Automatic B cell lymphoma detection using flow cytometry data.

abstract：BACKGROUND:The milk fat profile of the Danish Holstein (DH) and Danish Jersey (DJ) show clear differences. Identification of the genomic regions, genes and biological pathways underlying the milk fat biosynthesis will improve the understanding of the biology underlying bovine milk fat production and may provide new pos...

journal_title：BMC genomics

authors： Buitenhuis B,Janss LL,Poulsen NA,Larsen LB,Larsen MK,Sørensen P

更新日期：2014-12-15 00:00:00

abstract：BACKGROUND:Fusarium verticillioides causes ear rot in maize (Zea mays L.) and accumulation of mycotoxins, that affect human and animal health. Currently, chemical and agronomic measures to control Fusarium ear rot are not very effective and selection of more resistant genotypes is a desirable strategy to reduce contami...

journal_title：BMC genomics

authors： Lanubile A,Ferrarini A,Maschietto V,Delledonne M,Marocco A,Bellin D

更新日期：2014-08-25 00:00:00

abstract：BACKGROUND:Gene duplication is an important biological phenomenon associated with genomic redundancy, degeneration, specialization, innovation, and speciation. After duplication, both copies continue functioning when natural selection favors duplicated protein function or expression, or when mutations make them functio...

journal_title：BMC genomics

authors： Chain FJ,Dushoff J,Evans BJ

更新日期：2011-12-12 00:00:00

abstract：BACKGROUND:Copy number variation is an important component of genetic variation in higher eukaryotes. The extent of natural copy number variation in C. elegans is unknown outside of 2 highly divergent wild isolates and the canonical N2 Bristol strain. RESULTS:We have used array comparative genomic hybridization (aCGH)...

journal_title：BMC genomics

authors： Maydan JS,Lorch A,Edgley ML,Flibotte S,Moerman DG

更新日期：2010-01-25 00:00:00

abstract：BACKGROUND:Phenylalanine ammonia lyase (PAL) is a key enzyme of the phenylpropanoid pathway that catalyzes the deamination of phenylalanine to trans-cinnamic acid, a precursor for the lignin and flavonoid biosynthetic pathways. To date, PAL genes have been less extensively studied in gymnosperms than in angiosperms. Ou...

journal_title：BMC genomics

authors： Bagal UR,Leebens-Mack JH,Lorenz WW,Dean JF

更新日期：2012-06-11 00:00:00

abstract：BACKGROUND:Hibernation is a physiological state exploited by many animals exposed to prolonged adverse environmental conditions associated with winter. Large changes in metabolism and cellular function occur, with many stress response pathways modulated to tolerate physiological challenges that might otherwise be letha...

journal_title：BMC genomics

authors： Capraro A,O'Meally D,Waters SA,Patel HR,Georges A,Waters PD

更新日期：2019-06-06 00:00:00

abstract：BACKGROUND:Initial interest in Dechloromonas aromatica strain RCB arose from its ability to anaerobically degrade benzene. It is also able to reduce perchlorate and oxidize chlorobenzoate, toluene, and xylene, creating interest in using this organism for bioremediation. Little physiological data has been published for ...

journal_title：BMC genomics

authors： Salinero KK,Keller K,Feil WS,Feil H,Trong S,Di Bartolo G,Lapidus A

更新日期：2009-08-03 00:00:00

abstract：BACKGROUND:Gene knockouts are a critical resource for functional genomics. In Arabidopsis, comprehensive knockout collections were generated by amplifying and sequencing genomic DNA flanking insertion mutants. These Flanking Sequence Tags (FSTs) map each mutant to a specific locus within the genome. In maize, FSTs have...

journal_title：BMC genomics

authors： Settles AM,Holding DR,Tan BC,Latshaw SP,Liu J,Suzuki M,Li L,O'Brien BA,Fajardo DS,Wroclawska E,Tseung CW,Lai J,Hunter CT 3rd,Avigne WT,Baier J,Messing J,Hannah LC,Koch KE,Becraft PW,Larkins BA,McCarty DR

更新日期：2007-05-09 00:00:00

abstract：BACKGROUND:Streptococcus pneumoniae causes over one million deaths worldwide annually, despite recent developments in vaccine and antibiotic therapy. Host susceptibility to pneumococcal infection and disease is controlled by a combination of genetic and environmental influences, but current knowledge remains limited. ...

journal_title：BMC genomics

authors： Wisby L,Fernandes VE,Neill DR,Kadioglu A,Andrew PW,Denny P

更新日期：2013-04-11 00:00:00

abstract：BACKGROUND:Pyrethroid resistance in Anopheles funestus populations has led to an increase in malaria transmission in southern Africa. Resistance has been attributed to elevated activities of cytochrome P450s but the molecular basis underlying this metabolic resistance is unknown. Microsatellite and SNP markers were use...

journal_title：BMC genomics

authors： Wondji CS,Morgan J,Coetzee M,Hunt RH,Steen K,Black WC 4th,Hemingway J,Ranson H

更新日期：2007-01-29 00:00:00

abstract：BACKGROUND:Shotgun sequencing of environmental DNA is an essential technique for characterizing uncultivated microbes in situ. However, the taxonomic and functional assignment of the obtained sequence fragments remains a pressing problem. RESULTS:Existing algorithms are largely optimized for speed and coverage; in con...

journal_title：BMC genomics

authors： Stark M,Berger SA,Stamatakis A,von Mering C

更新日期：2010-08-05 00:00:00

abstract：BACKGROUND:Chlamydomonas reinhardtii is the model organism that serves as a reference for studies in algal genomics and physiology. It is of special interest in the study of the evolution of regulatory pathways from algae to higher plants. Additionally, it has recently gained attention as a potential source for bio-fue...

journal_title：BMC genomics

authors： Romero-Campero FJ,Perez-Hurtado I,Lucas-Reina E,Romero JM,Valverde F

更新日期：2016-03-12 00:00:00

abstract：:We describe an emerging initiative - the 'Functional Annotation of All Salmonid Genomes' (FAASG), which will leverage the extensive trait diversity that has evolved since a whole genome duplication event in the salmonid ancestor, to develop an integrative understanding of the functional genomic basis of phenotypic var...

journal_title：BMC genomics

authors： Macqueen DJ,Primmer CR,Houston RD,Nowak BF,Bernatchez L,Bergseth S,Davidson WS,Gallardo-Escárate C,Goldammer T,Guiguen Y,Iturra P,Kijas JW,Koop BF,Lien S,Maass A,Martin SAM,McGinnity P,Montecino M,Naish KA,Nichols K

更新日期：2017-06-27 00:00:00

abstract：BACKGROUND:New gene emergence is so far assumed to be mostly driven by duplication and divergence of existing genes. The possibility that entirely new genes could emerge out of the non-coding genomic background was long thought to be almost negligible. With the increasing availability of fully sequenced genomes across ...

journal_title：BMC genomics

authors： Neme R,Tautz D

更新日期：2013-02-21 00:00:00

abstract：BACKGROUND:Dystonia1 (DYT1) dystonia is caused by a glutamic acid deletion (ΔE) mutation in the gene encoding Torsin A in humans (HTorA). To investigate the unknown molecular and cellular mechanisms underlying DYT1 dystonia, we performed an unbiased proteomic analysis. RESULTS:We found that the amount of proteins and ...

journal_title：BMC genomics

authors： Kim AY,Seo JB,Kim WT,Choi HJ,Kim SY,Morrow G,Tanguay RM,Steller H,Koh YH

更新日期：2015-04-23 00:00:00

abstract：BACKGROUND:In silico, secretome proteins can be predicted from completely sequenced genomes using various available algorithms that identify membrane-targeting sequences. For metasecretome (collection of surface, secreted and transmembrane proteins from environmental microbial communities) this approach is impractical,...

journal_title：BMC genomics

authors： Ciric M,Moon CD,Leahy SC,Creevey CJ,Altermann E,Attwood GT,Rakonjac J,Gagic D

更新日期：2014-05-12 00:00:00

abstract：BACKGROUND:Cultivated watermelon [Citrullus lanatus (Thunb.) Matsum. & Nakai var. lanatus] is an important agriculture crop world-wide. The fruit of watermelon undergoes distinct stages of development with dramatic changes in its size, color, sweetness, texture and aroma. In order to better understand the genetic and m...

journal_title：BMC genomics

authors： Guo S,Liu J,Zheng Y,Huang M,Zhang H,Gong G,He H,Ren Y,Zhong S,Fei Z,Xu Y

更新日期：2011-09-21 00:00:00

abstract：BACKGROUND:Increasing evidence suggests that overlapping genes are much more common in eukaryotic genomes than previously thought. In this study we identified and characterized the overlapping genes in a set of 13,484 pairs of human-mouse orthologous genes. RESULTS:About 10% of the genes under study are overlapping ge...

journal_title：BMC genomics

authors： Sanna CR,Li WH,Zhang L

更新日期：2008-04-14 00:00:00

abstract：BACKGROUND:Human interfollicular epidermis is sustained by the proliferation of stem cells and their progeny, transient amplifying cells. Molecular characterization of these two cell populations is essential for better understanding of self renewal, differentiation and mechanisms of skin pathogenesis. The purpose of th...

journal_title：BMC genomics

authors： Koçer SS,Djurić PM,Bugallo MF,Simon SR,Matic M

更新日期：2008-07-30 00:00:00

abstract：BACKGROUND:Evolution of novel protein-coding genes is the bedrock of adaptive evolution. Recently, we identified six protein-coding genes with similar signal sequence from Schistosoma japonicum egg stage mRNA using signal sequence trap (SST). To find the mechanism underlying the origination of these genes with similar ...

journal_title：BMC genomics

authors： Mbanefo EC,Chuanxin Y,Kikuchi M,Shuaibu MN,Boamah D,Kirinoki M,Hayashi N,Chigusa Y,Osada Y,Hamano S,Hirayama K

更新日期：2012-06-20 00:00:00

abstract：BACKGROUND:Pitayas are currently attracting considerable interest as a tropical fruit with numerous health benefits. However, as a long-day plant, pitaya plants cannot flower in the winter season from November to April in Hainan, China. To harvest pitayas with high economic value in the winter season, it is necessary t...

journal_title：BMC genomics

authors： Xiong R,Liu C,Xu M,Wei SS,Huang JQ,Tang H

更新日期：2020-04-29 00:00:00

abstract：BACKGROUND:Transposable elements are selfish genetic sequences which only occasionally provide useful functions to their host species. In addition, models of mobile element evolution assume a second type of selfishness: elements of different families do not cooperate, but they independently fight for their survival in ...

journal_title：BMC genomics

authors： Marco A,Marín I

更新日期：2008-05-14 00:00:00

abstract：BACKGROUND:Lipopolysaccharide (LPS) from Gram-negative bacteria cause innate immune responses in animals and plants. The molecules involved in LPS signaling in animals are well studied, whereas those in plants are not yet as well documented. Recently, we identified Arabidopsis AtLBR-2, which binds to LPS from Pseudomon...

journal_title：BMC genomics

authors： Iizasa S,Iizasa E,Watanabe K,Nagano Y

更新日期：2017-12-29 00:00:00

abstract：BACKGROUND:Although the study of gene regulation via the action of specific microRNAs (miRNAs) has experienced a boom in recent years, the analysis of genome-wide interaction networks among miRNAs and respective targeted mRNAs has lagged behind. MicroRNAs simultaneously target many transcripts and fine-tune the express...

journal_title：BMC genomics

authors： Nunez YO,Truitt JM,Gorini G,Ponomareva ON,Blednov YA,Harris RA,Mayfield RD

更新日期：2013-10-22 00:00:00

abstract：BACKGROUND:Free asparagine is the precursor for acrylamide formation during cooking and processing of grains, tubers, beans and other crop products. In wheat grain, free asparagine, free glutamine and total free amino acids accumulate to high levels in response to sulphur deficiency. In this study, RNA-seq data were ac...

journal_title：BMC genomics

authors： Curtis TY,Raffan S,Wan Y,King R,Gonzalez-Uriarte A,Halford NG

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Nitrogen (N) is a key macronutrient required for plant growth and development. In this study, watermelon plants were grown under hydroponic conditions at 0.2 mM N, 4.5 mM N, and 9 mM N for 14 days. RESULTS:Dry weight and photosynthetic assimilation at low N (0.2 mM) was reduced by 29 and 74% compared with h...

journal_title：BMC genomics

authors： Nawaz MA,Chen C,Shireen F,Zheng Z,Sohail H,Afzal M,Ali MA,Bie Z,Huang Y

更新日期：2018-06-13 00:00:00

abstract：BACKGROUND:The epithelium is the first line of defense against pathogens. Notably the epithelial cells lining the respiratory track are crucial in sensing airborne microbes and mounting an effective immune response via the expression of target genes such as cytokines and chemokines. Gene expression regulation following...

journal_title：BMC genomics

authors： Borghini L,Hibberd M,Davila S

更新日期：2018-12-27 00:00:00

abstract：BACKGROUND:The programmed cell death 2 (Pdcd2) gene on mouse chromosome 17 was evaluated as a member of a highly conserved synteny, a candidate for an imprinted locus, and a candidate for the Hybrid sterility 1 (Hst1) gene. RESULTS:New mouse transcripts were identified at this locus: an alternative Pdcd2 mRNA skipping...

journal_title：BMC genomics

authors： Mihola O,Forejt J,Trachtulec Z

更新日期：2007-01-18 00:00:00

abstract：BACKGROUND:Phlebotomine sand flies (Diptera, Nematocera) are important vectors of several pathogens, including Leishmania parasites, causing serious diseases of humans and dogs. Despite their importance as disease vectors, most aspects of sand fly biology remain unknown including the molecular basis of their reproducti...

journal_title：BMC genomics

authors： Petrella V,Aceto S,Colonna V,Saccone G,Sanges R,Polanska N,Volf P,Gradoni L,Bongiorno G,Salvemini M

更新日期：2019-06-25 00:00:00

abstract：BACKGROUND:Thousands of intragenic long interspersed element 1 sequences (LINE-1 elements or L1s) reside within genes. These intragenic L1 sequences are conserved and regulate the expression of their host genes. When L1 methylation is decreased, either through chemical induction or in cancer, the intragenic L1 transcri...

journal_title：BMC genomics

authors： Wanichnopparat W,Suwanwongse K,Pin-On P,Aporntewan C,Mutirangura A

更新日期：2013-03-27 00:00:00