Abstract:
BACKGROUND:The anxiety disorders are a prevalent mental health problem in older age with a considerable impact on quality of life. Until recently there have been few longitudinal studies on anxiety in this age group, consequently most of the evidence to date has been cross-sectional in nature. METHODS:We undertook a literature search of Medline, PsycINFO, the Cochrane trials database and the TRIP medical database to identify longitudinal studies which would help elucidate natural history and prognosis of anxiety disorders in the elderly. RESULTS:We identified 12 papers of 10 longitudinal studies in our Review. This represented 34,691 older age participants with 5,199 with anxiety disorders including anxious depression and 3,532 individuals with depression without anxiety. Relapse rates of anxiety disorders are high over 6 year follow-up with considerable migration to mixed anxiety-depression and pure depressive mood episodes. Mixed anxiety-depression appears to be a poorer prognostic state than pure anxiety or pure depression with higher relapse rates across studies. In community settings treatment rates are low with 7-44% of the anxious elderly treated on antidepressant medications. CONCLUSIONS:To our knowledge this is the first Systematic Review of longitudinal trials of anxiety disorders in older people. Major longitudinal studies of the anxious elderly are establishing the high risk of relapse and persistence alongside the progression to depression and anxiety depression states. There remains considerable under-treatment in community studies. Specialist assessment and treatment and major public health awareness of the challenges of anxiety disorders in the elderly are required.
journal_name
Int Psychogeriatrjournal_title
International psychogeriatricsauthors
Sami MB,Nilforooshan Rdoi
10.1017/S1041610214001847subject
Has Abstractpub_date
2015-07-01 00:00:00pages
1061-9issue
7eissn
1041-6102issn
1741-203Xpii
S1041610214001847journal_volume
27pub_type
杂志文章,评审abstract:OBJECTIVE:Cognitive impairment and negative signs are common in patients with schizophrenia. Up to 35% of elderly patients with schizophrenia fulfill the diagnostic criteria of dementia. Donepezil inhibits cholinesterase, thus enhancing cholinergic neurotransmission. We tested the efficacy of donepezil in elderly patie...
journal_title:International psychogeriatrics
pub_type: 杂志文章,随机对照试验
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更新日期:2006-09-01 00:00:00
abstract:BACKGROUND:Previous studies have thoroughly investigated the prevalence and risk factors for completed suicide. In marked contrast is the lack of a better understanding of attempted suicide in the elderly. The aim of this study was to estimate the prevalence of attempted suicide in the elderly and examine the associate...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610216002283
更新日期:2017-05-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
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更新日期:2020-03-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610203009293
更新日期:2003-01-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610212001743
更新日期:2013-02-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610214001859
更新日期:2014-12-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1992-07-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610297004213
更新日期:1997-03-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章,评审
doi:10.1017/S1041610214002877
更新日期:2015-08-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610213001142
更新日期:2013-11-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610212000051
更新日期:2012-07-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610210000050
更新日期:2010-08-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610210000669
更新日期:2010-08-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1017/S1041610203009190
更新日期:2003-01-01 00:00:00
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journal_title:International psychogeriatrics
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更新日期:2011-02-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
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更新日期:2013-09-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610219001789
更新日期:2019-12-23 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610219001431
更新日期:2020-03-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
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更新日期:2018-03-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
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更新日期:2011-06-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610201007438
更新日期:2001-03-01 00:00:00
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pub_type: 杂志文章
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更新日期:2019-04-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610209009454
更新日期:2009-08-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610213000446
更新日期:2013-07-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610213002081
更新日期:2014-03-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610210001109
更新日期:2011-04-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 历史文章,杂志文章,评审
doi:10.1017/S1041610211001864
更新日期:2012-02-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 社论
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更新日期:2018-07-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
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更新日期:2011-11-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610212000749
更新日期:2012-10-01 00:00:00