Neuroscience, mental health and the immune system: overcoming the brain-mind-body trichotomy.


:Psychiatry is having a great time. Over the last few years, we have seen an exceptional explosion in neuroscience knowledge, and especially in our understanding of the molecular mechanisms through which environmental and genetic factors affect the brain and regulate behaviour, while at the same interacting with peripheral ('body') functions. While this explosion, and its translational implications, can be seen across a variety of fields, this editorial will focus on one particular area where these developments have been more noticeable: the interaction between neuroscience, mental health and the immune system. This editorial will focus on the broader impact of this discipline as an example of successful translational neuroscience overcoming the brain-mind-body trichotomy.


Pariante CM




Has Abstract


2016-04-01 00:00:00














  • Understanding the characteristics and mechanisms underlying suicide clusters in Australian youth: a comparison of cluster detection methods.

    abstract:AIMS:There is currently no gold-standard definition or method for identifying suicide clusters, resulting in considerable heterogeneity in the types of suicide clusters that are detected. This study sought to identify the characteristics, mechanisms and parameters of suicide clusters using three cluster detection metho...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Hill NTM,Too LS,Spittal MJ,Robinson J

    更新日期:2020-08-06 00:00:00

  • Employment and educational outcomes in early intervention programmes for early psychosis: a systematic review.

    abstract:AIMS:Young adults with early psychosis want to pursue normal roles - education and employment. This paper summarises the empirical literature on the effectiveness of early intervention programmes for employment and education outcomes. METHODS:We conducted a systematic review of employment/education outcomes for early ...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Bond GR,Drake RE,Luciano A

    更新日期:2015-10-01 00:00:00

  • Identifying the critical time points for mental health of asylum seekers and refugees in high-income countries.

    abstract:AIMS:High heterogeneity was found in the prevalence rates of mental disorders in adult asylum seekers and refugees in high-income countries. This may be related to different problems. Among them, there is a changing exposure to risk and protective factors for mental health at different phases of these people's life bef...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Giacco D

    更新日期:2019-10-02 00:00:00

  • European comparisons between mental health services.

    abstract::When developing accessible, affordable and effective mental health systems, exchange of data between countries is an important moving force towards better mental health care. Unfortunately, health information systems in most countries are weak in the field of mental health, and comparability of data is low. Special in...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 社论


    authors: Wahlbeck K

    更新日期:2011-03-01 00:00:00

  • Cancer incidence in young and middle-aged people with schizophrenia: nationwide cohort study in Taiwan, 2000-2010.

    abstract:AIMS:For nearly a century, the incidence of cancer in people with schizophrenia was lower than in the general population. In the recent decade, the relationship between cancer and schizophrenia has become obscured. Thus, we investigated the cancer risk among young and middle-aged patients with schizophrenia. METHODS:R...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Chen LY,Hung YN,Chen YY,Yang SY,Pan CH,Chen CC,Kuo CJ

    更新日期:2018-04-01 00:00:00

  • Prevalence of suicidal behaviour and associated factors in a large sample of Chinese adolescents.

    abstract:AIMS:Suicidal behaviour is prevalent among adolescents and is a significant predictor of future suicide attempts (SAs) and suicide death. Data on the prevalence and epidemiological characteristics of suicidal behaviour in Chinese adolescents are limited. This study was aimed to examine the prevalence, characteristics a...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Liu XC,Chen H,Liu ZZ,Wang JY,Jia CX

    更新日期:2019-06-01 00:00:00

  • Trends in work disability with mental diagnoses among social workers in Finland and Sweden in 2005-2012.

    abstract::Aims Social workers report high levels of stress and have an increased risk for hospitalisation with mental diagnoses. However, it is not known whether the risk of work disability with mental diagnoses is higher among social workers compared with other human service professionals. We analysed trends in work disability...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Rantonen O,Alexanderson K,Pentti J,Kjeldgård L,Hämäläinen J,Mittendorfer-Rutz E,Kivimäki M,Vahtera J,Salo P

    更新日期:2017-12-01 00:00:00

  • Complementary and alternative medicine contacts by persons with mental disorders in 25 countries: results from the World Mental Health Surveys.

    abstract:AIMS:A substantial proportion of persons with mental disorders seek treatment from complementary and alternative medicine (CAM) professionals. However, data on how CAM contacts vary across countries, mental disorders and their severity, and health care settings is largely lacking. The aim was therefore to investigate t...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: de Jonge P,Wardenaar KJ,Hoenders HR,Evans-Lacko S,Kovess-Masfety V,Aguilar-Gaxiola S,Al-Hamzawi A,Alonso J,Andrade LH,Benjet C,Bromet EJ,Bruffaerts R,Bunting B,Caldas-de-Almeida JM,Dinolova RV,Florescu S,de Girolamo G,G

    更新日期:2018-12-01 00:00:00

  • Implementing evidence-based guidelines for managing depression in elderly patients: a Norwegian perspective.

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    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章,评审


    authors: Aakhus E,Flottorp SA,Oxman AD

    更新日期:2012-09-01 00:00:00

  • What does the latest meta-analysis really tell us about antidepressants?

    abstract::A recent meta-analysis of antidepressant trials is the largest conducted to date. Although it claims to prove antidepressant effectiveness beyond dispute, the main outcome is response rates, which are derived from continuous data in a process that can inflate differences between groups. The standardised mean differenc...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Moncrieff J

    更新日期:2018-10-01 00:00:00

  • Poor implementation of the EU clinical trial regulation is a major threat for pragmatic trials in European countries.

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    authors: Ostuzzi G,Gastaldon C,Petrini C,Godman B,Barbui C

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    journal_title:Epidemiology and psychiatric sciences

    pub_type: 社论


    authors: Lin A,Nelson B,Yung AR

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  • Predictors and moderators of burden of care and emotional distress in first-episode psychosis caregivers: results from the GET UP pragmatic cluster randomised controlled trial.

    abstract:AIMS:First-episode psychosis (FEP) is a major life event and can have an adverse impact on the diagnosed individual and their families. The importance of intervening early and providing optimal treatments is widely acknowledged. In comparison to patient groups, literature is scarce on identifying treatment predictors a...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Onwumere J,Bonetto C,Lasalvia A,Miglietta E,Veronese A,Bellini F,Imbesi M,Bebbington P,Kuipers E,Ruggeri M,GET UP Group.

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  • Brain anatomy of autism spectrum disorders II. Focus on amygdala.

    abstract::This brief review encompasses the key findings of structural Magnetic Resonance Imaging (sMRI) research on amygdala volume in autism spectrum disorders (ASD). We also highlight the possible correlation between the autistic behavioural phenotype and amygdala alteration. ...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Bellani M,Calderoni S,Muratori F,Brambilla P

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    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Piccin S,Crippa A,Nobile M,Hardan AY,Brambilla P

    更新日期:2018-04-01 00:00:00

  • Trends in the prevalence and disability-adjusted life years of eating disorders from 1990 to 2017: results from the Global Burden of Disease Study 2017.

    abstract:AIM:Eating disorders have increasingly become a public health concern globally. This study aimed to reveal the burden of eating disorders at the global, regional and national levels using the Global Burden of Disease (GBD) Study 2017 data. METHODS:We extracted the age-standardised rates (ASRs) of prevalence and disabi...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Wu J,Liu J,Li S,Ma H,Wang Y

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  • Investigating 'place effects' on mental health: implications for population-based studies in psychiatry.

    abstract::Background. Interest in features of our local environments that may promote better mental health and wellbeing continues to rise among decision makers. Our purpose was to highlight a selection of these challenges and some promising avenues for enhancing the quality of evidence. Method. An analysis of approximately 267...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Astell-Burt T,Feng X

    更新日期:2015-02-01 00:00:00

  • Transitional care for young adults with ADHD: transforming potential upheaval into smooth progression.

    abstract::Increasing numbers of young adults need continued support for their attention deficit hyperactivity disorder (ADHD) beyond the age-boundary for children's services. The sparse literature on transition in general suggests patchy provision and huge gaps in transitional care, but also that young people with ADHD and othe...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Ford T

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  • In conversation with Massimiliano Gioni.

    abstract::Lately on these pages, a discussion is going on over the opportunity of the use of the definition 'outsider'. Especially in the USA, it is judged as demeaning, discriminating and inappropriate, whilst in Europe, it is used in a much more unconcerned way. Mr Gioni curator of numerous international exhibitions including...

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    pub_type: 传,历史文章,杂志文章


    authors: Tansella C

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  • Neuroscience and the future for mental health?

    abstract::Psychiatry is in one of its regular crises. It is a crisis of its diagnostic systems despite - perhaps because - of the recurrent claims about the extent of diagnosable 'brain disorders'. It is a crisis of its explanatory systems despite - perhaps because - of its current wager on the brain as the ultimate locus for e...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Rose N

    更新日期:2016-04-01 00:00:00

  • Diffusion imaging studies of white matter integrity in bipolar disorder.

    abstract::Diffusion tensor imaging (DTI) is a neuroimaging technique with a potential to elucidate white matter integrity. Recently, it has been used in the field of psychiatry to further understand the pathophysiology of major diseases, including bipolar disorder (BD). This review sought to focus on existing DTI findings on wh...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Bellani M,Brambilla P

    更新日期:2011-06-01 00:00:00

  • Mental health care in oncology. Contemporary perspective on the psychosocial burden of cancer and evidence-based interventions.

    abstract::With cancer incidence increasing over time worldwide, attention to the burden of psychiatric and psychosocial consequences of the disease is now mandatory for both cancer and mental health care professionals. Psychiatric disorders have been shown to affect at least 30-35% of cancer patients during all phases of the di...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Caruso R,Breitbart W

    更新日期:2020-01-09 00:00:00

  • Community psychiatry's achievements.

    abstract::Mental health care in the second half of the 20th century in much of the developed world has been dominated by the move out from large asylums. Both in response to this move and to make it possible, a pattern of care has evolved which is most commonly referred to as 'Community Psychiatry'. This narrative review descri...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Burns T

    更新日期:2014-12-01 00:00:00

  • Mistrust of mental health services: ethnicity, hospital admission and unfair treatment.

    abstract:AIMS:To explore the role of psychiatric admission, diagnosis and reported unfair treatment in the relationship between ethnicity and mistrust of mental health services. METHODS:The Mental Illness-Related Investigations on Discrimination (MIRIAD) study was a cross-sectional study of 202 individuals using secondary ment...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Henderson RC,Williams P,Gabbidon J,Farrelly S,Schauman O,Hatch S,Thornicroft G,Bhugra D,Clement S,MIRIAD study group.

    更新日期:2015-06-01 00:00:00

  • The CBCL 1.5-5 and the identification of preschoolers with autism in Italy.

    abstract:AIMS:To study the potential use of child behaviour checklist (CBCL) 1.5-5 scales for the early identification of preschoolers at risk of autism. METHODS:CBCL scores of three groups of preschoolers were compared: (1) an experimental group of 101 preschoolers with autism spectrum disorder (ASD); (2) a control group of 9...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Muratori F,Narzisi A,Tancredi R,Cosenza A,Calugi S,Saviozzi I,Santocchi E,Calderoni S

    更新日期:2011-12-01 00:00:00

  • Alzheimer's disease medication and outcomes of hospitalisation among patients with dementia.

    abstract:AIMS:The use of Alzheimer disease medication for the treatment of dementia symptoms has shown significant benefits with regards to functional and cognitive outcomes as well as nursing home placement (NHP) and mortality. Hospitalisations in these patient groups are characterised by extended length of stays (LOS), freque...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Möllers T,Perna L,Stocker H,Ihle P,Schubert I,Schöttker B,Frölich L,Bauer J,Brenner H

    更新日期:2019-11-14 00:00:00

  • Aligning the ICD-11 classification of disorders due to substance use with global service needs.

    abstract::The use of psychoactive, potentially dependence-producing substances is highly prevalent around the world, and contributes substantially to global disease burden. There is a major gap between the need for treatment for substance use disorders. Changes proposed for the classification of substance use disorders in the E...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Poznyak V,Reed GM,Medina-Mora ME

    更新日期:2018-06-01 00:00:00

  • A profile of Australian mental health carers, their caring role and service needs: results from the 2012 Survey of Disability, Ageing and Carers.

    abstract:AIMS:Planning mental health carer services requires information about the number of carers, their characteristics, service use and unmet support needs. Available Australian estimates vary widely due to different definitions of mental illness and the types of carers included. This study aimed to provide a detailed profi...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Diminic S,Hielscher E,Harris MG,Lee YY,Kealton J,Whiteford HA

    更新日期:2019-12-01 00:00:00

  • The nature and correlates of paid and unpaid work among service users of London Community Mental Health Teams.

    abstract::Aims. Little is known about how the rates and characteristics of mental health service users in unpaid work, training and study compare with those in paid employment. Methods. From staff report and patient records, 1353 mental health service users of seven Community Mental Health Teams in two London boroughs were cate...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: Lloyd-Evans B,Marwaha S,Burns T,Secker J,Latimer E,Blizard R,Killaspy H,Totman J,Tanskanen S,Johnson S

    更新日期:2013-06-01 00:00:00

  • Making mental health an integral part of sustainable development: the contribution of a social determinants framework.

    abstract::There have been repeated calls to include mental health in the sustainable development goals (SDGs), arguing that progress in development will not be made without improvements in mental health. Although these calls are starting to gain political traction, currently only a tiny fraction of international development wor...

    journal_title:Epidemiology and psychiatric sciences

    pub_type: 杂志文章


    authors: De Silva MJ

    更新日期:2015-04-01 00:00:00