Abstract:
AIM:To examine the efficacy of rehabilitation for elderly individuals with dementia at intermediate facilities between hospitals and home, based on the policies for elderly individuals to promote community-based care at home and dehospitalization. METHODS:Participants were older adults with dementia newly admitted to intermediate facilities. A total of 158 in the intervention group who claimed Long-Term Care Insurance for three consecutive months, and 54 in the control group were included in the analysis. The interventions were carried out in a tailor-made manner to meet individual needs. The personal sessions were carried out three times a week for 3 months after admission by physical, occupational or speech therapists. Outcome measures were cognitive tests (Hasegawa Dementia Scale revised [HDS-R] and Mini-Mental State Examination), and observational assessments of dementia severity, activities of daily living (ADL), social activities, behavioral and psychological symptoms of dementia (BPSD) using a short version of the Dementia Disturbance Scale (DBD13), depressive mood, and vitality. RESULTS:Significant improvement in the intervention group was shown in cognitive function measured by HDS-R (interaction F[1, 196] = 5.190, P = 0.024), observational evaluation of dementia severity (F[1,198] = 9.550, P = 0.002) and BPSD (DBD13; F[1,197] = 4.506, P = 0.035). Vitality, social activities, depressive mood and ADL were significantly improved only in the intervention group, although interaction was not significant. CONCLUSIONS:Significant improvement by intervention was shown in multiple domains including cognitive function and BPSD. Cognitive decline and worsening of BPSD are predictors of care burden and hospitalization, thus intensive rehabilitation for dementia was beneficial for both individuals with dementia and their caregivers.
journal_name
Geriatr Gerontol Intjournal_title
Geriatrics & gerontology internationalauthors
Toba K,Nakamura Y,Endo H,Okochi J,Tanaka Y,Inaniwa C,Takahashi A,Tsunoda N,Higashi K,Hirai M,Hirakawa H,Yamada S,Maki Y,Yamaguchi T,Yamaguchi Hdoi
10.1111/ggi.12080subject
Has Abstractpub_date
2014-01-01 00:00:00pages
206-11issue
1eissn
1444-1586issn
1447-0594journal_volume
14pub_type
杂志文章,多中心研究abstract:AIM:To evaluate the safety, tolerability and pharmacokinetic profile of bapineuzumab after a single intravenous injection in Japanese patients with mild to moderate Alzheimer's disease. METHODS:Participants received either a placebo (n = 8), or bapineuzumab 0.15 (n = 6), 0.5 (n = 6), 1.0 (n = 6) or 2.0 (n = 6) mg/kg. ...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/ggi.12516
更新日期:2016-05-01 00:00:00
abstract:AIM:Smart bracelets are popular today. Based on their built-in motion sensors, they can serve as a cost-effective method of gait assessment in home-based care. Few studies have applied smart bracelets in the gait assessment of older Chinese adults. The present study aimed to: (i) establish reference gait parameters of ...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13492
更新日期:2018-09-01 00:00:00
abstract:AIM:The present study investigated the status of potentially harmful drug-drug interactions (PHDI) in older adults, to obtain insight into factors that influence the risk of PHDI. METHODS:The present study included Korean people aged ≥65 years who were prescribed one or more drugs included in the list of PHDI under th...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13495
更新日期:2018-09-01 00:00:00
abstract::Alzheimer's disease, an affliction of old age, is one of the leading causes for dementia worldwide. Various risk factors including family history, genetics and infections have been implicated in its pathogenesis. The cognitive decline in this condition is mainly a result of the formation of amyloid deposits that provo...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章,评审
doi:10.1111/ggi.12425
更新日期:2015-04-01 00:00:00
abstract:AIM:In view of the paucity of data on the quality of life (QOL) in Chinese Alzheimer's disease (AD) patients, we investigated the effects of cognitive function and depressive mood on QOL among our Chinese AD patients in Hong Kong, using the Cantonese Chinese version of Quality of Life in Alzheimer's disease (QOL-AD). ...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/j.1447-0594.2010.00643.x
更新日期:2011-01-01 00:00:00
abstract:AIMS:The aim of the present study was to evaluate whether there was an inflammation-mediated link between Alzheimer's disease (AD) and type 2 diabetes mellitus (DM) status. METHODS:An age-matched control group and patient groups designated as AD without treatment (AD); AD under cholinesterase inhibitors (AD-CEI); DM w...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12602
更新日期:2016-10-01 00:00:00
abstract:AIM:Depression affecting caregivers is a risk factor for discontinuing at-home care. The present cross-sectional study was conducted to evaluate factors related to depression among family caregivers. METHODS:A cross-sectional study was conducted to evaluate factors related to depression among family caregivers of the ...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/j.1447-0594.2011.00754.x
更新日期:2012-04-01 00:00:00
abstract:AIM:The health and well-being of older adults are closely related to their economic and living statuses. Socioeconomic inequality has a substantial impact on the healthcare received by these older adults. The present study aimed to understand the current economic and living statuses of community older adults, and exami...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12875
更新日期:2017-10-01 00:00:00
abstract:AIM:To estimate the prevalence of diabetes, heart disease, hypertension and stroke in self-report and hospital data in two cohorts of women; measure sensitivity and agreement between data sources; and compare between cohorts. METHODS:Women born between 1946-1951 and 1921-1926 who participated in the Australian Longitu...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12442
更新日期:2016-01-01 00:00:00
abstract:AIM:This study analyzed the trend of gender gaps in life expectancy (GGLE) in Japan between 1947 and 2010, and explored the correlations of GGLE with gender mortality ratio and social development indices. METHODS:Using GGLE and social indices data collected from the official websites, we carried out trends analysis of...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12001
更新日期:2013-07-01 00:00:00
abstract:AIM:To evaluate the effect of oral disorders on the quality of life of older adults. METHODS:A cross-sectional study of older adults (aged ≥ 60 years) who reside in a small Brazilian city was carried out. Trained and calibrated academics and dentists collected the data. The analyses carried out were descriptive, univa...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12489
更新日期:2016-04-01 00:00:00
abstract:AIM:Sarcopenia causes a decline in physical performance and decreased quality of life. However, there is little evidence for effective treatments. Because of the similarities between osteoporosis and sarcopenia, alfacalcidol used for osteoporosis might be beneficial for low muscle mass. Therefore, we investigated the e...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12222
更新日期:2014-02-01 00:00:00
abstract:AIM:Single photon emission computed tomography (SPECT) studies showed that regional cerebral blood flow (rCBF) abnormalities in idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD) are similar to those seen in Parkinson's disease (PD) and dementia with Lewy bodies (DLB). The aim of the present study was t...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12068
更新日期:2014-01-01 00:00:00
abstract:AIM:Malnutrition is common in older patients and is associated with adverse outcomes. The Geriatric Nutritional Risk Index (GNRI) has been developed as an objective index to assess nutritional risk in these patients. However, there is limited evidence regarding the association between GNRI and postoperative delirium (P...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13963
更新日期:2020-08-01 00:00:00
abstract:AIM:Family function is an essential factor affecting older adults' health. However, there has been no appropriate method to assess the family function of most older adults with fragility or poor health status. The present study aimed to explore the differences and relevance of family function estimated by home care nur...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12544
更新日期:2016-06-01 00:00:00
abstract:AIM:To investigate the prevalence and burden (combination of number and severity) of vertebral fractures in men and women with hip fracture. METHODS:We investigated 458 of 490 hip-fracture patients admitted consecutively to a rehabilitation hospital. Lateral radiographs of the spine were taken 19.2 ± 5.5 days (mean ± ...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12479
更新日期:2016-03-01 00:00:00
abstract:AIMS:We aimed to investigate whether older age leads to limitations in the starting dose of imatinib in daily treatment of chronic myeloid leukemia, and to determine the compliance of elderly patients with tyrosine kinase inhibitors (TKI) therapy. METHODS:Data including the clinical characteristics, therapeutic outcom...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章,多中心研究
doi:10.1111/ggi.12341
更新日期:2015-06-01 00:00:00
abstract:AIM:The National Health and Nutrition Survey, Japan, has annually monitored two indicators of physical activity in adults. They are contrasting in the association with age; the prevalence of exercise habit is lower and step counts are higher among younger participants. The present study aimed to examine the effects of ...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12956
更新日期:2017-10-01 00:00:00
abstract:AIM:Alzheimer's disease (AD) is the most common neurodegenerative disease. In 2000, Mendiondo et al. reported on a model predicting that AD progresses at an accelerating rate and cognitive function worsens rapidly. Recently, anti-AD drugs and non-pharmacological intervention have been established, but the effect of int...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13883
更新日期:2020-04-01 00:00:00
abstract:AIM:The prevalence of constipation and prevalence of pollakisuria among older patients receiving home medical care have not been reported, and risk factors for these symptoms are not clear in this setting. The present study sought to determine the prevalence and risk factors of constipation and pollakisuria among older...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13610
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:Long-term care (LTC) insurance was introduced in Japan in 2000. Herein, we describe the trends in demand for LTC, using age-standardized and level-specific rates of entitlement and utilization of LTC at national and prefectural levels. METHODS:We analyzed LTC data from 2002-2005 to examine: (i) the influenc...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/j.1447-0594.2008.00466.x
更新日期:2008-09-01 00:00:00
abstract:AIMS:Inflammatory processes might play a significant role at the pathophysiology of Alzheimer's disease (AD). Neuroinflammation is characterized by activation of microglia and the release of inflammatory cytokines, such as interleukin (IL)-1β, IL-6 and tumor necrosis factor-α. Although, it is unknown what the real cont...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12704
更新日期:2017-02-01 00:00:00
abstract:AIM:Aging shifts body composition to comprising more fat and less muscle. Sarcopenia, particularly in the knee extensors, and obesity, particularly visceral obesity, either alone or in combination, may exacerbate age-related physical disability. We investigated the association between age-related quadriceps (Qc) sarcop...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/j.1447-0594.2010.00610.x
更新日期:2010-07-01 00:00:00
abstract:AIM:Postoperative cognitive dysfunction is often observed in older patients. Previous reports described the link between postoperative cognitive dysfunction and general anesthetics, such as sevoflurane, but the exact mechanism remains unclear. We therefore sought to characterize the effects of sevoflurane on hippocampa...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13619
更新日期:2019-04-01 00:00:00
abstract::A series of our studies on the development of the Dementia Assessment Sheet for Community-based Integrated Care System 21-items (DASC-21) were reviewed. Study 1: to examine the distribution of scores and internal reliability of DASC-21, trained nurses and researchers visited the homes of 1341 participants aged 65 year...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章,评审
doi:10.1111/ggi.12727
更新日期:2016-03-01 00:00:00
abstract:AIM:The Community Commitment Scale was developed in Japan to measure communities' ability to prevent older adults' social isolation, including socializing and belonging in the community. We translated the scale into Korean (the Community Commitment Scale-Korean version [CCS-K]), and determined its internal consistency,...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13249
更新日期:2018-05-01 00:00:00
abstract:AIM:To identify the association between different living arrangements of intergenerational household composition and depression in older adults. METHODS:Data from the Korea Longitudinal Study of Aging, the first to fourth waves, were used. Using the first wave as baseline, our analysis included 5046 participants aged ...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13066
更新日期:2017-12-01 00:00:00
abstract:AIM:To determine whether answering three questions erroneously ("what is the date today?," "when were you born?" and "how old are you?") allows for the detection of advanced cognitive impairment in polypathological patients. METHODS:A cross-sectional study of patients admitted to the internal medicine and geriatrics d...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13204
更新日期:2018-03-01 00:00:00
abstract:AIM:We studied the association between age and survival after stroke. We particularly focused on deaths that could be attributed to the stroke lesion itself; that is, early death in severe stroke. METHODS:A registry of all hospitalized stroke patients in Denmark included 93897 patients with information on stroke sever...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章,多中心研究
doi:10.1111/ggi.12165
更新日期:2014-10-01 00:00:00
abstract::Now that the number of elderly people has increased and the number of dementia patients is rapidly increasing, dementia might be regarded as a common disease. Under these circumstances, the establishment of systems to support the elderly with dementia from the early stages, and to provide primary care doctors and care...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章,评审
doi:10.1111/ggi.12248
更新日期:2014-04-01 00:00:00