Molecular properties of the fungal plasma-membrane [H+]-ATPase.

abstract：:Thirteen different polypeptide subunits, each in one copy, five phosphatidyl ethanolamines and three phosphatidyl glycerols, two hemes A, three Cu ions, one Mg ion, and one Zn ion are detectable in the crystal structure of bovine heart cytochrome c oxidase in the fully oxidized form at 2.8 A resolution. A propionate o...

journal_title：Journal of bioenergetics and biomembranes

authors： Yoshikawa S,Shinzawa-Itoh K,Tsukihara T

更新日期：1998-02-01 00:00:00

abstract：:The induction of millisecond delayed fluorescence mediated by PS I-dependent proton pumping has been used as an indicator of the time course with which those protons equilibrate with sites on the oxygen-evolving enzyme complex (Bowes, J. M., and Crofts, A. R. (1978). Z. Naturforsch. 33C, 271-275). We found that the in...

journal_title：Journal of bioenergetics and biomembranes

authors： Theg SM,Belanger KM,Dilley RA

更新日期：1987-02-01 00:00:00

abstract：:Extremely alkalophilic bacteria that grow optimally at pH 10.5 and above are generally aerobic bacilli that grow at mesophilic temperatures and moderate salt levels. The adaptations to alkalophily in these organisms may be distinguished from responses to combined challenges of high pH together with other stresses such...

journal_title：Journal of bioenergetics and biomembranes

authors： Krulwich TA,Guffanti AA

更新日期：1989-12-01 00:00:00

abstract：:Forkhead box protein O6 (FOXO6) has been recently identified as a novel regulator of oxidative stress in multiple pathological processes. However, whether FOXO6 participates in the regulation of oxidative stress of myocardial infarction is unclear. The present study was performed to evaluate the potential role of FOXO...

journal_title：Journal of bioenergetics and biomembranes

authors： Jin A,Zhang Q,Li S,Li B

更新日期：2020-12-01 00:00:00

abstract：:The chronology of the major discoveries important in elucidating certain aspects of the molecular basis of transmembrane signaling is briefly reviewed. Recent developments linking cell stimulation and transformation are intimated. ...

journal_title：Journal of bioenergetics and biomembranes

authors： Badwey JA

更新日期：1991-02-01 00:00:00

abstract：:Copper transporting P-type ATPases, designated ATP7A and ATP7B, play an essential role in mammalian copper balance. Impaired intestinal transport of copper, resulting from mutations in the ATP7A gene, lead to Menkes disease in humans. Defects in a similar gene, the copper transporting ATPase ATP7B, result in Wilson di...

journal_title：Journal of bioenergetics and biomembranes

authors： Cox DW,Moore SD

更新日期：2002-10-01 00:00:00

abstract：:Beef heart cytochrome c oxidase was reconstituted in asolectin liposomes containing the pH indicator fluorescein-phosphatidylethanolamine (FPE) by the cholate-dialysis procedure. The influence of FPE on the asolectin liposome size and of the removal of subunit III from the complex on its incorporation into liposomes w...

journal_title：Journal of bioenergetics and biomembranes

authors： Müller M,Azzi A

更新日期：1985-12-01 00:00:00

abstract：:Affinity labeling and genetic studies on the glycine-rich sequence of the beta subunit of E. coli F-type ATPase are discussed. A model of the structure of the enzyme near the gamma phosphate moiety is proposed. ...

journal_title：Journal of bioenergetics and biomembranes

authors： Futai M,Iwamoto A,Omote H,Maeda M

更新日期：1992-10-01 00:00:00

abstract：:In this study we used tightly-coupled mitochondria from Yarrowia lipolytica and Dipodascus (Endomyces) magnusii yeasts. The two yeast strains are good alternatives to Saccharomyces cerevisiae, being aerobes containing well structured mitochondria (thus ensuring less structural limitation to observe their appreciable s...

journal_title：Journal of bioenergetics and biomembranes

authors： Trendeleva T,Sukhanova E,Ural'skaya L,Saris NE,Zvyagilskaya R

更新日期：2011-12-01 00:00:00

abstract：:The transport systems of animal and human tissues for vitamin C are reviewed with respect to their properties. It emerges that pure diffusion plays only a very minor role while a variety of more or less specific transporters is found on cellular membranes. Although most tissues prefer the reduced ascorbate over the ox...

journal_title：Journal of bioenergetics and biomembranes

authors： Goldenberg H,Schweinzer E

更新日期：1994-08-01 00:00:00

abstract：:The serotonergic system plays a crucial role in the energy balance regulation. Energy balance is mediated by food intake and caloric expenditure. Thus, the present study investigated the mechanisms that might be associated with fluoxetine treatment-induced weight reduction. Wistar male rat pups received daily injectio...

journal_title：Journal of bioenergetics and biomembranes

authors： da Silva AI,Braz GR,Pedroza AA,Nascimento L,Freitas CM,Ferreira DJ,Manhães de Castro R,Lagranha CJ

更新日期：2015-08-01 00:00:00

abstract：:Reaction of a dog kidney (Na + K)-ATPase with pyridoxal phosphate, followed by borohydride reduction, reduced the catalytic activity when measured subsequently. The time course of inactivation did not follow a first-order process, and certain characteristics of the residual enzymatic activity were modified. Moreover, ...

journal_title：Journal of bioenergetics and biomembranes

authors： Robinson JD

更新日期：1984-06-01 00:00:00

abstract：:Escherichia coli has four [NiFe]-hydrogenases (Hyd); three of these, Hyd-1, Hyd-2 and Hyd-3 have been characterized well. In this study the requirement for the F(0)F(1)-ATP synthase for the activities of the hydrogen-oxidizing hydrogenases Hyd-1 and Hyd-2 was examined. During fermentative growth on glucose at pH 7.5 a...

journal_title：Journal of bioenergetics and biomembranes

authors： Trchounian K,Pinske C,Sawers RG,Trchounian A

更新日期：2011-12-01 00:00:00

abstract：:In this review, I focus on the bioenergetics of the methanogenic bacteria, with particular attention directed to the roles of transmembrane electrochemical gradients of sodium and proton. In addition, the mechanism of coupling ATP synthesis to methanogenic electron transfer is addressed. Evidence is reviewed which sug...

journal_title：Journal of bioenergetics and biomembranes

authors： Lancaster JR Jr

更新日期：1989-12-01 00:00:00

abstract：:Many oxidoreductases are constructed from (a) local sites of strongly coupled substrate-redox cofactor partners participating in exchange of electron pairs, (b) electron pair/single electron transducing redox centers, and (c) nonadiabatic, long-distance, single-electron tunneling between weakly coupled redox centers. ...

journal_title：Journal of bioenergetics and biomembranes

authors： Moser CC,Page CC,Farid R,Dutton PL

更新日期：1995-06-01 00:00:00

abstract：:The small alkylating molecule, 3-bromopyruvate (3BP), is a potent and specific anticancer agent. 3BP is different in its action from most currently available chemo-drugs. Thus, 3BP targets cancer cells' energy metabolism, both its high glycolysis ("Warburg Effect") and mitochondrial oxidative phosphorylation. This inh...

journal_title：Journal of bioenergetics and biomembranes

authors： Ko YH,Verhoeven HA,Lee MJ,Corbin DJ,Vogl TJ,Pedersen PL

更新日期：2012-02-01 00:00:00

abstract：:The mitochondrial ATP synthase is a membrane protein complex which couples the proton gradient across the mitochondrial inner membrane to the synthesis of ATP from ADP+Pi. The complex is composed of essential subunits for its motor functions and supernumerary subunits, the roles of which remain to be elucidated. Subun...

journal_title：Journal of bioenergetics and biomembranes

authors： Hong S,Pedersen PL

更新日期：2004-12-01 00:00:00

abstract：:Mitochondrial impairment has been collecting more and more attention as a contributing factor to the etiology of Parkinson's disease. Above all, the NADH-quinone oxidoreductase, complex I, of the respiratory chain seems to be most culpable. Complex I dysfunction is translated to an increased production of reactive oxy...

journal_title：Journal of bioenergetics and biomembranes

authors： Marella M,Seo BB,Yagi T,Matsuno-Yagi A

更新日期：2009-12-01 00:00:00

abstract：:The unique bifurcated oxidation of ubiquinol at center P (Qo) of the cytochrome bc1 complex is the reaction within the Q-cycle reaction scheme that is most critical for the link between electron transfer and vectorial proton translocation. While there is a general consensus about the overall reaction at center P, the ...

journal_title：Journal of bioenergetics and biomembranes

authors： Brandt U

更新日期：1999-06-01 00:00:00

abstract：:The purification of the channel-forming component of the mitochondrial calcium uniporter and its channel properties are described. After ethanol and 50% ethanol-water extraction of mitochondria from beef heart or perfused rat liver, the extract was passed through thiopropyl-Sepharose 6B column, and absorbed components...

journal_title：Journal of bioenergetics and biomembranes

authors： Mironova GD,Baumann M,Kolomytkin O,Krasichkova Z,Berdimuratov A,Sirota T,Virtanen I,Saris NE

更新日期：1994-04-01 00:00:00

abstract：:Liver mitochondria isolated from rats 24 h after a single subcutaneous injection of 8 mg thyroxine per kilogram body weight were compared with those isolated from control rats that received injections of isotonic saline at the same time. The mitochondria isolated from the thyroxine-treated rats show higher rates of en...

journal_title：Journal of bioenergetics and biomembranes

authors： Shears SB,Bronk JR

更新日期：1980-12-01 00:00:00

abstract：:Defects in Complex I of the mitochondrial respiratory chain have been identified in 38 patients. The clinical and laboratory features are reviewed and the results of recently devised strategies aimed at characterizing the primary molecular and genetic abnormalities are presented. Although not exhaustive, these studies...

journal_title：Journal of bioenergetics and biomembranes

authors： Morgan-Hughes JA,Schapira AH,Cooper JM,Clark JB

更新日期：1988-06-01 00:00:00

abstract：:At present there is a poor understanding of the events that lead up to neuronal apoptosis that occurs in neurodegenerative diseases and following acute ischemic episodes. Apoptosis is critical for the elimination of unwanted neurons within the developing nervous system. The Bcl-2 family of proteins contains pro- and a...

journal_title：Journal of bioenergetics and biomembranes

authors： Ward MW,Kögel D,Prehn JH

更新日期：2004-08-01 00:00:00

abstract：:Idebenone (IDE), a synthetic analog of coenzyme Q, strongly activates glycerol phosphate (GP) oxidation in brown adipose tissue mitochondria. GP oxidase, GP cytochrome c oxidoreductase and GP dehydrogenase activities were all significantly stimulated by 13 muM IDE. Substituted derivatives of IDE acetyl- and methoxyide...

journal_title：Journal of bioenergetics and biomembranes

authors： Rauchová H,Drahota Z,Bergamini C,Fato R,Lenaz G

更新日期：2008-04-01 00:00:00

abstract：:Vacuolar H+ ATPases participate in renal hydrogen ion secretion in both the proximal and distal nephron. These plasma membrane forms of the vacuolar H+ ATPase are regulated physiologically to maintain the acid-base balance of the organism. Proton transporting renal cells have requirements for constitutive acidificatio...

journal_title：Journal of bioenergetics and biomembranes

authors： Gluck SL

更新日期：1992-08-01 00:00:00

abstract：:Increased membrane unsaturation has been associated with shorter longevity due to higher sensitivity to lipid peroxidation (LP) leading to enhanced mitochondrial dysfunction and ROS overproduction. However, the role of LP during aging has been put in doubt along with the participation of electron leak at the electron ...

journal_title：Journal of bioenergetics and biomembranes

authors： Aguilar-Toral R,Fernández-Quintero M,Ortiz-Avila O,de la Paz LH,Calderón-Cortés E,Rodríguez-Orozco AR,Saavedra-Molina A,Calderón-Torres M,Cortés-Rojo C

更新日期：2014-06-01 00:00:00

abstract：:Results are presented which, taken with evidence developed by others, suggest a general mechanism for the entry and binding of exogenous ligands (including O2) at the "binuclear site" (CuBFea3) of the heme-copper oxidases. The mechanism includes a "ligand shuttle" wherein the obligatory way station for incoming ligand...

journal_title：Journal of bioenergetics and biomembranes

authors： Woodruff WH

更新日期：1993-04-01 00:00:00

abstract：:The protons excreted by plant cells may arise by two different mechanisms: (1) by the action of the plasma membrane H(+)-ATPase and (2) by plasma membrane redox reactions. The exact proportion from each source is not known, but the plasma membrane H(+)-ATPase is, by far, the major contributor to proton efflux. There i...

journal_title：Journal of bioenergetics and biomembranes

authors： Barr R

更新日期：1991-06-01 00:00:00

abstract：:The multidrug resistance (MDR) phenotype, frequently observed during cancer treatment, is often associated with drug efflux pump activity. However, many other factors are also known to be involved. Cancer cells often rely on aerobic glycolysis for energy production; this is known as the "Warburg effect" and is used as...

journal_title：Journal of bioenergetics and biomembranes

authors： Tavares-Valente D,Baltazar F,Moreira R,Queirós O

更新日期：2013-10-01 00:00:00

abstract：:We have previously shown that vacuolar H+-ATPase subcomplex V(o) from mung bean contains subunit d, however, its sequence and function were unknown. In the present study, we report the cloning and recombinant over expression of subunit d from mung bean in E. coli. To study the function of subunit d, two vacuolar H+-AT...

journal_title：Journal of bioenergetics and biomembranes

authors： Ouyang Z,Li Z,Zhang X

更新日期：2008-12-01 00:00:00