Abstract:
BACKGROUND:Seborrheic keratosis (SK) is a benign epidermal tumor of unknown etiology. Because of its wart-like morphology, Human papillomaviruses (HPVs) have been suggested as a possible causative agent. Viral involvement, however, has not been confirmed yet despite research and the association between HPVs and seborrheic keratosis has not been studied among Iranian population by PCR. OBJECTIVES:The aim of this case-control study was to evaluate the presence of HPVs DNA in non-genital SK by PCR. MATERIALS AND METHODS:Fifty biopsy specimens obtained from patients with non-genital SK and 50 controls were analyzed using polymerase chain reaction (PCR). RESULTS:No HPVs DNA was detected by PCR within the tissue extracts from paraffin-embedded SK samples, while one of the controls was HPVs DNA positive. The age range of the patients was 20 to 82 yrs (mean = 52). Twenty-eight patients (56%) were males and 22 patients (44%) were females. The most common anatomic site was the face. Histopathologic changes due to viral infection such as koilocytosis (10%), dyskeratosis (66%), mitosis (28%), and parakeratosis (88%) were evident within the lesions. The most common histologic type was acanthotic type. CONCLUSION:Our results showed that there is no association between HPVs and seborrheic keratosis in investigated subjects.
journal_name
Indian J Dermatoljournal_title
Indian journal of dermatologyauthors
Meibodi NT,Nahidi Y,Meshkat Z,Esmaili H,Gharib M,Gholoobi Adoi
10.4103/0019-5154.113949subject
Has Abstractpub_date
2013-07-01 00:00:00pages
326issue
4eissn
0019-5154issn
1998-3611pii
IJD-58-326bjournal_volume
58pub_type
杂志文章abstract:BACKGROUND:Parthenium dermatitis is the most common type of airborne contact dermatitis in India. It is a chronic disease of a remitting and relapsing course with significant morbidity and distress, but there is no scoring system to assess its severity. AIM:To design a scoring system for the assessment of clinical sev...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
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更新日期:2017-01-01 00:00:00
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journal_title:Indian journal of dermatology
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pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章,收录出版
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更新日期:2009-07-01 00:00:00
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journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.182426
更新日期:2016-05-01 00:00:00
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pub_type: 杂志文章
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更新日期:2015-03-01 00:00:00
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更新日期:2016-01-01 00:00:00
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journal_title:Indian journal of dermatology
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pub_type: 杂志文章
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更新日期:2017-11-01 00:00:00
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journal_title:Indian journal of dermatology
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更新日期:2008-01-01 00:00:00
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更新日期:2019-03-01 00:00:00