Abstract:
:With the introduction of topical corticosteroids, a milestone has been achieved in dermatologic therapy; owing to its potent anti-inflammatory and ant proliferative effects, it became possible to treat some hitherto resistant dermatoses. But this magic drug can cause enough mischief if used inappropriately. Children are more susceptible to the systemic adverse effects because of enhanced percutaneous absorption through their tender skin. So, systemic side effects should be kept in mind while prescribing this therapeutically valuable topical medicament.
journal_name
Indian J Dermatoljournal_title
Indian journal of dermatologyauthors
Dhar S,Seth J,Parikh Ddoi
10.4103/0019-5154.139874subject
Has Abstractpub_date
2014-09-01 00:00:00pages
460-4issue
5eissn
0019-5154issn
1998-3611pii
IJD-59-460journal_volume
59pub_type
杂志文章abstract::Keratoacanthoma (KA) is a rapidly evolving tumor, composed of keratinizing squamous cells originating in pilosebaceous follicles and resolving spontaneously if left untreated. It is relatively uncommon in dark-skinned and occurs in middle aged individuals. Males are three times more affected than females. It presents ...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.105316
更新日期:2013-01-01 00:00:00
abstract::A 42-year-old male developed hemorrhagic bullae and erosions while in alcohol induced coma. The lesions were limited to areas of the body in prolonged contact with the ground in the comatose state. He developed rhabdomyolysis, progressing to acute renal failure (ARF). Histopathological examination of the skin showed s...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.143576
更新日期:2014-11-01 00:00:00
abstract:Background:Sun exposure causes extensive intrinsic as well as extrinsic changes in the skin. Pathogenic effects of sun exposure such as tanning, melasma, skin cancer, and aggravation of various photodermatoses such as systemic lupus erythematosus (SLE) may be prevented by the use of sunscreens. We conducted the present...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/ijd.IJD_609_17
更新日期:2018-07-01 00:00:00
abstract::Use of immunohistochemical technique is increasing in diagnosing various diseases. In many situations it may not be possible to differentiate entities with overlapping clinical and histopathological features. Immunostaining of cellular antigens is immensely helpful in such cases. Immunohistochemistry (IHC) has also be...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.91818
更新日期:2011-11-01 00:00:00
abstract:BACKGROUND:It has been proposed that hepatitis C virus (HCV) antigens are involved in the pathogenesis of psoriasis and may contribute to severity of the disease. Increased expression of the apoptosis-regulating proteins p53 and tTG and decreased levels of bcl-2 in the keratinocytes of the skin of psoriatic patients ha...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.131377
更新日期:2014-05-01 00:00:00
abstract::Two adult patients from a village of district Bhilwara, Rajasthan, consulted Skin Department of R. N. T. Medical College and Hospital, Udaipur, with complaints of thickening of the palms and soles and pigmentation of skin with a nonhealing ulcer on the palm. They also had complaints of loss of appetite, abdominal pain...
journal_title:Indian journal of dermatology
pub_type:
doi:10.4103/ijd.IJD_704_16
更新日期:2019-03-01 00:00:00
abstract:Background:Leprosy is a chronic granulomatous infection primarily affecting the peripheral nervous system, skin and reticuloendothelial system. Cutaneous nerves are severely affected in lepra reaction and this leads to morbidity. Objective:To study electrophysiological pattern of different nerves involved in Type-II r...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/ijd.IJD_38_17
更新日期:2017-11-01 00:00:00
abstract::Cysticercosis is caused by cysticercus cellulose, which is the larva of Taenia solium, the pork tapeworm. The larvae are carried in the blood stream after penetrating the walls of the alimentary tract and they lodge in different tissues like the skin, skeletal muscles, brain, fundus and heart, to cause disseminated cy...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.48987
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Seborrheic keratosis (SK) is a benign epidermal tumor of unknown etiology. Because of its wart-like morphology, Human papillomaviruses (HPVs) have been suggested as a possible causative agent. Viral involvement, however, has not been confirmed yet despite research and the association between HPVs and seborrh...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.113949
更新日期:2013-07-01 00:00:00
abstract:Introduction:Mycobacterium leprae has a small genome and a tendency of persisting as a very low-grade infection. The authors have shown earlier, that the changes in TTC repeats, in M. leprae genome may contribute to the restriction of the pathogenicity of the bacterium and its survival strategy in case of pure neural H...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/ijd.IJD_90_18
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND:Alopecia areata (AA) is a common, chronic inflammatory disease characterized by nonscarring hair loss on the scalp or any hair-bearing area of the body. Recently, dermoscopy, a noninvasive diagnostic procedure, has been employed for the diagnosis of AA. AIM:To evaluate various dermoscopic patterns in AA and...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.193668
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Parthenium dermatitis is the most common type of airborne contact dermatitis in India. It is a chronic disease of a remitting and relapsing course with significant morbidity and distress, but there is no scoring system to assess its severity. AIM:To design a scoring system for the assessment of clinical sev...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.198037
更新日期:2017-01-01 00:00:00
abstract:INTRODUCTION:Neurogenic components, as neurotrophic factors and neuropeptides, are probably involved in the pathogenesis of atopic dermatitis (AD) with the neuroimmunocutaneous system as they modify the functions of immunoactive cells in the skin. Nerve growth factor (NGF) is the best-characterized member of the neurot...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.62735
更新日期:2010-04-01 00:00:00
abstract:BACKGROUND:Chronic urticaria (CU) is defined as urticaria persisting daily as or almost daily for more than 6 weeks and affecting 0.1% of the population. Mast cell degranulation and histamine release is of central importance in the pathogenesis of CU. About 40-50% of the patients with chronic idiopathic urticaria demon...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.103061
更新日期:2012-11-01 00:00:00
abstract::Behçet's disease (BD), first described by Hulusi Behcet, is a multisystemic disease characterized by recurrent oral and genital ulcerations, ocular and cutaneous lesions, arthritis and vascular disease. Pyoderma gangrenosum (PG) is a rare, chronic, sterile pustular and progressive ulcerative process of unknown cause; ...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.147866
更新日期:2015-01-01 00:00:00
abstract::We wish to report two cases of rickets due to vitamin D deficiency secondary to underlying ichthyotic skin disorder. The first case is of an 8-year-old male with history of multiple fluid-filled lesions over the body that would rupture to heal with thickening and scaling of skin, suggestive of epidermolytic hyperkerat...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.110877
更新日期:2013-05-01 00:00:00
abstract::Porokeratoma (acanthoma with features of porokeratosis) is a recently described entity with a distinct pattern of cornoid lamellation and clinically different from typical porokeratosis. We present a case of multiple porokeratomas on the buttock of a 78-year-old man with paraplegia secondary to poliomyelitis and ankyl...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.108073
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:Palmoplantar lesions in lichen planus (LP) are uncommon. In such cases, diagnosis is usually missed. This study was conducted to document various clinical and histopathological features of palmoplantar LP. MATERIALS AND METHODS:A total of 18 patients from our outpatient department with lesions of LP, either...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.135477
更新日期:2014-07-01 00:00:00
abstract::Acne vulgaris is one of the most commonly seen conditions and the immunological link is a topic of active research. Recently, the Th17 pathway has been found to play a pivotal role in acne. The adaptive immune response toward Propionibacterium acnes leads to activation of Th17 axis. Consequently, the Th17 cytokines (I...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/ijd.IJD_483_16
更新日期:2017-07-01 00:00:00
abstract::In genetically and phenotypically heterogeneous conditions like ichthyosis, it is clinically not possible to predict mutation in a specific gene. Sequential testing of all the causative genes is time consuming and expensive. In consanguineous families with autosomal recessive genetically heterogeneous disorders, it is...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.174134
更新日期:2016-01-01 00:00:00
abstract::Cutaneous pseudolymphomas are benign lymphoproliferative processes mimicking lymphomas clinically and histologically. One of the precipitating factors for pseudolymphoma is drugs like anticonvulsants, antidepressants and angiotensin-converting enzyme inhibitors. According to existing literature phenytoin-induced cutan...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.164437
更新日期:2015-09-01 00:00:00
abstract::Kindler's syndrome is a very rare genodermatosis characterized by acral blistering starting in infancy, photosensitivity, progressive poikiloderma, cutaneous atrophy, and various forms of mucosal involvement. A large number of other cutaneous and extracutaneous features have also been described. We report here three c...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.74568
更新日期:2010-10-01 00:00:00
abstract:CONTEXT:Alopecia areata (AA) is a common form of localized, non-scarring hair loss. The etiopathogenesis of the disease is still unclear, but the role of autoimmunity is strongly suggested. AA is commonly associated with various autoimmune disorders; the most frequent among them is autoimmune thyroid disorders. AIM:To...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.123494
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Vitiligo is one of the disorder that has social impact. Both skin and mucous membrane show depigmentation in vitiligo. Depigmentation in oral cavity can be more easily observed and the patient can be given awareness regarding the condition if they are unaware of vitiligo elsewhere in their body and can be gu...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.147844
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Warts are sometimes resistant or they tend to recur after every possible destructive therapy. Immunotherapy with skin-test antigens has been used as a viable therapeutic option in such recalcitrant cases. AIM:The aim of the study was to evaluate the response of resistant or recurrent warts to intralesional ...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.117301
更新日期:2013-09-01 00:00:00
abstract::The incidence of nonmelanoma skin cancer (NMSC) continues to rise, partly because of aging, the frequency of early childhood sunburns, and sporadic extreme recreational sun exposure. A nonsurgical approach to selected cutaneous malignancy could possibly reduce the cost as well as morbidity of surgical treatment for NM...
journal_title:Indian journal of dermatology
pub_type: 杂志文章,评审
doi:10.4103/0019-5154.143503
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND:Few clinical studies are found in the literature about patients hospitalized with a diagnosis of cutaneous drug eruption. AIMS:To determine the clinical types of drug eruptions and their causative agents in a hospital-based population. MATERIALS AND METHODS:This retrospective study was performed in the Der...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.96191
更新日期:2012-05-01 00:00:00
abstract:AIM:To evaluate the efficacy and safety of fixed drug combination (FDC) halometasone 0.05% and fusidic acid 2% (group A) vs FDC betamethasone 0.12% and neomycin sulfate 0.5% cream (group B) in acute or chronic infected eczematous dermatosis, through a randomized open-label, comparative, multicentric study. MATERIALS A...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.108041
更新日期:2013-03-01 00:00:00
abstract::We report a case of a 50-year-old female who presented with multiple thick-walled vesicles involving the labia majora and minora which started developing at the age of 10 year. The vesicles extruded milky white fluid when punctured. Biochemical analysis of the fluid was consistent with chyle. Lymphoscintigraphy showed...
journal_title:Indian journal of dermatology
pub_type:
doi:10.4103/ijd.IJD_76_19
更新日期:2020-03-01 00:00:00
abstract::Basal cell carcinoma is the most common nonmelanoma skin cancer. Its occurrence in the perianal region is very rare. Awareness of its benign behavior in this region, in contrast to the earlier reports, is vital in its management. Local excision seems to provide adequate control. We are herewith reporting an extremely ...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.62758
更新日期:2010-04-01 00:00:00