Abstract:
:Galgeun-tang (GT) prior to and following fermentation with Lactobacillus plantarum was analyzed to determine the total polyphenol and flavonoid contents and the antioxidant activity. GT, fermented GT (FGT) and their three solvent-partitioned fractions, which were prepared by successive partitioning with ethyl acetate (EtOAc), butanol (BuOH) and water, were evaluated for total polyphenol and flavonoid contents, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity and xanthine oxidase (XO) inhibitory activity. Following fermentation, the total polyphenol content only increased slightly; however, the flavonoid content increased by 24.3%. The radical scavenging activity increased from 22.4 to 27.5% and the XO inhibitory activity increased from 20.2 to 62.4% at 500 µg/ml. The EtOAc fraction among the solvent‑partitioned fractions demonstrated the highest total polyphenol and flavonoid contents, radical scavenging activities and XO inhibitory activity, and the quantity also markedly increased following fermentation.
journal_name
Mol Med Repjournal_title
Molecular medicine reportsauthors
Kim DS,Um YR,Ma JYdoi
10.3892/mmr.2014.2487subject
Has Abstractpub_date
2014-11-01 00:00:00pages
2689-93issue
5eissn
1791-2997issn
1791-3004journal_volume
10pub_type
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