Suppression of phase separation and giant enhancement of superconducting transition temperature in FeSe(1-x)Te(x) thin films.

abstract：:[3H]Puromycin and N-(ethyl-2-diazomalonyl)[3H]puromycin are incorporated into E. coli ribosomes on irradiation at 253.7 nm. Both compounds incorporate into both protein and nucleic acid. Two-dimensional gel electrophoresis of ribosomal protein shows that L23 is the major protein labeled by puromycin. Although incorpor...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Cooperman BS,Jaynes EN,Brunswick DJ,Luddy MA

更新日期：1975-08-01 00:00:00

abstract：:The recent development of HIV-1 lentiviral vectors is especially useful for gene transfer because they achieve efficient integration into nondividing cell genomes and successful long-term expression of the transgene. These attributes make the vector useful for gene delivery, mutagenesis, and other applications in mamm...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Lai Z,Han I,Park M,Brady RO

更新日期：2002-03-19 00:00:00

abstract：:By harnessing the oxidative power of microorganisms, energy can be recovered from reservoirs of less-concentrated organic matter, such as marine sediment, wastewater, and waste biomass. Left unmanaged, these reservoirs can become eutrophic dead zones and sites of greenhouse gas generation. Here, we introduce a unique ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Xie X,Ye M,Hsu PC,Liu N,Criddle CS,Cui Y

更新日期：2013-10-01 00:00:00

abstract：:T helper (Th) lymphocytes can develop memory for the expression of particular cytokines, like IL-4 or IL-10, in that reexpression of those cytokines is independent of the original costimulatory signal IL-4 and depends only on T cell receptor stimulation. Here, we show that in the course of Th2 cell differentiation in ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Löhning M,Richter A,Stamm T,Hu-Li J,Assenmacher M,Paul WE,Radbruch A

更新日期：2003-10-14 00:00:00

abstract：:Kinesin-1 is a molecular motor protein that transports cargo along microtubules. Inside cells, the vast majority of kinesin-1 is regulated to conserve ATP and to ensure its proper intracellular distribution and coordination with other molecular motors. Regulated kinesin-1 folds in half at a hinge in its coiled-coil st...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Dietrich KA,Sindelar CV,Brewer PD,Downing KH,Cremo CR,Rice SE

更新日期：2008-07-01 00:00:00

abstract：:The redox potentials of electron transfer proteins vary over a wide range, even when the type of redox center is the same. Rees [Proc. Natl. Acad. Sci. USA (1985) 82, 3082-3085] proposed that this variation of redox potential partly reflects the different net charges of the proteins, and he presented a linear correlat...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Moore GR,Pettigrew GW,Rogers NK

更新日期：1986-07-01 00:00:00

abstract：:Expression of alphavbeta3- or alphavbeta5-integrins and selectins is widespread on blood cells and endothelial cells. Here we report that human tumor cells injected s.c. into mice lacking beta3- or beta3/beta5-integrins or various selectins show enhanced tumor growth compared with growth in control mice. There was inc...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Taverna D,Moher H,Crowley D,Borsig L,Varki A,Hynes RO

更新日期：2004-01-20 00:00:00

abstract：:Differences between early and late passage cell cultures on the organelle and macromolecular levels have been attributed to cellular "aging". However, concern has been expressed over whether changes in diploid cell populations after serial passage in vitro accurately reflect human cellular aging in vivo. Studies were ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Schneider EL,Mitsui Y

更新日期：1976-10-01 00:00:00

abstract：:Myosins play countless critical roles in the cell, each requiring it to be activated at a specific location and time. To control myosin VI with this specificity, we created an optogenetic tool for activating myosin VI by fusing the light-sensitive Avena sativa phototropin1 LOV2 domain to a peptide from Dab2 (LOVDab), ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： French AR,Sosnick TR,Rock RS

更新日期：2017-02-28 00:00:00

abstract：:Spreading depression (SD), a slow diffusion-mediated self-sustained wave of depolarization that severely disrupts neuronal function, has been implicated as a cause of cellular injury in a number of central nervous system pathologies, including blind spots in the retina. Here we show that in the hypoglycemic chicken re...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Yu Y,Santos LM,Mattiace LA,Costa ML,Ferreira LC,Benabou K,Kim AH,Abrahams J,Bennett MV,Rozental R

更新日期：2012-02-14 00:00:00

abstract：:Recombinant techniques allow one to engineer an antibody molecule and, in this way, manipulate its properties and functions. We engineered a chimeric human/mouse antibody to the tumor-associated antigen ganglioside GD2, with the aim of decreasing its serum half-life, maintaining its full antigen-binding capacity, and ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Mueller BM,Reisfeld RA,Gillies SD

更新日期：1990-08-01 00:00:00

abstract：:Protein tyrosine phosphorylation in purified synaptic vesicles from rat forebrain has been studied in the presence of Mn2+ and orthovanadate. High levels of endogenous protein tyrosine phosphorylation were observed. Four major phosphoproteins, with apparent molecular masses of 105, 94, 38, and 30 kDa, were shown to co...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Pang DT,Wang JK,Valtorta F,Benfenati F,Greengard P

更新日期：1988-02-01 00:00:00

abstract：:Engagement of high-affinity IgE receptors leads to activation of tyrosine and serine/threonine kinases and the immediate phosphorylation of receptor beta (serine and tyrosine) and gamma (threonine and tyrosine) chains. Receptor disengagement leads to dephosphorylation of beta and gamma chains via the action of undefin...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Paolini R,Numerof R,Kinet JP

更新日期：1992-11-15 00:00:00

abstract：:Starburst polyamidoamine dendrimers are a new class of synthetic polymers with unique structural and physical characteristics. These polymers were investigated for the ability to bind DNA and enhance DNA transfer and expression in a variety of mammalian cell lines. Twenty different types of polyamidoamine dendrimers w...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Kukowska-Latallo JF,Bielinska AU,Johnson J,Spindler R,Tomalia DA,Baker JR Jr

更新日期：1996-05-14 00:00:00

abstract：:The rates of reassociation of DNA from a monkey cell line (Vero), from SV40 pseudovirus (consisting of Vero DNA and virus protein coat), and from mature SV40 were measured. The results show that the host DNA in the pseudovirus contains repeated and unique sequences in the same proportions as normal host DNA; hence, no...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Grady L,Axelrod D,Trilling D

更新日期：1970-12-01 00:00:00

abstract：:The 89-kDa cell surface glycoprotein, P3.58, is detectable on advanced human melanomas in situ but not on benign melanocytes or early melanomas. cDNA cloning of P3.58 from melanoma cells was accomplished by screening a lambda zap expression vector library with monoclonal antibodies produced against the denatured antig...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Johnson JP,Stade BG,Holzmann B,Schwäble W,Riethmüller G

更新日期：1989-01-01 00:00:00

abstract：:In this report we examine the effects of chronic anaerobic exposure and subsequent reoxygenation on protein synthesis patterns in Chinese hamster ovary cells. It is observed by two-dimensional gel electrophoresis (isoelectric focusing/NaDodSO4/PAGE) that the transition from an atmospheric environment to an anaerobic s...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Sciandra JJ,Subjeck JR,Hughes CS

更新日期：1984-08-01 00:00:00

abstract：:Transcription initiation is a dynamic process in which RNA polymerase (RNAP) and promoter DNA act as partners, changing in response to one another, to produce a polymerase/promoter open complex (RPo) competent for transcription. In Escherichia coli RNAP, region 1.1, the N-terminal 100 residues of sigma(70), is thought...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Hook-Barnard IG,Hinton DM

更新日期：2009-01-20 00:00:00

abstract：:Fe(CN)6(-3) oxidation of the aerobically isolated 7Fe Azotobacter vinelandii ferredoxin I, (7Fe)FdI, is a degradative reaction. Destruction of the [4Fe-4S] cluster occurs first, followed by destruction of the [3Fe-3S] cluster. At a Fe(CN)6(-3)/(7Fe)FdI concentration ratio of 20, the product is a mixture of apoprotein ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Stephens PJ,Morgan TV,Devlin F,Penner-Hahn JE,Hodgson KO,Scott RA,Stout CD,Burgess BK

更新日期：1985-09-01 00:00:00

abstract：:Focal adhesion kinase (FAK) is a nonreceptor tyrosine kinase involved in development and human disease, including cancer. It is currently thought that the four-point one, ezrin, radixin, moesin (FERM)-kinase domain linker, which contains autophosphorylation site tyrosine (Y) 397, is not required for in vivo FAK functi...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Heim JB,Squirewell EJ,Neu A,Zocher G,Sominidi-Damodaran S,Wyles SP,Nikolova E,Behrendt N,Saunte DM,Lock-Andersen J,Gaonkar KS,Yan H,Sarkaria JN,Krendel M,van Deursen J,Sprangers R,Stehle T,Böttcher RT,Lee JH,Ordog T

更新日期：2017-04-11 00:00:00

abstract：:The α-proteobacterium Sinorhizobium meliloti establishes a chronic intracellular infection during the symbiosis with its legume hosts. Within specialized host cells, S. meliloti differentiates into highly polyploid, enlarged nitrogen-fixing bacteroids. This differentiation is driven by host cells through the productio...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Penterman J,Abo RP,De Nisco NJ,Arnold MF,Longhi R,Zanda M,Walker GC

更新日期：2014-03-04 00:00:00

abstract：:Many cellular cargoes move bidirectionally along microtubules, driven by teams of plus- and minus-end-directed motor proteins. To probe the forces exerted on cargoes during intracellular transport, we examined latex beads phagocytosed into living mammalian macrophages. These latex bead compartments (LBCs) are encased ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Hendricks AG,Holzbaur EL,Goldman YE

更新日期：2012-11-06 00:00:00

abstract：:A pluripotent cell line, C3H10T1/2, is induced to undergo adipogenesis by a mixture of factors that includes a glucocorticoid such as dexamethasone. We found that expression of myostatin (MSTN), a TGF-beta family member extensively studied in muscle, was induced by dexamethasone under those differentiation conditions....

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Feldman BJ,Streeper RS,Farese RV Jr,Yamamoto KR

更新日期：2006-10-17 00:00:00

abstract：:We sequenced the genome of Saccharomyces cerevisiae strain YJM789, which was derived from a yeast isolated from the lung of an AIDS patient with pneumonia. The strain is used for studies of fungal infections and quantitative genetics because of its extensive phenotypic differences to the laboratory reference strain, i...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Wei W,McCusker JH,Hyman RW,Jones T,Ning Y,Cao Z,Gu Z,Bruno D,Miranda M,Nguyen M,Wilhelmy J,Komp C,Tamse R,Wang X,Jia P,Luedi P,Oefner PJ,David L,Dietrich FS,Li Y,Davis RW,Steinmetz LM

更新日期：2007-07-31 00:00:00

abstract：:The HIV type 1 (HIV-1) virion infectivity factor (Vif) protein blocks the action of the host defense factor APOBEC3G in human cells, thereby allowing release of infectious virions, but fails to inhibit similar APOBEC3G proteins present in some simian cells. Conversely, the Vif protein encoded by the African green monk...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Bogerd HP,Doehle BP,Wiegand HL,Cullen BR

更新日期：2004-03-16 00:00:00

abstract：:There is increasing, but largely indirect, evidence pointing to an effect of commensal gut microbiota on the central nervous system (CNS). However, it is unknown whether lactic acid bacteria such as Lactobacillus rhamnosus could have a direct effect on neurotransmitter receptors in the CNS in normal, healthy animals. ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Bravo JA,Forsythe P,Chew MV,Escaravage E,Savignac HM,Dinan TG,Bienenstock J,Cryan JF

更新日期：2011-09-20 00:00:00

abstract：:In all photosynthetic organisms, light energy is used to drive electrons from a donor chlorophyll species via a series of acceptors across a biological membrane. These light-induced electron-transfer processes display a remarkably high quantum efficiency, indicating a near-complete inhibition of unproductive charge re...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Makita H,Hastings G

更新日期：2017-08-29 00:00:00

abstract：:The human genome is made up of long DNA segments, the isochores, which are compositionally homogeneous and can be subdivided into a small number of families characterized by different G+C levels. Chromosome in situ suppression hybridization (in which excess unlabeled human DNA is added to suppress hybridization of rep...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Saccone S,De Sario A,Wiegant J,Raap AK,Della Valle G,Bernardi G

更新日期：1993-12-15 00:00:00

abstract：:Metastatic colorectal cancer (mCRC) patients have poor overall survival despite using irinotecan- or oxaliplatin-based chemotherapy combined with anti-EGFR (epidermal growth factor receptor) drugs, especially those with the oncogene mutation of KRAS Metformin has been reported as a potentially novel antitumor agent in...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Xie J,Xia L,Xiang W,He W,Yin H,Wang F,Gao T,Qi W,Yang Z,Yang X,Zhou T,Gao G

更新日期：2020-06-09 00:00:00

abstract：:The mammalian protein ZnT3 resides on synaptic vesicle membranes of zinc-containing neurons, suggesting its possible role in vesicular zinc transport. We show here that histochemically reactive zinc, corresponding to the zinc found within synaptic vesicles, was undetectable in the brains of mice with targeted disrupti...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Cole TB,Wenzel HJ,Kafer KE,Schwartzkroin PA,Palmiter RD

更新日期：1999-02-16 00:00:00