Abstract:
:This editorial discusses the application of a novel brain imaging analysis technique in the assessment of neuroanatomical dysconnectivity in psychotic illnesses. There has long been a clinical interest in psychosis as a disconnection syndrome. In recent years graph theory metrics have been applied to functional and structural imaging datasets to derive measures of brain connectivity, which represent the efficiency of brain networks. These metrics can be derived from structural neuroimaging datasets acquired using diffusion imaging whereby cortical structures are parcellated into nodes and white matter tracts represent edges connecting these nodes. Furthermore neuroanatomical measures of connectivity may be decoupled from measures of physiological connectivity as assessed using functional imaging, underpinning the need for multi-modal imaging approaches to probe brain networks. Studies to date have reported a number of structural brain connectivity abnormalities associated with schizophrenia that carry potential as illness biomarkers. Structural connectivity abnormalities have also been reported in well patients with bipolar disorder and in unaffected relatives of patients with schizophrenia. Such connectivity metrics may represent clinically relevant biomarkers in studies employing a longitudinal design of illness course in psychosis.
journal_name
Epidemiol Psychiatr Scijournal_title
Epidemiology and psychiatric sciencesauthors
O'Donoghue S,Cannon DM,Perlini C,Brambilla P,McDonald Cdoi
10.1017/S2045796015000074subject
Has Abstractpub_date
2015-08-01 00:00:00pages
298-302issue
4eissn
2045-7960issn
2045-7979pii
S2045796015000074journal_volume
24pub_type
杂志文章abstract::Diffusion tensor imaging (DTI) is a neuroimaging technique with a potential to elucidate white matter integrity. Recently, it has been used in the field of psychiatry to further understand the pathophysiology of major diseases, including bipolar disorder (BD). This review sought to focus on existing DTI findings on wh...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/s2045796011000229
更新日期:2011-06-01 00:00:00
abstract:AIMS:For nearly a century, the incidence of cancer in people with schizophrenia was lower than in the general population. In the recent decade, the relationship between cancer and schizophrenia has become obscured. Thus, we investigated the cancer risk among young and middle-aged patients with schizophrenia. METHODS:R...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796016000883
更新日期:2018-04-01 00:00:00
abstract:AIMS:Little is known about the potential health impact of police encounters despite a ubiquitous police presence in many disadvantaged urban environments. In this paper, we assess whether persistent or aggressive interactions with the police are associated with poor mental health outcomes in a sample of primarily low-i...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796019000015
更新日期:2019-02-05 00:00:00
abstract:AIMS:Incorporating consumer perspectives into mental health services design is important in working to deliver recovery-oriented care. One of the challenges faced in mental health rehabilitation services is limited consumer engagement with the available support. Listening to consumers' expectations of mental health ser...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796017000749
更新日期:2019-08-01 00:00:00
abstract:OBJECTIVE:The primary goal was to identify risk factors for post-surgical depression in subjects operated on for drug-resistant epilepsy. Secondary goals were to confirm the high rate of depression in subjects suffering from epilepsy (prior to surgery) and to look for first post-surgical depressive episode. METHODS:Ca...
journal_title:Epidemiology and psychiatric sciences
pub_type: 信件
doi:10.1017/s2045796011000175
更新日期:2011-03-01 00:00:00
abstract::Aims. To assess the breadth of mental and substance coverage in the Cochrane review system. Methods. All mental health and substance entries were identified from the 2005 to April 2012 Cochrane Database of Systematic Reviews. Results. A total of 1019 entries focused on mental health or substance misuse, with 698 (68.5...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章,评审
doi:10.1017/S2045796012000455
更新日期:2013-06-01 00:00:00
abstract::When developing accessible, affordable and effective mental health systems, exchange of data between countries is an important moving force towards better mental health care. Unfortunately, health information systems in most countries are weak in the field of mental health, and comparability of data is low. Special in...
journal_title:Epidemiology and psychiatric sciences
pub_type: 社论
doi:10.1017/s2045796011000060
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND:Studies in urban areas identified environmental risk factors for mental illness, but little research on this topic has been performed in rural areas. METHODS:Hospital admission rates were computed for 174 rural municipalities in the catchment area of the state psychiatric hospital in Günzburg in years 2006 ...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796012000157
更新日期:2012-12-01 00:00:00
abstract::Depression in the elderly is common and exhibits a distinctive phenomenology, due to neurobiological, physiological, psychological and social changes related to ageing. Most elderly with depression are managed in primary health care. Although the number of scientific publications related to geriatric psychiatry has in...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章,评审
doi:10.1017/S204579601200025X
更新日期:2012-09-01 00:00:00
abstract:AIMS:To examine the impact of multiple psychiatric disorders over the lifetime on risk of mortality in the general population. METHODS:Data came from a random community-based sample of 1397 adults in Atlantic Canada, recruited in 1992. Major depression, dysthymia, panic disorder, generalised anxiety disorder and alcoh...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796018000859
更新日期:2019-02-04 00:00:00
abstract:BACKGROUND:Population-based studies have identified that delusional-like experiences (DLEs) are common in the general population. While there is a large literature exploring the relationship between poor social support and risk of mental illness, there is a lack of empirical data examining the association of poor socia...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796011000862
更新日期:2012-06-01 00:00:00
abstract:AIMS:Few studies have compared time trends for the incidence of psychosis. To date, the results have been inconsistent, showing a decline, an increase or no significant change. As far as we know, no studies explored changes in prevalence of early risk factors. The aim of this study was to investigate differences in ear...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796016000123
更新日期:2017-06-01 00:00:00
abstract:AIMS:Young adults with early psychosis want to pursue normal roles - education and employment. This paper summarises the empirical literature on the effectiveness of early intervention programmes for employment and education outcomes. METHODS:We conducted a systematic review of employment/education outcomes for early ...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796014000419
更新日期:2015-10-01 00:00:00
abstract::Aims. Prevalence and covariates of subclinical psychosis have gained increased interest in the context of early identification and treatment of persons at risk for psychosis. Methods. We analysed 9829 adults representative of the general population within the canton of Zurich, Switzerland. Two psychosis syndromes, der...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796013000681
更新日期:2015-02-01 00:00:00
abstract::Aims. High numbers of psychiatric service users experience domestic violence, yet limited interventions exist for these victims. We piloted a domestic violence intervention for community mental health services to explore the feasibility of a future cluster randomized controlled trial. Methods. Quasi-experimental contr...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796013000206
更新日期:2014-03-01 00:00:00
abstract::The 'at-risk' criteria are a useful paradigm for investigating the psychological, neurocognitive, neurobiological and genetic risk factors for psychosis, specifically schizophrenia. To date, the primary outcome of interest in at-risk research has been the development of psychotic disorder, whereby patients are categor...
journal_title:Epidemiology and psychiatric sciences
pub_type: 社论
doi:10.1017/S2045796012000388
更新日期:2012-12-01 00:00:00
abstract:AIMS:Childhood maltreatment and a family history of a schizophrenia spectrum disorder (SSD) are each associated with social-emotional dysfunction in childhood. Both are also strong risk factors for adult SSDs, and social-emotional dysfunction in childhood may be an antecedent of these disorders. We used data from a lar...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S204579601600055X
更新日期:2017-12-01 00:00:00
abstract::In July 2015, the Canadian Agency for Drugs and Technologies in Health (CADTH) released a Rapid Response report summary, with a critical appraisal, on discontinuation strategies for patients with long-term benzodiazepines (BDZ) use. The CADTH document is a review of the literature. It includes studies whose interventi...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796016000032
更新日期:2016-06-01 00:00:00
abstract::Lately on these pages, a discussion is going on over the opportunity of the use of the definition 'outsider'. Especially in the USA, it is judged as demeaning, discriminating and inappropriate, whilst in Europe, it is used in a much more unconcerned way. Mr Gioni curator of numerous international exhibitions including...
journal_title:Epidemiology and psychiatric sciences
pub_type: 传,历史文章,杂志文章
doi:10.1017/S2045796018000550
更新日期:2018-12-01 00:00:00
abstract:AIM:To determine whether disparities exist in mental health care provision to immigrants and Italian citizens with severe mental illness in Bologna, Italy. METHODS:Records of prevalent cases on 31/12/2010 with severe mental illness and ≥1 contact with Community Mental Health Centers in 2011 were extracted from the men...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796014000250
更新日期:2015-08-01 00:00:00
abstract:AIMS:Research demonstrates elevated levels of common mental disorders among Syrian refugees, but the majority of studies have, to date, focused on adult populations. This study aims to estimate the prevalence of depression, anxiety and post-traumatic stress disorder (PTSD) among Syrian children and adolescents living i...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796020001079
更新日期:2020-12-10 00:00:00
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journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S204579601400050X
更新日期:2015-02-01 00:00:00
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journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796020000396
更新日期:2020-05-06 00:00:00
abstract:AIMS:The purpose of this review is to examine the replication attempts of psychotherapy clinical trials for depression and anxiety. We focus specifically on replications of trials that exhibit large differences between psychotherapies. The replicability of these trials is especially important for meta-analysis, where t...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章,meta分析,评审
doi:10.1017/S2045796020000402
更新日期:2020-05-15 00:00:00
abstract:AIMS:To explore the role of psychiatric admission, diagnosis and reported unfair treatment in the relationship between ethnicity and mistrust of mental health services. METHODS:The Mental Illness-Related Investigations on Discrimination (MIRIAD) study was a cross-sectional study of 202 individuals using secondary ment...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796014000158
更新日期:2015-06-01 00:00:00
abstract::Psychiatry is having a great time. Over the last few years, we have seen an exceptional explosion in neuroscience knowledge, and especially in our understanding of the molecular mechanisms through which environmental and genetic factors affect the brain and regulate behaviour, while at the same interacting with periph...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S204579601500089X
更新日期:2016-04-01 00:00:00
abstract::Mental health care in the second half of the 20th century in much of the developed world has been dominated by the move out from large asylums. Both in response to this move and to make it possible, a pattern of care has evolved which is most commonly referred to as 'Community Psychiatry'. This narrative review descri...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796014000560
更新日期:2014-12-01 00:00:00
abstract::Psychiatry is in one of its regular crises. It is a crisis of its diagnostic systems despite - perhaps because - of the recurrent claims about the extent of diagnosable 'brain disorders'. It is a crisis of its explanatory systems despite - perhaps because - of its current wager on the brain as the ultimate locus for e...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796015000621
更新日期:2016-04-01 00:00:00
abstract::There have been repeated calls to include mental health in the sustainable development goals (SDGs), arguing that progress in development will not be made without improvements in mental health. Although these calls are starting to gain political traction, currently only a tiny fraction of international development wor...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796015000049
更新日期:2015-04-01 00:00:00
abstract::With cancer incidence increasing over time worldwide, attention to the burden of psychiatric and psychosocial consequences of the disease is now mandatory for both cancer and mental health care professionals. Psychiatric disorders have been shown to affect at least 30-35% of cancer patients during all phases of the di...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796019000866
更新日期:2020-01-09 00:00:00