Alteration of brain glycoproteins during aging.

abstract：AIM:The association between polypharmacy and the development of frailty is unknown. The present study assessed the longitudinal relationship between polypharmacy and frailty risk in Japanese community-dwelling older adults. METHODS:Participants included 299 non-frail older Japanese adults aged 65-81 years who particip...

journal_title：Geriatrics & gerontology international

authors： Yuki A,Otsuka R,Tange C,Nishita Y,Tomida M,Ando F,Shimokata H

更新日期：2018-10-01 00:00:00

abstract：AIM:The present study examined the association between vision, fear of falling and fear-related activity restriction, and assessed the effect of vision on the relationship between fear of falling and mobility, using data from a nationally representative sample of community-dwelling adults aged ≥ 50 years. METHODS:Part...

journal_title：Geriatrics & gerontology international

authors： Donoghue OA,Ryan H,Duggan E,Finucane C,Savva GM,Cronin H,Loughman J,Kenny RA

更新日期：2014-10-01 00:00:00

abstract：AIM:Increases in oxidative stress and advanced glycation end-products (AGE) formation play an important role in the pathogenesis of aging. Carnosine (CAR; β-alanyl-L-histidine) has anti-oxidant and antiglycating properties. We investigated the effect of CAR supplementation on AGE levels, and protein and lipid oxidation...

journal_title：Geriatrics & gerontology international

authors： Bingül İ,Yılmaz Z,Aydın AF,Çoban J,Doğru-Abbasoğlu S,Uysal M

更新日期：2017-12-01 00:00:00

abstract：AIM:Our aim was to study the outcome and the predictors of in-hospital cardiopulmonary resuscitation (CPR) among elderly patients admitted to Ain Shams University Hospitals, Egypt. METHODS:We carried out a cross-sectional study for all elderly patients (age ≥60 years) who underwent CPR after cardiac arrest at Ain Sham...

journal_title：Geriatrics & gerontology international

authors： Amer MS,Abdel Rahman TT,Aly WW,Ahmad NG

更新日期：2014-04-01 00:00:00

abstract：AIM:The purpose of this study was to determine the reference value for the Timed Up and Go test (TUG) in healthy Japanese elderly people using the methodology of meta-analysis, and to determine the value for different measurement protocols. METHODS:Relevant research articles were identified from electronic databases: ...

journal_title：Geriatrics & gerontology international

authors： Kamide N,Takahashi K,Shiba Y

更新日期：2011-10-01 00:00:00

abstract：AIM:Advanced glycation end-products are important factors in muscle function and physical performance among older adults. However, the association between sarcopenia and urinary carboxymethyl-lysine (uCML) levels remains unclear. The present study aimed to investigate the relationship among uCML levels, skeletal muscle...

journal_title：Geriatrics & gerontology international

authors： Yang CW,Li CI,Liu CS,Lin CH,Lin WY,Li TC,Lin CC

更新日期：2019-10-01 00:00:00

abstract：AIM:The aim of this study was to investigate the prevalence of self-reported oral complaints in older hospitalized mentally ill patients and relate them to the primary psychiatric diagnosis. METHODS:A total of 89 older hospitalized psychiatric patients consented to participate in the study, and were interviewed and cl...

journal_title：Geriatrics & gerontology international

authors： Kossioni AE,Kossionis GE,Polychronopoulou A

更新日期：2013-04-01 00:00:00

abstract：AIM:To determine if hospital treatment in residential care facilities, led by a geriatric team, might be a viable alternative to inpatient admission for selected patients. METHODS:Case series with a new intervention were compared with historical controls receiving the conventional treatment. Treatment in residential c...

journal_title：Geriatrics & gerontology international

authors： Lau L,Chong CP,Lim WK

更新日期：2013-04-01 00:00:00

abstract：AIM:The purposes of the present study were to investigate risk factors for incident disability in activities of daily living (ADL) among middle-aged and older women, and to determine whether there are differences in risk factors according to age groups. METHODS:The participants were 264 Japanese women aged 40 years an...

journal_title：Geriatrics & gerontology international

authors： Okabe T,Abe Y,Tomita Y,Mizukami S,Kanagae M,Arima K,Nishimura T,Tsujimoto R,Tanaka N,Goto H,Horiguchi I,Aoyagi K

更新日期：2017-07-01 00:00:00

abstract：AIM:Family function is an essential factor affecting older adults' health. However, there has been no appropriate method to assess the family function of most older adults with fragility or poor health status. The present study aimed to explore the differences and relevance of family function estimated by home care nur...

journal_title：Geriatrics & gerontology international

authors： Wang MW,Huang YY

更新日期：2016-06-01 00:00:00

abstract：AIM:The aims of the current study were to evaluate geriatric depression and its risk factors in advanced cancer patients. METHODS:A cross-sectional study was carried out in a palliative care unit in Greece. Patients completed the Geriatric Depression Scale, the M. D. Anderson Symptoms Instrument (MDASI), the Activitie...

journal_title：Geriatrics & gerontology international

authors： Mystakidou K,Parpa E,Tsilika E,Panagiotou I,Zygogianni A,Giannikaki E,Gouliamos A

更新日期：2013-04-01 00:00:00

abstract：AIM:To investigate whether positive affect independently predicts a lower risk of functional decline among community-dwelling older Japanese. METHODS:A 2-year prospective study was carried out among 505 residents of Tosa Town aged 65 years and older without disability in carrying out basic activities of daily living (...

journal_title：Geriatrics & gerontology international

authors： Hirosaki M,Ishimoto Y,Kasahara Y,Konno A,Kimura Y,Fukutomi E,Chen W,Nakatsuka M,Fujisawa M,Sakamoto R,Ishine M,Okumiya K,Otsuka K,Wada T,Matsubayashi K

更新日期：2013-10-01 00:00:00

abstract：AIM:The aim of the present study was to assess the relationship between neighborhood perception and poor self-rated health among older Mexican Americans, adjusting for important background characteristics, such as neighborhood ethnic composition and other health conditions. METHODS:Drawing on the 2004-2005 Hispanic Es...

journal_title：Geriatrics & gerontology international

authors： Stroope S,Cohen IFA,Tom JC,Franzen AB,Valasik MA,Markides KS

更新日期：2017-12-01 00:00:00

abstract：AIM:The aim of the present study was to examine whether behavioral and psychological symptoms of dementia at the time of admission could be a predictor of falls in older people with dementia residing in geriatric health service facilities. METHODS:Three geriatric health services facilities located in Fukushima Prefect...

journal_title：Geriatrics & gerontology international

authors： Sato S,Kakamu T,Hayakawa T,Kumagai T,Hidaka T,Masuishi Y,Endo S,Fukushima T

更新日期：2018-11-01 00:00:00

abstract：AIM:Low alanine aminotransferase (ALT) level is associated with frailty in the older adult population. We investigated the usefulness of ALT in predicting low muscle strength among older patients with diabetes. METHODS:We included 550 men aged ≥50 years and 525 postmenopausal women. All participants had diabetes, and ...

journal_title：Geriatrics & gerontology international

authors： Chung SM,Moon JS,Yoon JS,Won KC,Lee HW

更新日期：2020-04-01 00:00:00

abstract：AIM:The present study aimed to evaluate the relationship between the change of carotid intima-media thickness (CIMT) and clinical characteristics in Japanese patients without a history of cardiovascular disease. METHODS:The study participants were 149 Japanese patients without a history of cardiovascular disease treat...

journal_title：Geriatrics & gerontology international

authors： Watanabe K,Ouchi M,Ohara M,Kameda W,Susa S,Oizumi T,Wada M,Suzuki T,Kawanami T,Oba K,Kato T

更新日期：2015-08-01 00:00:00

abstract：AIM:The present study aimed to examine the associations among behavioral and psychological symptoms of dementia (BPSD) of persons with dementia (PWD), care burden and family-to-work conflict (FWC) of employed family caregivers. METHOD:A cross-sectional study was carried out with employed adult daughter or son (or in-l...

journal_title：Geriatrics & gerontology international

authors： Sakka M,Goto J,Kita S,Sato I,Soejima T,Kamibeppu K

更新日期：2019-01-01 00:00:00

abstract：AIM:Previous studies on health transition have focused on single-dimension outcomes and minimally evaluated heterogeneity. This study aimed to explore heterogeneous and multidimensional health-transition patterns on comorbidity, frailty and disability while examining the factors predicting different patterns of health ...

journal_title：Geriatrics & gerontology international

authors： Chang WC,Lu FP,Lan TY,Wu SC

更新日期：2013-07-01 00:00:00

abstract：AIMS:The purpose of this study was to determine the factors that adversely affect the weaning of elderly patients with community-acquired pneumonia from mechanical ventilation. METHODS:This study retrospectively investigated the medical records of 71 elderly patients (65 years or older) who were admitted to the hospit...

journal_title：Geriatrics & gerontology international

authors： Fujii M,Iwakami S,Takagi H,Itoigawa Y,Ichikawa M,Iwakami N,Ishiwata T,Seyama K,Takahashi K

更新日期：2012-04-01 00:00:00

abstract：AIM:To identify the association between different living arrangements of intergenerational household composition and depression in older adults. METHODS:Data from the Korea Longitudinal Study of Aging, the first to fourth waves, were used. Using the first wave as baseline, our analysis included 5046 participants aged ...

journal_title：Geriatrics & gerontology international

authors： Kim J,Choi Y,Choi JW,Nam JY,Park EC

更新日期：2017-12-01 00:00:00

abstract：AIM:Werner syndrome (WS) is an autosomal recessive disorder of progeroid symptoms and signs. It is caused by mutations in the WRN gene, which encodes a RecQ DNA helicase. The aim of this study was to revise the diagnostic criteria for Japanese Werner syndrome. METHODS:A nationwide epidemiological study was carried out...

journal_title：Geriatrics & gerontology international

authors： Takemoto M,Mori S,Kuzuya M,Yoshimoto S,Shimamoto A,Igarashi M,Tanaka Y,Miki T,Yokote K

更新日期：2013-04-01 00:00:00

abstract：AIM:To examine the efficacy of rehabilitation for elderly individuals with dementia at intermediate facilities between hospitals and home, based on the policies for elderly individuals to promote community-based care at home and dehospitalization. METHODS:Participants were older adults with dementia newly admitted to ...

journal_title：Geriatrics & gerontology international

authors： Toba K,Nakamura Y,Endo H,Okochi J,Tanaka Y,Inaniwa C,Takahashi A,Tsunoda N,Higashi K,Hirai M,Hirakawa H,Yamada S,Maki Y,Yamaguchi T,Yamaguchi H

更新日期：2014-01-01 00:00:00

abstract：AIMS:Existing analysis methods about the relationships between the long-term care (LTC) risks and determinants of the elderly often experience issues of independence, linearity and homogeneity. Such methodological issues are particularly problematic when the relationships are complicated, making the prioritization of L...

journal_title：Geriatrics & gerontology international

authors： Sato Osaki K,Zhang J,Kazawa K,Moriyama M

更新日期：2020-07-01 00:00:00

abstract：:We and other have recently shown that growth differentiation factor 15 (GDF15) is a useful diagnostic marker for mitochondrial diseases, which are inherited disorders caused by mitochondrial or nuclear genomic mutations that lead to impaired energy production. As the primary cause of mitochondrial diseases is mitochon...

journal_title：Geriatrics & gerontology international

authors： Fujita Y,Taniguchi Y,Shinkai S,Tanaka M,Ito M

更新日期：2016-03-01 00:00:00

abstract：AIM:To examine the association between depressive symptoms and all-cause mortality in a population-based prospective study. METHODS:Data from the 2008 baseline and 2011 follow-up assessments of the Living Profiles of Older People Survey involving 14 976 Korean adults aged ≥60 years (59% women) were used. Depressive sy...

journal_title：Geriatrics & gerontology international

authors： Park SH,Kim D,Cho J,Jin Y,Lee I,Lee K,Kang H

更新日期：2018-06-01 00:00:00

abstract：:More than 50 years ago, Hayflick et al. found that no long-lived, proliferative cells remained in long-term cell culture experiments; this phenomenon is called "cellular senescence." This finding has allowed us to understand basic individual tissue aging and cancer inhibition from the view of cellular aging. Senescent...

journal_title：Geriatrics & gerontology international

authors： Nakagami H

更新日期：2020-02-01 00:00:00

abstract：AIM:Sarcopenia causes a decline in physical performance and decreased quality of life. However, there is little evidence for effective treatments. Because of the similarities between osteoporosis and sarcopenia, alfacalcidol used for osteoporosis might be beneficial for low muscle mass. Therefore, we investigated the e...

journal_title：Geriatrics & gerontology international

authors： Ito S,Harada A,Kasai T,Sakai Y,Takemura M,Matsui Y,Hida T,Ishiguro N

更新日期：2014-02-01 00:00:00

abstract：AIMS:To determine the independent and combined associations of leisure-time physical activity (LTPA) and fruit and vegetable consumption with subsequent new depressive symptoms in Taiwanese aged ≥53 years. METHODS:We analyzed the 1999 and 2003 datasets of the Taiwan Longitudinal Survey on Aging and used the Center for...

journal_title：Geriatrics & gerontology international

authors： Chi SH,Wang JY,Tsai AC

更新日期：2016-02-01 00:00:00

abstract：AIM:Hemoglobin is reported to be positively associated with hypertension. However, the underlying mechanism of this association is unknown. Recently, bone marrow-derived CD34-positive cells have been reported to play an important role in endothelial repair in conjunction with platelets. As the association between hyper...

journal_title：Geriatrics & gerontology international

authors： Shimizu Y,Sato S,Koyamatsu J,Yamanashi H,Nagayoshi M,Kadota K,Kawashiri SY,Maeda T

更新日期：2017-12-01 00:00:00

abstract：AIMS:The aim of the present study was to evaluate whether there was an inflammation-mediated link between Alzheimer's disease (AD) and type 2 diabetes mellitus (DM) status. METHODS:An age-matched control group and patient groups designated as AD without treatment (AD); AD under cholinesterase inhibitors (AD-CEI); DM w...

journal_title：Geriatrics & gerontology international

authors： Bozluolcay M,Andican G,Fırtına S,Erkol G,Konukoglu D

更新日期：2016-10-01 00:00:00