Abstract:
:The principle of pragmatism in clinical trials has been broadly recognised as a way to close the gap between research and practice. In this contribution, we argue that the conduct of pragmatic clinical trials in Europe may be hampered by poor implementation of current European Union's Clinical Trial Regulation No. 536/2014.
journal_name
Epidemiol Psychiatr Scijournal_title
Epidemiology and psychiatric sciencesauthors
Ostuzzi G,Gastaldon C,Petrini C,Godman B,Barbui Cdoi
10.1017/S2045796020000396subject
Has Abstractpub_date
2020-05-06 00:00:00pages
e126eissn
2045-7960issn
2045-7979pii
S2045796020000396journal_volume
29pub_type
杂志文章abstract:AIMS:The purpose of this review is to examine the replication attempts of psychotherapy clinical trials for depression and anxiety. We focus specifically on replications of trials that exhibit large differences between psychotherapies. The replicability of these trials is especially important for meta-analysis, where t...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章,meta分析,评审
doi:10.1017/S2045796020000402
更新日期:2020-05-15 00:00:00
abstract:AIMS:Young adults with early psychosis want to pursue normal roles - education and employment. This paper summarises the empirical literature on the effectiveness of early intervention programmes for employment and education outcomes. METHODS:We conducted a systematic review of employment/education outcomes for early ...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796014000419
更新日期:2015-10-01 00:00:00
abstract:AIM:Previous work suggests that the Dutch variant of assertive community treatment (ACT), known as Function ACT (FACT), may be effective in increasing symptomatic remission rates when replacing a system of hospital-based care and separate community-based facilities. FACT guidelines propose a different pattern of psychi...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/s2045796011000369
更新日期:2011-09-01 00:00:00
abstract:AIMS:Decades of research show that people with schizophrenia have an increased risk of death from cancer; however, the relationship between schizophrenia and cancer incidence remains less clear. This population-based study investigates the incidence of seven common types of cancer among people with a hospital diagnosis...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S204579602000044X
更新日期:2020-05-28 00:00:00
abstract:AIMS:Suicidal behaviour is prevalent among adolescents and is a significant predictor of future suicide attempts (SAs) and suicide death. Data on the prevalence and epidemiological characteristics of suicidal behaviour in Chinese adolescents are limited. This study was aimed to examine the prevalence, characteristics a...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796017000488
更新日期:2019-06-01 00:00:00
abstract:AIMS:This systematic review compiled evidence on interventions to reduce mental health-related stigma among medical and nursing students in low- and middle-income countries (LMICs). Primary outcomes were stigmatising attitudes and discriminatory behaviours. METHODS:Data collection included two strategies. First, previ...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796019000167
更新日期:2019-04-01 00:00:00
abstract::This editorial discusses the application of a novel brain imaging analysis technique in the assessment of neuroanatomical dysconnectivity in psychotic illnesses. There has long been a clinical interest in psychosis as a disconnection syndrome. In recent years graph theory metrics have been applied to functional and st...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796015000074
更新日期:2015-08-01 00:00:00
abstract::Background. Interest in features of our local environments that may promote better mental health and wellbeing continues to rise among decision makers. Our purpose was to highlight a selection of these challenges and some promising avenues for enhancing the quality of evidence. Method. An analysis of approximately 267...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S204579601400050X
更新日期:2015-02-01 00:00:00
abstract:BACKGROUND:Aims of this study are to explore the associations of readmission to psychiatric hospital over time, to develop a statistical model for early readmission to psychiatric hospital and to assess the feasibility of predicting early readmission. METHOD:The sample comprised 7891 general psychiatric discharges in ...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796015000128
更新日期:2016-04-01 00:00:00
abstract::Diffusion tensor imaging (DTI) is a neuroimaging technique with a potential to elucidate white matter integrity. Recently, it has been used in the field of psychiatry to further understand the pathophysiology of major diseases, including bipolar disorder (BD). This review sought to focus on existing DTI findings on wh...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/s2045796011000229
更新日期:2011-06-01 00:00:00
abstract::Lately on these pages, a discussion is going on over the opportunity of the use of the definition 'outsider'. Especially in the USA, it is judged as demeaning, discriminating and inappropriate, whilst in Europe, it is used in a much more unconcerned way. Mr Gioni curator of numerous international exhibitions including...
journal_title:Epidemiology and psychiatric sciences
pub_type: 传,历史文章,杂志文章
doi:10.1017/S2045796018000550
更新日期:2018-12-01 00:00:00
abstract::The relationship between poverty and mental health is indisputable. However, to have an influence on the next set of sustainable global development goals, we need to understand the causal relationships between social determinants such as poverty, inequality, lack of education and unemployment; thereby clarifying which...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796015000086
更新日期:2015-04-01 00:00:00
abstract::The use of psychoactive, potentially dependence-producing substances is highly prevalent around the world, and contributes substantially to global disease burden. There is a major gap between the need for treatment for substance use disorders. Changes proposed for the classification of substance use disorders in the E...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796017000622
更新日期:2018-06-01 00:00:00
abstract:AIM:Eating disorders have increasingly become a public health concern globally. This study aimed to reveal the burden of eating disorders at the global, regional and national levels using the Global Burden of Disease (GBD) Study 2017 data. METHODS:We extracted the age-standardised rates (ASRs) of prevalence and disabi...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796020001055
更新日期:2020-12-07 00:00:00
abstract:AIMS:Little is known about the potential health impact of police encounters despite a ubiquitous police presence in many disadvantaged urban environments. In this paper, we assess whether persistent or aggressive interactions with the police are associated with poor mental health outcomes in a sample of primarily low-i...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796019000015
更新日期:2019-02-05 00:00:00
abstract:AIMS:Establishing the minimum clinically important difference (MCID) in functioning and cognition is essential to the interpretation of the research and clinical work conducted in bipolar disorders (BD). The present study aimed to estimate the MCID for the Functioning Assessment Short Test (FAST) and a battery of neuro...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796020000566
更新日期:2020-07-20 00:00:00
abstract::Increasing numbers of young adults need continued support for their attention deficit hyperactivity disorder (ADHD) beyond the age-boundary for children's services. The sparse literature on transition in general suggests patchy provision and huge gaps in transitional care, but also that young people with ADHD and othe...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796019000817
更新日期:2020-01-09 00:00:00
abstract::Aggressive or antisocial behaviours with violations of social rules are the main features of disruptive behaviour disorders (DBDs), which are developmental diseases and include conduct disorder and oppositional defiant disorder. In the last decade, several efforts have been made to shed light on the biological underpi...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/s2045796011000692
更新日期:2012-03-01 00:00:00
abstract:AIMS:The use of Alzheimer disease medication for the treatment of dementia symptoms has shown significant benefits with regards to functional and cognitive outcomes as well as nursing home placement (NHP) and mortality. Hospitalisations in these patient groups are characterised by extended length of stays (LOS), freque...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796019000702
更新日期:2019-11-14 00:00:00
abstract::Aims. To assess the breadth of mental and substance coverage in the Cochrane review system. Methods. All mental health and substance entries were identified from the 2005 to April 2012 Cochrane Database of Systematic Reviews. Results. A total of 1019 entries focused on mental health or substance misuse, with 698 (68.5...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章,评审
doi:10.1017/S2045796012000455
更新日期:2013-06-01 00:00:00
abstract::There have been repeated calls to include mental health in the sustainable development goals (SDGs), arguing that progress in development will not be made without improvements in mental health. Although these calls are starting to gain political traction, currently only a tiny fraction of international development wor...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796015000049
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:Population-based studies have identified that delusional-like experiences (DLEs) are common in the general population. While there is a large literature exploring the relationship between poor social support and risk of mental illness, there is a lack of empirical data examining the association of poor socia...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796011000862
更新日期:2012-06-01 00:00:00
abstract::With cancer incidence increasing over time worldwide, attention to the burden of psychiatric and psychosocial consequences of the disease is now mandatory for both cancer and mental health care professionals. Psychiatric disorders have been shown to affect at least 30-35% of cancer patients during all phases of the di...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796019000866
更新日期:2020-01-09 00:00:00
abstract:AIMS:A substantial proportion of persons with mental disorders seek treatment from complementary and alternative medicine (CAM) professionals. However, data on how CAM contacts vary across countries, mental disorders and their severity, and health care settings is largely lacking. The aim was therefore to investigate t...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796017000774
更新日期:2018-12-01 00:00:00
abstract:AIMS:Incorporating consumer perspectives into mental health services design is important in working to deliver recovery-oriented care. One of the challenges faced in mental health rehabilitation services is limited consumer engagement with the available support. Listening to consumers' expectations of mental health ser...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796017000749
更新日期:2019-08-01 00:00:00
abstract:AIMS:To determine the association between the sleep duration and the risk of all-cause mortality in adults. METHODS:A search strategy was conducted in the MEDLINE, CENTRAL, EMBASE and LILACS databases. Searches were also conducted in other databases and unpublished literature. Cohort studies were included without lang...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章,meta分析
doi:10.1017/S2045796018000379
更新日期:2019-10-01 00:00:00
abstract::Aims. High numbers of psychiatric service users experience domestic violence, yet limited interventions exist for these victims. We piloted a domestic violence intervention for community mental health services to explore the feasibility of a future cluster randomized controlled trial. Methods. Quasi-experimental contr...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796013000206
更新日期:2014-03-01 00:00:00
abstract::Mental health care in the second half of the 20th century in much of the developed world has been dominated by the move out from large asylums. Both in response to this move and to make it possible, a pattern of care has evolved which is most commonly referred to as 'Community Psychiatry'. This narrative review descri...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796014000560
更新日期:2014-12-01 00:00:00
abstract::Aims. Little is known about how the rates and characteristics of mental health service users in unpaid work, training and study compare with those in paid employment. Methods. From staff report and patient records, 1353 mental health service users of seven Community Mental Health Teams in two London boroughs were cate...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796012000534
更新日期:2013-06-01 00:00:00
abstract::Autism spectrum disorder (ASD) is a neurodevelopmental disorder mainly characterised by deficits in social communication as well as by narrow patterns of behaviour and interests (American Psychiatric Association, 2013), often accompanied by language, intellectual and sensory impairments. The severity of these impairme...
journal_title:Epidemiology and psychiatric sciences
pub_type: 杂志文章
doi:10.1017/S2045796017000610
更新日期:2018-04-01 00:00:00