Abstract:
AIM:The study was carried out on elderly nursing home residents in Taiwan. We assessed whether the serial QuantiFERON-TB Gold (QFT-G) assay and serial tuberculin skin test (TST) were reliable tools to predict or exclude the development of active tuberculosis (TB). METHODS:This prospective observational cohort study involved non-bacillus Calmette-Guérin-vaccinated 259 elderly nursing home residents free of active TB at baseline. Of these, 147 were eligible for follow up. Participants underwent serial QFT-G and TST at baseline and 2-year follow up, and were monitored for active TB over 5 years. Agreement between QFT-G and TST, incidence rate ratio, positive predictive value, and negative predictive value for progression to active TB were measured. RESULTS:During 5-year follow up, three participants developed active TB. The agreement between these two tests was 54.13% (ĸ = 0.167, P = 0.001). The incidence rate ratio was 15.8 (P = 0.016) for the QFT-G-conversion group compared with the TST-positive group at baseline. Positive predictive value for QFT-G conversion groups was 25%. Negative predictive value was 100% for the TST-negative group at baseline. CONCLUSION:In the elderly nursing home residents, QFT-G conversion is a more reliable tool to predict the development of active TB. Meanwhile, TST is a valuable tool for predicting the chance of not developing active TB.
journal_name
Geriatr Gerontol Intjournal_title
Geriatrics & gerontology internationalauthors
Tsou PH,Huang WC,Huang CC,Lin CF,Wu KM,Hsu JY,Shen GHdoi
10.1111/ggi.12416subject
Has Abstractpub_date
2015-10-01 00:00:00pages
1179-84issue
10eissn
1444-1586issn
1447-0594journal_volume
15pub_type
杂志文章abstract:AIM:To investigate the frequency of calcification in the basal ganglia and the dentate nuclei in the cerebellum, and compare the difference in age and area, we examined the brain computed tomography (CT) images of all patients in two representative university hospitals in Japan. METHODS:We examined the brain CT images...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12004
更新日期:2013-07-01 00:00:00
abstract:AIM:This study aimed to assess the relationship between functional limitations and depression among community-dwelling older adults in Malaysia. METHODS:Data from a nation-wide community-based cross-sectional study were analyzed. This study was conducted using a two-stage stratified random sampling design. In total, 3...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.14012
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Geriatricians are physicians who work primarily with the elderly and deal with diseases that often accompany old age, such as Alzheimer's disease. In the last few years, data from questionnaires have demonstrated increasing criticism of geriatricians regarding their working conditions in geriatric medicine. ...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1447-0594.2011.00714.x
更新日期:2012-01-01 00:00:00
abstract:AIM:Increases in oxidative stress and advanced glycation end-products (AGE) formation play an important role in the pathogenesis of aging. Carnosine (CAR; β-alanyl-L-histidine) has anti-oxidant and antiglycating properties. We investigated the effect of CAR supplementation on AGE levels, and protein and lipid oxidation...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13126
更新日期:2017-12-01 00:00:00
abstract:AIM:Home medical care for older adults with chronic conditions is becoming an increasing important issue in Japan. We need to support long-term medical care at home and avoid unplanned hospitalizations, which can adversely affect activities of daily living and quality of life. In this study, we investigated whether swa...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13753
更新日期:2019-10-01 00:00:00
abstract:AIM:To validate and standardize the Brazilian version of the Medication Regimen Complexity Index (MRCI) for older adults in primary healthcare. METHODS:A cross-sectional methodological study was carried out with elderly patients attending primary healthcare centers in southeastern Brazil. Convergent validity was teste...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13261
更新日期:2018-06-01 00:00:00
abstract:AIM:There is a high prevalence of combined peripheral and coronary artery disease, with increasing morbidity and decline in cardiac function. The aim of the present study was to find an association between ankle brachial index, a non-invasive measure of peripheral artery disease, and ejection fraction in elderly patien...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12232
更新日期:2015-04-01 00:00:00
abstract:AIM:Musculoskeletal degenerative disease (MSD; osteoporosis, knee arthritis and lumbar spondylosis) decreases the quality of life (QOL) of older people. The objective of the present study was to identify the factors related to the absence of MSD in multivariate logistic regression analysis. METHODS:The participants we...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13786
更新日期:2019-11-01 00:00:00
abstract:AIM:To examine the association of physical exercise (PE) and medication on cognitive function in older adults with vascular risk. METHODS:This was a cross-sectional study of 478 non-demented participants aged ≥60 years with vascular risk. Management strategy included PE (mind-body exercise and/or strenuous exercise), ...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.14048
更新日期:2020-11-01 00:00:00
abstract:AIM:In the present study, we analyzed the severity of white matter hyperintensities detected on magnetic resonance imaging of the brain in older Japanese adults who were aged in their mid 80s, and examined its relationships with the clinical parameters. METHODS:To identify factors related to the severity of white matt...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12671
更新日期:2015-12-01 00:00:00
abstract::The imbalance between cholinergic activity and dopaminergic activity in the striatum causes a variety of neurological disorders, such as Parkinson's disease. During sensorimotor learning, the arrival of a conditioned stimulus reporting a reward evokes a pause response in the firing of the tonically active cholinergic ...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章,评审
doi:10.1111/j.1447-0594.2010.00588.x
更新日期:2010-07-01 00:00:00
abstract:AIM:The aim of the present study was to examine whether behavioral and psychological symptoms of dementia at the time of admission could be a predictor of falls in older people with dementia residing in geriatric health service facilities. METHODS:Three geriatric health services facilities located in Fukushima Prefect...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13528
更新日期:2018-11-01 00:00:00
abstract:AIM:Population aging is a global phenomenon, and East Asian countries are no exception. However, the use of advance care planning (ACP) and advance directives (ADs) are not widespread in East Asia. This study aimed to examine the awareness of ACP/ADs and its related factors among community-dwelling older persons in Jap...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.14086
更新日期:2021-01-01 00:00:00
abstract:AIM:As the Japanese population ages, the number of older patients with chronic obstructive pulmonary disease (COPD) is expected to increase, but the prevalence of COPD in patients aged ≥80 years remains unclear. The purpose of the present study was to determine the prevalence of COPD in independent community-dwelling o...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13091
更新日期:2017-12-01 00:00:00
abstract:AIM:Previous studies on health transition have focused on single-dimension outcomes and minimally evaluated heterogeneity. This study aimed to explore heterogeneous and multidimensional health-transition patterns on comorbidity, frailty and disability while examining the factors predicting different patterns of health ...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/j.1447-0594.2012.00937.x
更新日期:2013-07-01 00:00:00
abstract:AIM:This cross-sectional study examined whether sleep duration and excessive daytime sleepiness (EDS) were associated with social frailty in community-dwelling older people. METHODS:A total of 4427 community-dwelling older people (51.4% women, mean age 71.9 years) who met the entry criteria were included in this study...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13734
更新日期:2019-09-01 00:00:00
abstract:AIM:To examine the efficacy of rehabilitation for elderly individuals with dementia at intermediate facilities between hospitals and home, based on the policies for elderly individuals to promote community-based care at home and dehospitalization. METHODS:Participants were older adults with dementia newly admitted to ...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章,多中心研究
doi:10.1111/ggi.12080
更新日期:2014-01-01 00:00:00
abstract:AIM:Low alanine aminotransferase (ALT) level is associated with frailty in the older adult population. We investigated the usefulness of ALT in predicting low muscle strength among older patients with diabetes. METHODS:We included 550 men aged ≥50 years and 525 postmenopausal women. All participants had diabetes, and ...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13868
更新日期:2020-04-01 00:00:00
abstract:AIM:Nutrition is the focus of a new treatment target in older hospitalized cardiac patients. However, little is known about the differences in nutritional status in relation to physical performance in these inpatients. We determined the differences in physical performance based on the Geriatric Nutritional Risk Index (...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12257
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the intensity of pain and levels of disability at different times through the day in patients with burning mouth syndrome (BMS) over a 14-day period. METHODS:This was a prospective clinical study of 30 patients with BMS, 26 of whom completed the study. The parameters studied were pain intensity (...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12303
更新日期:2015-04-01 00:00:00
abstract:AIM:Secondary necrotic cells generated in vivo induce inflammatory responses; for example, the production of macrophage inflammatory protein-2 (MIP-2) and subsequent infiltration of neutrophils. The aim of the present study was to elucidate the effect of aging on the phagocytosis of secondary necrotic cells and the inf...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12436
更新日期:2016-01-01 00:00:00
abstract:AIM:The aim of the present study was to develop a risk assessment scale for predicting incident functional disability among older adults. METHODS:We used prospective cohort data from the Japan Gerontological Evaluation Study, a nationwide survey of 90 889 functionally independent older people collected from 23 municip...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13503
更新日期:2018-10-01 00:00:00
abstract::A series of our studies on the development of the Dementia Assessment Sheet for Community-based Integrated Care System 21-items (DASC-21) were reviewed. Study 1: to examine the distribution of scores and internal reliability of DASC-21, trained nurses and researchers visited the homes of 1341 participants aged 65 year...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章,评审
doi:10.1111/ggi.12727
更新日期:2016-03-01 00:00:00
abstract:AIM:Frailty and sarcopenia affect the prognosis and quality of life of patients with chronic obstructive pulmonary disease (COPD). However, it remains uncertain which model is the most suitable for evaluating vulnerability in patients with COPD. We evaluated the validity of three frailty models - the Kihon Checklist (K...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13740
更新日期:2019-09-01 00:00:00
abstract:AIM:Sensitive, specific neuropsychological screening tests, such as the Addenbrooke's Cognitive Examination Revised (ACE-R), are essential for dementia diagnosis. We aimed to validate the use of the Korean version of ACE-R (K-ACER) to differentiate Alzheimer's disease (AD) from subcortical ischemic vascular dementia (S...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/j.1447-0594.2010.00624.x
更新日期:2010-10-01 00:00:00
abstract:AIM:We investigated factors that predict the prognosis of activities of daily living (ADL) in elderly patients who had undergone rehabilitation during hospitalization for acute infectious disease. METHODS:The present prospective cohort study included 131 patients who were hospitalized due to acute infectious disease a...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13227
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:Health-related quality of life (HRQOL) in older adults is determined by personal conditions, as well as by the social and physical environment. The purpose of the present study was to describe the factors related to health conditions and residential environment that influence HRQOL of older adults. METHODS:...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12325
更新日期:2015-05-01 00:00:00
abstract:AIM:The study aimed to study the prevalence, etiologies, clinical profile and outcome of delirium in hospitalized elderly in medicine wards. METHODS: Four hundred elderly patients of more than 60years of age admitted with delirium in the emergency and medicine wards of Sir Sunderlal Hospital Varanasi, India, were eva...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/j.1447-0594.2011.00710.x
更新日期:2011-10-01 00:00:00
abstract:AIMS:Few studies have been published on the use of the Cambridge Cognitive Examination Test - Revised (CAMCOG-R) for cognitive assessment of low educational level older adults. The aim of the present study was to determine the accuracy of the Brazilian version of the CAMCOG-R (Br-CAMCOG-R) within a sample of low educat...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12161
更新日期:2014-10-01 00:00:00
abstract:AIM:We propose a simple method to measure knee extensor muscle strength using a single-legged vertical squat. The purpose of the present study was to assess the validity of this method in comparison with standard methods of measurement. METHODS:A total of 30 healthy adults (mean age 22 years) and 28 healthy older indi...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13299
更新日期:2018-07-01 00:00:00