Neuroscience, mental health and the immune system: overcoming the brain-mind-body trichotomy.


:Psychiatry is having a great time. Over the last few years, we have seen an exceptional explosion in neuroscience knowledge, and especially in our understanding of the molecular mechanisms through which environmental and genetic factors affect the brain and regulate behaviour, while at the same interacting with peripheral ('body') functions. While this explosion, and its translational implications, can be seen across a variety of fields, this editorial will focus on one particular area where these developments have been more noticeable: the interaction between neuroscience, mental health and the immune system. This editorial will focus on the broader impact of this discipline as an example of successful translational neuroscience overcoming the brain-mind-body trichotomy.


Pariante CM




Has Abstract


2016-04-01 00:00:00














  • Discontinuing benzodiazepines: best practices.

    abstract::In July 2015, the Canadian Agency for Drugs and Technologies in Health (CADTH) released a Rapid Response report summary, with a critical appraisal, on discontinuation strategies for patients with long-term benzodiazepines (BDZ) use. The CADTH document is a review of the literature. It includes studies whose interventi...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Guaiana G,Barbui C

    更新日期:2016-06-01 00:00:00

  • Complementary and alternative medicine contacts by persons with mental disorders in 25 countries: results from the World Mental Health Surveys.

    abstract:AIMS:A substantial proportion of persons with mental disorders seek treatment from complementary and alternative medicine (CAM) professionals. However, data on how CAM contacts vary across countries, mental disorders and their severity, and health care settings is largely lacking. The aim was therefore to investigate t...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: de Jonge P,Wardenaar KJ,Hoenders HR,Evans-Lacko S,Kovess-Masfety V,Aguilar-Gaxiola S,Al-Hamzawi A,Alonso J,Andrade LH,Benjet C,Bromet EJ,Bruffaerts R,Bunting B,Caldas-de-Almeida JM,Dinolova RV,Florescu S,de Girolamo G,G

    更新日期:2018-12-01 00:00:00

  • Effects of maltreatment and parental schizophrenia spectrum disorders on early childhood social-emotional functioning: a population record linkage study.

    abstract:AIMS:Childhood maltreatment and a family history of a schizophrenia spectrum disorder (SSD) are each associated with social-emotional dysfunction in childhood. Both are also strong risk factors for adult SSDs, and social-emotional dysfunction in childhood may be an antecedent of these disorders. We used data from a lar...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Matheson SL,Kariuki M,Green MJ,Dean K,Harris F,Tzoumakis S,Tarren-Sweeney M,Brinkman S,Chilvers M,Sprague T,Carr VJ,Laurens KR

    更新日期:2017-12-01 00:00:00

  • 'At-risk' for psychosis research: where are we heading?

    abstract::The 'at-risk' criteria are a useful paradigm for investigating the psychological, neurocognitive, neurobiological and genetic risk factors for psychosis, specifically schizophrenia. To date, the primary outcome of interest in at-risk research has been the development of psychotic disorder, whereby patients are categor...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 社论


    authors: Lin A,Nelson B,Yung AR

    更新日期:2012-12-01 00:00:00

  • Neuroscience and the future for mental health?

    abstract::Psychiatry is in one of its regular crises. It is a crisis of its diagnostic systems despite - perhaps because - of the recurrent claims about the extent of diagnosable 'brain disorders'. It is a crisis of its explanatory systems despite - perhaps because - of its current wager on the brain as the ultimate locus for e...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Rose N

    更新日期:2016-04-01 00:00:00

  • Alzheimer's disease medication and outcomes of hospitalisation among patients with dementia.

    abstract:AIMS:The use of Alzheimer disease medication for the treatment of dementia symptoms has shown significant benefits with regards to functional and cognitive outcomes as well as nursing home placement (NHP) and mortality. Hospitalisations in these patient groups are characterised by extended length of stays (LOS), freque...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Möllers T,Perna L,Stocker H,Ihle P,Schubert I,Schöttker B,Frölich L,Bauer J,Brenner H

    更新日期:2019-11-14 00:00:00

  • Employment and educational outcomes in early intervention programmes for early psychosis: a systematic review.

    abstract:AIMS:Young adults with early psychosis want to pursue normal roles - education and employment. This paper summarises the empirical literature on the effectiveness of early intervention programmes for employment and education outcomes. METHODS:We conducted a systematic review of employment/education outcomes for early ...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Bond GR,Drake RE,Luciano A

    更新日期:2015-10-01 00:00:00

  • Disparities in mental health care provision to immigrants with severe mental illness in Italy.

    abstract:AIM:To determine whether disparities exist in mental health care provision to immigrants and Italian citizens with severe mental illness in Bologna, Italy. METHODS:Records of prevalent cases on 31/12/2010 with severe mental illness and ≥1 contact with Community Mental Health Centers in 2011 were extracted from the men...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Rucci P,Piazza A,Perrone E,Tarricone I,Maisto R,Donegani I,Spigonardo V,Berardi D,Fantini MP,Fioritti A

    更新日期:2015-08-01 00:00:00

  • Community psychiatry's achievements.

    abstract::Mental health care in the second half of the 20th century in much of the developed world has been dominated by the move out from large asylums. Both in response to this move and to make it possible, a pattern of care has evolved which is most commonly referred to as 'Community Psychiatry'. This narrative review descri...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Burns T

    更新日期:2014-12-01 00:00:00

  • Do psychiatric units at general hospitals attract less stigmatizing attitudes compared with psychiatric hospitals?

    abstract::Aims. It is often assumed that psychiatric units at general hospitals attract less stigma than do specialized psychiatric hospitals, but so far this has not been examined empirically. Methods. We conducted a representative population survey in Germany (n = 2410) in order to compare attitudes towards psychiatric units ...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Schomerus G,Matschinger H,Angermeyer MC

    更新日期:2013-06-01 00:00:00

  • Cancer incidence in young and middle-aged people with schizophrenia: nationwide cohort study in Taiwan, 2000-2010.

    abstract:AIMS:For nearly a century, the incidence of cancer in people with schizophrenia was lower than in the general population. In the recent decade, the relationship between cancer and schizophrenia has become obscured. Thus, we investigated the cancer risk among young and middle-aged patients with schizophrenia. METHODS:R...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Chen LY,Hung YN,Chen YY,Yang SY,Pan CH,Chen CC,Kuo CJ

    更新日期:2018-04-01 00:00:00

  • What does the latest meta-analysis really tell us about antidepressants?

    abstract::A recent meta-analysis of antidepressant trials is the largest conducted to date. Although it claims to prove antidepressant effectiveness beyond dispute, the main outcome is response rates, which are derived from continuous data in a process that can inflate differences between groups. The standardised mean differenc...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Moncrieff J

    更新日期:2018-10-01 00:00:00

  • Persistent and aggressive interactions with the police: potential mental health implications.

    abstract:AIMS:Little is known about the potential health impact of police encounters despite a ubiquitous police presence in many disadvantaged urban environments. In this paper, we assess whether persistent or aggressive interactions with the police are associated with poor mental health outcomes in a sample of primarily low-i...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Hirschtick JL,Homan SM,Rauscher G,Rubin LH,Johnson TP,Peterson CE,Persky VW

    更新日期:2019-02-05 00:00:00

  • Prevalence of suicidal behaviour and associated factors in a large sample of Chinese adolescents.

    abstract:AIMS:Suicidal behaviour is prevalent among adolescents and is a significant predictor of future suicide attempts (SAs) and suicide death. Data on the prevalence and epidemiological characteristics of suicidal behaviour in Chinese adolescents are limited. This study was aimed to examine the prevalence, characteristics a...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Liu XC,Chen H,Liu ZZ,Wang JY,Jia CX

    更新日期:2019-06-01 00:00:00

  • Implementing evidence-based guidelines for managing depression in elderly patients: a Norwegian perspective.

    abstract::Depression in the elderly is common and exhibits a distinctive phenomenology, due to neurobiological, physiological, psychological and social changes related to ageing. Most elderly with depression are managed in primary health care. Although the number of scientific publications related to geriatric psychiatry has in...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章,评审


    authors: Aakhus E,Flottorp SA,Oxman AD

    更新日期:2012-09-01 00:00:00

  • Investigating 'place effects' on mental health: implications for population-based studies in psychiatry.

    abstract::Background. Interest in features of our local environments that may promote better mental health and wellbeing continues to rise among decision makers. Our purpose was to highlight a selection of these challenges and some promising avenues for enhancing the quality of evidence. Method. An analysis of approximately 267...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Astell-Burt T,Feng X

    更新日期:2015-02-01 00:00:00

  • Association of Attention deficit hyperactivity disorder and Kawasaki disease: a nationwide population-based cohort study.

    abstract:AIMS:The association between Kawasaki disease (KD) and Attention deficit hyperactivity disorder (ADHD) has rarely been studied. In this study, we investigated the hypothesis that KD may increase the risk of ADHD using a nationwide Taiwanese population-based claims database. METHODS:Our study cohort consisted of patien...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Kuo HC,Chang WC,Wang LJ,Li SC,Chang WP

    更新日期:2016-12-01 00:00:00

  • Trends in the prevalence and disability-adjusted life years of eating disorders from 1990 to 2017: results from the Global Burden of Disease Study 2017.

    abstract:AIM:Eating disorders have increasingly become a public health concern globally. This study aimed to reveal the burden of eating disorders at the global, regional and national levels using the Global Burden of Disease (GBD) Study 2017 data. METHODS:We extracted the age-standardised rates (ASRs) of prevalence and disabi...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Wu J,Liu J,Li S,Ma H,Wang Y

    更新日期:2020-12-07 00:00:00

  • Psychoses sans Frontieres: towards an interdisciplinary understanding of psychosis risk amongst migrants and their descendants.

    abstract::Understanding the excess risk of psychotic disorders in migrant and ethnic minority groups has long been an important research focus in psychiatric epidemiology and public mental health. Heterogeneity between migrant groups based on the region of origin, minority status and other socioeconomic factors may provide clue...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Dykxhoorn J,Kirkbride JB

    更新日期:2019-04-01 00:00:00

  • Risk factors for postoperative depression in 150 subjects treated for drug-resistant focal epilepsy.

    abstract:OBJECTIVE:The primary goal was to identify risk factors for post-surgical depression in subjects operated on for drug-resistant epilepsy. Secondary goals were to confirm the high rate of depression in subjects suffering from epilepsy (prior to surgery) and to look for first post-surgical depressive episode. METHODS:Ca...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 信件


    authors: Barbieri V,Cardinale F,Luoni A,Russo GL,Francione S,Tassi L,Sartori I,Castana L,Scarone S,Gambini O

    更新日期:2011-03-01 00:00:00

  • Lifetime experience of multiple common mental disorders and 19-year mortality: results from a Canadian population-based cohort.

    abstract:AIMS:To examine the impact of multiple psychiatric disorders over the lifetime on risk of mortality in the general population. METHODS:Data came from a random community-based sample of 1397 adults in Atlantic Canada, recruited in 1992. Major depression, dysthymia, panic disorder, generalised anxiety disorder and alcoh...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Kingsbury M,Sucha E,Horton NJ,Sampasa-Kanyinga H,Murphy JM,Gilman SE,Colman I

    更新日期:2019-02-04 00:00:00

  • Minimum clinically important differences for the Functioning Assessment Short Test and a battery of neuropsychological tests in bipolar disorders: results from the FACE-BD cohort.

    abstract:AIMS:Establishing the minimum clinically important difference (MCID) in functioning and cognition is essential to the interpretation of the research and clinical work conducted in bipolar disorders (BD). The present study aimed to estimate the MCID for the Functioning Assessment Short Test (FAST) and a battery of neuro...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Roux P,Brunet-Gouet E,Ehrminger M,Aouizerate B,Aubin V,Azorin JM,Bellivier F,Bougerol T,Courtet P,Dubertret C,Kahn JP,Leboyer M,Olié E,FondaMental Advanced Centers of Expertise in Bipolar Disorders (FACE-BD) Collaborators.,Et

    更新日期:2020-07-20 00:00:00

  • Video modeling for the development of personal hygiene skills in youth with autism spectrum disorder.

    abstract::Autism spectrum disorder (ASD) is a neurodevelopmental disorder mainly characterised by deficits in social communication as well as by narrow patterns of behaviour and interests (American Psychiatric Association, 2013), often accompanied by language, intellectual and sensory impairments. The severity of these impairme...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Piccin S,Crippa A,Nobile M,Hardan AY,Brambilla P

    更新日期:2018-04-01 00:00:00

  • Functional MRI studies in disruptive behaviour disorders.

    abstract::Aggressive or antisocial behaviours with violations of social rules are the main features of disruptive behaviour disorders (DBDs), which are developmental diseases and include conduct disorder and oppositional defiant disorder. In the last decade, several efforts have been made to shed light on the biological underpi...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Bellani M,Garzitto M,Brambilla P

    更新日期:2012-03-01 00:00:00

  • Poverty, inequality and a political economy of mental health.

    abstract::The relationship between poverty and mental health is indisputable. However, to have an influence on the next set of sustainable global development goals, we need to understand the causal relationships between social determinants such as poverty, inequality, lack of education and unemployment; thereby clarifying which...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Burns JK

    更新日期:2015-04-01 00:00:00

  • Area characteristics and admission rates of people with schizophrenia and affective disorders in a German rural catchment area.

    abstract:BACKGROUND:Studies in urban areas identified environmental risk factors for mental illness, but little research on this topic has been performed in rural areas. METHODS:Hospital admission rates were computed for 174 rural municipalities in the catchment area of the state psychiatric hospital in Günzburg in years 2006 ...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Losert C,Schmauß M,Becker T,Kilian R

    更新日期:2012-12-01 00:00:00

  • Exploring the predictors of early readmission to psychiatric hospital.

    abstract:BACKGROUND:Aims of this study are to explore the associations of readmission to psychiatric hospital over time, to develop a statistical model for early readmission to psychiatric hospital and to assess the feasibility of predicting early readmission. METHOD:The sample comprised 7891 general psychiatric discharges in ...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Tulloch AD,David AS,Thornicroft G

    更新日期:2016-04-01 00:00:00

  • Brain anatomy of autism spectrum disorders II. Focus on amygdala.

    abstract::This brief review encompasses the key findings of structural Magnetic Resonance Imaging (sMRI) research on amygdala volume in autism spectrum disorders (ASD). We also highlight the possible correlation between the autistic behavioural phenotype and amygdala alteration. ...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Bellani M,Calderoni S,Muratori F,Brambilla P

    更新日期:2013-12-01 00:00:00

  • In conversation with Massimiliano Gioni.

    abstract::Lately on these pages, a discussion is going on over the opportunity of the use of the definition 'outsider'. Especially in the USA, it is judged as demeaning, discriminating and inappropriate, whilst in Europe, it is used in a much more unconcerned way. Mr Gioni curator of numerous international exhibitions including...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 传,历史文章,杂志文章


    authors: Tansella C

    更新日期:2018-12-01 00:00:00

  • Mistrust of mental health services: ethnicity, hospital admission and unfair treatment.

    abstract:AIMS:To explore the role of psychiatric admission, diagnosis and reported unfair treatment in the relationship between ethnicity and mistrust of mental health services. METHODS:The Mental Illness-Related Investigations on Discrimination (MIRIAD) study was a cross-sectional study of 202 individuals using secondary ment...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Henderson RC,Williams P,Gabbidon J,Farrelly S,Schauman O,Hatch S,Thornicroft G,Bhugra D,Clement S,MIRIAD study group.

    更新日期:2015-06-01 00:00:00