Serum procalcitonin levels in patients with ankylosing spondylitis.

Abstract:

AIM:Procalcitonin is a marker of bacterial and fungal infection and sepsis. The present study evaluated the relationship between serum procalcitonin levels and disease activity in patients with ankylosing spondylitis (AS). METHOD:A total of 61 patients who met the 1984 New York criteria for AS were studied. Twenty-four age- and sex-matched healthy volunteers were recruited to this study as a control group. Disease activity was assessed by the Bath AS Disease Activity Index (BASDAI). The functional status of patients was evaluated by the Bath AS Functional Index (BASFI). Spinal mobility was measured by the Bath AS Metrology Index (BASMI). Erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and serum procalcitonin levels were measured. RESULTS:Thirty patients were on anti-tumor necrosis factor-alpha treatment and 31 patients were on conventional treatment. Seventeen (28%) of the AS patients were active (BASDAI > 4) and 44 (72%) of the AS patients were in remission. The median ESR was 14 (34-6) mm/h and 4 (7-2) mm/h (P < 0.001) for the patient and control groups, respectively. The median CRP level was 0.91 (2.72-0.37) mg/dL and 0.15 (0.25-0.07) mg/dL in the patient and control groups, respectively (P < 0.001). Median BASDAI, BASFI and BASMI scores for all AS patients were 3.6 (5.25-2.29), 2.5 (4.22-0.91) and 3 (5-1), respectively. Serum procalcitonin levels were normal (< 0.05 ng/mL) for all patients and controls. CONCLUSION:Serum procalcitonin levels were not high in AS patients and controls, and the levels were independent of disease activity and medications. If bacterial or fungal infection is suspected in an AS patient, serum procalcitonin level may be useful for diagnosis.

journal_name

Int J Rheum Dis

authors

Ozmen M,Oktay E,Tarhan EF,Aslan O,Oflazoglu U,Koseoglu MH

doi

10.1111/1756-185X.12386

subject

Has Abstract

pub_date

2016-05-01 00:00:00

pages

500-5

issue

5

eissn

1756-1841

issn

1756-185X

journal_volume

19

pub_type

杂志文章
  • Autoantibody profile in children with Kawasaki disease on long-term follow-up: A prospective study from North India.

    abstract:AIM:To study the profile of autoantibodies on long-term follow-up of children with Kawasaki disease (KD). PATIENTS AND METHODS:In this single-center observational cohort study, 50 children who had been diagnosed and treated for KD with a minimum follow-up period of 3 years were enrolled. The organ-specific autoantibod...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.13372

    authors: Basha A,Rawat A,Jindal AK,Gupta A,Anand S,Garg R,Minz RW,Singh S

    更新日期:2018-11-01 00:00:00

  • The immunological basis of B-cell therapy in systemic lupus erythematosus.

    abstract::Loss of B-cell tolerance is a hallmark feature of the pathogenesis in systemic lupus erythematosus (SLE), an autoimmune disease that is characterized by hypergammaglobulinemia and autoantibody production. These autoantibodies lead to formation of immune-complex deposition in internal organs causing inflammation and da...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章,评审

    doi:10.1111/j.1756-185X.2009.01458.x

    authors: Mok MY

    更新日期:2010-02-01 00:00:00

  • The Role of 18F Fluorodeoxyglucose Positron Emission Tomography Scanning in the Diagnosis and Management of Systemic Vasculitis.

    abstract::Primary systemic vasculitis is a group of heterogeneous disorders, characterized by inflammation of blood vessels causing end organ damage from ischemia, aneurysm formation or dissection. Delay in the early diagnosis owing to non-specific symptoms, lack of definitive serological tests, limited availability of biopsy a...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章,评审

    doi:10.1111/1756-185X.12713

    authors: Danve A,O'Dell J

    更新日期:2015-09-01 00:00:00

  • Elevated frequencies of CD4(+) IL-21(+) T, CD4(+) IL-21R(+) T and IL-21(+) Th17 cells, and increased levels of IL-21 in bleomycin-induced mice may be associated with dermal and pulmonary inflammation and fibrosis.

    abstract:AIM:Systemic sclerosis (SSc) is characterized by immune abnormalities, progressive fibrosis of the skin and internal organs, and microvascular injury and damage. Interleukin-21 receptor (IL-21R) is expressed in the epidermis from patients with SSc. However, information describing the role of IL-21 in SSc is limited. M...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.12522

    authors: Lei L,He ZY,Zhao C,Sun XJ,Zhong XN

    更新日期:2016-04-01 00:00:00

  • IL-17A haplotype confers susceptibility to systemic lupus erythematosus but not to rheumatoid arthritis in Mexican patients.

    abstract:AIM:Recent studies highlight the importance of the interleukin (IL)-17A cytokine in systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). There are also reports of associations between some single nucleotide polymorphisms (SNPs) in IL-17A and RA but not SLE. Notably, these findings have not been replicated ...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.13426

    authors: Montúfar-Robles I,Barbosa-Cobos RE,Alemán-Ávila I,Ramírez-Bello J

    更新日期:2019-03-01 00:00:00

  • Inhibition of P-glycoprotein facilitated glycosaminoglycan accumulation during chondrogenesis of human bone marrow mesenchymal stem cells.

    abstract:AIM:P-glycoprotein (P-gp) is an adenosine-5-triphosphate Binding Cassettes B 1 (ABCB1) transporter that exports various substrates on cellular membrane. Surface expression of P-gp was decreased during chondrogenesis of human bone marrow mesenchymal stem cells (BM-MSCs). We examined the role of P-gp in extracellular mat...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/j.1756-185X.2011.01610.x

    authors: Kim SG,Lee AJ,Lee SJ,Suh HS,Shin IH

    更新日期:2011-05-01 00:00:00

  • A multi-center, observational study shows high proportion of Australian rheumatoid arthritis patients have inadequate disease control.

    abstract:OBJECTIVES:To evaluate the disease activity and current pharmacological interventions used to achieve remission in rheumatoid arthritis (RA) patients in Australia. METHODS:Rheumatoid arthritis patients treated in participating Australian clinics were included in the study. Patient demographics, disease onset, medicati...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章,多中心研究

    doi:10.1111/1756-185X.12163

    authors: Littlejohn G,Roberts L,Arnold M,Bird P,Burnet S,de Jager J,Griffiths H,Nicholls D,Scott J,Zochling J,Tymms KE

    更新日期:2013-10-01 00:00:00

  • FCGR3B copy number loss rather than gain is a risk factor for systemic lupus erythematous and lupus nephritis: a meta-analysis.

    abstract:AIM:Some studies have been performed to elucidate the association between Fc gamma receptor 3B (FCGR3B) copy number (CN) and the risk of systemic lupus erythematosus (SLE) and/or lupus nephritis (LN), yet the results remain conflicting. Therefore, we have undertaken a systematic review of all the studies published and ...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/1756-185X.12342

    authors: Yuan J,Zhao D,Wu L,Xu X,Pang Y,Zhang J,Ma Y,Liu J,Wang J

    更新日期:2015-05-01 00:00:00

  • PPARγ agonist rosiglitazone inhibits migration and invasion by downregulating Cyr61 in rheumatoid arthritis fibroblast-like synoviocytes.

    abstract:AIM:Peroxisome proliferator-activated receptor gamma (PPARγ) agonists have anti-inflammatory properties that reduce inflammatory cytokine production in rheumatoid arthritis (RA). Cysteine-rich angiogenic inducer 61 (Cyr61) is associated with diseases related to chronic inflammation. The aim of this study was to investi...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.12913

    authors: Kwon EJ,Park EJ,Choi S,Kim SR,Cho M,Kim J

    更新日期:2017-10-01 00:00:00

  • Risk of hepatitis B reactivation in patients receiving anti-tumor necrosis factor-α therapy.

    abstract:OBJECTIVE:The purpose of this study was to determine hepatitis B virus (HBV) screening rates in patients receiving anti-tumor necrosis factor (TNF)-α therapy and the frequency of HBV reactivation in patients with resolved hepatitis B virus infection (hepatitis B surface antigen [HBsAg] negative, hepatitis B core antibo...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.14034

    authors: Fidan S,Capkın E,Arıca DA,Durak S,Okatan IE

    更新日期:2021-02-01 00:00:00

  • Validity and reliability of the unsupported upper-limb exercise test in individuals with rheumatoid arthritis.

    abstract:BACKGROUND:Rheumatoid arthritis (RA) is a chronic disease which affects the performance of the upper extremities. There is no method to evaluate the specific upper extremity endurance of individuals with this disease. The unsupported upper-limb exercise test (UULEX) is a performance test that evaluates upper extremity ...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.13720

    authors: Cetin SY,Basakci Calik B,Ayan A,Cavlak U

    更新日期:2019-11-01 00:00:00

  • Clinical significance of SLC2A9/GLUT9 rs11722228 polymorphisms in gout.

    abstract:AIM:The main objective of this study is to elucidate the clinical significance of the SLC2A9/GLUT9 rs11722228 polymorphism among male gout patients. METHOD:We consecutively recruited all newly diagnosed male gout patients who were treatment-naive from the rheumatology outpatient clinics of two Malaysian hospitals. Age...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章,多中心研究

    doi:10.1111/1756-185X.12918

    authors: Das Gupta E,Sakthiswary R,Lee SL,Wong SF,Hussein H,Gun SC

    更新日期:2018-03-01 00:00:00

  • Differential clinical presentation of Adamantiades-Behçet's disease in non-endemic and endemic areas: retrospective data from a Middle-European cohort study.

    abstract:OBJECTIVES:To assess demographical and clinical data in a Middle-European cohort of patients with Adamantiades-Behçet's disease (ABD), together with the use of medication in adherence to international guidelines. METHODS:In a retrospective cohort study, in- and outpatients of an Austrian secondary and tertiary univers...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章,多中心研究

    doi:10.1111/1756-185X.13306

    authors: Moosmann T,Veraar C,Brunner J,Fraedrich G,Frech A,Horninger W,Ratzinger G,Streif W,Teuchner B,Willeit J,Zlamy M,De Zordo T,Schirmer M

    更新日期:2018-12-01 00:00:00

  • Histological analysis of synovium by treatment of etanercept for rheumatoid arthritis.

    abstract:AIMS:In order to investigate the histological change in effect attenuation cases of etanercept compared with methotrexate (MTX), we performed immunohistochemical examination by seven different molecules. METHODS:We histologically assessed synovial tissue from five MTX-treated rheumatoid arthritis (RA) patients as cont...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/j.1756-185X.2009.01372.x

    authors: Suzuki Y,Inoue K,Chiba J,Inoue Y,Kanbe K

    更新日期:2009-04-01 00:00:00

  • Apigenin and apigeninidin isolates from the Sorghum bicolor leaf targets inflammation via cyclo-oxygenase-2 and prostaglandin-E2 blockade.

    abstract:AIM:This study evaluated the anti-inflammatory properties of a species of Sorghum bicolor leaf (SBL) grown in West Africa. METHOD:Cyclo-oxygenase (COX)-2:COX-1 selectivity assay was carried out by plating isolated peripheral blood mononuclear cells in culture medium with specific SBL fractions: crude extract (J), ethy...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.13355

    authors: Makanjuola SBL,Ogundaini AO,Ajonuma LC,Dosunmu A

    更新日期:2018-08-01 00:00:00

  • Incidence of gastroduodenal ulcers during treatment with celecoxib or diclofenac: pooled results from three 12-week trials in Chinese patients with osteoarthritis or rheumatoid arthritis.

    abstract:AIM:To test whether treatment with celecoxib reduces the incidence of gastroduodenal ulcers compared to diclofenac in Asian patients with osteoarthritis (OA) or rheumatoid arthritis (RA) with minimal significant risk factors. METHODS:Patients with a clinical diagnosis of OA or RA of at least 3 months were randomized t...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1756-185X.2010.01463.x

    authors: Cheung R,Cheng TT,Dong Y,Lin HY,Lai K,Lau CS,Feng H,Parsons B

    更新日期:2010-05-01 00:00:00

  • Proteomic analysis of bone marrow-adherent cells in rheumatoid arthritis and osteoarthritis.

    abstract:AIM:To elucidate the pathophysiology of rheumatoid arthritis (RA) as well as osteoarthritis (OA), we analyzed protein profiles of bone marrow-derived adherent cells (BMACs) from patients with these diseases. METHODS:Proteins, extracted from BMACs from three RA and three OA patients, were comprehensively analyzed by 2-...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/j.1756-185X.2012.01702.x

    authors: Kamada T,Kurokawa MS,Kato T,Takenouchi K,Takahashi K,Yoshioka T,Uchida T,Mitsui H,Suematsu N,Okamoto K,Yudo K,Katayama Y,Nakamura H

    更新日期:2012-04-01 00:00:00

  • Assessment of the anti-rheumatoid arthritis activity of Gastrodia elata (tian-ma) and Radix aconitic lateralis preparata (fu-zi) via network pharmacology and untargeted metabolomics analyses.

    abstract:AIM:Gastrodia elata and Radix aconiti lateralis preparrata are respectively named as Tian-Ma and Fu-Zi (TF) in Chinese. We explored the active components against rheumatoid arthritis (RA) from an extensively used couplet of Chinese herbs, Gastrodia elata and Radix aconiti lateralis preparata (TF) via untargeted metabol...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.14063

    authors: Yang J,Zhang Y,Li WH,Guo BF,Peng QL,Yao WY,Gong DH,Ding WJ

    更新日期:2021-02-01 00:00:00

  • Differentiation of patented crystalline glucosamine sulfate from other glucosamine preparations will optimize osteoarthritis treatment.

    abstract::Symptomatic slow-acting drugs for osteoarthritis (SYSADOAs) are recommended for the medium- to long-term management of knee osteoarthritis (OA) due to their abilities to control pain, improve function and delay joint structural changes. Among SYSADOAs, evidence is greatest for the patented crystalline glucosamine sulf...

    journal_title:International journal of rheumatic diseases

    pub_type: 社论,评审

    doi:10.1111/1756-185X.13068

    authors: Saengnipanthkul S,Waikakul S,Rojanasthien S,Totemchokchyakarn K,Srinkapaibulaya A,Cheh Chin T,Mai Hong N,Bruyère O,Cooper C,Reginster JY,Lwin M

    更新日期:2019-03-01 00:00:00

  • Translation, cultural adaptation and validation of the WHO fracture risk assessment tool (FRAX(®) ) into Bengali.

    abstract:AIM:To develop a translated and culturally adapted Bengali version of the WHO Fracture Risk Assessment Tool (FRAX(®) ) and to test its feasibility, content validity and reliability. METHOD:The English FRAX was translated and culturally adapted for use in Bangladeshi populations following established forward-backward t...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.12425

    authors: Islam MN,Ferdous N,Ten Klooster PM,Uddin MS,Nasrin S,Pal B,Rasker JJ

    更新日期:2015-03-01 00:00:00

  • A cross-sectional study on factors associated with poor work outcomes in patients with axial spondyloarthritis in Singapore.

    abstract:AIM:Axial spondyloarthritis (axSpA) affects patients in the prime of their economic productivity. We aim to identify factors associated with poor work productivity in patients with axSpA in Singapore. METHODS:A cross-sectional study was performed in two tertiary centers in Singapore. Consecutive adult patients ≥21 yea...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章,多中心研究

    doi:10.1111/1756-185X.13696

    authors: Goh Y,Kwan YH,Leung YY,Fong W,Cheung PP

    更新日期:2019-11-01 00:00:00

  • Impact of peer-led group education on the quality of life in patients with ankylosing spondylitis.

    abstract:OBJECTIVES:To determine the effect of peer-led group education on the quality of life and depression in patients with ankylosing spondylitis (AS). METHODS:Eighty patients with definite AS were allocated randomly to either the education or control group. The education group (n = 40) was subjected to a peer-led group ed...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/1756-185X.12256

    authors: Kaya T,Goksel Karatepe A,Atici Ozturk P,Gunaydin R

    更新日期:2016-02-01 00:00:00

  • Serum levels of anti-streptolysin O antibodies: their role in evaluating rheumatic diseases.

    abstract:BACKGROUND:Family physicians measure serum levels of anti-streptolysin O antibodies (ASO) in the routine evaluation of patients with rheumatic conditions. AIM:To evaluate the significance of elevated serum ASO titer in hospitalized patients with various clinical conditions. PATIENTS AND METHODS:We retrieved the names...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/j.1756-185X.2011.01668.x

    authors: Ben-Chetrit E,Moses AE,Agmon-Levin N,Block C,Ben-Chetrit E

    更新日期:2012-02-01 00:00:00

  • A study of the prevalence of sicca symptoms and secondary Sjögren's syndrome in patients with rheumatoid arthritis, and its association to disease activity and treatment profile.

    abstract:AIM:To examine the prevalence of sicca symptoms and secondary Sjögren's syndrome (sSS) in rheumatoid arthritis (RA) patients, and the impact of sSS on disease activity and treatment profile in RA patients. METHODS:Three hundred and seven RA patients responding positive to at least one of the questions in a questionnai...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/j.1756-185X.2012.01717.x

    authors: Haga HJ,Naderi Y,Moreno AM,Peen E

    更新日期:2012-06-01 00:00:00

  • Hand bone mineral density reference values in a Turkish healthy female population.

    abstract:AIM:In this study we aimed at identifying the bone mineral density (BMD) reference values of hands, according to age, measured by dual-energy X-ray absorptiometry (DEXA) and assessing the correlation of these values with lumbar and femoral BMD values. METHOD:A total of 403 healthy women aged between 20 and 70 particip...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.12159

    authors: Alioglu K,Dogu B,Sirzai H,Yilmaz F,Kuran B

    更新日期:2017-12-01 00:00:00

  • Clinical and psychosocial factors associated with depression and anxiety in Singaporean patients with rheumatoid arthritis.

    abstract:AIM:To assess the frequency of, and factors associated with, depression and anxiety in Singaporean patients with rheumatoid arthritis (RA). METHOD:One hundred RA patients were recruited in a cross-sectional study. Socio-demographics, severity of anxiety and depression, disease activity, levels of serological markers a...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/j.1756-185X.2010.01591.x

    authors: Ho RC,Fu EH,Chua AN,Cheak AA,Mak A

    更新日期:2011-02-01 00:00:00

  • Peripheral neuropathies in rheumatic diseases: More diverse and frequent than expected. A cross-sectional study.

    abstract:BACKGROUND/OBJECTIVE:Peripheral neuropathies (PN) are heterogeneous nerve disorders; frequently rheumatic patients have neuropathic symptoms. In some rheumatic diseases (RD) PN are secondary to nerve compression while others are related to metabolic abnormalities, inflammation or vasculitis. Our aim was to explore the ...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.13755

    authors: López-López CO,Montes Castillo ML,Soto-Fajardo RC,Sandoval-García LF,Loyola-Sánchez A,Burgos-Vargas R,Peláez-Ballestas I,Álvarez Hernández E,Vázquez-Mellado J

    更新日期:2020-02-01 00:00:00

  • Gout: an Asia-Pacific update.

    abstract::Even though, Hippocrates recognized gout as an affection of older men and a product of high living long back in 5th century BC, this painful condition promises to accompany humanity to the 21st century. The incidence is progressively rising and females are also affected in the modern era. There are also regional and e...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章,评审

    doi:10.1111/1756-185X.13103

    authors: Paul BJ,James R

    更新日期:2017-04-01 00:00:00

  • Musculoskeletal symptoms and disorders among 350 garment workers in Bangladesh: A cross-sectional pilot study.

    abstract:OBJECTIVE:To study the prevalence of musculoskeletal (MSK) symptoms and disorders among garment workers in Bangladesh, to look for possible relationships between pain location and type of work performed and to estimate the prevalence of rheumatological diagnoses. METHODS:A cross-sectional pilot study among 350 garment...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.13423

    authors: Shazzad MN,Ahmed S,Haq SA,Islam MN,Abu Shahin M,Choudhury MR,Hasan ATMT,Abdal SJ,Rasker JJ

    更新日期:2018-12-01 00:00:00

  • Reactivation of hepatitis B virus infection following rituximab treatment in HBsAg-negative, HBcAb-positive rheumatoid arthritis patients: A long-term, real-world observation.

    abstract:AIM:Longitudinal data of the reactivation of hepatitis B virus (rHBV) and serial serological markers or HBV-DNA has been limited. This study aimed to investigate the temporal course of rHBV development in rheumatoid arthritis (RA) patients undergoing long-term rituximab therapy. METHODS:The occurrence of rHBV was exam...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.13582

    authors: Chen YM,Chen HH,Huang WN,Chen YH,Hsieh TY,Yang SS,Lan JL,Chen DY

    更新日期:2019-06-01 00:00:00