Comparison of two 22 G aspiration needles for histologic sampling during endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA).

Abstract:

OBJECTIVE:Endobronchial ultrasound-guided transbronchial needle aspiration is widely used for mediastinal and hilar lesions. Histologic specimens from this procedure are important for specific diagnosis and targeted therapy. Studies on the traditional endobronchial ultrasound-guided transbronchial needle aspiration needles reported yields of only 50-60% for diagnostic histologic specimens. Recently, a new needle has become available in Europe, USA and Asia. The investigators aimed to evaluate the histologic specimen retrieval yields of the two needles. METHODS:Patients who underwent endobronchial ultrasound-guided transbronchial needle aspiration with the new 22 G needle (M group, n = 94) were compared with a historical control group who underwent endobronchial ultrasound-guided transbronchial needle aspiration with the traditional 22 G needle (O group, n = 82). The quality of needle aspirates from both groups was evaluated. RESULTS:There were no significant differences between the two groups in terms of demographics, lesion characteristics, primary disease and examiner experience. The M group had a significantly shorter procedure time than the O group (P = 0.049). Of the 214 punctures by the M group, 159 (74.3%) were diagnostic, 28 (13.1%) were non-diagnostic and 27 (12.6%) had no histologic specimen. The 235 punctures by the O group were diagnostic in 144 (61.3%), non-diagnostic in 60 (25.5%) and had no histologic specimen in 31 (13.2%). The yield for diagnostic histologic specimens of the M group was significantly higher than the O group (P = 0.0035). There were no major complications observed. CONCLUSIONS:The yield for diagnostic histologic specimens by the new 22 G endobronchial ultrasound-guided transbronchial needle aspiration needle was high. Further technical improvements of histologic sampling yields are very important when selecting targeted therapy.

journal_name

Jpn J Clin Oncol

authors

Izumo T,Sasada S,Watanabe J,Chavez C,Matsumoto Y,Tsuchida T

doi

10.1093/jjco/hyu095

subject

Has Abstract

pub_date

2014-09-01 00:00:00

pages

841-5

issue

9

eissn

0368-2811

issn

1465-3621

pii

hyu095

journal_volume

44

pub_type

杂志文章
  • Epidemiology, tumor characteristics and survival in patients with angiosarcoma in the United States: a population-based study of 4537 cases.

    abstract:OBJECTIVE:Limited by sample size, angiosarcoma was rarely studied. We aimed to investigate the characteristics and prognosis of angiosarcoma in the National Cancer Institute's Surveillance, Epidemiology and End Results database. METHODS:Patients who were diagnosed with primary angiosarcoma from 1973 to 2014 were extra...

    journal_title:Japanese journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1093/jjco/hyz113

    authors: Zhang C,Xu G,Liu Z,Xu Y,Lin F,Baklaushev VP,Chekhonin VP,Peltzer K,Mao M,Wang X,Wang G,Zhang C

    更新日期:2019-12-27 00:00:00

  • Immunomodulatory drugs in the treatment of multiple myeloma.

    abstract::The prognosis of multiple myeloma was quite poor in the last century, but it has significantly improved with the incorporation of novel agents, immunomodulatory drugs (IMiDs) and proteasome inhibitors. Thalidomide was first developed as a sedative in 1950s, but it was withdrawn from the market because of teratogenicit...

    journal_title:Japanese journal of clinical oncology

    pub_type: 杂志文章,评审

    doi:10.1093/jjco/hyz083

    authors: Abe Y,Ishida T

    更新日期:2019-08-01 00:00:00

  • Adenoid basal carcinoma of the uterine cervix: immunohistochemical study and literature review.

    abstract::Adenoid basal carcinoma of the uterine cervix is rare and its cell origin is still obscure. We report a case of adenoid basal carcinoma of the uterine cervix discovered incidentally in a 69-year-old woman who had been hysterectomized due to endometrial adenocarcinoma of the uterine corpus. Histologically, small round-...

    journal_title:Japanese journal of clinical oncology

    pub_type: 杂志文章,评审

    doi:10.1093/jjco/27.6.437

    authors: Senzaki H,Osaki T,Uemura Y,Kiyozuka Y,Ogura E,Okamura A,Tsubura A

    更新日期:1997-12-01 00:00:00

  • Multicenter feasibility study of combination therapy with fluorouracil, leucovorin and paclitaxel (FLTAX) for peritoneal disseminated gastric cancer with massive ascites or inadequate oral intake.

    abstract:OBJECTIVE:Oral fluoropyrimidine plus cisplatin is a standard treatment for advanced gastric cancer, but patients with severe peritoneal metastasis often cannot tolerate this regimen. The aim of this study was to assess the feasibility of fluorouracil, l-leucovorin and paclitaxel therapy in such patients. METHODS:In th...

    journal_title:Japanese journal of clinical oncology

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1093/jjco/hys111

    authors: Iwasa S,Goto M,Yasui H,Nishina T,Takahari D,Nakayama N,Taira K,Kusaba H,Fuse N,Hironaka S,Shimada Y,Nakajima TE

    更新日期:2012-09-01 00:00:00

  • MicroRNAs in Cancer: the 22nd Hiroshima Cancer Seminar/the 4th Japanese Association for RNA Interference Joint International Symposium, 30 August 2012, Grand Prince Hotel Hiroshima.

    abstract::The joint international symposium of the 22nd Hiroshima Cancer Seminar and the 4th Japanese Association for RNA Interference focused on a pivotal role of microRNAs in carcinogenesis, progression and therapy of human cancer. Mammalian immune regulator MCPIP1 (Zc3h12a) RNase acts as a novel suppressor of microRNA activi...

    journal_title:Japanese journal of clinical oncology

    pub_type:

    doi:10.1093/jjco/hyt037

    authors: Tahara H,Kay MA,Yasui W,Tahara E

    更新日期:2013-05-01 00:00:00

  • Surgical results of lung cancer with sarcoid reaction in regional lymph nodes.

    abstract:BACKGROUND:There have been few reports of sarcoid reaction in the regional lymph nodes associated with lung cancer. The purpose of this study was to analyze the surgical results of lung cancer with sarcoid reaction. METHODS:Of 1733 lung cancer patients undergoing surgical treatment in our institute from 1990 to 2004, ...

    journal_title:Japanese journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1093/jjco/hyl141

    authors: Tomimaru Y,Higashiyama M,Okami J,Oda K,Takami K,Kodama K,Tsukamoto Y

    更新日期:2007-02-01 00:00:00

  • Pure red cell aplasia associated with non-Hodgkin's lymphoma and hemolytic anemia.

    abstract::Pure red cell aplasia (PRCA) rarely occurs in non-thymic lymphoproliferative disorders. The present article describes a patient with non-Hodgkin's lymphoma (follicular, mixed type), who concurrently developed PRCA and warm type autoimmune hemolytic anemia during the clinical course. The PRCA and hemolytic anemia were ...

    journal_title:Japanese journal of clinical oncology

    pub_type: 杂志文章

    doi:

    authors: Suzuki A,Takahashi T,Taniguchi A,Kotake C,Seo T,Toda T,Kobayashi K,Tsukamoto N,Fukumoto M

    更新日期:1991-10-01 00:00:00

  • Cumulative incidence, risk factors and prognostic impact of venous thromboembolism in Japanese patients with advanced gastric cancer.

    abstract:Background:Advanced gastric cancer (AGC) and systemic chemotherapy are some of the risk factors for venous thromboembolism (VTE). However, the cumulative incidence, risk factors and prognostic impact of VTE have not been evaluated in Japanese patients with AGC. Methods:This retrospective study included patients who re...

    journal_title:Japanese journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1093/jjco/hyx107

    authors: Arai H,Hironaka S,Minashi K,Denda T,Shimokawa M,Yamaguchi T

    更新日期:2017-10-01 00:00:00

  • A phase II clinical study of mFOLFOX6 plus bevacizumab as first-line therapy for Japanese advanced/recurrent colorectal cancer patients.

    abstract:OBJECTIVE:In Japan, there had been no prospective clinical studies conducted in terms of modified FOLFOX6 + bevacizumab therapy. We performed a post-marketing Phase II multicenter clinical study to examine the efficacy and safety of this regimen as first-line therapy for Japanese patients with advanced/recurrent colore...

    journal_title:Japanese journal of clinical oncology

    pub_type: 杂志文章,多中心研究

    doi:10.1093/jjco/hyt127

    authors: Nishina T,Takano Y,Denda T,Yasui H,Takeda K,Ura T,Esaki T,Okuyama Y,Kondo K,Takahashi Y,Sugiyama Y,Muro K

    更新日期:2013-11-01 00:00:00

  • Feasibility study of the simultaneous integrated boost (SIB) method for malignant gliomas using intensity-modulated radiotherapy (IMRT).

    abstract:BACKGROUND:Intensity-modulated radiotherapy (IMRT) using the simultaneous integrated boost (SIB) method was designed for treating malignant gliomas. The purpose of this study was to investigate feasibility of this treatment. METHODS:Between December 2000 and November 2002, six patients with malignant gliomas were enro...

    journal_title:Japanese journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1093/jjco/hyg053

    authors: Suzuki M,Nakamatsu K,Kanamori S,Okumra M,Uchiyama T,Akai F,Nishimura Y

    更新日期:2003-06-01 00:00:00

  • Successful treatment of pulmonary artery sarcoma by a two-drug combination chemotherapy consisting of ifosfamide and epirubicin.

    abstract::We describe a case of 63-year-old woman with pulmonary artery sarcoma successfully treated with chemotherapy. She developed acute shortness of breath, and left chest and shoulder pain. Although a diagnosis of acute pulmonary embolism was made at a local hospital and she received anticoagulation and thrombolysis therap...

    journal_title:Japanese journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1093/jjco/hyi106

    authors: Uchida A,Tabata M,Kiura K,Tanimoto Y,Kanehiro A,Aoe M,Ohohara N,Ueoka H,Tanimoto M

    更新日期:2005-07-01 00:00:00

  • Clinical significance of bone marrow micrometastasis detected by nested rt-PCR for keratin-19 in breast cancer patients.

    abstract:PURPOSE:Breast cancers in the early phase frequently undergo distant metastasis and survival of patients is greatly dependent on distant metastasis. The occurrence of micrometastasis has been suggested to relate with prognostic features of breast cancer, such as lymph node metastasis and the presence of vascular invasi...

    journal_title:Japanese journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1093/jjco/hyg038

    authors: Jung YS,Lee KJ,Kim HJ,Yim HE,Park JS,Soh EY,Kim MW,Park HB

    更新日期:2003-04-01 00:00:00

  • Prognostic factors and therapeutic options of radiotherapy in pediatric brain stem gliomas.

    abstract:BACKGROUND:A retrospective analysis was made to clarify the relationship between prognosis, radiation dose and survival of brain stem gliomas. METHODS:From 1983 to 1995, 22 children with brain stem tumors were treated by radiotherapy in the Veterans General Hospital-Taipei. Twelve patients had pathology proof and the ...

    journal_title:Japanese journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1093/jjco/28.8.474

    authors: Liu YM,Shiau CY,Wong TT,Wang LW,Wu LJ,Chi KH,Chen KY,Yen SH

    更新日期:1998-08-01 00:00:00

  • Hyperfractionated radiation therapy for locoregionally advanced nasopharyngeal cancer.

    abstract:OBJECTIVE:The purpose of this study is to clarify the efficacy and toxicity of hyperfractionated radiation therapy (RT) for patients with nasopharyngeal cancer (NPC). METHODS:Twenty-two patients with NPC treated at our hospital between April 1994 and December 2002 were the subjects of this study. They received hyperfr...

    journal_title:Japanese journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1093/jjco/hyi041

    authors: Isobe K,Uno T,Kawakami H,Ueno N,Aruga T,Yasuda S,Hanazawa T,Okamoto Y,Ito H,Shigematsu N

    更新日期:2005-03-01 00:00:00

  • A newly introduced comprehensive consultation fee in the national health insurance system in Japan: a promotive effect of multidisciplinary medical care in the field of radiation oncology--results from a questionnaire survey.

    abstract:OBJECTIVE:The consultation fee for outpatient radiotherapy was newly introduced in the national health insurance system in Japan in April 2012. We conducted a survey on the use of this consultation fee and its effect on clinical practices. METHODS:The health insurance committee of the Japanese Society of Therapeutic R...

    journal_title:Japanese journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1093/jjco/hyt147

    authors: Igaki H,Onishi H,Nakagawa K,Dokiya T,Nemoto K,Shigematsu N,Nishimura Y,Hiraoka M,Japanese Society for Therapeutic Radiology and Oncology Health Insurance Committee.

    更新日期:2013-12-01 00:00:00

  • Distribution and clinical significance of circulating tumor cells in nasopharyngeal carcinoma.

    abstract:OBJECTIVE:Nasopharyngeal carcinoma is one of the leading malignancies with obscure etiology. Circulating tumor cells have been showed to intimately correlate with characteristics in different kinds of cancer. But links between circulating tumor cells and nasopharyngeal carcinoma were still lacking. Therefore, we explor...

    journal_title:Japanese journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1093/jjco/hyw046

    authors: Si Y,Lan G,Deng Z,Wang Y,Lu Y,Qin Y,Huang B,Yang Y,Weng J,Han X,Zhang B,Qin Y,Xiong W,Li B,Wu S

    更新日期:2016-07-01 00:00:00

  • Phyllodes tumor of the prostate: a case report.

    abstract::A case of prostatic phyllodes tumor which developed in a 78-yr-old man is reported. Histologically, the tumor comprised myxomatous and cellular portions with a proliferation of atypical stromal cells. Multinucleated giant cells were occasionally present, but mitoses were rare. Fibroblastic differentiation of the tumor...

    journal_title:Japanese journal of clinical oncology

    pub_type: 杂志文章,评审

    doi:

    authors: Ito H,Ito M,Mitsuhata N,Tahara E

    更新日期:1989-09-01 00:00:00

  • Statistical inference for estimating the incidence of cancer at the prefectural level in Japan.

    abstract::Information of prefectural cancer incidence in Japan is an important resource to plan an effective regional cancer control program. In order to obtain accurate prefectural cancer incidence, we have to adjust for both of completeness of regional cancer registries and regional dispersion, simultaneously, Then, we develo...

    journal_title:Japanese journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1093/jjco/hyz033

    authors: Tanabe R,Kamo KI,Fukui K,Imori S

    更新日期:2019-05-01 00:00:00

  • Repression of the expression of PPP3CC by ZEB1 confers activation of NF-κB and contributes to invasion and growth in glioma cells.

    abstract:Background:Gliomas are highly malignant brain tumors. Aberrant activation of NF-κB plays a crucial role in tumor progression. Method:ELISA assay was used to detect NF-κB activity in glimoas cells with different treatments. PPP3CC expression was evaluated by qRT-PCR and western blot assay. Kaplan-Meier analysis estimat...

    journal_title:Japanese journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1093/jjco/hyx182

    authors: Wang H,Zhao S,Chen B,Fu C,Dang Y,Fang P,Wang J,Wang N,Liu L

    更新日期:2018-02-01 00:00:00

  • Weekly hepatic arterial infusion of 5-fluorouracil and subsequent systemic chemotherapy for liver metastases from colorectal cancer.

    abstract:OBJECTIVE:To determine the antitumor activity and toxicity of weekly hepatic arterial infusion (HAI) of 5-fluorouracil (5-FU) for liver metastases from colorectal cancer. In addition, the present study also evaluated the efficacy of second-line chemotherapy after termination of HAI. METHODS:A retrospective study was d...

    journal_title:Japanese journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1093/jjco/hyg021

    authors: Hosokawa A,Yamada Y,Shimada Y,Muro K,Matsumura Y,Fujita S,Akasu T,Moriya Y,Shirao K

    更新日期:2003-03-01 00:00:00

  • Immunotherapy for squamous cell carcinoma of the head and neck.

    abstract::Squamous cell carcinoma of the head and neck is characterized by an immunosuppressive environment and evades immune responses through multiple resistance mechanisms. A breakthrough in cancer immunotherapy employing immune checkpoint inhibitors has evolved into a number of clinical trials with antibodies against progra...

    journal_title:Japanese journal of clinical oncology

    pub_type: 杂志文章,评审

    doi:10.1093/jjco/hyaa139

    authors: Yokota T,Homma A,Kiyota N,Tahara M,Hanai N,Asakage T,Matsuura K,Ogawa T,Saito Y,Sano D,Kodaira T,Motegi A,Yasuda K,Takahashi S,Tanaka K,Onoe T,Okano S,Imamura Y,Ariizumi Y,Hayashi R,Japan Clinical Oncology Group (

    更新日期:2020-09-28 00:00:00

  • Relationship between tumor-infiltrating T lymphocytes and clinical response after reduced-intensity allogeneic hematopoietic stem cell transplantation for advanced renal cell carcinoma: a single center prospective study.

    abstract:OBJECTIVE:Renal cell carcinoma (RCC) is refractory to conventional therapy, including chemotherapy and radiation. However, because RCC is sensitive to cytokine therapy, an immunotherapeutic approach such as hematopoietic stem cell transplantation (HSCT) might lead to a cure. We performed an institutional clinical study...

    journal_title:Japanese journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1093/jjco/hyp104

    authors: Ishiyama K,Takami A,Suzuki S,Konaka H,Namiki M,Ooi A,Nakao S

    更新日期:2009-12-01 00:00:00

  • Helpful parameter for malignant potential of gastrointestinal stromal tumors (GIST).

    abstract:BACKGROUND:Although a series of histopathological criteria have been suggested, the prediction of the malignant potential of gastrointestinal stromal tumors (GIST) is still difficult. The older literature called all gastrointestinal stromal tumors smooth muscle tumors or mixed GIST with true smooth muscle tumors. Repor...

    journal_title:Japanese journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1093/jjco/hyf074

    authors: Wang X,Mori I,Tang W,Utsunomiya H,Nakamura M,Nakamura Y,Zhou G,Kennichi K

    更新日期:2002-09-01 00:00:00

  • Concurrent chemoradiotherapy with protracted infusion of 5-FU and cisplatin for postoperative recurrent or residual esophageal cancer.

    abstract:BACKGROUND:We carried out the present study to investigate the feasibility and effectiveness of concurrent chemoradiotherapy (CT-RT) for postoperative recurrent esophageal cancer, which are, at present, unclear. METHODS:Between 1998 and 2002, 16 patients with postoperative loco-regional recurrence of esophageal cancer...

    journal_title:Japanese journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1093/jjco/hyg065

    authors: Nishimura Y,Koike R,Nakamatsu K,Kanamori S,Suzuki M,Shigeoka H,Shiozaki H

    更新日期:2003-07-01 00:00:00

  • Effectiveness of rapid titration with intravenous administration of oxycodone injection in advanced cancer patients with severe pain.

    abstract::Some cancer patients suddenly develop severe, excruciating pain that requires rapid management using opioid medication. This study aimed to evaluate the effectiveness of rapid titration using oxycodone injection. Study subjects were advanced cancer patients who experienced severe pain (numeric rating scale ≥7) and nee...

    journal_title:Japanese journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1093/jjco/hyz145

    authors: Nakajima N

    更新日期:2019-12-18 00:00:00

  • Identity of brain-associated small cell lung cancer antigen and the CD56 (NKH-1/Leu-19) leukocyte differentiation antigen and the neural cell adhesion molecule.

    abstract::Previous studies have demonstrated the monoclonal antibody, TFS-4, to recognize a cell surface antigen, 124,000 Daltons, of molecular weight expressed selectively on small cell lung cancer but not on non-small cell lung cancer, and to cross-react with the human brain, cardiac muscle and some smooth muscle cells. The c...

    journal_title:Japanese journal of clinical oncology

    pub_type: 杂志文章

    doi:

    authors: Umezawa Y,Kuge S,Kikyo N,Shirai T,Watanabe J,Fugisawa M,Okabe T

    更新日期:1991-08-01 00:00:00

  • A phase II study of high-dose epirubicin (EPI) plus cyclophosphamide (CPA) with G-CSF for breast cancer patients with visceral metastases or hormone-independent tumors: a trial of the Japan Clinical Oncology Group.

    abstract::To evaluate the efficacy and toxicity of high-dose epirubicin (EPI) plus cyclophosphamide (CPA) therapy, a phase II study of EPI, 130 mg/m2, plus CPA, 1000 mg/m2, with G-CSF every 3 weeks was carried out for 51 advanced or recurrent breast cancer patients by the Japan Clinical Oncology Group (JCOG). Fifty out of the 5...

    journal_title:Japanese journal of clinical oncology

    pub_type: 临床试验,杂志文章

    doi:10.1093/jjco/27.5.325

    authors: Takashima S,Saeki T,Adachi I,Watanabe T,Sasaki Y,Murai H,Tabei T,Ogita M,Sano M,Kanda K,Shimoyama M

    更新日期:1997-10-01 00:00:00

  • Cancer epidemiology and control in Taiwan: a brief review.

    abstract::Malignant neoplasm has become the leading cause of death in Taiwan since 1982. There has been a decreasing trend for cancers of the stomach and cervix uteri, while an increasing trend has been observed for cancers of the lung, liver, oral cavity, colon and rectum, breast and prostate. International comparison and migr...

    journal_title:Japanese journal of clinical oncology

    pub_type: 杂志文章,评审

    doi:10.1093/jjco/hye138

    authors: Chen CJ,You SL,Lin LH,Hsu WL,Yang YW

    更新日期:2002-03-01 00:00:00

  • Phase II trial of concurrent chemoradiotherapy with S-1 plus cisplatin in patients with unresectable locally advanced squamous cell carcinoma of the head and neck: Japan Clinical Oncology Group Study (JCOG0706).

    abstract::A Phase II study was started in Japan to evaluate the efficacy and safety of concurrent chemoradiotherapy with S-1 plus cisplatin in patients with unresectable locally advanced squamous cell carcinoma of the head and neck. This study began in July 2008, and a total of 45 patients will be accrued from 13 institutions w...

    journal_title:Japanese journal of clinical oncology

    pub_type: 杂志文章,多中心研究

    doi:10.1093/jjco/hyp040

    authors: Nakamura K,Tahara M,Kiyota N,Hayashi R,Akimoto T,Fukuda H,Fujii M,Boku N

    更新日期:2009-07-01 00:00:00

  • Treatment of hepatocellular carcinoma using arterial chemoembolization with degradable starch microspheres and continuous arterial infusion of 5-fluorouracil.

    abstract:OBJECTIVE:Transcatheter arterial embolization (TAE) with gelatin sponge particles and iodized oil often yields poor results when used to treat unresectable multifocal hepatocellular carcinoma (HCC). The present study retrospectively investigated the utility of a novel combination chemotherapy regimen for treating multi...

    journal_title:Japanese journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1093/jjco/hyn076

    authors: Ishida K,Hirooka M,Hiraoka A,Kumagi T,Uehara T,Hiasa Y,Horiike N,Onji M

    更新日期:2008-09-01 00:00:00