a positive effect with older adults, specifically on a visuo-motor outcome task. Thus, enhancement of PA effects by alerting may be age specific and task specific. Therefore, we can conclude that while the impact of alerting tones is not always positive, further research in patients with neglect may be warranted.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Kintzel F,Ishigami Y,Eskes GAdoi
10.1007/s00221-015-4218-8subject
Has Abstractpub_date
2015-05-01 00:00:00pages
1441-54issue
5eissn
0014-4819issn
1432-1106journal_volume
233pub_type
杂志文章,随机对照试验abstract：:Postural instability evokes cortical and autonomic reactions in addition to the primary compensatory response, and it is hypothesized that these responses may be related to underlying affective influences such as tonic physiological arousal. The purpose of this study was to determine whether perturbation-evoked cortic...
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journal_title：Experimental brain research
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journal_title：Experimental brain research
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journal_title：Experimental brain research
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更新日期：2001-06-01 00:00:00
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journal_title：Experimental brain research
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